acetazolamide has been researched along with Amyoplasia Congenita in 1 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Interestingly, her episodes of ataxia were abolished by the administration of acetazolamide, similar to the response observed in episodic ataxia associated with other ion channels." | 1.42 | A Gain-of-Function Mutation in NALCN in a Child with Intellectual Disability, Ataxia, and Arthrogryposis. ( Aoyagi, K; Hamdan, FF; Michaud, JL; Mulcahy, B; Nagamatsu, S; Rossignol, E; Rouleau, GA; Xie, L; Zhen, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aoyagi, K | 1 |
| Rossignol, E | 1 |
| Hamdan, FF | 1 |
| Mulcahy, B | 1 |
| Xie, L | 1 |
| Nagamatsu, S | 1 |
| Rouleau, GA | 1 |
| Zhen, M | 1 |
| Michaud, JL | 1 |
1 other study available for acetazolamide and Amyoplasia Congenita
| Article | Year |
|---|---|
A Gain-of-Function Mutation in NALCN in a Child with Intellectual Disability, Ataxia, and Arthrogryposis.
Topics: Acetazolamide; Animals; Arthrogryposis; Ataxia; Caenorhabditis elegans; Caenorhabditis elegans Prote | 2015 |