acetazolamide has been researched along with Acute Symptom Flare in 1 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Whether acetazolamide, a carbonic anhydrase inhibitor that reduces proximal tubular sodium reabsorption, can improve the efficiency of loop diuretics, potentially leading to more and faster decongestion in patients with acute decompensated heart failure with volume overload, is unclear." | 9.51 | Acetazolamide in Acute Decompensated Heart Failure with Volume Overload. ( Blouard, P; Bruckers, L; Chenot, F; Damman, K; Dauw, J; Derthoo, D; Dierckx, R; Droogne, W; Dupont, M; Filippatos, G; Lassus, J; Martens, P; Mebazaa, A; Meekers, E; Moubayed, S; Mullens, W; Nijst, P; Ruschitzka, F; Smolders, W; Tartaglia, K; Ter Maaten, JM; Troisfontaines, P; Verbrugge, FH, 2022) |
| "Whether acetazolamide, a carbonic anhydrase inhibitor that reduces proximal tubular sodium reabsorption, can improve the efficiency of loop diuretics, potentially leading to more and faster decongestion in patients with acute decompensated heart failure with volume overload, is unclear." | 5.51 | Acetazolamide in Acute Decompensated Heart Failure with Volume Overload. ( Blouard, P; Bruckers, L; Chenot, F; Damman, K; Dauw, J; Derthoo, D; Dierckx, R; Droogne, W; Dupont, M; Filippatos, G; Lassus, J; Martens, P; Mebazaa, A; Meekers, E; Moubayed, S; Mullens, W; Nijst, P; Ruschitzka, F; Smolders, W; Tartaglia, K; Ter Maaten, JM; Troisfontaines, P; Verbrugge, FH, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mullens, W | 1 |
| Dauw, J | 1 |
| Martens, P | 1 |
| Verbrugge, FH | 1 |
| Nijst, P | 1 |
| Meekers, E | 1 |
| Tartaglia, K | 1 |
| Chenot, F | 1 |
| Moubayed, S | 1 |
| Dierckx, R | 1 |
| Blouard, P | 1 |
| Troisfontaines, P | 1 |
| Derthoo, D | 1 |
| Smolders, W | 1 |
| Bruckers, L | 1 |
| Droogne, W | 1 |
| Ter Maaten, JM | 1 |
| Damman, K | 1 |
| Lassus, J | 1 |
| Mebazaa, A | 1 |
| Filippatos, G | 1 |
| Ruschitzka, F | 1 |
| Dupont, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-center, Randomized, Double-blind, Phase IV Clinical Trial on the Diuretic Effects of Acetazolamide in Patients With Decompensated Heart Failure and Volume OveRload[NCT03505788] | Phase 4 | 519 participants (Actual) | Interventional | 2018-11-11 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for acetazolamide and Acute Symptom Flare
| Article | Year |
|---|---|
Acetazolamide in Acute Decompensated Heart Failure with Volume Overload.
Topics: Acetazolamide; Acute Disease; Carbonic Anhydrase Inhibitors; Diuretics; Double-Blind Method; Heart F | 2022 |