acetazolamide has been researched along with Adverse Drug Event in 12 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute heart failure is a leading cause of hospitalisations with an increasing economic and public health burden." | 7.30 | [Acetazolamide in acute heart failure]. ( Carballo, D; Carballo, S; Darbellay Farhoumand, P; Jolti, M, 2023) |
| "Acute heart failure is a leading cause of hospitalisations with an increasing economic and public health burden." | 3.30 | [Acetazolamide in acute heart failure]. ( Carballo, D; Carballo, S; Darbellay Farhoumand, P; Jolti, M, 2023) |
| "The multiple drug interactions in which CAIs are involved should be carefully considered when such drugs are used in combination with the drug classes mentioned above, as the risks of developing toxicity and serious side effects if the dosages are not adjusted are high." | 2.53 | Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. ( Supuran, CT, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Jolti, M | 1 |
| Darbellay Farhoumand, P | 1 |
| Carballo, D | 1 |
| Carballo, S | 1 |
| Alaei, M | 1 |
| Najmi, AK | 1 |
| Kausar, H | 1 |
| Akhtar, M | 1 |
| Supuran, CT | 1 |
| Clark, BG | 1 |
| Vestal, RE | 1 |
| Quigley, HA | 1 |
| Robertson, DM | 1 |
| Stankiewicz, A | 1 |
| Rintelen, F | 1 |
| Meyer, JP | 1 |
| Uvnäs, B | 1 |
| Westerholm, B | 1 |
| Schulte-Steinberg, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-label, Multi-center, Phase 1b Study to Investigate the Safety and Tolerability of SLC-0111 (WBI-5111) in Combination With Gemcitabine in Metastatic Pancreatic Ductal Adenocarcinoma Subjects Positive for Carbonic Anhydrase IX[NCT03450018] | Phase 1/Phase 2 | 30 participants (Anticipated) | Interventional | 2019-01-10 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for acetazolamide and Adverse Drug Event
| Article | Year |
|---|---|
Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors.
Topics: Acetazolamide; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Antibodies, Monoclonal; | 2016 |
The eye and adverse drug effects. Some selected considerations.
Topics: Acetazolamide; Amyl Nitrite; Anesthesia; Chloramphenicol; Chloroquine; Contraceptives, Oral; Dexamet | 1972 |
[Selected problems of pharmacology and toxicology of the eye].
Topics: Acetazolamide; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Drug-Related Side Effects an | 1970 |
1 trial available for acetazolamide and Adverse Drug Event
| Article | Year |
|---|---|
[Acetazolamide in acute heart failure].
Topics: Acetazolamide; Diuretics; Drug-Related Side Effects and Adverse Reactions; Heart Failure; Hospitaliz | 2023 |
8 other studies available for acetazolamide and Adverse Drug Event
| Article | Year |
|---|---|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
A prospective research study of anti-glaucoma drugs prescribing, utilization pattern and adverse drug reaction recording in a university hospital.
Topics: Acetazolamide; Adult; Adverse Drug Reaction Reporting Systems; Drug Prescriptions; Drug Therapy, Com | 2015 |
Adverse drug reactions in the elderly: case studies.
Topics: Acetazolamide; Aged; Anemia, Hemolytic; Bromocriptine; Captopril; Chlorpropamide; Cimetidine; Clonid | 1984 |
A reevaluation of glaucoma management.
Topics: Acetazolamide; Cataract; Costs and Cost Analysis; Drug-Related Side Effects and Adverse Reactions; E | 1984 |
[Realization of nonocular dangers resulting from general medical therapy in ocular affections].
Topics: Acetazolamide; Aged; Anticoagulants; Diuretics; Drug-Related Side Effects and Adverse Reactions; Ede | 1970 |
[Report on adverse effects of drugs (8)].
Topics: Acetazolamide; Antineoplastic Agents; Cyclofenil; Cyclohexanes; Drug and Narcotic Control; Drug-Rela | 1970 |
["Nil nocere" in drug pretreatment of surgical patients].
Topics: Acetazolamide; Adrenal Cortex Hormones; Anesthesia; Anti-Bacterial Agents; Anticoagulants; Antihyper | 1967 |