acetazolamide has been researched along with Acquired Nephrogenic Diabetes Insipidus in 4 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To reduce lithium-induced nephrogenic diabetes insipidus (lithium-NDI), patients with bipolar disorder are treated with thiazide and amiloride, which are thought to induce antidiuresis by a compensatory increase in prourine uptake in proximal tubules." | 1.43 | Acetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus. ( Alsady, M; Baumgarten, R; de Groot, T; Deen, PM; Devuyst, O; Kortenoeven, ML; Loffing, J; Sinke, AP; Wetzels, JF, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Groot, T | 3 |
| Doornebal, J | 1 |
| Christensen, BM | 1 |
| Cockx, S | 1 |
| Sinke, AP | 2 |
| Baumgarten, R | 3 |
| Bedford, JJ | 1 |
| Walker, RJ | 1 |
| Wetzels, JFM | 1 |
| Deen, PMT | 2 |
| Alsady, M | 2 |
| Kortenoeven, MLA | 1 |
| Carmone, C | 1 |
| Neijman, K | 1 |
| Bekkenkamp-Grovenstein, M | 1 |
| Engelke, U | 1 |
| Wevers, R | 1 |
| Korstanje, R | 1 |
| Kortenoeven, ML | 1 |
| Devuyst, O | 1 |
| Loffing, J | 1 |
| Wetzels, JF | 1 |
| Deen, PM | 1 |
| Gordon, CE | 1 |
| Vantzelfde, S | 1 |
| Francis, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Correction of Hypernatremia by Intravenous Hypotonic Solution Compared to Enteral Water, Randomized Clinical Trial[NCT06061783] | 178 participants (Anticipated) | Interventional | 2023-11-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for acetazolamide and Acquired Nephrogenic Diabetes Insipidus
| Article | Year |
|---|---|
Lithium-induced NDI: acetazolamide reduces polyuria but does not improve urine concentrating ability.
Topics: Acetazolamide; Aged; Animals; Aquaporin 2; Blood Pressure; Diabetes Insipidus, Nephrogenic; Disease | 2017 |
Lithium induces aerobic glycolysis and glutaminolysis in collecting duct principal cells.
Topics: Acetazolamide; Animals; Antimanic Agents; Aquaporin 2; Carbonic Anhydrase Inhibitors; Carbonic Anhyd | 2018 |
Acetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus.
Topics: Acetazolamide; Amiloride; Animals; Aquaporin 2; Diabetes Insipidus, Nephrogenic; Diuretics; Female; | 2016 |
Acetazolamide in Lithium-Induced Nephrogenic Diabetes Insipidus.
Topics: Acetazolamide; Animals; Diabetes Insipidus, Nephrogenic; Disease Models, Animal; Humans; Lithium Com | 2016 |