Page last updated: 2024-10-22

acetazolamide and Cataract

acetazolamide has been researched along with Cataract in 34 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"To confirm the prophylactic effect of oral acetazolamide against increased intraocular pressure (IOP) in the period immediately after cataract surgery in eyes with primary open-angle glaucoma (POAG) and to evaluate the appropriate administration time of oral acetazolamide to prevent IOP elevation."9.24Prophylactic Effect of Oral Acetazolamide against Intraocular Pressure Elevation after Cataract Surgery in Eyes with Glaucoma. ( Hayashi, K; Manabe, SI; Yoshida, M; Yoshimura, K, 2017)
" Pseudophakic cystoid macular edema (PCME) was diagnosed, and treatment with oral acetazolamide was tried without success."8.31Intravitreal acetazolamide implant for pseudophakic cystoid macular edema. ( da Silva Cunha, A; da Silva, PHR; de Azevedo Bastos, TM; Fernandes, C; Fialho, SL; Jorge, R; Messias, A; Scott, IU; Villela, IF, 2023)
"Goal - measurement of Diacarb (Acetazolamide) and Timolol effectiveness for prevention of cataract phacoemulsification complications."8.02ROLE OF DIACARAB (ACETAZOLAMIDE) AND TIMOLOL PREMEDICATION IN PREVENTION OF CATARACT PHACOEMULSIFICATION COMPLICATIONS. ( Aleksidze, A; Javrishvili, V; Shurgaia, A; Todria, M, 2021)
"BACKGROUND Acetazolamide (ACTZ) is commonly used in the prevention and treatment of various clinical conditions, and anuric acute kidney injury (AKI) is one of its known life-threatening complications."8.02Anuric Acute Kidney Injury Requiring Dialysis Following Acetazolamide Use for Cataract Surgery. ( Abou-Mrad, RM; Babu, RS; Ibrahim, M; Osman, N, 2021)
"To confirm the prophylactic effect of oral acetazolamide against increased intraocular pressure (IOP) in the period immediately after cataract surgery in eyes with primary open-angle glaucoma (POAG) and to evaluate the appropriate administration time of oral acetazolamide to prevent IOP elevation."5.24Prophylactic Effect of Oral Acetazolamide against Intraocular Pressure Elevation after Cataract Surgery in Eyes with Glaucoma. ( Hayashi, K; Manabe, SI; Yoshida, M; Yoshimura, K, 2017)
"This study evaluated the effects of acetazolamide, latanoprost, travoprost, bimatoprost, brimonidine, brinzolamide, and timolol on pain during phacoemulsification cataract surgery."5.17Effect of prophylactic intraocular pressure-lowering medication on pain during cataract surgery. ( Balbaba, M; Çelebi, S; Ulaş, F, 2013)
" Pseudophakic cystoid macular edema (PCME) was diagnosed, and treatment with oral acetazolamide was tried without success."4.31Intravitreal acetazolamide implant for pseudophakic cystoid macular edema. ( da Silva Cunha, A; da Silva, PHR; de Azevedo Bastos, TM; Fernandes, C; Fialho, SL; Jorge, R; Messias, A; Scott, IU; Villela, IF, 2023)
"Goal - measurement of Diacarb (Acetazolamide) and Timolol effectiveness for prevention of cataract phacoemulsification complications."4.02ROLE OF DIACARAB (ACETAZOLAMIDE) AND TIMOLOL PREMEDICATION IN PREVENTION OF CATARACT PHACOEMULSIFICATION COMPLICATIONS. ( Aleksidze, A; Javrishvili, V; Shurgaia, A; Todria, M, 2021)
"BACKGROUND Acetazolamide (ACTZ) is commonly used in the prevention and treatment of various clinical conditions, and anuric acute kidney injury (AKI) is one of its known life-threatening complications."4.02Anuric Acute Kidney Injury Requiring Dialysis Following Acetazolamide Use for Cataract Surgery. ( Abou-Mrad, RM; Babu, RS; Ibrahim, M; Osman, N, 2021)
"The IOP 1-day postoperatively was analysed against the last recorded IOP before phacoemulsification in a cohort of patients with glaucoma or OHT who underwent uncomplicated phacoemulsification cataract surgery between December 2009 and September 2012, where it was routine practice to give acetazolamide postoperatively."3.81Is the 1-day postoperative IOP check needed post uncomplicated phacoemulsification in patients with glaucoma and ocular hypertension? ( Gupta, A; Vernon, SA, 2015)
" The use of systemic acetazolamide provided significant control of IOP and could be considered a 'possible standard' management of cataract surgery in POAG patients."3.78Short-term changes in intraocular pressure after phacoemulsification in glaucoma patients. ( Centofanti, M; Digiuni, M; Fea, A; Figus, M; Fogagnolo, P; Frezzotti, P; Lembo, A; Ligorio, P; Lorenzi, U; Rossetti, L, 2012)
"Glaucoma is the leading cause of irreversible blindness worldwide and is often undetected in resource-limited settings."1.72Intraocular pressure screening during high-volume cataract surgery outreach in Ethiopia. ( McClain, IJ; Rooney, DM; Tabin, GC, 2022)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199023 (67.65)18.7374
1990's0 (0.00)18.2507
2000's1 (2.94)29.6817
2010's5 (14.71)24.3611
2020's5 (14.71)2.80

Authors

AuthorsStudies
Javrishvili, V1
Aleksidze, A1
Shurgaia, A1
Todria, M1
McClain, IJ1
Rooney, DM1
Tabin, GC1
Diafas, A1
Dastiridou, A1
Samouilidou, M1
Tzamalis, A1
Mataftsi, A1
Tsinopoulos, I1
Kozobolis, V1
Ziakas, N1
Jorge, R1
Villela, IF1
Fernandes, C1
de Azevedo Bastos, TM1
Scott, IU1
da Silva Cunha, A1
Fialho, SL1
da Silva, PHR1
Messias, A1
Abou-Mrad, RM1
Ibrahim, M1
Osman, N1
Babu, RS1
Hayashi, K2
Yoshida, M2
Manabe, SI2
Yoshimura, K2
Ulaş, F1
Balbaba, M1
Çelebi, S1
Gupta, A1
Vernon, SA1
Fogagnolo, P1
Centofanti, M1
Figus, M1
Frezzotti, P1
Fea, A1
Ligorio, P1
Lembo, A1
Digiuni, M1
Lorenzi, U1
Rossetti, L1
MURPHY, EU1
BEGUE, H1
AGARWAL, LP2
MALIK, SR2
SCHRADER, K1
CARBALLO, F1
GUPTA, RB1
AURICCHIO, G1
DIOTALLEVI, M1
HARLEY, JD1
FARRAR, JF1
GRAY, JB1
DUNLOP, IC1
HARRISON, R1
Oksala, A2
Varonen, ER1
Quigley, HA1
Hitchings, R1
Ganias, F1
Demailly, P1
Nissen, OI1
Hoppe, RF1
Lantz, JM1
Quigley, JH1
Kornzweig, AL1
Johnson, SB1
Sood, GC1
Sofat, BK1
Chandel, RD1
Mehrotra, SK1
Laatkainen, L1
Hopkins, DJ1
Horan, EC1
Williamson, J1
Russell, F1
Doig, WM1
Paterson, RW1
Pohjola, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Aqueous Humour Release (Burping) Performed at the Slit-lamp to Treat Acute Intraocular Pressure (IOP) Spikes Post-cataract Surgery[NCT03500809]20 participants (Anticipated)Interventional2018-08-12Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for acetazolamide and Cataract

ArticleYear
[Glaucoma].
    Archives d'ophtalmologie et revue generale d'ophtalmologie, 1968, Volume: 28, Issue:2

    Topics: Acetazolamide; Angiography; Aqueous Humor; Cataract; Cholinesterase Inhibitors; Chronic Disease; Dex

1968

Trials

2 trials available for acetazolamide and Cataract

ArticleYear
Effect of prophylactic intraocular pressure-lowering medication on pain during cataract surgery.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2013, Volume: 29, Issue:7

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimoni

2013
Prophylactic Effect of Oral Acetazolamide against Intraocular Pressure Elevation after Cataract Surgery in Eyes with Glaucoma.
    Ophthalmology, 2017, Volume: 124, Issue:5

    Topics: Acetazolamide; Administration, Oral; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors;

2017

Other Studies

31 other studies available for acetazolamide and Cataract

ArticleYear
ROLE OF DIACARAB (ACETAZOLAMIDE) AND TIMOLOL PREMEDICATION IN PREVENTION OF CATARACT PHACOEMULSIFICATION COMPLICATIONS.
    Georgian medical news, 2021, Issue:318

    Topics: Acetazolamide; Cataract; Humans; Phacoemulsification; Premedication; Timolol

2021
Intraocular pressure screening during high-volume cataract surgery outreach in Ethiopia.
    BMC ophthalmology, 2022, Oct-05, Volume: 22, Issue:1

    Topics: Acetazolamide; Cataract; Cross-Sectional Studies; Ethiopia; Glaucoma; Humans; Intraocular Pressure;

2022
The effect of acetazolamide on the retinal and choroidal vasculature of the macula and the optic disc using OCT angiography.
    Archivos de la Sociedad Espanola de Oftalmologia, 2023, Volume: 98, Issue:3

    Topics: Acetazolamide; Aged; Aged, 80 and over; Cataract; Choroid; Cross-Sectional Studies; Fluorescein Angi

2023
Intravitreal acetazolamide implant for pseudophakic cystoid macular edema.
    Documenta ophthalmologica. Advances in ophthalmology, 2023, Volume: 147, Issue:1

    Topics: Acetazolamide; Cataract; Cataract Extraction; Electroretinography; Female; Humans; Intravitreal Inje

2023
Anuric Acute Kidney Injury Requiring Dialysis Following Acetazolamide Use for Cataract Surgery.
    The American journal of case reports, 2021, Apr-23, Volume: 22

    Topics: Acetazolamide; Acute Kidney Injury; Anuria; Cataract; Humans; Male; Middle Aged; Renal Dialysis

2021
Reply.
    Journal of cataract and refractive surgery, 2018, Volume: 44, Issue:6

    Topics: Acetazolamide; Cataract; Exfoliation Syndrome; Humans; Intraocular Pressure; Tonometry, Ocular

2018
Is the 1-day postoperative IOP check needed post uncomplicated phacoemulsification in patients with glaucoma and ocular hypertension?
    Eye (London, England), 2015, Volume: 29, Issue:10

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cataract; Female; Glau

2015
Short-term changes in intraocular pressure after phacoemulsification in glaucoma patients.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2012, Volume: 228, Issue:3

    Topics: Acetazolamide; Administration, Oral; Aged; Carbonic Anhydrase Inhibitors; Cataract; Glaucoma, Open-A

2012
Diamox in cataract wound healing.
    American journal of ophthalmology, 1955, Volume: 39, Issue:1

    Topics: Acetazolamide; Cataract; Cataract Extraction; Diuretics; Lens, Crystalline; Wound Healing

1955
[Diamox in delayed formation of the anterior chamber after cataract operation].
    Bulletin des societes d'ophtalmologie de France, 1955, Issue:9

    Topics: Acetazolamide; Anterior Chamber; Cataract; Cataract Extraction; Diuretics; Eye; Hydro-Lyases; Lens,

1955
Diamox (acetazoleamide) in cataract surgery.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1957, Volume: 133, Issue:3

    Topics: Acetazolamide; Cataract; Cataract Extraction; Humans; Lens, Crystalline

1957
[Diamox therapy in the prevention of anterior chamber hemorrhage following cataract operations].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1958, Volume: 135, Issue:3

    Topics: Acetazolamide; Anterior Chamber; Cataract; Cataract Extraction; Eye Hemorrhage; Humans; Lens, Crysta

1958
[Clinical treatment of the incipient cataract].
    Revista de la Asociacion Medica Argentina, 1958, Volume: 72, Issue:1

    Topics: Acetazolamide; Ascorbic Acid; Cataract; Folic Acid; Humans; Vitamin B Complex; Vitamins

1958
Drug administration in cataract surgery.
    The British journal of ophthalmology, 1959, Volume: 43, Issue:5

    Topics: Acetazolamide; Cataract; Cataract Extraction; Chlorpromazine; Curare; Humans; Lens, Crystalline

1959
[A NEW METHOD FOR THE MEASUREMENT OF THE RATE OF FORMATION OF AQUEOUS HUMOR: THE "RECOVERY RATE" ACCORDING TO OKUN].
    Bollettino d'oculistica, 1963, Volume: 42

    Topics: Acetazolamide; Aqueous Humor; Cataract; Diabetic Retinopathy; Eye Diseases; Glaucoma; Humans; Intrao

1963
AROMATIC DRUGS AND CONGENITAL CATARACTS.
    Lancet (London, England), 1964, Feb-29, Volume: 1, Issue:7331

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Acetazolamide; Anti-Bacterial Agents; Cardiovascular Age

1964
COMPLICATIONS OF CATARACT SUGERY IN GLAUCOMATOUS EYES.
    International ophthalmology clinics, 1964, Volume: 4

    Topics: Acetazolamide; Cataract; Cataract Extraction; Drug Therapy; Glaucoma; Humans; Miotics; Phenylephrine

1964
Treatment of traumatic hyphaema.
    The British journal of ophthalmology, 1967, Volume: 51, Issue:5

    Topics: Acetazolamide; Adolescent; Adult; Aged; Cataract; Child; Child, Preschool; Cortisone; Eye Diseases;

1967
Choroidal detachment after iridencleisis; its occurrence and the results of conservative treatment.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1967, Volume: 153, Issue:1

    Topics: Acetazolamide; Adult; Age Factors; Aged; Atropine; Cataract; Choroid; Eye Diseases; Glaucoma; Humans

1967
A reevaluation of glaucoma management.
    International ophthalmology clinics, 1984,Fall, Volume: 24, Issue:3

    Topics: Acetazolamide; Cataract; Costs and Cost Analysis; Drug-Related Side Effects and Adverse Reactions; E

1984
Traumatic glaucoma.
    Journal of glaucoma, 2001, Volume: 10, Issue:5

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Cataract; Eye Injuries; Glaucoma; Golf; Humans;

2001
Combined thermotrabeculocanalotomy cataract extraction.
    Annals of ophthalmology, 1979, Volume: 11, Issue:4

    Topics: Acetazolamide; Aged; Cataract; Cataract Extraction; Cautery; Eye Injuries; Glaucoma; Humans; Intraoc

1979
The facility of aqueous outflow calculated from the rate of fall in applanation pressure after intravenous acetazolamide in man.
    Acta ophthalmologica, 1974, Volume: 52, Issue:3

    Topics: Acetazolamide; Adolescent; Adult; Aged; Aqueous Humor; Cataract; Diabetes Mellitus; Epinephrine; Eye

1974
Intraocular pressure after cataract extraction: effects of alpha chymotrypsin.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1973, Volume: 8, Issue:2

    Topics: Acetazolamide; Aged; Cataract; Cataract Extraction; Chymotrypsin; Glaucoma; Humans; Intraocular Pres

1973
Diagnosis and treatment of common eye diseases in the aged: guidelines for the practicing physician.
    Journal of the American Geriatrics Society, 1973, Volume: 21, Issue:11

    Topics: Acetazolamide; Age Factors; Aged; Cataract; Cataract Extraction; Cholinesterase Inhibitors; Diabetes

1973
Combined cataract extraction and scleral cautery (includes 8-year followup in 9 cases).
    Annals of ophthalmology, 1971, Volume: 3, Issue:10

    Topics: Acetazolamide; Cataract; Cataract Extraction; Cautery; Conjunctiva; Echothiophate Iodide; Epinephrin

1971
Prognosis in spontaneous phakolytic glaucoma.
    The British journal of ophthalmology, 1972, Volume: 56, Issue:8

    Topics: Acetazolamide; Adrenal Cortex Hormones; Aged; Cataract; Cataract Extraction; Glaucoma; Humans; Male;

1972
Late results of surgery on eyes with primary glaucoma and cataract.
    Acta ophthalmologica, 1971, Volume: 49, Issue:2

    Topics: Acetazolamide; Aged; Cataract; Cataract Extraction; Epinephrine; Glaucoma; Humans; Intraocular Press

1971
Glaucoma in the Hallermann-Streiff syndrome.
    The British journal of ophthalmology, 1970, Volume: 54, Issue:6

    Topics: Acetazolamide; Adult; Cataract; Child, Preschool; Epinephrine; Female; Glaucoma; Hallermann's Syndro

1970
Estimation of sodium fusidate levels in human serum, aqueous humour, and vitreous body.
    The British journal of ophthalmology, 1970, Volume: 54, Issue:2

    Topics: Acetazolamide; Aged; Aqueous Humor; Cataract; Cataract Extraction; Female; Fusidic Acid; Humans; Mal

1970
The glucose content of the aqueous humour in man.
    Acta ophthalmologica, 1966

    Topics: Acetazolamide; Adolescent; Adult; Aged; Animals; Aqueous Humor; Cataract; Diabetes Mellitus; Female;

1966