acetazolamide has been researched along with Brain Disorders in 21 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of the carbonic anhydrase inhibitor acetazolamide on intraocular pressure was studied in two patients with carbonic anhydrase II deficiency and in six control subjects." | 7.67 | Failure of acetazolamide to decrease intraocular pressure in patients with carbonic anhydrase II deficiency. ( Dodgson, SJ; Krupin, T; Sly, WS; Whyte, MP, 1985) |
| " Hyperhomocysteinemia is associated with blood-brain-barrier (BBB) disruption in brain disorders." | 4.12 | The Protective Effects of Acetazolamide Against Homocysteine-Induced Blood-Brain-Barrier Disruption by Regulating the Activation of the Wnt/β-Catenin Signaling Pathway. ( Li, C; Zhang, B, 2022) |
| "The effect of the carbonic anhydrase inhibitor acetazolamide on intraocular pressure was studied in two patients with carbonic anhydrase II deficiency and in six control subjects." | 3.67 | Failure of acetazolamide to decrease intraocular pressure in patients with carbonic anhydrase II deficiency. ( Dodgson, SJ; Krupin, T; Sly, WS; Whyte, MP, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (47.62) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Li, C | 1 |
| Zhang, B | 1 |
| Pramila, PJ | 1 |
| Mannam, P | 1 |
| Chacko, AG | 1 |
| Benjamin, RN | 1 |
| Pellegrino, F | 1 |
| Tardivo, I | 1 |
| Szatmári, S | 2 |
| Végh, T | 1 |
| Csomós, A | 1 |
| Hallay, J | 1 |
| Takács, I | 1 |
| Molnár, C | 2 |
| Fülesdi, B | 2 |
| Antek, C | 1 |
| Fülep, Z | 1 |
| Sárkány, P | 1 |
| Csiba, L | 1 |
| Yasui, M | 1 |
| PATEISKY, K | 2 |
| RINGEL, E | 2 |
| SWANSON, AG | 1 |
| MIZUNO, T | 1 |
| STARR, HJ | 1 |
| POSNER, JB | 1 |
| PLUM, F | 1 |
| Fu, JH | 1 |
| Lu, CZ | 1 |
| Hong, Z | 1 |
| Dong, Q | 1 |
| Ding, D | 1 |
| Wong, KS | 1 |
| Mathews, D | 1 |
| Walker, BS | 1 |
| Allen, BC | 1 |
| Batjer, H | 1 |
| Purdy, PD | 1 |
| Brauer, P | 1 |
| Kochs, E | 1 |
| Werner, C | 1 |
| Bloom, M | 1 |
| Policare, R | 1 |
| Pentheny, S | 1 |
| Yonas, H | 1 |
| Kofke, WA | 1 |
| Schulte am Esch, J | 1 |
| Oishi, M | 1 |
| Mochizuki, Y | 1 |
| Gotoh, F | 1 |
| Shinohara, Y | 1 |
| Bogsrud, TV | 1 |
| Rootwelt, K | 1 |
| Russell, D | 1 |
| Nyberg-Hansen, R | 1 |
| Weisinger, JR | 1 |
| Mogollón, A | 1 |
| Lander, R | 1 |
| Bellorin-Font, E | 1 |
| Riera, R | 1 |
| Abadí, I | 1 |
| Paz-Martínez, V | 1 |
| Krupin, T | 1 |
| Sly, WS | 1 |
| Whyte, MP | 1 |
| Dodgson, SJ | 1 |
| Di Cagno, L | 1 |
| Ravetto, A | 1 |
| Guidetti, B | 1 |
| Giuffrè, R | 1 |
| Gambacorta, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Serum Biomarkers in Sepsis Associated Encephalopathy (SAE)[NCT03133208] | 90 participants (Anticipated) | Observational | 2017-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for acetazolamide and Brain Disorders
| Article | Year |
|---|---|
Impaired cerebrovascular reactivity in sepsis-associated encephalopathy studied by acetazolamide test.
Topics: Acetazolamide; Anticonvulsants; Blood Flow Velocity; Brain Diseases; Cerebrovascular Circulation; Hu | 2010 |
Cerebral vasoreactivity to acetazolamide is not impaired in patients with severe sepsis.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Brain Diseases; Cerebrovascular | 2012 |
Correlation of transcranial Doppler sonography mean flow velocity with cerebral blood flow in patients with intracranial pathology.
Topics: Acetazolamide; Adolescent; Adult; Aged; Aged, 80 and over; Brain Diseases; Carbon Dioxide; Carbonic | 1998 |
18 other studies available for acetazolamide and Brain Disorders
| Article | Year |
|---|---|
The Protective Effects of Acetazolamide Against Homocysteine-Induced Blood-Brain-Barrier Disruption by Regulating the Activation of the Wnt/β-Catenin Signaling Pathway.
Topics: Acetazolamide; Animals; beta Catenin; Blood-Brain Barrier; Brain Diseases; Carbonic Anhydrase Inhibi | 2022 |
Progressive midbrain clefts after head trauma and decompressive surgery: a report of two patients.
Topics: Acetazolamide; Ataxia; Blepharoptosis; Brain Diseases; Brain Injuries, Diffuse; Carbonic Anhydrase I | 2021 |
SLC13A5-related epileptic encephalopathy successfully treated with valproate and acetazolamide.
Topics: Acetazolamide; Brain Diseases; Epilepsy, Generalized; Humans; Symporters; Valproic Acid | 2021 |
[Role of aquaporin, water channel in the brain].
Topics: Acetazolamide; Anesthetics, General; Animals; Aquaporin 4; Brain; Brain Diseases; Drug Design; Human | 2012 |
[Treatment of brain edema after attempted hanging].
Topics: Acetazolamide; Asphyxia; Brain; Brain Diseases; Brain Edema; Humans; Neck Injuries; Suicide | 1956 |
[Treatment of brain edema after attempted hanging].
Topics: Acetazolamide; Asphyxia; Brain; Brain Diseases; Brain Edema; Humans; Neck Injuries; Suicide | 1956 |
[Treatment of brain edema after attempted hanging].
Topics: Acetazolamide; Asphyxia; Brain; Brain Diseases; Brain Edema; Humans; Neck Injuries; Suicide | 1956 |
[Treatment of brain edema after attempted hanging].
Topics: Acetazolamide; Asphyxia; Brain; Brain Diseases; Brain Edema; Humans; Neck Injuries; Suicide | 1956 |
Effect of acetazoleamide (diamox) on encephalopathy induced by water excess and hypernatremia.
Topics: Acetazolamide; Brain; Brain Diseases; Humans; Hypernatremia; Water; Water-Electrolyte Balance | 1960 |
[DIAGNOSIS AND THERAPY OF CONVULSIVE DISEASES IN CHILDHOOD].
Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Amino Acids; Barbiturates; Brain Diseases; C | 1964 |
PSEUDOTUMOR CEREBRI. REPORT OF SIX CASES COMPARED WITH ONE CASE OF PSEUDOPAPILLEDEMA.
Topics: Acetazolamide; Brain Diseases; Brain Neoplasms; Chlorothiazide; Diagnosis; Diet, Sodium-Restricted; | 1964 |
The toxic effects of carbon dioxide and acetazolamide in hepatic encephalopathy.
Topics: Acetazolamide; Brain; Brain Diseases; Carbon Dioxide; Hepatic Encephalopathy; Humans; Liver Diseases | 1960 |
Relationship between cerebral vasomotor reactivity and white matter lesions in elderly subjects without large artery occlusive disease.
Topics: Acetazolamide; Aged; Blood Flow Velocity; Brain Diseases; Carotid Stenosis; Cerebrovascular Circulat | 2006 |
Diagnostic applications of simultaneously acquired dual-isotope single-photon emission CT scans.
Topics: Acetazolamide; Adolescent; Adult; Aged; Amphetamines; Brain; Brain Diseases; Cerebrovascular Disorde | 1994 |
Differences in regional cerebral blood flow in two types of leuko-araiosis.
Topics: Acetazolamide; Aged; Brain; Brain Diseases; Cerebral Cortex; Cerebral Ventriculography; Cerebrovascu | 1999 |
Role of carbonic anhydrase in chemical control and autoregulation of cerebral circulation.
Topics: Acetazolamide; Adult; Aged; Brain Diseases; Carbon Dioxide; Carbonic Anhydrases; Cerebrovascular Cir | 1977 |
Acetazolamide effect on cerebellar blood flow in crossed cerebral-cerebellar diaschisis.
Topics: Acetazolamide; Adult; Aged; Brain Diseases; Cerebellar Diseases; Cerebellum; Cerebral Arteries; Fema | 1990 |
Massive cerebral calcifications associated with increased renal phosphate reabsorption.
Topics: Absorption; Acetazolamide; Adolescent; Brain Diseases; Calcinosis; Calcium; Cerebral Cortex; Edetic | 1986 |
Failure of acetazolamide to decrease intraocular pressure in patients with carbonic anhydrase II deficiency.
Topics: Acetazolamide; Acidosis, Renal Tubular; Adult; Brain Diseases; Calcinosis; Carbonic Anhydrases; Fema | 1985 |
[Remote sequels of hypsarhythmic encephalopathy].
Topics: Acetazolamide; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Barbiturates; Brain Diseases; C | 1966 |
Follow-up study of 100 cases of pseudotumor cerebri.
Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Brain Diseases; Child; Child, P | 1968 |