Page last updated: 2024-10-22

acetazolamide and Arrhythmia

acetazolamide has been researched along with Arrhythmia in 12 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"Arrhythmias were rare and similar with all treatments."6.79Effect of oxygen and acetazolamide on nocturnal cardiac conduction, repolarization, and arrhythmias in precapillary pulmonary hypertension and sleep-disturbed breathing. ( Bloch, KE; Hasler, ED; Hildenbrand, FF; Keusch, S; Müller-Mottet, S; Schumacher, DS; Speich, R; Ulrich, S, 2014)
" We evaluated whether hypobaric hypoxia during altitude travel further impairs cardiac repolarization in patients with OSA, and whether this is prevented by acetazolamide, a drug known to improve oxygenation and central sleep apnea at altitude."5.22Patients with Obstructive Sleep Apnea Have Cardiac Repolarization Disturbances when Travelling to Altitude: Randomized, Placebo-Controlled Trial of Acetazolamide. ( Bloch, KE; Duru, F; Furian, M; Kaufmann, B; Kohler, M; Latshang, TD; Nussbaumer-Ochsner, Y; Saguner, AM; Thurnheer, R; Ulrich, S, 2016)
"Arrhythmias were rare and similar with all treatments."2.79Effect of oxygen and acetazolamide on nocturnal cardiac conduction, repolarization, and arrhythmias in precapillary pulmonary hypertension and sleep-disturbed breathing. ( Bloch, KE; Hasler, ED; Hildenbrand, FF; Keusch, S; Müller-Mottet, S; Schumacher, DS; Speich, R; Ulrich, S, 2014)
"Patients with obstructive sleep apnea at altitude."2.52Patients with Obstructive Sleep Apnea at Altitude. ( Bloch, KE; Latshang, TD; Ulrich, S, 2015)
"However, the incidence of cardiac dysrhythmia was increased after the use of acetazolamide."1.31[A case of potassium-sensitive periodic paralysis with cardiac dysrhythmia controlled with imipramine and acetazolamide]. ( Endo, T; Fujimori, J; Itoyama, Y; Onodera, H; Shiga, Y; Takahashi, T; Takeda, A; Tateyama, M; Yoshimoto, T, 2001)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19906 (50.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schumacher, DS1
Müller-Mottet, S1
Hasler, ED1
Hildenbrand, FF1
Keusch, S1
Speich, R1
Bloch, KE3
Ulrich, S3
Latshang, TD2
Kaufmann, B1
Nussbaumer-Ochsner, Y1
Furian, M1
Kohler, M1
Thurnheer, R1
Saguner, AM1
Duru, F1
PINES, I1
SALAZAR, E1
LOPEZ, T1
Guilleminault, C1
Silvestri, R1
Mondini, S1
Coburn, S1
Nakamagoe, K1
Fujita, T1
Ohkoshi, N1
Mizusawa, H1
Shoji, S1
Endo, T1
Takeda, A1
Shiga, Y1
Fujimori, J1
Takahashi, T1
Tateyama, M1
Onodera, H1
Itoyama, Y1
Yoshimoto, T1
Kishi, M1
Kurihara, T1
Lisak, RP1
Lebeau, J1
Tucker, SH1
Rowland, LP1
Gomensoro, JB1
Levitt, LP1
Rose, LI1
Dawson, DM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Sleep Related Breathing Disorders in Patients With Pulmonary Hypertension (CSRPH)[NCT01427192]Phase 223 participants (Actual)Interventional2010-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for acetazolamide and Arrhythmia

ArticleYear
Patients with Obstructive Sleep Apnea at Altitude.
    High altitude medicine & biology, 2015, Volume: 16, Issue:2

    Topics: Acetazolamide; Age Factors; Aged; Altitude; Altitude Sickness; Arrhythmias, Cardiac; Carbonic Anhydr

2015
[A case of potassium-sensitive periodic paralysis with cardiac dysrhythmia].
    Rinsho shinkeigaku = Clinical neurology, 1997, Volume: 37, Issue:3

    Topics: Abnormalities, Multiple; Acetazolamide; Adult; Arrhythmias, Cardiac; Carbonic Anhydrase Inhibitors;

1997
[Periodic paralysis with cardiac arrhythmia(Andersen's syndrome)].
    Ryoikibetsu shokogun shirizu, 2001, Issue:35

    Topics: Acetazolamide; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbonic Anhydrase Inhibitors; Diagno

2001

Trials

2 trials available for acetazolamide and Arrhythmia

ArticleYear
Effect of oxygen and acetazolamide on nocturnal cardiac conduction, repolarization, and arrhythmias in precapillary pulmonary hypertension and sleep-disturbed breathing.
    Chest, 2014, Volume: 146, Issue:5

    Topics: Acetazolamide; Administration, Oral; Aged; Arrhythmias, Cardiac; Carbonic Anhydrase Inhibitors; Cros

2014
Patients with Obstructive Sleep Apnea Have Cardiac Repolarization Disturbances when Travelling to Altitude: Randomized, Placebo-Controlled Trial of Acetazolamide.
    Sleep, 2016, Sep-01, Volume: 39, Issue:9

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Altitude; Arrhythmias, Cardiac; Carbonic Anhydrase In

2016

Other Studies

7 other studies available for acetazolamide and Arrhythmia

ArticleYear
Antiarrhythmic properties of chlorothiazide.
    Annals of the New York Academy of Sciences, 1958, Feb-03, Volume: 71, Issue:4

    Topics: Acetazolamide; Arrhythmias, Cardiac; Chlorothiazide

1958
Aging and sleep apnea: action of benzodiazepine, acetazolamide, alcohol, and sleep deprivation in a healthy elderly group.
    Journal of gerontology, 1984, Volume: 39, Issue:6

    Topics: Acetazolamide; Aged; Aging; Arrhythmias, Cardiac; Benzodiazepines; Drug Interactions; Electrocardiog

1984
New and old concepts in sarcoidosis.
    The Western journal of medicine, 1983, Volume: 138, Issue:4

    Topics: Acetazolamide; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Humans; Prednisone; Prop

1983
[A case of potassium-sensitive periodic paralysis with cardiac dysrhythmia controlled with imipramine and acetazolamide].
    No to shinkei = Brain and nerve, 2001, Volume: 53, Issue:4

    Topics: Acetazolamide; Adolescent; Adrenergic Uptake Inhibitors; Anticonvulsants; Arrhythmias, Cardiac; Drug

2001
Hyperkalemic periodic paralysis and cardiac arrhythmia.
    Neurology, 1972, Volume: 22, Issue:8

    Topics: Acetazolamide; Adolescent; Arrhythmias, Cardiac; Blood Glucose; Electrocardiography; Electromyograph

1972
[Use of hydergine in acute ischemic pathology of the brain].
    Acta neurologica latinoamericana, 1967, Volume: 13, Issue:1

    Topics: Acetazolamide; Adult; Aged; Aminophylline; Arrhythmias, Cardiac; Carbon Dioxide; Cerebrovascular Cir

1967
Hypokalemic periodic paralysis with arrhythmia.
    The New England journal of medicine, 1972, Feb-03, Volume: 286, Issue:5

    Topics: Acetazolamide; Arrhythmias, Cardiac; Child; Electrocardiography; Heart; Humans; Hyperkalemia; Male;

1972