acetazolamide has been researched along with Carcinoma, Lewis Lung in 3 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Its most potent inhibition rate on lung metastases was reach to 77." | 1.32 | The protein profile of acetazolamide-treated sera in mice bearing Lewis neoplasm. ( Li, XJ; Ma, B; Xiang, Y; Yu, HM, 2004) |
| "Acetazolamide can suppress tumor metastasis, at least in part, by inhibiting the expression of AQP1." | 1.31 | Acetazolamide suppresses tumor metastasis and related protein expression in mice bearing Lewis lung carcinoma. ( Li, T; Li, XJ; Ma, B; Xiang, Y; Yu, HM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiang, Y | 3 |
| Ma, B | 3 |
| Li, T | 2 |
| Yu, HM | 3 |
| Li, XJ | 3 |
| Gao, JW | 1 |
3 other studies available for acetazolamide and Carcinoma, Lewis Lung
| Article | Year |
|---|---|
Acetazolamide suppresses tumor metastasis and related protein expression in mice bearing Lewis lung carcinoma.
Topics: Acetazolamide; Actins; Animals; Antineoplastic Agents; Aquaporin 1; Aquaporins; Carcinoma, Lewis Lun | 2002 |
Acetazolamide inhibits aquaporin-1 protein expression and angiogenesis.
Topics: Acetazolamide; Angiogenesis Inhibitors; Animals; Aquaporin 1; Aquaporins; Blood Group Antigens; Capi | 2004 |
The protein profile of acetazolamide-treated sera in mice bearing Lewis neoplasm.
Topics: Acetazolamide; Administration, Oral; Animals; Antineoplastic Agents; Blood Proteins; Carbonic Anhydr | 2004 |