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acetazolamide and Astrocytoma

acetazolamide has been researched along with Astrocytoma in 1 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research Excerpts

ExcerptRelevanceReference
"Acetazolamide caused CBF to increase by 70."1.29Cerebral blood flow in normal brain tissue of patients with intracranial tumors. ( Kumate, S; Nakayama, Y; Tanaka, A; Yoshinaga, S, 1996)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakayama, Y1
Tanaka, A1
Kumate, S1
Yoshinaga, S1

Other Studies

1 other study available for acetazolamide and Astrocytoma

ArticleYear
Cerebral blood flow in normal brain tissue of patients with intracranial tumors.
    Neurologia medico-chirurgica, 1996, Volume: 36, Issue:10

    Topics: Acetazolamide; Adolescent; Adult; Aged; Aged, 80 and over; Arachnoid Cysts; Astrocytoma; Brain Ische

1996