acetazolamide has been researched along with Benign Neoplasms, Brain in 23 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Excerpt | Relevance | Reference |
---|---|---|
"The natural product primary sulfonamide, psammaplin C (1), when used in combination with clinically used chemotherapeutic drugs, including temozolomide, reverses multidrug resistance and increases survival in glioblastoma, a highly aggressive primary brain tumor." | 7.91 | Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma. ( Bua, S; Kopecka, J; Mujumdar, P; Poulsen, SA; Riganti, C; Supuran, CT, 2019) |
"The aim of this study was to investigate the effect of perfusion computed tomography (PCT) with acetazolamide (ACZ) challenge and compare it to 10% carbon dioxide (CO(2)) challenge in rat C6 glioma." | 7.78 | Comparison between acetazolamide challenge and 10% carbon dioxide challenge perfusion CT in rat C6 glioma. ( Di, Y; Feng, XY; Guo, QY; Lu, N; Qiang, JW; Wang, YG; Zhang, JW, 2012) |
"Temozolomide (TMZ) is used for treating glioblastoma." | 5.35 | Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells. ( Banik, NL; Das, A; Ray, SK, 2008) |
"The natural product primary sulfonamide, psammaplin C (1), when used in combination with clinically used chemotherapeutic drugs, including temozolomide, reverses multidrug resistance and increases survival in glioblastoma, a highly aggressive primary brain tumor." | 3.91 | Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma. ( Bua, S; Kopecka, J; Mujumdar, P; Poulsen, SA; Riganti, C; Supuran, CT, 2019) |
"The aim of this study was to investigate the effect of perfusion computed tomography (PCT) with acetazolamide (ACZ) challenge and compare it to 10% carbon dioxide (CO(2)) challenge in rat C6 glioma." | 3.78 | Comparison between acetazolamide challenge and 10% carbon dioxide challenge perfusion CT in rat C6 glioma. ( Di, Y; Feng, XY; Guo, QY; Lu, N; Qiang, JW; Wang, YG; Zhang, JW, 2012) |
" Furthermore, the non-cytolytic and non-cytotoxic metronomic dosage of hydroxyurea and temozolomide had increased the DBM therapy outcome by strengthening anti-tumor capability." | 1.62 | A retrospective observational study on cases of anaplastic brain tumors treated with the Di Bella Method: A rationale and effectiveness. ( Borghetto, V; Costanzo, E; Di Bella, G, 2021) |
"Temozolomide (TMZ) is used for treating glioblastoma." | 1.35 | Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells. ( Banik, NL; Das, A; Ray, SK, 2008) |
"Rats bearing 9L brain tumors in situ were imaged during inhalation of room air and after administration of 100% oxygen + acetazolamide (ACZ) injected 15 mg/kg intravenously." | 1.30 | Functional magnetic resonance (fMR) imaging of a rat brain tumor model: implications for evaluation of tumor microvasculature and therapeutic response. ( Chau, RI; Grossman, Z; Mazurchuk, R; Straubinger, RM; Zhou, R, 1999) |
"Acetazolamide caused CBF to increase by 70." | 1.29 | Cerebral blood flow in normal brain tissue of patients with intracranial tumors. ( Kumate, S; Nakayama, Y; Tanaka, A; Yoshinaga, S, 1996) |
" We deem the initial dosage of 16 mg Millicorten/day to be therapeutically effective and adequate." | 1.28 | [Pseudotumor cerebri in pregnancy]. ( Benz, J; Zeller, R, 1990) |
"The xenon CT method is an asset in the diagnosis of cerebral diseases since it provides information on functional changes in addition to the morphological findings." | 1.28 | [Non-invasive measurement of cerebrovascular circulation using xenon(s) computerized tomography. A review]. ( Nabi Nemati, M, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (21.74) | 18.7374 |
1990's | 10 (43.48) | 18.2507 |
2000's | 3 (13.04) | 29.6817 |
2010's | 4 (17.39) | 24.3611 |
2020's | 1 (4.35) | 2.80 |
Authors | Studies |
---|---|
Said, HM | 1 |
Hagemann, C | 1 |
Carta, F | 1 |
Katzer, A | 1 |
Polat, B | 1 |
Staab, A | 1 |
Scozzafava, A | 1 |
Anacker, J | 1 |
Vince, GH | 1 |
Flentje, M | 1 |
Supuran, CT | 2 |
Mujumdar, P | 1 |
Kopecka, J | 1 |
Bua, S | 1 |
Riganti, C | 1 |
Poulsen, SA | 1 |
Di Bella, G | 1 |
Borghetto, V | 1 |
Costanzo, E | 1 |
Amiri, A | 1 |
Le, PU | 1 |
Moquin, A | 1 |
Machkalyan, G | 1 |
Petrecca, K | 1 |
Gillard, JW | 1 |
Yoganathan, N | 1 |
Maysinger, D | 1 |
Lu, N | 1 |
Di, Y | 1 |
Feng, XY | 1 |
Qiang, JW | 1 |
Zhang, JW | 1 |
Wang, YG | 1 |
Guo, QY | 1 |
Watling, CJ | 1 |
Cairncross, JG | 1 |
PATEISKY, K | 1 |
PETSCHE, H | 1 |
MEYER, M | 1 |
STARR, HJ | 1 |
Das, A | 1 |
Banik, NL | 1 |
Ray, SK | 1 |
Okudaira, Y | 1 |
Arai, H | 1 |
Sato, K | 1 |
Nariai, T | 1 |
Nakayama, Y | 1 |
Tanaka, A | 1 |
Kumate, S | 1 |
Yoshinaga, S | 1 |
Inao, S | 2 |
Kuchiwaki, H | 2 |
Yoshida, J | 2 |
Furuse, M | 1 |
Ichimi, K | 1 |
Shibayama, M | 1 |
Itoh, K | 1 |
Katoh, T | 1 |
Nishino, M | 1 |
Narita, N | 1 |
Gambhir, S | 1 |
Mazurchuk, R | 1 |
Zhou, R | 1 |
Straubinger, RM | 1 |
Chau, RI | 1 |
Grossman, Z | 1 |
Chang, CC | 2 |
Kuwana, N | 2 |
Ito, S | 2 |
Ikegami, T | 2 |
Yamamoto, I | 1 |
Kempski, O | 1 |
Staub, F | 1 |
Jansen, M | 1 |
Baethmann, A | 1 |
Zeller, R | 1 |
Benz, J | 1 |
Nabi Nemati, M | 1 |
Paine, RS | 1 |
Rubin, RC | 1 |
Henderson, ES | 1 |
Ommaya, AK | 1 |
Walker, MD | 1 |
Rall, DP | 1 |
1 review available for acetazolamide and Benign Neoplasms, Brain
Article | Year |
---|---|
Hydrocephalus.
Topics: Acetazolamide; Arnold-Chiari Malformation; Brain Neoplasms; Cerebral Ventricles; Choroid Plexus; Dia | 1967 |
22 other studies available for acetazolamide and Benign Neoplasms, Brain
Article | Year |
---|---|
Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.
Topics: Acetazolamide; Antigens, Neoplasm; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydras | 2013 |
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; | 2019 |
A retrospective observational study on cases of anaplastic brain tumors treated with the Di Bella Method: A rationale and effectiveness.
Topics: Acetazolamide; Antioxidants; Brain Neoplasms; Ditiocarb; Glioblastoma; Humans; Hydroxyurea; Melatoni | 2021 |
Inhibition of carbonic anhydrase IX in glioblastoma multiforme.
Topics: Acetazolamide; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhyd | 2016 |
Comparison between acetazolamide challenge and 10% carbon dioxide challenge perfusion CT in rat C6 glioma.
Topics: Acetazolamide; Animals; Blood Flow Velocity; Brain Neoplasms; Carbon Dioxide; Cell Line, Tumor; Cere | 2012 |
Acetazolamide therapy for symptomatic plateau waves in patients with brain tumors. Report of three cases.
Topics: Acetazolamide; Adult; Brain Neoplasms; Diuretics; Female; Glioblastoma; Humans; Intracranial Hyperte | 2002 |
[Electroencephalographic and clinical effects of acetazolamide (diamox) in processes causing a rise in cerebral pressure and in epilepsy].
Topics: Acetazolamide; Brain; Brain Neoplasms; Electroencephalography; Epilepsy | 1957 |
[Treatment of increase of the cerebral volume with electrolyte substitution and inhibition of carbonic anhydrase. With a contribution to the genesis of cerebral edema].
Topics: Acetazolamide; Brain Edema; Brain Neoplasms; Carbonic Anhydrases; Edema; Electrolytes; Humans; Neuro | 1959 |
PSEUDOTUMOR CEREBRI. REPORT OF SIX CASES COMPARED WITH ONE CASE OF PSEUDOPAPILLEDEMA.
Topics: Acetazolamide; Brain Diseases; Brain Neoplasms; Chlorothiazide; Diagnosis; Diet, Sodium-Restricted; | 1964 |
Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells.
Topics: Acetazolamide; Apoptosis; Aquaporin 1; Brain Edema; Brain Neoplasms; Calpain; Carbonic Anhydrases; C | 2008 |
Cerebral blood flow alteration by acetazolamide during carotid balloon occlusion: parameters reflecting cerebral perfusion pressure in the acetazolamide test.
Topics: Acetazolamide; Blood Pressure; Blood Volume; Brain; Brain Neoplasms; Carotid Artery, Internal; Cathe | 1996 |
Comparison of measurement between Xe/CT CBF and PET in cerebrovascular disease and brain tumor.
Topics: Acetazolamide; Adult; Aged; Artifacts; Blood Flow Velocity; Brain; Brain Neoplasms; Cerebrovascular | 1996 |
Cerebral blood flow in normal brain tissue of patients with intracranial tumors.
Topics: Acetazolamide; Adolescent; Adult; Aged; Aged, 80 and over; Arachnoid Cysts; Astrocytoma; Brain Ische | 1996 |
Magnetic resonance imaging quantitation of superior sagittal sinus flow: correlation to cerebral blood flow measured by xenon-enhanced computed tomography.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Artifacts; Brain; Brain Neoplasms; Cerebral Hemorrhag | 1997 |
Assessment of vasoreactivity in brain edema by acetazolamide activation SPECT and PET.
Topics: Acetazolamide; Adult; Aged; Brain; Brain Edema; Brain Neoplasms; Evaluation Studies as Topic; Humans | 1997 |
Functional magnetic resonance (fMR) imaging of a rat brain tumor model: implications for evaluation of tumor microvasculature and therapeutic response.
Topics: Acetazolamide; Animals; Brain; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Gliosarcoma; Image Pr | 1999 |
Effects of peritumoural oedema on cerebral blood flow and cerebrovascular reactivity in patients with alert consciousness.
Topics: Acetazolamide; Brain; Brain Edema; Brain Neoplasms; Cerebrovascular Circulation; Consciousness; Diur | 1999 |
Impairment of cerebrovascular reactivity to acetazolamide in patients with normal pressure hydrocephalus.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Brain Injuries; Brain Neoplasms; Cerebrovascular Circ | 2000 |
Molecular mechanisms of glial cell swelling in acidosis.
Topics: Acetazolamide; Acidosis; Amiloride; Animals; Bicarbonates; Brain Neoplasms; Carrier Proteins; Cell S | 1990 |
[Pseudotumor cerebri in pregnancy].
Topics: Acetazolamide; Adult; Brain Neoplasms; Diagnosis, Differential; Female; Fetal Death; Humans; Pregnan | 1990 |
[Non-invasive measurement of cerebrovascular circulation using xenon(s) computerized tomography. A review].
Topics: Acetazolamide; Adult; Brain Ischemia; Brain Neoplasms; Carotid Artery Diseases; Carotid Artery, Inte | 1990 |
The production of cerebrospinal fluid in man and its modification by acetazolamide.
Topics: Acetazolamide; Adolescent; Adult; Brain Neoplasms; Cerebrospinal Fluid; Child; Glioma; Humans; Injec | 1966 |