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acetazolamide and Acute Confusional Senile Dementia

acetazolamide has been researched along with Acute Confusional Senile Dementia in 8 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
" From a review of the literature, the optimal technique employs quantitative 15O-water PET imaging determinations of cerebral blood flow (CBF) and acetazolamide (ACZ) (1 g iv with measurements at 10- to 20-min post-administration) as the vasodilating agent."3.72Technical issues in the determination of cerebrovascular reserve in elderly subjects using 15O-water PET imaging. ( Boles Ponto, LL; Hichwa, RD; Leonard Watkins, G; Schultz, SK, 2004)
"The effects of cerebral amyloid angiopathy (CAA) on the function of cerebral blood vessels were analyzed applying cerebral blood volume (CBV)-based fMRI to transgenic arcA beta mice."1.36Vascular response to acetazolamide decreases as a function of age in the arcA beta mouse model of cerebral amyloidosis. ( Knobloch, M; Mueggler, T; Nitsch, RM; Princz-Kranz, FL; Rudin, M, 2010)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uekawa, K1
Hasegawa, Y1
Senju, S1
Nakagata, N1
Ma, M1
Nakagawa, T1
Koibuchi, N1
Kim-Mitsuyama, S1
Likitjaroen, Y1
Suwanwela, NC1
Phanthumchinda, K1
Princz-Kranz, FL1
Mueggler, T2
Knobloch, M1
Nitsch, RM1
Rudin, M2
Sturchler-Pierrat, C1
Baumann, D1
Rausch, M1
Staufenbiel, M1
Boles Ponto, LL1
Schultz, SK1
Leonard Watkins, G1
Hichwa, RD1
Knapp, WH1
Dannenberg, C1
Marschall, B1
Zedlick, D1
Löschmann, K1
Bettin, S1
Barthel, H1
Seese, A1
Pávics, L1
Grünwald, F1
Reichmann, K1
Horn, R1
Kitschenberg, A1
Hartmann, A1
Menzel, C1
Schomburg, AG1
Overbeck, B1
Csernay, L1
Biersack, HJ1
Bonte, FJ1
Devous, MD1
Reisch, JS1
Ajmani, AK1
Weiner, MF1
Hom, J1
Tintner, R1

Trials

1 trial available for acetazolamide and Acute Confusional Senile Dementia

ArticleYear
Changes in local cerebral blood flow by neuroactivation and vasoactivation in patients with impaired cognitive function.
    European journal of nuclear medicine, 1996, Volume: 23, Issue:8

    Topics: Acetazolamide; Aged; Alzheimer Disease; Brain; Cerebrovascular Circulation; Cognition Disorders; Fem

1996

Other Studies

7 other studies available for acetazolamide and Acute Confusional Senile Dementia

ArticleYear
Intracerebroventricular Infusion of Angiotensin-(1-7) Ameliorates Cognitive Impairment and Memory Dysfunction in a Mouse Model of Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2016, 04-23, Volume: 53, Issue:1

    Topics: Acetazolamide; Alzheimer Disease; Amyloid beta-Peptides; Angiotensin I; Animals; Avoidance Learning;

2016
Vasoreactivity induced by acetazolamide in patients with vascular dementia versus Alzheimer's disease.
    Journal of the neurological sciences, 2009, Aug-15, Volume: 283, Issue:1-2

    Topics: Acetazolamide; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cardiovascular Agents; Cerebrovasc

2009
Vascular response to acetazolamide decreases as a function of age in the arcA beta mouse model of cerebral amyloidosis.
    Neurobiology of disease, 2010, Volume: 40, Issue:1

    Topics: Acetazolamide; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cerebral Amyloid A

2010
Compromised hemodynamic response in amyloid precursor protein transgenic mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Aug-15, Volume: 22, Issue:16

    Topics: Acetazolamide; Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Bicuculline;

2002
Technical issues in the determination of cerebrovascular reserve in elderly subjects using 15O-water PET imaging.
    NeuroImage, 2004, Volume: 21, Issue:1

    Topics: Acetazolamide; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Attention; Blood Flow Velocity; Br

2004
Regional cerebral blood flow single-photon emission tomography with 99mTc-HMPAO and the acetazolamide test in the evaluation of vascular and Alzheimer's dementia.
    European journal of nuclear medicine, 1999, Volume: 26, Issue:3

    Topics: Acetazolamide; Aged; Alzheimer Disease; Brain; Cerebrovascular Circulation; Dementia, Vascular; Diag

1999
The effect of acetazolamide on regional cerebral blood flow in patients with Alzheimer's disease or stroke as measured by single-photon emission computed tomography.
    Investigative radiology, 1989, Volume: 24, Issue:2

    Topics: Acetazolamide; Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Circulation; Cerebrovascu

1989