Page last updated: 2024-10-22

acetazolamide and Acute Kidney Failure

acetazolamide has been researched along with Acute Kidney Failure in 27 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"BACKGROUND Acetazolamide (ACTZ) is commonly used in the prevention and treatment of various clinical conditions, and anuric acute kidney injury (AKI) is one of its known life-threatening complications."8.02Anuric Acute Kidney Injury Requiring Dialysis Following Acetazolamide Use for Cataract Surgery. ( Abou-Mrad, RM; Babu, RS; Ibrahim, M; Osman, N, 2021)
"Vancomycin associated acute kidney injury (vAKI) is a well known complication in pediatric patients."7.88Vancomycin associated acute kidney injury in pediatric patients. ( Akcan-Arikan, A; Dutta, A; Galati, M; Kam, C; Moffett, BS; Morris, J, 2018)
"Treatment with acetazolamide for pseudotumor cerebri (PTC) in a renal transplant patient led to an acute, but reversible deterioration in renal function."7.68Deteriorating renal function with acetazolamide in a renal transplant patient with pseudotumor cerebri. ( Chagnac, A; Floru, S; Gafter, U; Korzets, A; Zevin, D, 1993)
"Presented is a case of acute renal failure induced by acetazolamide therapy for glaucoma."7.65Renal failure associated with acetazolamide therapy for glaucoma. ( Howlett, SA, 1975)
"BACKGROUND Acetazolamide (ACTZ) is commonly used in the prevention and treatment of various clinical conditions, and anuric acute kidney injury (AKI) is one of its known life-threatening complications."4.02Anuric Acute Kidney Injury Requiring Dialysis Following Acetazolamide Use for Cataract Surgery. ( Abou-Mrad, RM; Babu, RS; Ibrahim, M; Osman, N, 2021)
"Lithium promotes the phosphorylation of glycogen synthase kinase-3β (GSK3β), and this reaction protects against acute kidney injury mediated by renal apoptosis."3.91Effect of acetazolamide on lithium reabsorption and lithium-induced GSK3β phosphorylation in rat kidney. ( Kawasaki, T; Nabekura, T; Tsuduki, M; Uwai, Y, 2019)
"Vancomycin associated acute kidney injury (vAKI) is a well known complication in pediatric patients."3.88Vancomycin associated acute kidney injury in pediatric patients. ( Akcan-Arikan, A; Dutta, A; Galati, M; Kam, C; Moffett, BS; Morris, J, 2018)
"Treatment with acetazolamide for pseudotumor cerebri (PTC) in a renal transplant patient led to an acute, but reversible deterioration in renal function."3.68Deteriorating renal function with acetazolamide in a renal transplant patient with pseudotumor cerebri. ( Chagnac, A; Floru, S; Gafter, U; Korzets, A; Zevin, D, 1993)
"A patient with ocular hypertension was treated with acetazolamide."3.67Tamm-Horsfall protein accumulation in glomeruli during acetazolamide-induced acute renal failure. ( Jondeau, G; Kanfer, A; Mougenot, B; Ronco, P; Rondeau, E; Rossert, J; Sraer, JD, 1989)
"The clinical histories of two patients are presented, who both developed haemorrhagic anuria after a short course of therapy with the carbonic anhydrase inhibitor, acetazolamide (Diamox)."3.66Acute renal failure from the use of acetazolamide (Diamox). ( Higenbottam, T; Ogg, CS; Saxton, HM, 1978)
"Presented is a case of acute renal failure induced by acetazolamide therapy for glaucoma."3.65Renal failure associated with acetazolamide therapy for glaucoma. ( Howlett, SA, 1975)
"Pretreatment with acetazolamide produced a similar alkaline urine as the bicarbonate loading (pH 8."1.27Effect of sodium bicarbonate preloading on ischemic renal failure. ( Atkins, JL, 1986)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199013 (48.15)18.7374
1990's2 (7.41)18.2507
2000's2 (7.41)29.6817
2010's6 (22.22)24.3611
2020's4 (14.81)2.80

Authors

AuthorsStudies
Matsuura, K1
Yoshida, T1
Uehara, T1
Yamada, S1
Yotsuida, H1
Hasegawa, M1
Katayose, S1
Yamada, K1
Yaginuma, Y1
Safaei-Asl, A1
Emami, S1
Baghersalimi, A1
Darbandi, B1
Rad, AH1
Badeli, H1
Uwai, Y1
Tsuduki, M1
Kawasaki, T1
Nabekura, T1
Habibzadeh, P1
Mofatteh, M1
Ghavami, S1
Roozbeh, J1
Abou-Mrad, RM1
Ibrahim, M1
Osman, N1
Babu, RS1
Liu, X1
Sii, F1
Horsburgh, J1
Shah, P1
El Hamamsy, M1
Kamal, N1
Bazan, NS1
El Haddad, M1
Moffett, BS1
Morris, J1
Kam, C1
Galati, M1
Dutta, A1
Akcan-Arikan, A1
Betten, DP1
Bridger, DJ1
Felton, BM1
Andringa, KK1
Agarwal, A1
Davidov, T1
Hong, JJ1
Malcynski, JT1
López-Menchero, R1
Albero, MD1
Barrachina, MD1
Alvarez, L1
Lankisch, PG1
Priebe, HJ1
Favre, L1
Vallotton, MB1
Reid, W1
Harrower, AD1
Korzets, A1
Gafter, U1
Floru, S1
Chagnac, A1
Zevin, D1
Epelde Gonzalo, F1
Llibre Bombardó, J1
Martínez Pérez, J1
Higenbottam, T1
Ogg, CS1
Saxton, HM1
Thiel, G1
Brunner, F1
Wunderlich, P1
Huguenin, M1
Bienko, B1
Torhorst, J1
Peters-Haefeli, L1
Kirchertz, EJ1
Peters, G1
Howlett, SA1
Rossert, J1
Rondeau, E1
Jondeau, G1
Ronco, P1
Mougenot, B1
Kanfer, A1
Sraer, JD1
Atkins, JL1
Rothe, KF1
Heisler, N1
Pochedly, C1
Maher, JF1
Rath, CE1
Schreiner, GE1
Passwell, J1
Boichis, H1
Cohen, BE1

Reviews

3 reviews available for acetazolamide and Acute Kidney Failure

ArticleYear
Role of hypoxia-inducible factors in acute kidney injury.
    Nephron. Clinical practice, 2014, Volume: 127, Issue:1-4

    Topics: Acetazolamide; Acute Kidney Injury; Adaptation, Physiological; Altitude; Animals; Barbiturates; Basi

2014
[Anuric acute renal failure due to acetazolamide].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2006, Volume: 26, Issue:6

    Topics: Acetazolamide; Acute Kidney Injury; Anuria; Back Pain; Diagnosis, Differential; Fluid Therapy; Furos

2006
Diuretics.
    International anesthesiology clinics, 1984,Spring, Volume: 22, Issue:1

    Topics: Acetazolamide; Acute Kidney Injury; Chlorothiazide; Diuretics; Diuretics, Osmotic; Ethacrynic Acid;

1984

Trials

2 trials available for acetazolamide and Acute Kidney Failure

ArticleYear
Normal saline, the known but least-examined fluid therapy method for preventing heme-induced nephropathy in children with glucose 6 phosphate dehydrogenase deficiency: a randomized controlled clinical trial.
    Pediatric nephrology (Berlin, Germany), 2023, Volume: 38, Issue:2

    Topics: Acetazolamide; Acute Kidney Injury; Child; Female; Fluid Therapy; Glucosephosphate Dehydrogenase Def

2023
Relationship of renal prostaglandins to three diuretics.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 14, Issue:3

    Topics: Acetazolamide; Acute Kidney Injury; Adult; Amiloride; Anti-Inflammatory Agents; Diuretics; Female; H

1984

Other Studies

22 other studies available for acetazolamide and Acute Kidney Failure

ArticleYear
Metabolic alkalosis following mitral valvuloplasty in a dog with preoperative acute kidney injury.
    Journal of the American Veterinary Medical Association, 2021, 11-01, Volume: 259, Issue:11

    Topics: Acetazolamide; Acute Kidney Injury; Alkalosis; Animals; Bicarbonates; Dog Diseases; Dogs; Hydrogen-I

2021
Effect of acetazolamide on lithium reabsorption and lithium-induced GSK3β phosphorylation in rat kidney.
    Die Pharmazie, 2019, 10-01, Volume: 74, Issue:10

    Topics: Acetazolamide; Acute Kidney Injury; Animals; Apoptosis; Glycogen Synthase Kinase 3 beta; Kidney; Lit

2019
The potential effectiveness of acetazolamide in the prevention of acute kidney injury in COVID-19: A hypothesis.
    European journal of pharmacology, 2020, Dec-05, Volume: 888

    Topics: Acetazolamide; Acute Kidney Injury; Angiotensin-Converting Enzyme 2; Carbonic Anhydrase Inhibitors;

2020
Anuric Acute Kidney Injury Requiring Dialysis Following Acetazolamide Use for Cataract Surgery.
    The American journal of case reports, 2021, Apr-23, Volume: 22

    Topics: Acetazolamide; Acute Kidney Injury; Anuria; Cataract; Humans; Male; Middle Aged; Renal Dialysis

2021
Anuric acute kidney injury due to low dose oral acetazolamide with hypercrystalluria.
    Clinical & experimental ophthalmology, 2017, Volume: 45, Issue:9

    Topics: Acetazolamide; Acute Kidney Injury; Administration, Oral; Anuria; Carbonic Anhydrase Inhibitors; Dia

2017
Evaluation of the effect of acetazolamide versus mannitol on cisplatin-induced nephrotoxicity, a pilot study.
    International journal of clinical pharmacy, 2018, Volume: 40, Issue:6

    Topics: Acetazolamide; Acute Kidney Injury; Adult; Aged; Antineoplastic Agents; Cisplatin; Diuretics; Female

2018
Vancomycin associated acute kidney injury in pediatric patients.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Acetazolamide; Acute Kidney Injury; Child; Child, Preschool; Clindamycin; Female; Hospital Mortality

2018
Profound alkalemia secondary to gastric outlet obstruction and acute renal insufficiency.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:2

    Topics: Acetazolamide; Acute Kidney Injury; Alkalosis; Carbonic Anhydrase Inhibitors; Combined Modality Ther

2013
Novel use of acetazolamide in the treatment of rhabdomyolysis-induced myoglobinuric renal failure.
    The Journal of trauma, 2006, Volume: 61, Issue:1

    Topics: Acetazolamide; Acute Kidney Injury; Adult; Carbonic Anhydrase Inhibitors; Humans; Male; Myoglobinuri

2006
[Conservative treatment of acute pancreatitis].
    Deutsche medizinische Wochenschrift (1946), 1982, Apr-23, Volume: 107, Issue:16

    Topics: Acetazolamide; Acute Disease; Acute Kidney Injury; Aftercare; Antacids; Aprotinin; Atropine; Bacteri

1982
Acetazolamide and symptomatic metabolic acidosis in mild renal failure.
    British medical journal (Clinical research ed.), 1982, Apr-10, Volume: 284, Issue:6322

    Topics: Acetazolamide; Acidosis; Acute Kidney Injury; Aged; Female; Humans

1982
Deteriorating renal function with acetazolamide in a renal transplant patient with pseudotumor cerebri.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1993, Volume: 21, Issue:3

    Topics: Acetazolamide; Acute Kidney Injury; Adult; Female; Humans; Kidney Transplantation; Pseudotumor Cereb

1993
[Acetazolamide induced acute renal failure without evidence of renal obstruction].
    Anales de medicina interna (Madrid, Spain : 1984), 1998, Volume: 15, Issue:8

    Topics: Acetazolamide; Acute Kidney Injury; Aged; Carbonic Anhydrase Inhibitors; Diuretics; Female; Humans

1998
Acute renal failure from the use of acetazolamide (Diamox).
    Postgraduate medical journal, 1978, Volume: 54, Issue:628

    Topics: Acetazolamide; Acute Kidney Injury; Anuria; Humans; Male; Middle Aged; Radiography; Ureter; Ureteral

1978
Protection of rat kidneys against HgCl2-induced acute renal failure by induction of high urine flow without renin suppression.
    Kidney international. Supplement, 1976, Volume: 6

    Topics: Acetazolamide; Acute Kidney Injury; Animals; Body Weight; Desoxycorticosterone; Diuresis; Furosemide

1976
Renal failure associated with acetazolamide therapy for glaucoma.
    Southern medical journal, 1975, Volume: 68, Issue:4

    Topics: Acetazolamide; Acute Kidney Injury; Aged; Bicarbonates; Blood Urea Nitrogen; Body Weight; Creatinine

1975
Tamm-Horsfall protein accumulation in glomeruli during acetazolamide-induced acute renal failure.
    American journal of nephrology, 1989, Volume: 9, Issue:1

    Topics: Acetazolamide; Acute Kidney Injury; Fluorescent Antibody Technique; Humans; Kidney Glomerulus; Male;

1989
Effect of sodium bicarbonate preloading on ischemic renal failure.
    Nephron, 1986, Volume: 44, Issue:1

    Topics: Acetazolamide; Acute Kidney Injury; Animals; Bicarbonates; Creatinine; Diuresis; Hydrogen-Ion Concen

1986
Correction of metabolic alkalosis by HCl and acetazolamide: effects on extracellular and intracellular acid-base status in rats in vivo.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:7

    Topics: Acetazolamide; Acid-Base Equilibrium; Acute Kidney Injury; Alkalosis; Animals; Extracellular Space;

1986
Hyperuricemia in leukemia and lymphoma.
    Postgraduate medicine, 1974, Volume: 55, Issue:6

    Topics: Acetazolamide; Acute Kidney Injury; Allopurinol; Antineoplastic Agents; Bicarbonates; Crystallizatio

1974
Hyperuricemia complicating leukemia: treatment with allopurinol and dialysis.
    Archives of internal medicine, 1969, Volume: 123, Issue:2

    Topics: Acetazolamide; Acute Kidney Injury; Adult; Allopurinol; Anuria; Bicarbonates; Blood Gas Analysis; Bl

1969
Hyperuricemic nephropathy. Report of a case of lymphoblastic lymphosarcoma.
    American journal of diseases of children (1960), 1970, Volume: 120, Issue:2

    Topics: Acetazolamide; Acute Kidney Injury; Allopurinol; Bicarbonates; Biopsy; Child; Humans; Leukemia, Lymp

1970