Page last updated: 2024-10-22

acetazolamide and Bilateral Headache

acetazolamide has been researched along with Bilateral Headache in 114 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
" Currently, no standardized treatment guidelines are available and the current management focuses on weight loss and acetazolamide use."9.41Should topiramate be initial therapy in the management of idiopathic intracranial hypertension?: A literature review. ( Goyal, A; Zarroli, K, 2023)
"Crohn disease may present with pseudotumor cerebri and severe ocular perfusion deficits that are reversible with oral acetazolamide therapy."7.71Effect of acetazolamide on ocular hemodynamics in pseudotumor cerebri associated with inflammatory bowel disease. ( Arnaud, B; Greenfield, DS; Harris, A; Pageaux, GP; Veyrac, M; Villain, MA, 2002)
"In 43 persons with increased intraocular pressure (IOP) Timolol maleate eye drops (0."7.66Timolol. Hypotensive effect, used alone and in combination for treatment of increased intraocular pressure. ( Nielsen, NV, 1978)
"Ibuprofen was similar to acetazolamide in preventing symptoms of AMS, an interesting finding that implies a potentially new approach to prevention of cerebral forms of acute altitude illness."6.75Prospective, double-blind, randomized, placebo-controlled comparison of acetazolamide versus ibuprofen for prophylaxis against high altitude headache: the Headache Evaluation at Altitude Trial (HEAT). ( Allison, E; Basnyat, B; Fisher, RS; Gertsch, JH; Hanzelka, K; Hazan, A; Holck, PS; Lipman, GS; Merritt, A; Meyers, Z; Mulcahy, A; Odegaard, J; Pook, B; Slomovic, B; Thompson, M; Wahlberg, H; Weiss, EA; Wilshaw, V; Zafren, K, 2010)
" Currently, no standardized treatment guidelines are available and the current management focuses on weight loss and acetazolamide use."5.41Should topiramate be initial therapy in the management of idiopathic intracranial hypertension?: A literature review. ( Goyal, A; Zarroli, K, 2023)
"Patients with untreated IIH and mild vision loss enrolled in the IIHTT and randomized to acetazolamide (ACZ) and weight loss or placebo (PLB) and weight loss had prospective assessment of headache disability using the Headache Impact Test-6 (HIT-6) questionnaire."5.24Headache in Idiopathic Intracranial Hypertension: Findings From the Idiopathic Intracranial Hypertension Treatment Trial. ( Friedman, DI; Gao, S; McDermott, M; Mejico, LJ; Quiros, PA; Subramanian, PS; Wall, M, 2017)
" The Idiopathic Intracranial Hypertension Treatment Trial was an adult, multicenter study that examined the use of acetazolamide and weight loss on the course of PIH."5.12Pediatric Intracranial Hypertension: A Spotlight on Imaging, the Idiopathic Intracranial Hypertension Treatment Trial, and COVID-19 Associated Cases. ( Aylward, SC; Brun, BN, 2021)
"We conducted a trial of oral acetazolamide for the treatment of cryptococcal meningitis in 22 Thai adults with headache and an opening cerebrospinal fluid pressure of >/=200 mm H(2)0."5.10A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis. ( Chasombat, S; Chierakul, W; Lalloo, DG; Maek-A-Nantawat, W; Newton, PN; Phonrat, B; Pitisuttithum, P; Rajanuwong, A; Short, JM; Teaunadi, R; Thai, le H; Tip, NQ; White, NJ, 2002)
" Both completed trials compared acetazolamide to placebo, in conjunction with a weight loss intervention in both groups."4.91Interventions for idiopathic intracranial hypertension. ( Fouyas, IP; Hughes, MA; Jamjoom, AA; Kalyvas, AV; Piper, RJ; Young, AM, 2015)
"This open-label, single-center pilot study suggests that GLP-1-RAs are an effective and safe treatment option for achieving significant weight loss with a favorable effect on headache, leading to reduced acetazolamide dosage in pwIIH."4.31Treatment with GLP-1 receptor agonists is associated with significant weight loss and favorable headache outcomes in idiopathic intracranial hypertension. ( Bsteh, G; Harreiter, J; Itariu, B; Krajnc, N; Macher, S; Marik, W; Michl, M; Novak, K; Pemp, B; Wöber, C, 2023)
"VSS is an effective and safe procedure resulting in significant improvement of headaches, visual impairment, dizziness, and tinnitus, acetazolamide and topiramate usage were lower after VSS in patients with IIH."4.12Dural Venous Sinus Stenting in Idiopathic Intracranial Hypertension: A National Database Study of 541 Patients. ( Kan, P; Lall, R; Nia, AM; Srinivasan, VM, 2022)
" The most common symptom was headache (69%) and acetazolamide was the most used medication (69%)."3.88Pseudotumor cerebri in childhood and adolescence: data from a specialized service. ( Balbi, GGM; Fraga, MM; Len, CA; Matas, SL; Sousa, IO; Terreri, MT, 2018)
"Crohn disease may present with pseudotumor cerebri and severe ocular perfusion deficits that are reversible with oral acetazolamide therapy."3.71Effect of acetazolamide on ocular hemodynamics in pseudotumor cerebri associated with inflammatory bowel disease. ( Arnaud, B; Greenfield, DS; Harris, A; Pageaux, GP; Veyrac, M; Villain, MA, 2002)
"Idiopathic intracranial hypertension (IIH, pseudotumor cerebri) was diagnosed in 4 patients who had been treated with tetracycline."3.69[Idiopathic intracranial hypertension and tetracycline]. ( Schwartz, M; Sharf, B; Sierpinski-Barth, J; Weller, B, 1994)
"In 43 persons with increased intraocular pressure (IOP) Timolol maleate eye drops (0."3.66Timolol. Hypotensive effect, used alone and in combination for treatment of increased intraocular pressure. ( Nielsen, NV, 1978)
"Acetazolamide was more effective than spironolactone in preventing AMS (OR = 0."2.76Spironolactone does not prevent acute mountain sickness: a prospective, double-blind, randomized, placebo-controlled trial by SPACE Trial Group (spironolactone and acetazolamide trial in the prevention of acute mountain sickness group). ( Alexander, HD; Basnyat, B; Farrar, J; Gertsch, J; Halverson, S; Holck, PS; Joshi, A; Karambay, J; Khanal, S; Morrissey, C; Powell, S; Pun, M; Shankar, R; Steif, M; Stone, A; Szawarski, P; Thompson, BH, 2011)
"Ibuprofen was similar to acetazolamide in preventing symptoms of AMS, an interesting finding that implies a potentially new approach to prevention of cerebral forms of acute altitude illness."2.75Prospective, double-blind, randomized, placebo-controlled comparison of acetazolamide versus ibuprofen for prophylaxis against high altitude headache: the Headache Evaluation at Altitude Trial (HEAT). ( Allison, E; Basnyat, B; Fisher, RS; Gertsch, JH; Hanzelka, K; Hazan, A; Holck, PS; Lipman, GS; Merritt, A; Meyers, Z; Mulcahy, A; Odegaard, J; Pook, B; Slomovic, B; Thompson, M; Wahlberg, H; Weiss, EA; Wilshaw, V; Zafren, K, 2010)
"Parents of school-age children with idiopathic intracranial hypertension were asked to fill out a questionnaire and to rank the child's behavioral patterns before and after the diagnosis and treatment of the disease."2.73Behavioral disorders in children with idiopathic intracranial hypertension. ( Leiba, H; Margalit, D; Parness-Yossifon, R; Pollack, A, 2008)
"The accurate diagnosis of idiopathic intracranial hypertension is essential as visual deterioration due to papilledema may be irreversible."2.72Diagnosis and treatment of idiopathic intracranial hypertension. ( Hoffmann, J; Raoof, N, 2021)
" A comparison of a difference in decline in average AMS score over time showed a statistically significant decline for the 250-mg dosing group versus placebo (p = 0."2.71A dose-response study of acetazolamide for acute mountain sickness prophylaxis in vacationing tourists at 12,000 feet (3630 m). ( Carlsten, C; Ruoss, S; Swenson, ER, 2004)
"Symptomatic treatment of headache is recommended."2.61[Idiopathic intracranial hypertension - Swedish consensus guidelines]. ( Gustavsson, B; Hellgren, K; Lundvall, M; Nilsson Remahl, I; Söderman, M; Sundholm, A; Träisk, F, 2019)
"Idiopathic intracranial hypertension is characterized by signs and symptoms of raised intracranial pressure with no established pathogenesis."2.55[Idiopathic intracranial hypertension]. ( Bäuerle, J; Egger, K; Harloff, A, 2017)
"The term idiopathic intracranial hypertension (pseudotumor cerebri) describes an increase in CSF pressure without a space-occupying intracranial lesion or hydrocephalus."2.48[Headache from increased cerebrospinal fluid pressure]. ( Göbel, C; Göbel, H; Heinze, A, 2012)
"Headache was observed in 42 cases pre-DDZ, and post-DDZ there was a 71% reduction in headache (P < 0."1.62Decadron, Diamox, and Zantac: A Novel Combination for Ventricular Shunt Failure in Pediatric Neurosurgical Patients. ( Abend, NS; Atkin, NJ; Heuer, G; Huh, JW; Kanuga, BM; Kirschen, MP; Lang, SS; Li, Y; Ploof, J; Storm, PB; Topjian, AA; Tran-Du, K; Waanders, AJ; Yuan, I; Zorc, JJ, 2021)
"Idiopathic intracranial hypertension is a diagnosis of exclusion and imaging studies should always be performed to rule out other structural and obstructive lesions."1.51Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report. ( Berry, B; Ghannam, M; Ghazaleh, D; Samara, A, 2019)
"Intracranial hypertension is rare in children and commonly seen in overweight females older than 12 years similar to adults."1.51Pediatric intracranial hypertension. Experience from 2 Tertiary Centers. ( Ajlan, AM; Al Abdulsalam, HK; Al Twaijri, WA; Al-Showaeir, DA; Albakr, AA; Aldabjan, HM; Aldegether, MS; Alhothali, WM; Almalki, FI; Altweijri, IS; Alwadei, AH; Bashiri, FA; Hamad, MH; Hassan, HH; Hassan, SM; Kentab, AY; Salih, MA, 2019)
"Purpose/Aim: Pseudotumor cerebri or idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure of unknown etiology."1.46A case series of dural venous sinus stenting in idiopathic intracranial hypertension: association of outcomes with optical coherence tomography. ( Abraham, MG; Arnold, PM; Camarata, PJ; Peterson, JC; Smith, KA; Whittaker, TJ, 2017)
"Acetazolamide was effective in reducing both the frequency and severity of vertigo and headache attacks and this effect was more prominent for vertigo frequency and severity."1.43Acetazolamide in vestibular migraine prophylaxis: a retrospective study. ( Bilgen, C; Çelebisoy, N; Gökçay, F; Karahan, C; Karapolat, H; Kirazlı, T; Köse, T, 2016)
"The patient who suffered the recurrence presented an exhausted CRC and the collateral circulation was less favourable in the symptomatic hemisphere."1.40[Bilateral carotid artery occlusion: prognosis and neurosonological features]. ( Díaz-Otero, F; Fernández-Bullido, Y; García-Pastor, A; Gil-Núñez, A; Pérez-Sánchez, JR; Rodríguez-Cruz, PM; Sobrino-García, P; Vázquez-Alén, P; Vicente-Peracho, G; Villanueva-Osorio, JA, 2014)
"The patient was diagnosed with idiopathic intracranial hypertension and treated with azetazolamide."1.39[Idiopathic intracranial hypertension is a rare cause of headache in children]. ( Hansen, JK; Møller, HU; Viuff, AC, 2013)
"Acetazolamide was used as the first drug and was effective in only 4 patients who had no underlying cause."1.38Pseudotumour cerebri in children: etiological, clinical features and treatment modalities. ( Hacifazlioglu Eldes, N; Yilmaz, Y, 2012)
"Treatment with acetazolamide reduced the cerebrospinal pressure."1.35[Idiopathic intracranial hypertension without headache detected during a routine health check]. ( Niino, M; Sakushima, K; Sasaki, H; Tsuji, S; Yabe, I, 2008)
"Acute angle closure glaucoma is an ocular emergency that is treatable with prompt and appropriate intervention."1.33An uncommon presentation of acute angle closure glaucoma. ( Berkoff, DJ; Sanchez, LD, 2005)
"However, prompt diagnosis of idiopathic intracranial hypertension and initiation of medical therapy lead to improved symptoms and restored vision."1.33Idiopathic intracranial hypertension and sickle cell disease: two case reports. ( Discepola, M; Segal, L, 2005)
"Cover test revealed an intermittent esotropia at distance, with full ocular motilities."1.31Pseudotumor cerebri in a pre-pubescent child--case report. ( Langford, CM, 2002)
"Idiopathic "benign" intracranial hypertension is an uncommon but important cause of headache that can lead to visual loss."1.31Idiopathic "benign" intracranial hypertension: case series and review. ( Kirkham, FJ; MacGregor, DL; Salman, MS, 2001)
"Presenting symptoms of idiopathic intracranial hypertension are known to vary with age."1.31Asymptomatic idiopathic intracranial hypertension in young children. ( Weig, SG, 2002)
"Chronic daily headaches are frequently associated with rebound headaches after ergotamine, barbiturate, caffeine, and analgesic abuse."1.30Transformed migraine is a cause of chronic daily headaches. ( Haque, A; Konno, S; Margishvili, GM; Meyer, JS; Rauch, RA, 1999)
"Pseudotumor cerebri is a clinical syndrome characterized by increased intracranial pressure in the absence of an intracranial tumor."1.30Pseudotumor cerebri as a presenting symptom of acute sinusitis in a child. ( Keren, T; Lahat, E, 1998)
"Although rare, Wegener's granulomatosis should be included in the differential diagnosis of chronic aseptic meningitis, communicating hydrocephalus, and papilledema."1.30Communicating hydrocephalus secondary to diffuse meningeal spread of Wegener's granulomatosis: case report and literature review. ( Medsger, TA; Scarrow, AM; Segal, R; Wasko, MC, 1998)
"We report two cases of idiopathic intracranial hypertension causing chronic daily headache with migrainous features in the absence of associated papilledema."1.29Chronic daily headache with migrainous features due to papilledema-negative idiopathic intracranial hypertension. ( Huff, AL; Hupp, SL; Rothrock, JF, 1996)
"In previous accounts of idiopathic intracranial hypertension in children, concomitant papilledema, visual symptoms and/or palsy of the sixth cranial nerve are described."1.29Idiopathic intracranial hypertension in a young child without visual symptoms or signs. ( Bello, L; Winner, P, 1996)
"A review of the most recent 23 cases of benign intracranial hypertension (BIH), admitted to the War Memorial Children's Hospital in London, Ontario, provided a compendium of the clinical manifestations of this disorder in children and adolescents."1.27Spectrum of benign intracranial hypertension in children and adolescents. ( Amacher, AL; Spence, JD, 1985)

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-199011 (9.65)18.7374
1990's15 (13.16)18.2507
2000's31 (27.19)29.6817
2010's43 (37.72)24.3611
2020's14 (12.28)2.80

Authors

AuthorsStudies
Brun, BN1
Aylward, SC1
Trenz, ME1
Zakin, E1
Nia, AM1
Srinivasan, VM1
Lall, R1
Kan, P1
Souza, MNP1
Costa, BAL1
Santos, FRDR1
Fortini, I1
Alqahtani, Y1
Oshi, M1
Kamal, NM1
Aljabri, M1
Abosabie, S1
Elhaj, W1
Abosabie, SA1
Krajnc, N1
Itariu, B1
Macher, S1
Marik, W1
Harreiter, J1
Michl, M1
Novak, K1
Wöber, C1
Pemp, B1
Bsteh, G1
Goyal, A1
Zarroli, K1
Bashiri, FA1
Al Abdulsalam, HK1
Hassan, SM1
Al Twaijri, WA1
Almalki, FI1
Kentab, AY1
Hamad, MH1
Alwadei, AH1
Al-Showaeir, DA1
Altweijri, IS1
Aldabjan, HM1
Aldegether, MS1
Albakr, AA1
Alhothali, WM1
Ajlan, AM1
Hassan, HH1
Salih, MA1
Ybarra, M1
Santos, TJD1
Queiroz, ES1
Rachid, L1
Franco, RR1
Cominato, L1
Moura, FC1
Velhote, MC1
Damiani, D1
Lang, SS1
Ploof, J1
Atkin, NJ1
Tran-Du, K1
Kanuga, BM1
Storm, PB1
Heuer, G1
Yuan, I1
Abend, NS1
Kirschen, MP1
Topjian, AA1
Li, Y1
Waanders, AJ1
Zorc, JJ1
Huh, JW1
Togha, M1
Martami, F1
Rahmanzadeh, R1
Ghorbani, Z1
Refaeian, F1
Behbahani, S1
Panahi, P1
Moghadam, NB1
Nafissi, S1
Shahbazi, M1
Daou, BJ1
Sweid, A1
Weinberg, JH1
Starke, RM1
Sergott, RC1
Doermann, AS1
Hauge, J1
Zanaty, M1
Chalouhi, N1
Gooch, R1
Herial, N1
Zarzour, H1
Jabbour, P1
Rosenwasser, RH1
Tjoumakaris, S1
Alboudi, A1
Johnson, EC1
Namiki, H1
Raoof, N1
Hoffmann, J1
Subedi, Y1
Friedman, DI1
Quiros, PA1
Subramanian, PS1
Mejico, LJ1
Gao, S1
McDermott, M1
Wall, M1
Fernández-García, MÁ1
Cantarín-Extremera, V1
Andión-Catalán, M1
Duat-Rodríguez, A1
Jiménez-Echevarría, S1
Bermejo-Arnedo, I1
Hortigüela-Saeta, M1
Rekarte-García, S1
Babín-López, L1
Ruano Domínguez, D1
Balbi, GGM1
Matas, SL1
Len, CA1
Fraga, MM1
Sousa, IO1
Terreri, MT1
Chia, XX1
Cordato, D1
Venkat, A1
Spicer, ST1
Samara, A1
Ghazaleh, D1
Berry, B1
Ghannam, M1
Sundholm, A1
Träisk, F1
Hellgren, K1
Lundvall, M1
Söderman, M1
Gustavsson, B1
Nilsson Remahl, I1
Viuff, AC1
Hansen, JK1
Møller, HU1
He, MS1
Sheu, MM1
Huang, ZL1
Tsai, CH1
Tsai, RK1
Aragonès, JM1
Alonso-Valdés, F1
Ohringer, G1
Burke, T1
Shaikh, A1
Arngrim, N1
Schytz, HW1
Asghar, MS2
Amin, FM1
Hougaard, A1
Larsen, VA1
de Koning, PJH1
Larsson, HBW1
Olesen, J1
Ashina, M1
D'Amico, D1
Curone, M1
Erbetta, A1
Farago', G1
Bianchi-Marzoli, S1
Ciasca, P1
Bussone, G1
Chiapparini, L1
Pérez-Sánchez, JR1
García-Pastor, A1
Díaz-Otero, F1
Sobrino-García, P1
Rodríguez-Cruz, PM1
Vicente-Peracho, G1
Vázquez-Alén, P1
Fernández-Bullido, Y1
Villanueva-Osorio, JA1
Gil-Núñez, A1
Sun, LW1
Horton, JC1
Butori, P1
Jean-Charles, A1
Elana, G1
Merle, H1
Piper, RJ1
Kalyvas, AV1
Young, AM1
Hughes, MA1
Jamjoom, AA1
Fouyas, IP1
Kumar, S1
Srivastava, T1
Tejwani, S1
Khilnani, K1
Çelebisoy, N1
Gökçay, F1
Karahan, C1
Bilgen, C1
Kirazlı, T1
Karapolat, H1
Köse, T1
Rivero-Sanz, E1
Pias-Peleteiro, L1
Gonzalez-Alvarez, V1
Smith, KA1
Peterson, JC1
Arnold, PM1
Camarata, PJ1
Whittaker, TJ1
Abraham, MG1
Kwon, YJ1
Allen, JL1
Liu, GT1
McCormack, SE1
Tibussek, D1
Distelmaier, F1
Karenfort, M1
Harmsen, S1
Klee, D1
Mayatepek, E1
Bäuerle, J1
Egger, K1
Harloff, A1
Scott, NL1
Stryjewski, TP1
Rizzo, JF2
Marton, E1
Feletti, A1
Mazzucco, GM1
Longatti, P1
Kuzman, MR1
Jovanovic, N1
Vukelja, D1
Medved, V1
Hotujac, L1
Sakushima, K1
Tsuji, S1
Niino, M1
Yabe, I1
Sasaki, H1
van Patot, MC1
Leadbetter, G1
Keyes, LE1
Maakestad, KM1
Olson, S1
Hackett, PH2
Basnyat, B5
Gertsch, JH3
Holck, PC1
Parentin, F1
Marchetti, F1
Faleschini, E1
Tonini, G1
Pensiero, S1
Lamirel, C1
Bruce, BB1
Newman, N1
Biousse, V1
Lipman, GS1
Holck, PS2
Merritt, A1
Mulcahy, A1
Fisher, RS1
Allison, E1
Hanzelka, K1
Hazan, A1
Meyers, Z1
Odegaard, J1
Pook, B1
Thompson, M1
Slomovic, B1
Wahlberg, H1
Wilshaw, V1
Weiss, EA1
Zafren, K1
Geara, AS1
El-Imad, B1
El-Sayegh, S1
Pun, M2
Halverson, S1
Szawarski, P1
Gertsch, J1
Steif, M1
Powell, S1
Khanal, S1
Joshi, A1
Shankar, R1
Karambay, J1
Alexander, HD1
Stone, A1
Morrissey, C1
Thompson, BH1
Farrar, J1
Julian, CG1
Subudhi, AW1
Wilson, MJ1
Dimmen, AC1
Pecha, T1
Roach, RC2
Hacifazlioglu Eldes, N1
Yilmaz, Y1
Richalet, JP1
Larmignat, P1
Poitrine, E1
Letournel, M1
Canouï-Poitrine, F1
Dolinsky, DH1
Armstrong, S1
Skone, K1
Abbott, J1
Wacogne, ID1
Williams, MW1
Vishwanath, M1
Lalla, R1
Malhotra, HS1
Garg, RK1
Verma, R1
Göbel, H1
Göbel, C1
Heinze, A1
Brun, A1
Julier, I1
Sirvain, S1
Fraisse, T1
Lawley, JS1
Oliver, SJ1
Mullins, P1
Morris, D1
Junglee, NA1
Jelleyman, C1
Macdonald, JH1
Galveia, JN1
Mendonça, AP1
Costa, JM1
Victorio, MC1
Rothner, AD1
Wraige, E1
Chandler, C1
Pohl, KR1
Newton, PN1
Thai, le H1
Tip, NQ1
Short, JM1
Chierakul, W1
Rajanuwong, A1
Pitisuttithum, P1
Chasombat, S1
Phonrat, B1
Maek-A-Nantawat, W1
Teaunadi, R1
Lalloo, DG1
White, NJ1
Villain, MA1
Pageaux, GP1
Veyrac, M1
Arnaud, B1
Harris, A1
Greenfield, DS1
Morrison, DG1
Phuah, HK1
Reddy, AT1
Dure, LS1
Kline, LB1
Langford, CM1
Sastry, J1
Karandikar, SS1
English, MW1
Johnson, EW1
Castro-Marin, F1
Inoue, Y1
Yeh, C1
Bassuk, AG1
Burrowes, DM1
Velimirovic, B1
Grant, J1
Keating, GF1
CHIERI, S1
MAFFEO, G1
Cestari, DM1
Carlsten, C1
Swenson, ER1
Ruoss, S1
Lane, M1
McBride, J1
Archer, J1
Konno, S1
Meyer, JS1
Margishvili, GM1
Rauch, RA1
Haque, A1
Ganguly, S1
Berkoff, DJ1
Sanchez, LD1
Segal, L1
Discepola, M1
Martín Rodríguez, MM1
Ruiz-Cabello Jiménez, M1
Gómez García, M1
Vega Villaamil, P1
González Castillo, S1
Kayser, B1
Hulsebosch, R1
Bosch, F1
Parness-Yossifon, R1
Margalit, D1
Pollack, A1
Leiba, H1
Mountain, RD1
Wandstrat, TL1
Phillips, J1
Weller, B1
Sharf, B1
Sierpinski-Barth, J1
Schwartz, M1
Torrance, RW1
Selky, AK1
Dobyns, WB1
Yee, RD1
Hanson, L1
Morgan, HJ1
Mathew, NT1
Ravishankar, K1
Sanin, LC1
Huff, AL1
Hupp, SL1
Rothrock, JF1
Winner, P1
Bello, L1
Krishna, R1
Kosmorsky, GS1
Wright, KW1
Mishriki, YY1
Keren, T1
Lahat, E1
Scarrow, AM1
Segal, R1
Medsger, TA1
Wasko, MC1
Wang, SJ1
Fuh, JL1
Lu, SR1
Halevy, A1
Offer, I1
Garty, B1
Chalaupka, FD1
Venkatesha, SL1
Umamaheswara Rao, GS1
Salman, MS1
Kirkham, FJ1
MacGregor, DL1
Weig, SG1
Nielsen, NV1
Tarr, RW1
Johnson, DW1
Rutigliano, M1
Hecht, ST1
Pentheny, S1
Jungreis, CA1
Horton, JA1
Yonas, H1
Simonsen, L1
Steinmetz, H1
Sjøgren, P1
Amacher, AL1
Spence, JD1
Carver, RP1
Winsmann, FR1
Wilson, R1
Forwand, SA1
Landowne, M1
Follansbee, JN1
Hansen, JE1
Appenzeller, O1
Gray, GW1
Sinclair, D1
Bryan, AC1
Houston, CS1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neurocognitive Outcome in Children Who Suffered From Idiopathic Increased Intracranial Hypertension (IIH)[NCT02857335]15 participants (Actual)Interventional2016-01-31Active, not recruiting
Sickness Evaluation at Altitude With Acetazolamide at Relative Doses[NCT03828474]Phase 1108 participants (Actual)Interventional2019-08-09Completed
Acute Mountain Sickness Treatment: A Double-blind Comparison of Metoclopramide vs. Ibuprofen[NCT01522326]300 participants (Anticipated)Interventional2012-03-01Completed
Controlled Hyperventilation as Prophylaxis for Acute Mountain Sickness: A Randomized Controlled Trial[NCT02972411]30 participants (Anticipated)Interventional2016-10-31Recruiting
Study of Periodic Breathing in Healthy Humans[NCT02201875]120 participants (Anticipated)Observational2014-09-30Not yet recruiting
Calibration of a New Reflectance Oximeter.[NCT02842255]10 participants (Actual)Interventional2015-10-31Completed
Multicentric Evaluation of the Impact on Hypoxia Sensitivity of Patients With COVID-19[NCT05167357]90 participants (Anticipated)Interventional2021-03-18Recruiting
Intracranial Pressure in Experimental Models of Headache[NCT01288781]23 participants (Actual)Interventional2011-07-31Completed
Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.[NCT01519544]34 participants (Actual)Interventional2012-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Blood Oxygen Saturation

Baseline is defined as the average of the 3 hour and 12 hour normoxia measurement. 24 hours is defined at the 24 hour hypoxia measurement. (NCT01288781)
Timeframe: Blood Oxygen Saturation: baseline, 24 hours.

Intervention% oxygen saturation (Mean)
Acetazolamide10.8
Placebo11.1

Change in Fluid Balance

"Baseline is defined as the average of the 3 hour and 12 hour normoxia measurement. 24 hours is defined at the 24 hour hypoxia measurement. Urine output was recorded by 24 hour urine collection and fluid intake by 24 hour food diaries. Fluid balance was calculated as:~(urine output (L) / fluid intake (L) ) * 100." (NCT01288781)
Timeframe: Fluid Balance: baseline, 24 hours.

Intervention% of fluid intake (Mean)
Acetazolamide342
Placebo147

Change in High Altitude Headache by Visual Analogue Scale

Baseline is defined as the average of the 3 hour and 12 hour normoxia measurement. 24 hours is defined at the 24 hour hypoxia measurement. Outcome measured using visual analogue scale, where 0 mm is no headache and 100 mm is maximum headache. (NCT01288781)
Timeframe: High Altitude Headache: baseline, 24 hours.

Interventionmm (Mean)
Acetazolamide6.4
Placebo7.2

Change in Optic Nerve Sheath Diameter

Baseline is defined as the average of the 3 hour 12 hour normoxia measurements. 12 hours is defined at the 12 hour hypoxia measurement. (NCT01288781)
Timeframe: Optic Nerve Sheath Diameter: baseline, 12 hours.

Interventionmm (Mean)
Acetazolamide0.01
Placebo0.01

Change in Optic Nerve Sheath Diameter

Baseline is defined as the average of the 3 hour 12 hour normoxia measurements. 3 hours is defined at the 3 hour hypoxia measurement. (NCT01288781)
Timeframe: Optic Nerve Sheath Diameter: baseline, 3 hours.

Interventionmm (Mean)
Acetazolamide0.00
Placebo-0.01

Change in Optic Nerve Sheath Diameter

Baseline is defined as the average of the 3 hour and 12 hour normoxia measurements. 36 hours is defined at the 36 hour hypoxia measurement. (NCT01288781)
Timeframe: Optic Nerve Sheath Diameter: baseline, 36 hours.

Interventionmm (Mean)
Acetazolamide0.01
Placebo0.00

Change in Optic Nerve Sheath Diameter by Ultrasonography

"Baseline is defined as the average of the 3 hour and 12 hour normoxia measurement.~24 hours is defined at the 24 hour hypoxia measurement. Optic nerve sheath diameter obtained by ultrasonography of the eye. Increased optic nerve sheath diameter suggests greater intra cranial pressure." (NCT01288781)
Timeframe: Optic Nerve Sheath Diameter: baseline, 24 hours.

Interventionmm (Mean)
Acetazolamide0.02
Placebo0.02

Reviews

14 reviews available for acetazolamide and Bilateral Headache

ArticleYear
Pediatric Intracranial Hypertension: A Spotlight on Imaging, the Idiopathic Intracranial Hypertension Treatment Trial, and COVID-19 Associated Cases.
    Seminars in pediatric neurology, 2021, Volume: 40

    Topics: Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Child; Combined Modality Therapy; C

2021
Update on Idiopathic Intracranial Hypertension Management.
    Arquivos de neuro-psiquiatria, 2022, Volume: 80, Issue:5 Suppl 1

    Topics: Acetazolamide; Headache; Humans; Intracranial Hypertension; Obesity; Pseudotumor Cerebri; Vision Dis

2022
Should topiramate be initial therapy in the management of idiopathic intracranial hypertension?: A literature review.
    Medicine, 2023, Oct-20, Volume: 102, Issue:42

    Topics: Acetazolamide; Female; Headache; Humans; Intracranial Hypertension; Intracranial Pressure; Pseudotum

2023
Diagnosis and treatment of idiopathic intracranial hypertension.
    Cephalalgia : an international journal of headache, 2021, Volume: 41, Issue:4

    Topics: Acetazolamide; Analgesics; Headache; Headache Disorders; Humans; Intracranial Hypertension; Migraine

2021
[Idiopathic intracranial hypertension - Swedish consensus guidelines].
    Lakartidningen, 2019, May-15, Volume: 116

    Topics: Acetazolamide; Bariatric Surgery; Carbonic Anhydrase Inhibitors; Consensus; Critical Pathways; Diagn

2019
Interventions for idiopathic intracranial hypertension.
    The Cochrane database of systematic reviews, 2015, Aug-07, Issue:8

    Topics: Acetazolamide; Adult; Antihypertensive Agents; Cerebrospinal Fluid Pressure; Female; Headache; Human

2015
HaNDL syndrome in a 14-year-old girl.
    BMJ case reports, 2016, Jan-14, Volume: 2016

    Topics: Acetazolamide; Adolescent; Aphasia, Broca; Carbonic Anhydrase Inhibitors; Diagnosis, Differential; F

2016
[Idiopathic intracranial hypertension].
    Der Nervenarzt, 2017, Volume: 88, Issue:2

    Topics: Acetazolamide; Blindness; Combined Modality Therapy; Diagnosis, Differential; Diet Therapy; Evidence

2017
Effects of glyceryl trinitrate and calcitonin gene-related peptide on BOLD signal and arterial diameter: methodological studies by fMRI and MRA.
    Danish medical journal, 2012, Volume: 59, Issue:7

    Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Brain; Calcitonin Gene-Related Peptide; Cerebral

2012
[Headache from increased cerebrospinal fluid pressure].
    Schmerz (Berlin, Germany), 2012, Volume: 26, Issue:3

    Topics: Acetazolamide; Algorithms; Cerebrospinal Fluid Pressure; Cerebrospinal Fluid Shunts; Combined Modali

2012
Diagnosis and treatment of idiopathic intracranial hypertension (IIH) in children and adolescents.
    Current neurology and neuroscience reports, 2013, Volume: 13, Issue:3

    Topics: Acetazolamide; Adolescent; Cerebrospinal Fluid Shunts; Child; Diuretics; Headache; Humans; Intracran

2013
High altitude cerebral edema.
    High altitude medicine & biology, 2004,Summer, Volume: 5, Issue:2

    Topics: Acetazolamide; Adult; Altitude Sickness; Brain Edema; Carbonic Anhydrase Inhibitors; Child; Consciou

2004
Carbonic anhydrase near central chemoreceptors.
    Advances in experimental medicine and biology, 1993, Volume: 337

    Topics: Acetazolamide; Animals; Benzolamide; Capillaries; Carbonic Anhydrases; Cats; Chemoreceptor Cells; He

1993
Acute high-altitude illness in mountaineers and problems of rescue.
    Annals of internal medicine, 1973, Volume: 78, Issue:3

    Topics: Acclimatization; Acetazolamide; Acute Disease; Altitude; Brain Edema; Coma; Dexamethasone; Furosemid

1973

Trials

17 trials available for acetazolamide and Bilateral Headache

ArticleYear
Headache in Idiopathic Intracranial Hypertension: Findings From the Idiopathic Intracranial Hypertension Treatment Trial.
    Headache, 2017, Volume: 57, Issue:8

    Topics: Acetazolamide; Adolescent; Adult; Aged; Analgesics; Comorbidity; Disability Evaluation; Diuretics; F

2017
Association of acetazolamide infusion with headache and cranial artery dilation in healthy volunteers.
    Pain, 2014, Volume: 155, Issue:8

    Topics: Acetazolamide; Adult; Arteries; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation; Cross-Ov

2014
Prophylactic low-dose acetazolamide reduces the incidence and severity of acute mountain sickness.
    High altitude medicine & biology, 2008,Winter, Volume: 9, Issue:4

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Carbonic Anhydrase Inhibitors; Dose-Response

2008
Prospective, double-blind, randomized, placebo-controlled comparison of acetazolamide versus ibuprofen for prophylaxis against high altitude headache: the Headache Evaluation at Altitude Trial (HEAT).
    Wilderness & environmental medicine, 2010, Volume: 21, Issue:3

    Topics: Acetazolamide; Adolescent; Adult; Aged; Altitude Sickness; Anti-Inflammatory Agents, Non-Steroidal;

2010
Spironolactone does not prevent acute mountain sickness: a prospective, double-blind, randomized, placebo-controlled trial by SPACE Trial Group (spironolactone and acetazolamide trial in the prevention of acute mountain sickness group).
    Wilderness & environmental medicine, 2011, Volume: 22, Issue:1

    Topics: Acetazolamide; Adult; Altitude Sickness; Double-Blind Method; Female; Headache; Humans; Male; Mounta

2011
Acute mountain sickness, inflammation, and permeability: new insights from a blood biomarker study.
    Journal of applied physiology (Bethesda, Md. : 1985), 2011, Volume: 111, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude; Altitude Sickness; Anti-Inflammatory Agents; Biomarke

2011
Optic nerve sheath diameter is not related to high altitude headache: a randomized controlled trial.
    High altitude medicine & biology, 2012, Volume: 13, Issue:3

    Topics: Acclimatization; Acetazolamide; Adult; Altitude; Analysis of Variance; Diuretics; Double-Blind Metho

2012
A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Sep-15, Volume: 35, Issue:6

    Topics: Acetazolamide; Acidosis; Administration, Oral; Adult; Amphotericin B; Antifungal Agents; Diuretics;

2002
Efficacy of low-dose acetazolamide (125 mg BID) for the prophylaxis of acute mountain sickness: a prospective, double-blind, randomized, placebo-controlled trial.
    High altitude medicine & biology, 2003,Spring, Volume: 4, Issue:1

    Topics: Acetazolamide; Adolescent; Adult; Aged; Altitude Sickness; Carbonic Anhydrase Inhibitors; Dose-Respo

2003
A dose-response study of acetazolamide for acute mountain sickness prophylaxis in vacationing tourists at 12,000 feet (3630 m).
    High altitude medicine & biology, 2004,Spring, Volume: 5, Issue:1

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Bolivia; Carbonic Anhydrase Inhibitors; Dose

2004
Low-dose acetylsalicylic acid analog and acetazolamide for prevention of acute mountain sickness.
    High altitude medicine & biology, 2008,Spring, Volume: 9, Issue:1

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Aspirin; Carbonic Anhydrase Inhibitors; Coho

2008
Behavioral disorders in children with idiopathic intracranial hypertension.
    Journal of child neurology, 2008, Volume: 23, Issue:4

    Topics: Acetazolamide; Adolescent; Carbonic Anhydrase Inhibitors; Child; Child Behavior Disorders; Follow-Up

2008
Acetazolamide in control of acute mountain sickness.
    Lancet (London, England), 1981, Jan-24, Volume: 1, Issue:8213

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Carbon Dioxide; Clinical Trials as Topic; Do

1981
Benign cough headache is responsive to acetazolamide.
    Neurology, 2000, Jul-12, Volume: 55, Issue:1

    Topics: Acetazolamide; Aged; Cerebrospinal Fluid Pressure; Female; Headache; Humans; Male

2000
Effect of high elevation upon physical proficiency, cognitive functioning and subjective symptomatology.
    Perceptual and motor skills, 1968, Volume: 26, Issue:1

    Topics: Acetazolamide; Adult; Altitude; Back Pain; Cognition; Constipation; Depression; Headache; Humans; Hy

1968
Effect of acetazolamide on acute mountain sickness.
    The New England journal of medicine, 1968, Oct-17, Volume: 279, Issue:16

    Topics: Acetazolamide; Acute Disease; Adult; Alkalosis; Altitude; Bicarbonates; Blood; Blood Pressure; Carbo

1968
Carbon dioxide response curves at altitude.
    Aerospace medicine, 1971, Volume: 42, Issue:10

    Topics: Acetazolamide; Acid-Base Equilibrium; Adult; Alkalosis; Altitude; Carbon Dioxide; Headache; Humans;

1971

Other Studies

83 other studies available for acetazolamide and Bilateral Headache

ArticleYear
Neurosarcoidosis Presenting as Ophthalmoplegic Headache Managed With Acetazolamide.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2023, Dec-01, Volume: 43, Issue:4

    Topics: Acetazolamide; Central Nervous System Diseases; Headache; Humans; Ophthalmoplegia

2023
Dural Venous Sinus Stenting in Idiopathic Intracranial Hypertension: A National Database Study of 541 Patients.
    World neurosurgery, 2022, Volume: 167

    Topics: Acetazolamide; Cranial Sinuses; Dizziness; Female; Headache; Humans; Intracranial Hypertension; Male

2022
Pediatric myelin oligodendrocyte glycoprotein antibody associated disease-Asymmetric papilledema and elevated ICP are two of the chameleons: A case report.
    Medicine, 2023, Feb-22, Volume: 102, Issue:8

    Topics: Acetazolamide; Headache; Humans; Intracranial Hypertension; Male; Myelin-Oligodendrocyte Glycoprotei

2023
Treatment with GLP-1 receptor agonists is associated with significant weight loss and favorable headache outcomes in idiopathic intracranial hypertension.
    The journal of headache and pain, 2023, Jul-18, Volume: 24, Issue:1

    Topics: Acetazolamide; Adult; Female; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Headache; H

2023
Pediatric intracranial hypertension. Experience from 2 Tertiary Centers.
    Neurosciences (Riyadh, Saudi Arabia), 2019, Volume: 24, Issue:4

    Topics: Acetazolamide; Child; Child, Preschool; Diuretics; Female; Headache; Hospitals, Pediatric; Humans; I

2019
BARIATRIC SURGERY AS A TREATMENT FOR IDIOPATHIC INTRACRANIAL HYPERTENSION IN A MALE ADOLESCENT: CASE REPORT.
    Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2020, Volume: 38

    Topics: Acetazolamide; Adolescent; Aftercare; Bariatric Surgery; Diuretics; Fundus Oculi; Headache; Humans;

2020
Decadron, Diamox, and Zantac: A Novel Combination for Ventricular Shunt Failure in Pediatric Neurosurgical Patients.
    Pediatric emergency care, 2021, Dec-01, Volume: 37, Issue:12

    Topics: Acetazolamide; Child; Headache; Heart Failure; Humans; Hydrocephalus; Ranitidine; Reoperation; Retro

2021
The role of opening CSF pressure in response to treatment for idiopathic intracranial hypertension (IIH).
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 76

    Topics: Acetazolamide; Adult; Anticonvulsants; Cerebrospinal Fluid Pressure; Diuretics; Female; Headache; Hu

2020
Effect of Shunting on Visual Outcomes and Headache in Patients with Idiopathic Intracranial Hypertension.
    World neurosurgery, 2020, Volume: 142

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid Shunts; Cohort Studies; Dip

2020
Unusual presentation of idiopathic intracranial hypertension.
    BMJ case reports, 2020, May-31, Volume: 13, Issue:5

    Topics: Acetazolamide; Adult; Diagnosis, Differential; Diplopia; Headache; Humans; Intracranial Hypertension

2020
Antipsychotic pitfalls: idiopathic intracranial hypertension and antipsychotic-induced weight gain.
    BMJ case reports, 2020, Jun-30, Volume: 13, Issue:6

    Topics: Acetazolamide; Adult; Antipsychotic Agents; Depressive Disorder, Major; Drug Substitution; Female; H

2020
Around Manaslu Ultramarathon: Diarrhea Is Still the King.
    Wilderness & environmental medicine, 2017, Volume: 28, Issue:4

    Topics: Acetaminophen; Acetazolamide; Altitude; Altitude Sickness; Analgesics, Non-Narcotic; Anti-Bacterial

2017
Secondary Intracranial Hypertension in Pediatric Patients With Leukemia.
    Pediatric neurology, 2017, Volume: 77

    Topics: Acetazolamide; Adolescent; Anticonvulsants; Child; Child, Preschool; Cohort Studies; Female; Headach

2017
Pseudotumor cerebri in childhood and adolescence: data from a specialized service.
    Arquivos de neuro-psiquiatria, 2018, Volume: 76, Issue:11

    Topics: Acetazolamide; Adolescent; Child; Child, Preschool; Female; Headache; Humans; Male; Papilledema; Pse

2018
Intracranial hypertension in a patient with Class V lupus nephritis.
    Nephrology (Carlton, Vic.), 2019, Volume: 24, Issue:5

    Topics: Acetazolamide; Anticonvulsants; Brain; Diagnostic Techniques, Ophthalmological; Female; Glomerulonep

2019
Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report.
    Journal of medical case reports, 2019, Apr-19, Volume: 13, Issue:1

    Topics: Acetazolamide; Adult; Facial Paralysis; Female; Headache; Humans; Magnetic Resonance Imaging; Obesit

2019
[Idiopathic intracranial hypertension is a rare cause of headache in children].
    Ugeskrift for laeger, 2013, Mar-04, Volume: 175, Issue:10

    Topics: Acetazolamide; Child, Preschool; Diuretics; Headache; Humans; Male; Papilledema; Pseudotumor Cerebri

2013
Sudden bilateral vision loss and brain infarction following cosmetic hyaluronic acid injection.
    JAMA ophthalmology, 2013, Volume: 131, Issue:9

    Topics: Acetazolamide; Antihypertensive Agents; Aspirin; Blindness; Cerebral Infarction; Cosmetic Techniques

2013
[Benign intracranial hypertension secondary to hypoparathyroidism].
    Revista de neurologia, 2014, Jan-16, Volume: 58, Issue:2

    Topics: Acetazolamide; Adult; Calcitriol; Calcium Carbonate; Female; Headache; Humans; Hypocalcemia; Hypopar

2014
Unilateral headache and loss of vision. Acute primary angle closure glaucoma (APACG).
    BMJ (Clinical research ed.), 2014, Feb-04, Volume: 348

    Topics: Acetazolamide; Acute Disease; Anti-Inflammatory Agents; Diagnosis, Differential; Glaucoma, Angle-Clo

2014
Intracranial idiopathic hypertension: 1-year follow-up study.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35 Suppl 1

    Topics: Acetazolamide; Adult; Body Mass Index; Carbonic Anhydrase Inhibitors; Diagnostic Techniques, Ophthal

2014
[Bilateral carotid artery occlusion: prognosis and neurosonological features].
    Revista de neurologia, 2014, Jul-16, Volume: 59, Issue:2

    Topics: Acetazolamide; Aged; Aged, 80 and over; Angiography; Brain Ischemia; Carotid Stenosis; Collateral Ci

2014
Papilledema associated with puberty.
    Clinical pediatrics, 2015, Volume: 54, Issue:5

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Child; Diagnosis, Differential; Female; Headache; Huma

2015
[Pseudotumor cerebri in children with sickle cell disease].
    Journal francais d'ophtalmologie, 2015, Volume: 38, Issue:1

    Topics: Abducens Nerve Diseases; Acetazolamide; Adolescent; Anemia, Sickle Cell; Diplopia; Female; Headache;

2015
Cerebral proliferative angiopathy with papilledema.
    Clinical neurology and neurosurgery, 2015, Volume: 139

    Topics: Acetazolamide; Angiography, Digital Subtraction; Anterior Cerebral Artery; Cerebral Angiography; Diu

2015
Acetazolamide in vestibular migraine prophylaxis: a retrospective study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:10

    Topics: Acetazolamide; Adult; Aged; Analgesics; Female; Headache; Humans; Male; Middle Aged; Migraine Disord

2016
A case series of dural venous sinus stenting in idiopathic intracranial hypertension: association of outcomes with optical coherence tomography.
    The International journal of neuroscience, 2017, Volume: 127, Issue:2

    Topics: Acetazolamide; Adult; Anticonvulsants; Endovascular Procedures; Female; Follow-Up Studies; Headache;

2017
Presumed Pseudotumor Cerebri Syndrome After Withdrawal of Inhaled Glucocorticoids.
    Pediatrics, 2016, Volume: 137, Issue:6

    Topics: Acetazolamide; Administration, Inhalation; Asthma; Child; Diplopia; Female; Glucocorticoids; Growth;

2016
Probable pseudotumor cerebri complex in 25 children. Further support of a concept.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2017, Volume: 21, Issue:2

    Topics: Abducens Nerve Diseases; Acetazolamide; Adolescent; Cerebrospinal Fluid Pressure; Child; Child, Pres

2017
A Young Woman With Headaches and Blurry Vision.
    JAMA ophthalmology, 2017, 06-01, Volume: 135, Issue:6

    Topics: Acetazolamide; Angiogenesis Inhibitors; Bevacizumab; Carbonic Anhydrase Inhibitors; Choroidal Neovas

2017
Pseudotumor cerebri in pediatric age: role of obesity in the management of neurological impairments.
    Nutritional neuroscience, 2008, Volume: 11, Issue:1

    Topics: Acetazolamide; Adolescent; Cerebrospinal Fluid; Child; Child, Preschool; Cranial Nerve Diseases; Die

2008
Psychiatric symptoms in idiopathic intracranial hypertension.
    Psychiatry and clinical neurosciences, 2008, Volume: 62, Issue:3

    Topics: Acetazolamide; Adult; Borderline Personality Disorder; Depersonalization; Diagnosis, Differential; D

2008
[Idiopathic intracranial hypertension without headache detected during a routine health check].
    Rinsho shinkeigaku = Clinical neurology, 2008, Volume: 48, Issue:6

    Topics: Acetazolamide; Female; Fundus Oculi; Headache; Humans; Middle Aged; Papilledema; Physical Examinatio

2008
Low-dose acetylsalicylic Acid analog and acetazolamide for prevention of acute mountain sickness.
    High altitude medicine & biology, 2008,Winter, Volume: 9, Issue:4

    Topics: Acetazolamide; Acute Disease; Altitude Sickness; Aspirin; Dose-Response Relationship, Drug; Headache

2008
Acute comitant esotropia secondary to idiopathic intracranial hypertension in a child receiving recombinant human growth hormone.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2009, Volume: 44, Issue:1

    Topics: Acetazolamide; Acute Disease; Child; Dexamethasone; Diplopia; Drug Therapy, Combination; Esotropia;

2009
Choroidal infarction in fulminant idiopathic intracranial hypertension.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2010, Volume: 30, Issue:2

    Topics: Acetazolamide; Choroid; Choroid Diseases; Diuretics; Female; Headache; Humans; Infarction; Ophthalmi

2010
Acetazolamide therapy in meningeal involvement of nephrogenic systemic fibrosis.
    Internal medicine journal, 2010, Volume: 40, Issue:12

    Topics: Acetazolamide; Adult; Female; Headache; Humans; Meninges; Nephrogenic Fibrosing Dermopathy

2010
Pseudotumour cerebri in children: etiological, clinical features and treatment modalities.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2012, Volume: 16, Issue:4

    Topics: Acetazolamide; Adolescent; Anti-Inflammatory Agents; Anticonvulsants; Cerebrospinal Fluid Pressure;

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
Physiological risk factors for severe high-altitude illness: a prospective cohort study.
    American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Cohort Studies; Confidence Inte

2012
An 8-year-old girl with headache and syncope.
    Pediatric annals, 2011, Volume: 40, Issue:12

    Topics: Acetazolamide; Child; Diuretics; Female; Headache; Humans; Insulin Resistance; Obesity; Pseudotumor

2011
From menorrhagia to manometers.
    Archives of disease in childhood. Education and practice edition, 2012, Volume: 97, Issue:3

    Topics: Abducens Nerve Diseases; Acetazolamide; Adolescent; Anemia; Coombs Test; Diuretics; Fatigue; Female;

2012
Intracranial hypertension: was it really idiopathic?
    BMJ case reports, 2011, Apr-19, Volume: 2011

    Topics: Acetazolamide; Adult; Anticoagulants; Anticonvulsants; Diagnosis, Differential; Drug Therapy, Combin

2011
Conservative management in a rare case of spontaneous bilateral cerebellar haemorrhage.
    BMJ case reports, 2012, Jun-14, Volume: 2012

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetazolamide; Adult; Antiemetics; Cerebellum; Diuretics, O

2012
[Brain lesion].
    La Revue de medecine interne, 2012, Volume: 33, Issue:9

    Topics: Acetazolamide; Aged; Cerebrospinal Fluid Rhinorrhea; Confusion; Headache; Humans; Male; Pituitary Ne

2012
Paediatric idiopathic intracranial hypertension.
    BMJ case reports, 2013, Jan-24, Volume: 2013

    Topics: Acetazolamide; Child; Diuretics; Headache; Humans; Intracranial Hypertension; Male; Papilledema; Ven

2013
Idiopathic intracranial hypertension: is papilloedema inevitable?
    Archives of disease in childhood, 2002, Volume: 87, Issue:3

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Diagnosis, Differential; Fema

2002
Effect of acetazolamide on ocular hemodynamics in pseudotumor cerebri associated with inflammatory bowel disease.
    American journal of ophthalmology, 2002, Volume: 134, Issue:5

    Topics: Acetazolamide; Administration, Oral; Adult; Carbonic Anhydrase Inhibitors; Choroid; Crohn Disease; F

2002
Ophthalmologic involvement in the syndrome of headache, neurologic deficits, and cerebrospinal fluid lymphocytosis.
    Ophthalmology, 2003, Volume: 110, Issue:1

    Topics: Abducens Nerve Diseases; Acetazolamide; Adolescent; Carbonic Anhydrase Inhibitors; Female; Headache;

2003
Pseudotumor cerebri in a pre-pubescent child--case report.
    Optometry (St. Louis, Mo.), 2002, Volume: 73, Issue:11

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Child; Diplopia; Esotropia; Headache; Humans; Intracra

2002
Benign intracranial hypertension in association with acute lymphoblastic leukemia.
    Pediatric hematology and oncology, 2003, Volume: 20, Issue:2

    Topics: Acetazolamide; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chlorthalid

2003
A child with spinal cord AVM presenting with raised intracranial pressure.
    Neurology, 2003, May-27, Volume: 60, Issue:10

    Topics: Acetazolamide; Adolescent; Arteriovenous Malformations; Cervical Vertebrae; Diplopia; Dura Mater; Fe

2003
[Treatment of paramenstrual cephalea].
    Quaderni di clinica ostetrica e ginecologica, 1959, Volume: 14, Issue:2

    Topics: Acetazolamide; Female; Headache; Humans; Menstruation Disturbances; Prednisone

1959
Intracranial hypertension following epidural blood patch.
    Neurology, 2003, Nov-11, Volume: 61, Issue:9

    Topics: Acetazolamide; Adrenal Cortex Hormones; Adult; Blood Patch, Epidural; Headache; Humans; Injections,

2003
Steroid responsive late deterioration in Cryptococcus neoformans variety gattii meningitis.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Acetazolamide; Adult; Amphotericin B; Antifungal Agents; Arachnoiditis; Cerebral Infarction; Dexamet

2004
Transformed migraine is a cause of chronic daily headaches.
    Headache, 1999, Volume: 39, Issue:2

    Topics: Acetazolamide; Adult; Aged; Carbonic Anhydrase Inhibitors; Cerebellum; Female; Headache; Headache Di

1999
The physiologic basis of high-altitude diseases.
    Annals of internal medicine, 2005, Apr-05, Volume: 142, Issue:7

    Topics: Acetazolamide; Altitude Sickness; Drug Therapy, Combination; Ginkgo biloba; Headache; Humans; Phytot

2005
The physiologic basis of high-altitude diseases.
    Annals of internal medicine, 2005, Apr-05, Volume: 142, Issue:7

    Topics: Acetazolamide; Altitude Sickness; Drug Therapy, Combination; Ginkgo biloba; Headache; Humans; Phytot

2005
All-trans retinoic acid related headache in patients with acute promyelocytic leukemia: prophylaxis and treatment with acetazolamide.
    Leukemia research, 2005, Volume: 29, Issue:6

    Topics: Acetazolamide; Adult; Antineoplastic Agents; Headache; Humans; Leukemia, Promyelocytic, Acute; Male;

2005
An uncommon presentation of acute angle closure glaucoma.
    The Journal of emergency medicine, 2005, Volume: 29, Issue:1

    Topics: Acetazolamide; Acute Disease; Analgesics; Antihypertensive Agents; Diuretics; Drug Therapy, Combinat

2005
Idiopathic intracranial hypertension and sickle cell disease: two case reports.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2005, Volume: 40, Issue:6

    Topics: Acetazolamide; Adolescent; Adult; Anemia, Sickle Cell; Carbonic Anhydrase Inhibitors; Female; Headac

2005
[Benign intracranial hypertension and ulcerative colitis].
    Revista espanola de enfermedades digestivas, 2007, Volume: 99, Issue:2

    Topics: Acetazolamide; Adult; Anti-Inflammatory Agents, Non-Steroidal; Carbonic Anhydrase Inhibitors; Coliti

2007
Treatment of acute mountain sickness.
    JAMA, 1983, Sep-16, Volume: 250, Issue:11

    Topics: Acetazolamide; Acute Disease; Altitude Sickness; Headache; Humans; Hypoxia

1983
Pseudotumor cerebri responsive to acetazolamide.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:3

    Topics: Acetazolamide; Adolescent; Dexamethasone; Female; Headache; Humans; Pseudotumor Cerebri; Tetracyclin

1995
[Idiopathic intracranial hypertension and tetracycline].
    Harefuah, 1994, Volume: 127, Issue:1-2

    Topics: Acetazolamide; Adolescent; Adult; Female; Headache; Humans; Male; Papilledema; Pseudotumor Cerebri;

1994
Idiopathic intracranial hypertension and facial diplegia.
    Neurology, 1994, Volume: 44, Issue:2

    Topics: Acetazolamide; Adolescent; Diplopia; Facial Nerve; Facial Paralysis; Female; Headache; Humans; Pseud

1994
A young leukemic patient with headache.
    Journal of the Tennessee Medical Association, 1993, Volume: 86, Issue:11

    Topics: Acetazolamide; Adult; Female; Headache; Humans; Leukemia, Myeloid, Acute; Pseudotumor Cerebri

1993
Coexistence of migraine and idiopathic intracranial hypertension without papilledema.
    Neurology, 1996, Volume: 46, Issue:5

    Topics: Acetazolamide; Adolescent; Adult; Dihydroergotamine; Diuretics; Ergotamine; Female; Follow-Up Studie

1996
Chronic daily headache with migrainous features due to papilledema-negative idiopathic intracranial hypertension.
    Cephalalgia : an international journal of headache, 1996, Volume: 16, Issue:6

    Topics: Acetazolamide; Adult; Chronic Disease; Female; Headache; Humans; Intracranial Pressure; Middle Aged;

1996
Idiopathic intracranial hypertension in a young child without visual symptoms or signs.
    Headache, 1996, Volume: 36, Issue:9

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Child; Headache; Humans; Intracranial Pressure; Male;

1996
Pseudotumor cerebri sine papilledema with unilateral sixth nerve palsy.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 1998, Volume: 18, Issue:1

    Topics: Abducens Nerve; Acetazolamide; Adolescent; Cranial Nerve Diseases; Diplopia; Female; Headache; Human

1998
The blurred vision mystery. Idiopathic intracranial hypertension.
    Postgraduate medicine, 1998, Volume: 103, Issue:4

    Topics: Acetazolamide; Adult; Diuretics; Female; Headache; Humans; Intracranial Hypertension; Vision Disorde

1998
Pseudotumor cerebri as a presenting symptom of acute sinusitis in a child.
    Pediatric neurology, 1998, Volume: 19, Issue:2

    Topics: Acetazolamide; Acute Disease; Adolescent; Amoxicillin; Anti-Inflammatory Agents; Drug Therapy, Combi

1998
Communicating hydrocephalus secondary to diffuse meningeal spread of Wegener's granulomatosis: case report and literature review.
    Neurosurgery, 1998, Volume: 43, Issue:6

    Topics: Acetazolamide; Anti-Inflammatory Agents; Combined Modality Therapy; Cranial Nerve Diseases; Cyclopho

1998
[Benign intracranial hypertension following minocycline].
    Harefuah, 1998, May-15, Volume: 134, Issue:10

    Topics: Acetazolamide; Adolescent; Anti-Bacterial Agents; Diuretics; Female; Headache; Humans; Minocycline;

1998
Therapeutic effectiveness of acetazolamide in hindbrain hernia headache.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2000, Volume: 21, Issue:2

    Topics: Acetazolamide; Adult; Cerebellar Diseases; Decompression, Surgical; Encephalocele; Headache; Humans;

2000
Metabolic acidosis and hyperventilation induced by acetazolamide in patients with central nervous system pathology.
    Anesthesiology, 2000, Volume: 93, Issue:6

    Topics: Acetazolamide; Acidosis; Adult; Carbonic Anhydrase Inhibitors; Craniocerebral Trauma; Female; Headac

2000
Idiopathic "benign" intracranial hypertension: case series and review.
    Journal of child neurology, 2001, Volume: 16, Issue:7

    Topics: Acetazolamide; Adolescent; Adrenal Cortex Hormones; Child; Child, Preschool; Diagnosis, Differential

2001
Asymptomatic idiopathic intracranial hypertension in young children.
    Journal of child neurology, 2002, Volume: 17, Issue:3

    Topics: Acetazolamide; Brain; Carbonic Anhydrase Inhibitors; Child, Preschool; Headache; Humans; Male; Papil

2002
Timolol. Hypotensive effect, used alone and in combination for treatment of increased intraocular pressure.
    Acta ophthalmologica, 1978, Volume: 56, Issue:4

    Topics: Acetazolamide; Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Drug Tolerance;

1978
Use of acetazolamide-challenge xenon CT in the assessment of cerebral blood flow dynamics in patients with arteriovenous malformations.
    AJNR. American journal of neuroradiology, 1990, Volume: 11, Issue:3

    Topics: Acetazolamide; Adolescent; Adult; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Female; H

1990
[Acute altitude sickness].
    Ugeskrift for laeger, 1987, Oct-12, Volume: 149, Issue:42

    Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Brain Edema; Female; Headache; Humans; Hypox

1987
Spectrum of benign intracranial hypertension in children and adolescents.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1985, Volume: 1, Issue:2

    Topics: Acetazolamide; Adolescent; Anti-Bacterial Agents; Brain Concussion; Cerebrospinal Fluid Shunts; Chil

1985
Altitude headache.
    Headache, 1972, Volume: 12, Issue:3

    Topics: Acetazolamide; Altitude; Ammonium Chloride; Aspirin; Furosemide; Headache; Humans; Hypoxia; Potassiu

1972