acetazolamide has been researched along with Aura in 120 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of recurrent renal calculi containing calcium phosphate associated with long-term acetazolamide treatment for epilepsy." | 7.70 | Calcium phosphate stones during long-term acetazolamide treatment for epilepsy. ( Paisley, KE; Tomson, CR, 1999) |
| "Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)." | 7.65 | Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975) |
| "Severe osteomalacia was present in two epileptic patients who were under long-term treatment with congeners of phenytoin, phenobarbital, and acetazolamide." | 7.65 | Acetazolamide-accelerated anticonvulsant osteomalacia. ( Mallette, LE, 1977) |
| " For several years, she was treated for presumed focal seizures with preserved awareness and trialed on adequate dosing of several antiepileptic medications without improvement." | 5.91 | A De Novo HECW2 Variant in a Patient with Acetazolamide-Responsive Episodic Ataxia. ( Detyniecki, K; Margolesky, J; Schrauwen, I; Sharma, S; Tedesco Silva, LM, 2023) |
| " Responses to AZ were compared in women with different types of epilepsy and comparing continuous versus intermittent dosing using Fisher's exact tests." | 5.31 | Acetazolamide in women with catamenial epilepsy. ( Foldvary, N; Lee, J; Lim, LL; Mascha, E, 2001) |
| "Carbamazepine was given to 152 patients who were receiving multiple drug therapy for uncontrolled seizures." | 5.26 | Role of carbamazepine in reducing polypharmacy in epilepsy. ( Maheshwari, MC; Padmini, R, 1981) |
| "Phenytoin produced a lower serum level than the same dose of its sodium salt." | 5.25 | Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy. ( Gamstorp, I; Lilienberg, G; Norell, E, 1975) |
| "Acetazolamide is a beneficial adjunctive agent in the pharmacotherapy of epilepsy and should be considered in refractory epilepsy." | 4.79 | Acetazolamide in the treatment of seizures. ( Oles, KS; Reiss, WG, 1996) |
| " We identified a patient with a positive family history for episodic ataxia, who was originally diagnosed with epilepsy and treated with valproic acid." | 3.73 | CACNA1A mutation in a EA-2 patient responsive to acetazolamide and valproic acid. ( Bulman, DE; Friedman, JH; Scoggan, KA, 2006) |
| "Sulthiame is a carbonic anhydrase (CA) inhibitor with an anticonvulsant effect in the treatment of benign and symptomatic focal epilepsy in children." | 3.71 | Carbonic anhydrase inhibitor sulthiame reduces intracellular pH and epileptiform activity of hippocampal CA3 neurons. ( Bingmann, D; Bonnet, U; Hufnagel, A; Leniger, T; Widman, G; Wiemann, M, 2002) |
| "We report a case of recurrent renal calculi containing calcium phosphate associated with long-term acetazolamide treatment for epilepsy." | 3.70 | Calcium phosphate stones during long-term acetazolamide treatment for epilepsy. ( Paisley, KE; Tomson, CR, 1999) |
| "To clarify the effect of the clinical dosage of acetazolamide on growth in children with epilepsy or febrile convulsion, the standard scores of height and weight in 17 subjects receiving acetazolamide as an adjunct to unchanged monotherapy of antiepileptic drug were compared longitudinally through four phases: before antiepileptic drug administration, with monotherapy of antiepileptic drug, with acetazolamide in addition to monotherapy, and after acetazolamide discontinuation." | 3.69 | Growth suppression in children receiving acetazolamide with antiepileptic drugs. ( Abe, J; Futagi, Y; Otani, K, 1996) |
| " This is a syndrome of idiopathic generalized epilepsy that responds to treatment with valproic acid." | 3.68 | Eyelid twitching seizures and generalized tonic-clonic convulsions: a syndrome of idiopathic generalized epilepsy. ( Ferrendelli, JA; Miller, JW, 1990) |
| "Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)." | 3.65 | Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975) |
| " The levels of carbonic anhydrase B were determined in normal subjects, patients with hyperthyroidism, and patients with chronic obstructive lung disease and patients with epilepsy under treatment with acetazolamide, using the rapid assay method of single radial immunodiffusion." | 3.65 | Estimations of active and inactive carbonic anhydrase isozyme B in human red cells. ( Kondo, T; Murao, M; Takakuwa, E; Taniguchi, N, 1975) |
| "Severe osteomalacia was present in two epileptic patients who were under long-term treatment with congeners of phenytoin, phenobarbital, and acetazolamide." | 3.65 | Acetazolamide-accelerated anticonvulsant osteomalacia. ( Mallette, LE, 1977) |
| " Phenobarbital is usually given as well to prevent grand mal seizures." | 3.64 | Treatment of epilepsy. ( BAILEY, AA, 1963) |
| " A daily dose of 10mg/kg of AZA was first administered and then the dosage was increased up to 20mg/kg based on the clinical response and side effects." | 2.70 | Long-term effectiveness and side effects of acetazolamide as an adjunct to other anticonvulsants in the treatment of refractory epilepsies. ( Katayama, F; Miura, H; Takanashi, S, 2002) |
| "In women with epilepsy, seizures can be influenced by variations in sex hormone secretion during the menstrual cycle." | 2.42 | Catamenial epilepsy: pathophysiology, diagnosis, and management. ( Falcone, T; Foldvary-Schaefer, N, 2003) |
| " For several years, she was treated for presumed focal seizures with preserved awareness and trialed on adequate dosing of several antiepileptic medications without improvement." | 1.91 | A De Novo HECW2 Variant in a Patient with Acetazolamide-Responsive Episodic Ataxia. ( Detyniecki, K; Margolesky, J; Schrauwen, I; Sharma, S; Tedesco Silva, LM, 2023) |
| "Hyperammonemia was defined as a plasma ammonia level exceeding 100 μg/dl with reference to the standard range and previous reports." | 1.39 | Risk factors for hyperammonemia in pediatric patients with epilepsy. ( Imai, K; Inoue, K; Inoue, Y; Itoh, K; Kagawa, Y; Mishima, N; Takahashi, Y; Yamamoto, Y; Yazawa, R, 2013) |
| " Responses to AZ were compared in women with different types of epilepsy and comparing continuous versus intermittent dosing using Fisher's exact tests." | 1.31 | Acetazolamide in women with catamenial epilepsy. ( Foldvary, N; Lee, J; Lim, LL; Mascha, E, 2001) |
| "Carbamazepine was given to 152 patients who were receiving multiple drug therapy for uncontrolled seizures." | 1.26 | Role of carbamazepine in reducing polypharmacy in epilepsy. ( Maheshwari, MC; Padmini, R, 1981) |
| "Phenytoin produced a lower serum level than the same dose of its sodium salt." | 1.25 | Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy. ( Gamstorp, I; Lilienberg, G; Norell, E, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 87 (72.50) | 18.7374 |
| 1990's | 9 (7.50) | 18.2507 |
| 2000's | 14 (11.67) | 29.6817 |
| 2010's | 6 (5.00) | 24.3611 |
| 2020's | 4 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hen, N | 1 |
| Bialer, M | 1 |
| Yagen, B | 1 |
| Maresca, A | 1 |
| Aggarwal, M | 1 |
| Robbins, AH | 1 |
| McKenna, R | 1 |
| Scozzafava, A | 1 |
| Supuran, CT | 2 |
| McComsey, DF | 1 |
| Smith-Swintosky, VL | 1 |
| Parker, MH | 1 |
| Brenneman, DE | 1 |
| Malatynska, E | 1 |
| White, HS | 1 |
| Klein, BD | 1 |
| Wilcox, KS | 1 |
| Milewski, ME | 1 |
| Herb, M | 1 |
| Finley, MF | 1 |
| Liu, Y | 1 |
| Lubin, ML | 1 |
| Qin, N | 1 |
| Reitz, AB | 1 |
| Maryanoff, BE | 1 |
| Mishra, CB | 1 |
| Kumari, S | 1 |
| Angeli, A | 1 |
| Bua, S | 1 |
| Mongre, RK | 1 |
| Tiwari, M | 1 |
| Dinoi, G | 1 |
| Morin, M | 1 |
| Conte, E | 1 |
| Mor Shaked, H | 1 |
| Coppola, MA | 1 |
| D'Adamo, MC | 1 |
| Elpeleg, O | 1 |
| Liantonio, A | 1 |
| Hartmann, I | 1 |
| De Luca, A | 1 |
| Blunck, R | 1 |
| Russo, A | 1 |
| Imbrici, P | 1 |
| Tedesco Silva, LM | 1 |
| Sharma, S | 1 |
| Schrauwen, I | 1 |
| Margolesky, J | 1 |
| Detyniecki, K | 1 |
| Galán-Vidal, J | 1 |
| Socuéllamos, PG | 1 |
| Baena-Nuevo, M | 1 |
| Contreras, L | 1 |
| González, T | 1 |
| Pérez-Poyato, MS | 1 |
| Valenzuela, C | 1 |
| González-Lamuño, D | 1 |
| Gandarillas, A | 1 |
| Duan, L | 1 |
| Di, Q | 1 |
| Yamamoto, Y | 1 |
| Takahashi, Y | 1 |
| Imai, K | 1 |
| Mishima, N | 1 |
| Yazawa, R | 1 |
| Inoue, K | 1 |
| Itoh, K | 1 |
| Kagawa, Y | 1 |
| Inoue, Y | 1 |
| Hamidi, S | 1 |
| Avoli, M | 1 |
| Yu, H | 1 |
| Qi, GL | 1 |
| Wang, J | 1 |
| Chen, L | 1 |
| Deng, Z | 1 |
| Zhao, YS | 1 |
| Lei, SS | 1 |
| Zhu, XQ | 1 |
| Go, T | 1 |
| Nakagawara, J | 1 |
| Yee, AS | 1 |
| Longacher, JM | 1 |
| Staley, KJ | 1 |
| MERLIS, S | 1 |
| LOMBROSO, CT | 2 |
| DAVIDSON, DT | 1 |
| GROSSI-BIANCHI, ML | 1 |
| BORDELEAU, JM | 1 |
| LIVINGSTON, S | 2 |
| PETERSON, D | 1 |
| BOKS, L | 1 |
| GIROTTO, C | 2 |
| KAFER, JP | 2 |
| POCH, GF | 4 |
| WADA, T | 2 |
| SATO, T | 1 |
| MORITA, S | 1 |
| LUCY, J | 1 |
| SALDIAS, C | 1 |
| CABIESES, F | 1 |
| EIDELBERG, E | 1 |
| GOLLA, FL | 1 |
| HODGE, RS | 1 |
| AMENDOLA, E | 1 |
| RONCO, P | 1 |
| LENTI, C | 1 |
| MINDE, M | 1 |
| GARRETT, GM | 1 |
| TORRICO ROJAS, A | 1 |
| PATEISKY, K | 1 |
| PETSCHE, H | 1 |
| BONNET, H | 2 |
| HOLOWACH, J | 1 |
| THURSTON, DL | 1 |
| MANCEAUX, AG | 1 |
| SUTTER, JM | 1 |
| PELICIER, Y | 1 |
| PASCALIS, G | 1 |
| ROSS, IP | 1 |
| DUC, N | 1 |
| MINVIELLE, J | 1 |
| DANAN, M | 1 |
| WARD, AA | 1 |
| MORLOCK, NL | 1 |
| ROSENKRANZ, A | 1 |
| ROTH, G | 1 |
| CHAO, DH | 1 |
| PLUMB, RL | 1 |
| KATSNEL'SON, FIa | 1 |
| GORELIK, EI | 1 |
| BHASKARAN, D | 1 |
| SATYA NAND, D | 1 |
| BISWAS, SK | 1 |
| BAILEY, AA | 1 |
| TAKASE, M | 1 |
| FUKUSHIMA, Y | 1 |
| NISHIMURA, T | 1 |
| SCHOLL, ML | 1 |
| POIRE, R | 1 |
| ROYER, P | 1 |
| DEGRAEVE, M | 1 |
| RUSTIN, C | 1 |
| OLIVARES, L | 1 |
| JABBOUR, JT | 1 |
| SOREL, L | 1 |
| LEREBOULLET, J | 1 |
| GEORGIEV, VP | 1 |
| FURNADZHIEV, GP | 1 |
| HOLT, KS | 1 |
| MILLICHAP, JG | 6 |
| JONES, JD | 2 |
| RUDIS, BP | 1 |
| CHAO, D | 1 |
| DAVIS, SD | 1 |
| KIORBOE, E | 2 |
| SPINKS, A | 1 |
| WARING, WS | 1 |
| MIZUNO, T | 1 |
| MACGREGOR, M | 1 |
| JONGMANS, JW | 1 |
| DEJONG, RN | 1 |
| MAGEE, KR | 1 |
| CRAIG, WS | 1 |
| MACKINNON, JM | 1 |
| FORXYTHE, I | 1 |
| Foldvary-Schaefer, N | 1 |
| Falcone, T | 1 |
| Scoggan, KA | 1 |
| Friedman, JH | 1 |
| Bulman, DE | 1 |
| Iizuka, T | 1 |
| Sakai, F | 1 |
| Ide, T | 1 |
| Miyakawa, S | 1 |
| Sato, M | 1 |
| Yoshii, S | 1 |
| Lyall, DA | 1 |
| Olesen, OV | 1 |
| Mallow, DW | 1 |
| Herrick, MK | 1 |
| Gathman, G | 1 |
| Sato, J | 1 |
| Saito, A | 1 |
| Owada, E | 1 |
| Ito, K | 1 |
| Goto, T | 1 |
| Kawai, S | 1 |
| Kobayashi, Y | 1 |
| Maheshwari, MC | 1 |
| Padmini, R | 1 |
| Reiss, WG | 1 |
| Oles, KS | 1 |
| Futagi, Y | 1 |
| Otani, K | 1 |
| Abe, J | 1 |
| Heckmann, JG | 1 |
| Niedermeier, W | 1 |
| Neundörfer, B | 1 |
| Kubota, F | 1 |
| Kifune, A | 1 |
| Shibata, N | 1 |
| Akata, T | 1 |
| Takeuchi, K | 1 |
| Takahashi, S | 1 |
| Ohsawa, M | 1 |
| Takama, F | 1 |
| van Putten, MJ | 1 |
| Bosman-Vermeeren, JM | 1 |
| Brouwer, OF | 1 |
| Paisley, KE | 1 |
| Tomson, CR | 1 |
| Meierkord, H | 1 |
| Grünig, F | 1 |
| Gutschmidt, U | 1 |
| Gutierrez, R | 1 |
| Pfeiffer, M | 1 |
| Draguhn, A | 1 |
| Brückner, C | 1 |
| Heinemann, U | 1 |
| Hoddevik, GH | 1 |
| Lim, LL | 1 |
| Foldvary, N | 1 |
| Mascha, E | 1 |
| Lee, J | 1 |
| Sterzer, P | 1 |
| Meintzschel, F | 1 |
| Rösler, A | 1 |
| Lanfermann, H | 1 |
| Steinmetz, H | 1 |
| Sitzer, M | 1 |
| Vander Borght, T | 1 |
| Laloux, P | 1 |
| Maes, A | 1 |
| Salmon, E | 1 |
| Goethals, I | 1 |
| Goldman, S | 1 |
| Katayama, F | 1 |
| Miura, H | 1 |
| Takanashi, S | 1 |
| Leniger, T | 1 |
| Wiemann, M | 1 |
| Bingmann, D | 1 |
| Widman, G | 1 |
| Hufnagel, A | 1 |
| Bonnet, U | 1 |
| Jeavons, PM | 1 |
| Shaywitz, BA | 1 |
| Cohen, DJ | 1 |
| Bowers, MB | 1 |
| Kondo, T | 1 |
| Taniguchi, N | 1 |
| Murao, M | 1 |
| Takakuwa, E | 1 |
| Norell, E | 1 |
| Lilienberg, G | 1 |
| Gamstorp, I | 1 |
| Thomas, JA | 1 |
| Knotts, GR | 1 |
| Mallette, LE | 1 |
| Miller, JW | 1 |
| Ferrendelli, JA | 1 |
| Ryan, SW | 1 |
| Hartley, R | 1 |
| Forsythe, WI | 1 |
| Reynolds, EH | 2 |
| Chanarin, I | 2 |
| Matthews, DM | 1 |
| Di Cagno, L | 1 |
| Ravetto, A | 1 |
| Uchino, J | 1 |
| Esplin, DW | 1 |
| Zablocka, B | 1 |
| Jannasch, R | 1 |
| Wrighton, RJ | 1 |
| Johnson, AL | 1 |
| Preece, J | 1 |
| Gardner-Thorpe, C | 1 |
| Parsonage, MJ | 1 |
| Toothill, C | 1 |
| Leibovitz, U | 1 |
| Kutt, H | 1 |
| Louis, S | 1 |
| Halpern, LM | 2 |
| Julien, RM | 2 |
| Eeg-Olofsson, O | 1 |
| Gascon, GG | 1 |
| Brunia, CH | 1 |
| Buyze, G | 1 |
| DeVivo, DC | 2 |
| Pagliara, AS | 1 |
| Prensky, AL | 2 |
| Poser, CH | 1 |
| Tchicaloff, M | 1 |
| Lewis, JA | 1 |
| Scollo-Lavizzari, G | 1 |
| Palkes, H | 1 |
| Tanimukai, H | 1 |
| Inui, M | 1 |
| Hariguchi, S | 1 |
| Kaneko, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non-inferiority Prospective Randomized Trial of Acetazolamide Versus Diazepam in Patients With Continuous Spike and Wave in Sleep (CSWS)/Landau Kleffner Syndrome (LKS)[NCT02904265] | Phase 2/Phase 3 | 3 participants (Actual) | Interventional | 2016-09-30 | Terminated (stopped due to Lack of enrollment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Expect improved side effect profile of acetazolamide compared to diazepam at short-term follow up (NCT02904265)
Timeframe: 4-8 weeks of start of medications
| Intervention | Participants (Count of Participants) |
|---|---|
| Diazepam | 1 |
| Acetazolamide | 2 |
9 reviews available for acetazolamide and Aura
| Article | Year |
|---|---|
ANTICONVULSANT DRUGS.
Topics: Acetazolamide; Acetylcholine; Amides; Aminobutyrates; Anticonvulsants; Brain; Chemistry, Pharmaceuti | 1963 |
Catamenial epilepsy: pathophysiology, diagnosis, and management.
Topics: Acetazolamide; Adolescent; Adult; Animals; Anticonvulsants; Brain Edema; Bromides; Contraceptives, O | 2003 |
Acetazolamide in the treatment of seizures.
Topics: Acetazolamide; Adult; Anticonvulsants; Child; Drug Interactions; Epilepsy; Half-Life; Humans; Intest | 1996 |
[Central apnea in newborns].
Topics: Acetazolamide; Anticonvulsants; Apnea; Arnold-Chiari Malformation; Diagnosis, Differential; DiGeorge | 1999 |
[Acetazolamide--are there reasons for its revival in antiepileptic treatment?].
Topics: Acetazolamide; Adult; Anticonvulsants; Carbonic Anhydrase Inhibitors; Drug Tolerance; Epilepsy; Fema | 2000 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials | 1969 |
Effects of tetanization on transmitter dynamics.
Topics: Acetazolamide; Acetylcholine; Action Potentials; Animals; Biological Transport; Carbon Dioxide; Cell | 1969 |
[Antiepileptics. 39].
Topics: Acetazolamide; Adrenocorticotropic Hormone; Aminoglutethimide; Anticonvulsants; Barbiturates; Carbam | 1969 |
Epilepsy in the adolescent.
Topics: Acetazolamide; Adolescent; Age Factors; Alcoholic Intoxication; Amphetamine; Anticonvulsants; Attitu | 1974 |
5 trials available for acetazolamide and Aura
| Article | Year |
|---|---|
Effect of antiepileptic drug polytherapy on urinary pH in children and young adults.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Ther | 2009 |
Pravastatin improves cerebral vasomotor reactivity in patients with subcortical small-vessel disease.
Topics: Acetazolamide; Aged; Blood Flow Velocity; Cholesterol, LDL; Cognition Disorders; Dementia, Vascular; | 2001 |
Long-term effectiveness and side effects of acetazolamide as an adjunct to other anticonvulsants in the treatment of refractory epilepsies.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epil | 2002 |
Acetazolamide therapy.
Topics: Acetazolamide; Adult; Child; Double-Blind Method; Epilepsies, Myoclonic; Epilepsy; Humans | 1991 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials | 1969 |
107 other studies available for acetazolamide and Aura
| Article | Year |
|---|---|
Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV.
Topics: Anticonvulsants; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Crystallography, | 2011 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).
Topics: Absorption; Amides; Animals; Anticonvulsants; Dioxanes; Dogs; Drug Evaluation, Preclinical; Drug Res | 2013 |
Discovery of Potent Carbonic Anhydrase Inhibitors as Effective Anticonvulsant Agents: Drug Design, Synthesis, and In Vitro and In Vivo Investigations.
Topics: Animals; Anticonvulsants; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors | 2021 |
Clinical and Functional Study of a De Novo Variant in the PVP Motif of Kv1.1 Channel Associated with Epilepsy, Developmental Delay and Ataxia.
Topics: Acetazolamide; Ataxia; Epilepsy; HEK293 Cells; Humans; Kv1.1 Potassium Channel; Mutation; Potassium | 2022 |
A De Novo HECW2 Variant in a Patient with Acetazolamide-Responsive Episodic Ataxia.
Topics: Acetazolamide; Adult; Anticonvulsants; Ataxia; Epilepsy; Female; Humans; Infant, Newborn; Muscle Hyp | 2023 |
A novel loss-of-function mutation of the voltage-gated potassium channel Kv10.2 involved in epilepsy and autism.
Topics: Acetazolamide; Autistic Disorder; Epilepsy; Humans; Mutation; Potassium Channels; Potassium Channels | 2022 |
Acetazolamide Suppresses Multi-Drug Resistance-Related Protein 1 and P-Glycoprotein Expression by Inhibiting Aquaporins Expression in a Mesial Temporal Epilepsy Rat Model.
Topics: Acetazolamide; Animals; Aquaporin 4; Aquaporins; ATP Binding Cassette Transporter, Subfamily B; ATP | 2017 |
Risk factors for hyperammonemia in pediatric patients with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Dose-Response Rela | 2013 |
Carbonic anhydrase inhibition by acetazolamide reduces in vitro epileptiform synchronization.
Topics: 4-Aminopyridine; Acetazolamide; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Carbonic An | 2015 |
Aquaporin 4 inhibition decreased synthesis of cytokines by acetazolamide in the hippocampus of rats with pentrazol-induced chronic epilepsy.
Topics: Acetazolamide; Animals; Aquaporin 4; Chronic Disease; Cytokines; Epilepsy; Hippocampus; Kindling, Ne | 2016 |
[Newly developed techniques for brain function imaging using SPECT].
Topics: Acetazolamide; Aged; Brain; Cerebrovascular Circulation; Epilepsy; Humans; Male; Middle Aged; Tomogr | 2002 |
Convulsant and anticonvulsant effects on spontaneous CA3 population bursts.
Topics: Acetazolamide; Action Potentials; Animals; Anticonvulsants; Convulsants; Epilepsy; Hippocampus; Mode | 2003 |
Diamox; a carbonic anhydrase inhibitor; its use in epilepsy.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Diuretics; Epilepsy | 1954 |
Further evaluation of acetazolamide (diamox) in treatment of epilepsy.
Topics: Acetazolamide; Diuretics; Epilepsy; Hydro-Lyases | 1956 |
[Acetazoleamide (diamox) in the treatment of epilepsy; preliminary report].
Topics: Acetazolamide; Diuretics; Epilepsy | 1955 |
Ineffectiveness of diamox in the treatment of childhood epilepsy.
Topics: Acetazolamide; Child; Diuretics; Epilepsy; Humans; Hydro-Lyases; Infant | 1956 |
[Treatment of epilepsy with acetazolamide].
Topics: Acetazolamide; Epilepsy | 1956 |
[Treatment of epilepsy with acetazolamide].
Topics: Acetazolamide; Epilepsy | 1956 |
[Treatment of epilepsy with acetazolamide].
Topics: Acetazolamide; Epilepsy | 1956 |
[Treatment of epilepsy with acetazolamide].
Topics: Acetazolamide; Epilepsy | 1956 |
[Acetazolamide in control of epileptic seizures by the production of acidosis].
Topics: Acetazolamide; Acidosis; Epilepsy; Humans | 1956 |
[Acetazolamide in control of epileptic seizures by the production of acidosis].
Topics: Acetazolamide; Acidosis; Epilepsy; Humans | 1956 |
[Acetazolamide in control of epileptic seizures by the production of acidosis].
Topics: Acetazolamide; Acidosis; Epilepsy; Humans | 1956 |
[Acetazolamide in control of epileptic seizures by the production of acidosis].
Topics: Acetazolamide; Acidosis; Epilepsy; Humans | 1956 |
Diamox acetazolamide in treatment of epilepsy.
Topics: Acetazolamide; Epilepsy | 1957 |
Epilepsy: diamox and the metabolic approach.
Topics: Acetazolamide; Epilepsy | 1957 |
Electroencephalographic changes induced by the intravenous administration of acetazolamide (diamox) in epileptic patients.
Topics: Acetazolamide; Administration, Intravenous; Electroencephalography; Epilepsy; Pharmaceutical Prepara | 1957 |
Control of petit mal by acetazolamide.
Topics: Acetazolamide; Epilepsy; Epilepsy, Absence | 1957 |
[First reports on the use of diamox in epilepsy].
Topics: Acetazolamide; Epilepsy | 1956 |
[Effects of acetazolamide (Diamox) on the clinical manifestations & on the water-electrolyte balance (magnesium, potassium, calcium) in biopathic epileptics].
Topics: Acetazolamide; Calcium; Calcium, Dietary; Epilepsy; Humans; Magnesium; Potassium; Water-Electrolyte | 1956 |
Acetazolamide (diamox) in the treatment of epilepsy.
Topics: Acetazolamide; Epilepsy | 1957 |
[Diamox as an anticonvulsant in epilepsy].
Topics: Acetazolamide; Anticonvulsants; Epilepsy | 1957 |
[Electroencephalographic and clinical effects of acetazolamide (diamox) in processes causing a rise in cerebral pressure and in epilepsy].
Topics: Acetazolamide; Brain; Brain Neoplasms; Electroencephalography; Epilepsy | 1957 |
Acetazolamide in the treatment of epilepsy.
Topics: Acetazolamide; Epilepsy | 1957 |
[Critical study of the value of acetazolamide as an anticonvulsant].
Topics: Acetazolamide; Anticonvulsants; Epilepsy | 1957 |
A clinical evaluation of acetazolamide (diamox) in the treatment of epilepsy in children.
Topics: Acetazolamide; Child; Epilepsy; Humans; Infant | 1958 |
[Primidone & acetazolamide in the therapy of epilepsy].
Topics: Acetazolamide; Epilepsy; Humans; Primidone | 1958 |
[Acetazolamide in the treatment of epilepsy].
Topics: Acetazolamide; Epilepsy | 1958 |
Acetazolamide therapy in epilepsy.
Topics: Acetazolamide; Epilepsy | 1958 |
[Study on acetazolamide in the treatment of epilepsy].
Topics: Acetazolamide; Epilepsy | 1958 |
Effects of diamox on epileptic monkeys.
Topics: Acetazolamide; Animals; Epilepsy; Haplorhini; Humans | 1959 |
[Effect of carbonic anhydrase inhibitors on electroencephalograms in epilepsy in children].
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Child; Electroencephalography; Epilepsy; Humans; Infan | 1958 |
Diamox in epilepsy. A critical review of 178 case.
Topics: Acetazolamide; Child; Epilepsy; Humans; Infant | 1961 |
[Results of the use of diacarb in the treatment of various forms of epilepsy in childhood].
Topics: Acetazolamide; Epilepsy; Humans | 1961 |
Acetazolamide (diamox) in the treatment of epilepsy.
Topics: Acetazolamide; Epilepsy; Humans | 1959 |
Treatment of epilepsy.
Topics: Acetazolamide; Anticonvulsants; Automatism; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clon | 1963 |
Diamox acetazolamide in treatment of the epileptics with frequent seizures or status epilepticus.
Topics: Acetazolamide; Epilepsy; Seizures; Status Epilepticus | 1961 |
ANTIEPILEPTIC DRUGS.
Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Barbiturates; Bromides; Epilepsy; Ethosux | 1963 |
[CARBONIC ANHYDRASE INHIBITORS AS AN ANTIEPILEPTICS].
Topics: Acetazolamide; Anticonvulsants; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Enzyme Inhibitor | 1963 |
CURRENT CONCEPTS IN THERAPY: TREATMENT OF SEIZURE DISORDERS (EPILEPSY). (CONCLUDED FROM DECEMBER 12).
Topics: Acetazolamide; Anticonvulsants; Child; Chlordiazepoxide; Dextroamphetamine; Epilepsy; Epilepsy, Abse | 1963 |
[EXPERIMENTAL DETERMINATION OF ANTICONVULSANT PROPERTIES OF DICHLORPHENAMIDE BY ELECTROENCEPHALOGRAPHIC STUDY UNDER INTERMITTENT PHOTIC STIMULATION].
Topics: Acetazolamide; Adolescent; Alcoholism; Anticonvulsants; Anxiety; Bemegride; Dichlorphenamide; Electr | 1963 |
MORO REFLEX AND MYOCLONIC EPILEPSY. REPORT OF A CASE SEEMINGLY INDICATING A COMMON MECHANISM FOR BOTH.
Topics: Acetazolamide; Anticonvulsants; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Humans; Inf | 1963 |
THE INFANT WITH EPILEPSY.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Birth Injuries; Classific | 1963 |
[CLASSIFICATION OF EPILEPSY AND ITS TREATMENT].
Topics: Acetazolamide; Anticonvulsants; Barbiturates; Classification; Epilepsy; Humans; Hydantoins; Neurosur | 1963 |
[THE NEW ANTIEPILEPTIC AGENTS].
Topics: Acetazolamide; Adrenocorticotropic Hormone; Amitriptyline; Anticonvulsants; Chlordiazepoxide; Dichlo | 1963 |
[ON SOME ASPECTS OF EPILEPSY AND THE EFFECT OF ANTICONVULSANTS].
Topics: Acetazolamide; Anticonvulsants; Barbiturates; Bromides; Electroencephalography; Epilepsy; Humans; Hy | 1963 |
[ANTI-EPILEPSY DRUGS].
Topics: Acetazolamide; Aminobutyrates; Anticonvulsants; Barbiturates; Borates; Bromine; Chlorpromazine; Elec | 1963 |
EPILEPSY AND LUPUS ERYTHEMATOSUS.
Topics: Acetazolamide; Amphetamine; Anticonvulsants; Child; Dexamethasone; Diagnosis; Epilepsy; Lupus Erythe | 1964 |
MECHANISM OF ANTICONVULSANT ACTION OF KETOGENIC DIET. STUDIES IN ANIMALS WITH EXPERIMENTAL SEIZURES AND IN CHILDREN WITH PETIT MAL EPILEPSY.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Adolescent; Anticonvulsants; Barbiturates; Biomedica | 1964 |
CONVULSIVE EQUIVALENT SYNDROME OF CHILDHOOD.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Autonomic Nervous System Diseases; Child; Chlorpromazine | 1964 |
[TREATMENT OF EPILEPSY IN ADULTS. A BRIEF SURVEY OF THE CLINICAL PROBLEMS].
Topics: Acetazolamide; Anticonvulsants; Blood Chemical Analysis; Chloral Hydrate; Data Collection; Electroen | 1964 |
[DIAGNOSIS AND THERAPY OF CONVULSIVE DISEASES IN CHILDHOOD].
Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Amino Acids; Barbiturates; Brain Diseases; C | 1964 |
EPILEPSY IN CHILDHOOD: CLASSIFICATION AND TREATMENT.
Topics: Acetazolamide; Adrenal Cortex Hormones; Angiomatosis; Barbiturates; Child; Classification; Electroen | 1964 |
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepox | 1964 |
MEDICAL TREATMENT OF EPILEPSY IN THE ADULT.
Topics: Acetazolamide; Barbiturates; Bromides; Drug Therapy; Epilepsy; Hydantoins; Oxyphenbutazone | 1964 |
ACID-BASE, ELECTROLYTE, AND AMINO-ACID METABOLISM IN CHILDREN WITH PETIT MAL. ETIOLOGIC SIGNIFICANCE AND MODIFICATION BY ANTICONVULSANT DRUGS AND THE KETOGENIC DIET.
Topics: Acetazolamide; Acid-Base Equilibrium; Adrenocorticotropic Hormone; Amino Acids; Anticonvulsants; Bar | 1964 |
CHILD CARE IN GENERAL PRACTICE. CONVULSIONS IN INFANCY AND CHILDHOOD. II.
Topics: Acetazolamide; Anticonvulsants; Bromides; Child; Child Care; Chloral Hydrate; Diagnosis; Drug Therap | 1965 |
[DRUG THERAPY OF EPILEPSY. INTRODUCTION].
Topics: Acetazolamide; Barbiturates; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epi | 1965 |
A long-term follow-up of acetazolamide (diamox) in the treatment of epilepsy.
Topics: Acetazolamide; Epilepsy; Follow-Up Studies | 1960 |
CACNA1A mutation in a EA-2 patient responsive to acetazolamide and valproic acid.
Topics: Acetazolamide; Adult; Amino Acid Sequence; Animals; Anticonvulsants; Calcium Channels; Diagnosis, Di | 2006 |
Regional cerebral blood flow and cerebrovascular reactivity during chronic stage of stroke-like episodes in MELAS -- implication of neurovascular cellular mechanism.
Topics: Acetazolamide; Adult; Aged; Brain; Carbonic Anhydrases; Cerebral Arteries; Cerebrovascular Circulati | 2007 |
Unexpected control of a patient's refractory epilepsy when treating glaucoma with acetazolamide.
Topics: Acetazolamide; Adult; Anticonvulsants; Carbonic Anhydrase Inhibitors; Epilepsy; Female; Glaucoma; Hu | 2008 |
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatogra | 1967 |
Fetal exposure to anticonvulsant drugs. Detailed pathological study of a case.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Adult; Anticonvulsants; Brain; Cardiomegaly; Epilepsy; E | 1980 |
[Simultaneous determination of several antiepileptic drugs and its clinical application to some cases of multiple-drug administration].
Topics: Acetazolamide; Anticonvulsants; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Ther | 1982 |
Role of carbamazepine in reducing polypharmacy in epilepsy.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Ther | 1981 |
Growth suppression in children receiving acetazolamide with antiepileptic drugs.
Topics: Acetazolamide; Acidosis; Adolescent; Anticonvulsants; Body Height; Body Weight; Child; Child, Presch | 1996 |
[Indications for acetazolamide in neurology].
Topics: Acetazolamide; Brain; Epilepsy; Humans; Pseudotumor Cerebri; Vasodilation | 1998 |
Bone mineral density of epileptic patients on long-term antiepileptic drug therapy: a quantitative digital radiography study.
Topics: Absorptiometry, Photon; Acetazolamide; Adult; Anticonvulsants; Barbiturates; Bone Density; Epilepsy; | 1999 |
Calcium phosphate stones during long-term acetazolamide treatment for epilepsy.
Topics: Acetazolamide; Adult; Anticonvulsants; Calcium Phosphates; Epilepsy; Humans; Kidney Calculi; Male; R | 1999 |
Sodium bromide: effects on different patterns of epileptiform activity, extracellular pH changes and GABAergic inhibition.
Topics: Acetazolamide; Algorithms; Animals; Anticonvulsants; Bromides; Calcium; Carbonic Anhydrase Inhibitor | 2000 |
Acetazolamide in women with catamenial epilepsy.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Cohort Studies; Drug Therapy, Combination; Epilep | 2001 |
Guidelines for brain radionuclide imaging. Perfusion single photon computed tomography (SPECT) using Tc-99m radiopharmaceuticals and brain metabolism positron emission tomography (PET) using F-18 fluorodeoxyglucose. The Belgian Society for Nuclear Medicin
Topics: Acetazolamide; Adult; Brain; Brain Death; Cerebrovascular Disorders; Child; Craniocerebral Trauma; D | 2001 |
Carbonic anhydrase inhibitor sulthiame reduces intracellular pH and epileptiform activity of hippocampal CA3 neurons.
Topics: Acetazolamide; Animals; Anticonvulsants; Benzolamide; Carbonic Anhydrase Inhibitors; Epilepsy; Guine | 2002 |
Choice of drug therapy in epilepsy.
Topics: Acetazolamide; Anticonvulsants; Benzodiazepines; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; | 1977 |
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy | 1975 |
Estimations of active and inactive carbonic anhydrase isozyme B in human red cells.
Topics: Acetazolamide; Animals; Carbonic Anhydrases; Enzyme Activation; Epilepsy; Erythrocytes; Female; Hors | 1975 |
Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy.
Topics: Acetazolamide; Adolescent; Carbamazepine; Child; Child, Preschool; Contraceptives, Oral; Drug Intera | 1975 |
Epilepsy and other seizure disorders in children: drug management.
Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, T | 1976 |
Acetazolamide-accelerated anticonvulsant osteomalacia.
Topics: Acetazolamide; Adult; Anticonvulsants; Calcium; Epilepsy; Female; Humans; Mephobarbital; Osteomalaci | 1977 |
Eyelid twitching seizures and generalized tonic-clonic convulsions: a syndrome of idiopathic generalized epilepsy.
Topics: Acetazolamide; Adult; Epilepsy; Eyelid Diseases; Female; Humans; Phenytoin; Spasm; Valproic Acid | 1990 |
Chewable carbamazepine for children with epilepsy.
Topics: Acetazolamide; Adolescent; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilep | 1990 |
Acetazolamide in treatment of epilepsy.
Topics: Acetazolamide; Adult; Child; Epilepsy; Epilepsy, Absence; Humans | 1987 |
Neuropsychiatric aspects of anticonvulsant megaloblastic anaemia.
Topics: Acetazolamide; Adult; Anemia, Macrocytic; Epilepsy; Female; Folic Acid; Humans; Male; Middle Aged; P | 1968 |
[Remote sequels of hypsarhythmic encephalopathy].
Topics: Acetazolamide; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Barbiturates; Brain Diseases; C | 1966 |
[Electrolyte metabolism in diseases of the central nervous system in children. 2. Electrolyte metabolism in focal epilepsy].
Topics: Acetazolamide; Adrenocorticotropic Hormone; Child; Child, Preschool; Chlorine; Epilepsy; Humans; Inf | 1968 |
Drug treatment of convulsive disorders.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; E | 1972 |
Anticonvulsant drugs in idiopathic epilepsy.
Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mepho | 1970 |
Inter-relations of folic acid and vitamin B 12 in drug-treated epileptic patients.
Topics: Acetazolamide; Adolescent; Adult; Amphetamine; Anticonvulsants; Epilepsy; Epilepsy, Temporal Lobe; E | 1971 |
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography.
Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin | 1971 |
[Medical treatment of epilepsy].
Topics: Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; | 1971 |
Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.
Topics: Acetates; Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Dibenzazepines; Electroencephalog | 1972 |
Augmentation of cerebellar Purkinje cell discharge rate after diphenylhydantoin.
Topics: Acetazolamide; Action Potentials; Cerebellum; Electroencephalography; Epilepsy; Phenobarbital; Pheny | 1972 |
Effects of diphenylhydantoin and other antiepileptic drugs on epileptiform activity and Purkinje cell discharge rates.
Topics: Acetazolamide; Action Potentials; Animals; Anticonvulsants; Blood Pressure; Cats; Cerebellum; Electr | 1972 |
Experiences with Bivotril in treatment of epilepsy--particularly minor motor epilepsy--in mentally retarded children.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Child; Child, Preschool; Chlor | 1973 |
Serum copper levels and epilepsy.
Topics: Acetazolamide; Adolescent; Adult; Age Factors; Amphetamine; Anticonvulsants; Caffeine; Ceruloplasmin | 1972 |
Ketotic hypoglycemia and the ketogenic diet.
Topics: Acetazolamide; Acetone; Acidosis; Blood Glucose; Child, Preschool; Diet Therapy; Dietary Carbohydrat | 1973 |
Letter: Modification of therapy for exacerbation of seizures during menstruation.
Topics: Acetazolamide; Epilepsy; Female; Medroxyprogesterone; Menstruation Disturbances | 1974 |
[New methods of seizure treatment in epilepsy].
Topics: Acetazolamide; Anticonvulsants; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tempo | 1965 |
Treatment of convulsive disorders.
Topics: Acetazolamide; Epilepsy; Ethosuximide; Humans | 1972 |
[Biochemical aspects and general principles of anticonvulsive therapy].
Topics: Acetazolamide; Adolescent; Anticonvulsants; Barbiturates; Child, Preschool; Epilepsy; Humans; Hydant | 1972 |
Severe bradykinesia as a manifestation of toxicity to antiepileptic medications.
Topics: Acetazolamide; Anticonvulsants; Child; Epilepsy; Ethosuximide; Humans; Male; Mental Processes; Movem | 1971 |
Antiepileptic property of inhibitors of carbonic anhydrase.
Topics: Acetazolamide; Animals; Anticonvulsants; Brain; Carbonic Anhydrase Inhibitors; Electroconvulsive The | 1965 |