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acetazolamide and Benign Neoplasms, Brain

acetazolamide has been researched along with Benign Neoplasms, Brain in 23 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"The natural product primary sulfonamide, psammaplin C (1), when used in combination with clinically used chemotherapeutic drugs, including temozolomide, reverses multidrug resistance and increases survival in glioblastoma, a highly aggressive primary brain tumor."7.91Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma. ( Bua, S; Kopecka, J; Mujumdar, P; Poulsen, SA; Riganti, C; Supuran, CT, 2019)
"The aim of this study was to investigate the effect of perfusion computed tomography (PCT) with acetazolamide (ACZ) challenge and compare it to 10% carbon dioxide (CO(2)) challenge in rat C6 glioma."7.78Comparison between acetazolamide challenge and 10% carbon dioxide challenge perfusion CT in rat C6 glioma. ( Di, Y; Feng, XY; Guo, QY; Lu, N; Qiang, JW; Wang, YG; Zhang, JW, 2012)
"Temozolomide (TMZ) is used for treating glioblastoma."5.35Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells. ( Banik, NL; Das, A; Ray, SK, 2008)
"The natural product primary sulfonamide, psammaplin C (1), when used in combination with clinically used chemotherapeutic drugs, including temozolomide, reverses multidrug resistance and increases survival in glioblastoma, a highly aggressive primary brain tumor."3.91Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma. ( Bua, S; Kopecka, J; Mujumdar, P; Poulsen, SA; Riganti, C; Supuran, CT, 2019)
"The aim of this study was to investigate the effect of perfusion computed tomography (PCT) with acetazolamide (ACZ) challenge and compare it to 10% carbon dioxide (CO(2)) challenge in rat C6 glioma."3.78Comparison between acetazolamide challenge and 10% carbon dioxide challenge perfusion CT in rat C6 glioma. ( Di, Y; Feng, XY; Guo, QY; Lu, N; Qiang, JW; Wang, YG; Zhang, JW, 2012)
" Furthermore, the non-cytolytic and non-cytotoxic metronomic dosage of hydroxyurea and temozolomide had increased the DBM therapy outcome by strengthening anti-tumor capability."1.62A retrospective observational study on cases of anaplastic brain tumors treated with the Di Bella Method: A rationale and effectiveness. ( Borghetto, V; Costanzo, E; Di Bella, G, 2021)
"Temozolomide (TMZ) is used for treating glioblastoma."1.35Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells. ( Banik, NL; Das, A; Ray, SK, 2008)
"Rats bearing 9L brain tumors in situ were imaged during inhalation of room air and after administration of 100% oxygen + acetazolamide (ACZ) injected 15 mg/kg intravenously."1.30Functional magnetic resonance (fMR) imaging of a rat brain tumor model: implications for evaluation of tumor microvasculature and therapeutic response. ( Chau, RI; Grossman, Z; Mazurchuk, R; Straubinger, RM; Zhou, R, 1999)
"Acetazolamide caused CBF to increase by 70."1.29Cerebral blood flow in normal brain tissue of patients with intracranial tumors. ( Kumate, S; Nakayama, Y; Tanaka, A; Yoshinaga, S, 1996)
" We deem the initial dosage of 16 mg Millicorten/day to be therapeutically effective and adequate."1.28[Pseudotumor cerebri in pregnancy]. ( Benz, J; Zeller, R, 1990)
"The xenon CT method is an asset in the diagnosis of cerebral diseases since it provides information on functional changes in addition to the morphological findings."1.28[Non-invasive measurement of cerebrovascular circulation using xenon(s) computerized tomography. A review]. ( Nabi Nemati, M, 1990)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19905 (21.74)18.7374
1990's10 (43.48)18.2507
2000's3 (13.04)29.6817
2010's4 (17.39)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Said, HM1
Hagemann, C1
Carta, F1
Katzer, A1
Polat, B1
Staab, A1
Scozzafava, A1
Anacker, J1
Vince, GH1
Flentje, M1
Supuran, CT2
Mujumdar, P1
Kopecka, J1
Bua, S1
Riganti, C1
Poulsen, SA1
Di Bella, G1
Borghetto, V1
Costanzo, E1
Amiri, A1
Le, PU1
Moquin, A1
Machkalyan, G1
Petrecca, K1
Gillard, JW1
Yoganathan, N1
Maysinger, D1
Lu, N1
Di, Y1
Feng, XY1
Qiang, JW1
Zhang, JW1
Wang, YG1
Guo, QY1
Watling, CJ1
Cairncross, JG1
PATEISKY, K1
PETSCHE, H1
MEYER, M1
STARR, HJ1
Das, A1
Banik, NL1
Ray, SK1
Okudaira, Y1
Arai, H1
Sato, K1
Nariai, T1
Nakayama, Y1
Tanaka, A1
Kumate, S1
Yoshinaga, S1
Inao, S2
Kuchiwaki, H2
Yoshida, J2
Furuse, M1
Ichimi, K1
Shibayama, M1
Itoh, K1
Katoh, T1
Nishino, M1
Narita, N1
Gambhir, S1
Mazurchuk, R1
Zhou, R1
Straubinger, RM1
Chau, RI1
Grossman, Z1
Chang, CC2
Kuwana, N2
Ito, S2
Ikegami, T2
Yamamoto, I1
Kempski, O1
Staub, F1
Jansen, M1
Baethmann, A1
Zeller, R1
Benz, J1
Nabi Nemati, M1
Paine, RS1
Rubin, RC1
Henderson, ES1
Ommaya, AK1
Walker, MD1
Rall, DP1

Reviews

1 review available for acetazolamide and Benign Neoplasms, Brain

ArticleYear
Hydrocephalus.
    Pediatric clinics of North America, 1967, Volume: 14, Issue:4

    Topics: Acetazolamide; Arnold-Chiari Malformation; Brain Neoplasms; Cerebral Ventricles; Choroid Plexus; Dia

1967

Other Studies

22 other studies available for acetazolamide and Benign Neoplasms, Brain

ArticleYear
Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.
    Bioorganic & medicinal chemistry, 2013, Jul-01, Volume: 21, Issue:13

    Topics: Acetazolamide; Antigens, Neoplasm; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydras

2013
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma.
    Journal of medicinal chemistry, 2019, 04-25, Volume: 62, Issue:8

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases;

2019
A retrospective observational study on cases of anaplastic brain tumors treated with the Di Bella Method: A rationale and effectiveness.
    Neuro endocrinology letters, 2021, Nov-30, Volume: 42, Issue:7

    Topics: Acetazolamide; Antioxidants; Brain Neoplasms; Ditiocarb; Glioblastoma; Humans; Hydroxyurea; Melatoni

2021
Inhibition of carbonic anhydrase IX in glioblastoma multiforme.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2016, Volume: 109

    Topics: Acetazolamide; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhyd

2016
Comparison between acetazolamide challenge and 10% carbon dioxide challenge perfusion CT in rat C6 glioma.
    Academic radiology, 2012, Volume: 19, Issue:2

    Topics: Acetazolamide; Animals; Blood Flow Velocity; Brain Neoplasms; Carbon Dioxide; Cell Line, Tumor; Cere

2012
Acetazolamide therapy for symptomatic plateau waves in patients with brain tumors. Report of three cases.
    Journal of neurosurgery, 2002, Volume: 97, Issue:1

    Topics: Acetazolamide; Adult; Brain Neoplasms; Diuretics; Female; Glioblastoma; Humans; Intracranial Hyperte

2002
[Electroencephalographic and clinical effects of acetazolamide (diamox) in processes causing a rise in cerebral pressure and in epilepsy].
    Wiener medizinische Wochenschrift (1946), 1957, Jul-06, Volume: 107, Issue:27

    Topics: Acetazolamide; Brain; Brain Neoplasms; Electroencephalography; Epilepsy

1957
[Treatment of increase of the cerebral volume with electrolyte substitution and inhibition of carbonic anhydrase. With a contribution to the genesis of cerebral edema].
    Praxis, 1959, Sep-24, Volume: 48

    Topics: Acetazolamide; Brain Edema; Brain Neoplasms; Carbonic Anhydrases; Edema; Electrolytes; Humans; Neuro

1959
PSEUDOTUMOR CEREBRI. REPORT OF SIX CASES COMPARED WITH ONE CASE OF PSEUDOPAPILLEDEMA.
    The Medical annals of the District of Columbia, 1964, Volume: 33

    Topics: Acetazolamide; Brain Diseases; Brain Neoplasms; Chlorothiazide; Diagnosis; Diet, Sodium-Restricted;

1964
Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells.
    Cancer investigation, 2008, Volume: 26, Issue:4

    Topics: Acetazolamide; Apoptosis; Aquaporin 1; Brain Edema; Brain Neoplasms; Calpain; Carbonic Anhydrases; C

2008
Cerebral blood flow alteration by acetazolamide during carotid balloon occlusion: parameters reflecting cerebral perfusion pressure in the acetazolamide test.
    Stroke, 1996, Volume: 27, Issue:4

    Topics: Acetazolamide; Blood Pressure; Blood Volume; Brain; Brain Neoplasms; Carotid Artery, Internal; Cathe

1996
Comparison of measurement between Xe/CT CBF and PET in cerebrovascular disease and brain tumor.
    Acta neurologica Scandinavica. Supplementum, 1996, Volume: 166

    Topics: Acetazolamide; Adult; Aged; Artifacts; Blood Flow Velocity; Brain; Brain Neoplasms; Cerebrovascular

1996
Cerebral blood flow in normal brain tissue of patients with intracranial tumors.
    Neurologia medico-chirurgica, 1996, Volume: 36, Issue:10

    Topics: Acetazolamide; Adolescent; Adult; Aged; Aged, 80 and over; Arachnoid Cysts; Astrocytoma; Brain Ische

1996
Magnetic resonance imaging quantitation of superior sagittal sinus flow: correlation to cerebral blood flow measured by xenon-enhanced computed tomography.
    Neurological research, 1997, Volume: 19, Issue:1

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Artifacts; Brain; Brain Neoplasms; Cerebral Hemorrhag

1997
Assessment of vasoreactivity in brain edema by acetazolamide activation SPECT and PET.
    Acta neurochirurgica. Supplement, 1997, Volume: 70

    Topics: Acetazolamide; Adult; Aged; Brain; Brain Edema; Brain Neoplasms; Evaluation Studies as Topic; Humans

1997
Functional magnetic resonance (fMR) imaging of a rat brain tumor model: implications for evaluation of tumor microvasculature and therapeutic response.
    Magnetic resonance imaging, 1999, Volume: 17, Issue:4

    Topics: Acetazolamide; Animals; Brain; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Gliosarcoma; Image Pr

1999
Effects of peritumoural oedema on cerebral blood flow and cerebrovascular reactivity in patients with alert consciousness.
    European journal of nuclear medicine, 1999, Volume: 26, Issue:11

    Topics: Acetazolamide; Brain; Brain Edema; Brain Neoplasms; Cerebrovascular Circulation; Consciousness; Diur

1999
Impairment of cerebrovascular reactivity to acetazolamide in patients with normal pressure hydrocephalus.
    Nuclear medicine communications, 2000, Volume: 21, Issue:2

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Brain Injuries; Brain Neoplasms; Cerebrovascular Circ

2000
Molecular mechanisms of glial cell swelling in acidosis.
    Advances in neurology, 1990, Volume: 52

    Topics: Acetazolamide; Acidosis; Amiloride; Animals; Bicarbonates; Brain Neoplasms; Carrier Proteins; Cell S

1990
[Pseudotumor cerebri in pregnancy].
    Gynakologische Rundschau, 1990, Volume: 30, Issue:3

    Topics: Acetazolamide; Adult; Brain Neoplasms; Diagnosis, Differential; Female; Fetal Death; Humans; Pregnan

1990
[Non-invasive measurement of cerebrovascular circulation using xenon(s) computerized tomography. A review].
    Neurochirurgia, 1990, Volume: 33, Issue:3

    Topics: Acetazolamide; Adult; Brain Ischemia; Brain Neoplasms; Carotid Artery Diseases; Carotid Artery, Inte

1990
The production of cerebrospinal fluid in man and its modification by acetazolamide.
    Journal of neurosurgery, 1966, Volume: 25, Issue:4

    Topics: Acetazolamide; Adolescent; Adult; Brain Neoplasms; Cerebrospinal Fluid; Child; Glioma; Humans; Injec

1966