acetazolamide has been researched along with Brain Injuries in 10 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetazolamide treatment improved the survival rate to 100% and decreased brain edema and AQP4 in ethanol-pretreated rats." | 1.38 | Expression of aquaporin-4 augments cytotoxic brain edema after traumatic brain injury during acute ethanol exposure. ( Honmou, O; Katada, R; Matsumoto, H; Mizuo, K; Nishitani, Y; Okazaki, S; Tateda, K; Watanabe, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cragoe, EJ | 1 |
| Gould, NP | 1 |
| Woltersdorf, OW | 1 |
| Ziegler, C | 1 |
| Bourke, RS | 1 |
| Nelson, LR | 1 |
| Kimelberg, HK | 1 |
| Waldman, JB | 1 |
| Popp, AJ | 1 |
| Sedransk, N | 1 |
| Shiogai, T | 1 |
| Koyama, M | 1 |
| Yamamoto, M | 1 |
| Hashimoto, H | 1 |
| Yoshikawa, K | 1 |
| Nakagawa, M | 1 |
| Katada, R | 1 |
| Nishitani, Y | 1 |
| Honmou, O | 1 |
| Mizuo, K | 1 |
| Okazaki, S | 1 |
| Tateda, K | 1 |
| Watanabe, S | 1 |
| Matsumoto, H | 1 |
| Harris, NG | 1 |
| Mironova, YA | 1 |
| Chen, SF | 1 |
| Richards, HK | 1 |
| Pickard, JD | 1 |
| TROTOT, R | 1 |
| Barkai, G | 1 |
| Goshen, E | 1 |
| Tzila Zwas, S | 1 |
| Dolberg, OT | 1 |
| Pick, CG | 1 |
| Bonne, O | 1 |
| Schreiber, S | 1 |
| Millet, A | 1 |
| Yonas, H | 1 |
| Pindzola, RP | 1 |
| Johnson, DW | 1 |
| Chang, CC | 1 |
| Kuwana, N | 1 |
| Ito, S | 1 |
| Ikegami, T | 1 |
| Bondoli, A | 1 |
| De Cosmo, G | 1 |
| Dordoni, L | 1 |
| Magalini, SI | 1 |
2 reviews available for acetazolamide and Brain Injuries
| Article | Year |
|---|---|
[Effect of osmotic diuretics, enzyme-inhibiting diuretics and neuroleptics on cerebral perfusion pressure].
Topics: Acetazolamide; Adrenal Cortex Hormones; Animals; Antipsychotic Agents; Brain Edema; Brain Injuries; | 1983 |
Xenon/computed tomography cerebral blood flow and its use in clinical management.
Topics: Acetazolamide; Brain Injuries; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation; Cerebrova | 1996 |
8 other studies available for acetazolamide and Brain Injuries
| Article | Year |
|---|---|
Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids.
Topics: Animals; Astrocytes; Bicarbonates; Brain Injuries; Carboxylic Acids; Cats; Cerebral Cortex; Chemical | 1982 |
Monitoring of brain tissue perfusion utilizing a transducer holder for transcranial color duplex sonography.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Brain; Brain Injuries; Carbonic Anhydrase Inhibitors; | 2013 |
Expression of aquaporin-4 augments cytotoxic brain edema after traumatic brain injury during acute ethanol exposure.
Topics: Acetazolamide; Animals; Aquaporin 4; Brain Edema; Brain Injuries; Carbonic Anhydrase Inhibitors; Eth | 2012 |
Preventing flow-metabolism uncoupling acutely reduces axonal injury after traumatic brain injury.
Topics: Acetazolamide; Animals; Brain Injuries; Cerebrovascular Circulation; Diffuse Axonal Injury; Energy M | 2012 |
[Remarks on the action of acetazolamide on certain closed cranial injuries].
Topics: Acetazolamide; Brain; Brain Injuries; Child; Infant; Skull; Skull Fractures | 1961 |
Acetazolamide-enhanced neuroSPECT scan reveals functional impairment after minimal traumatic brain injury not otherwise discernible.
Topics: Acetazolamide; Adult; Brain; Brain Injuries; Carbonic Anhydrase Inhibitors; Cognition Disorders; Hum | 2004 |
Impairment of cerebrovascular reactivity to acetazolamide in patients with normal pressure hydrocephalus.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Brain Injuries; Brain Neoplasms; Cerebrovascular Circ | 2000 |
[Acetazolamide in respiratory insufficiency].
Topics: Acetazolamide; Acid-Base Imbalance; Acute Disease; Brain Injuries; Chronic Disease; Humans; Hypercap | 1979 |