acetazolamide has been researched along with Acquired Aphasia with Convulsive Disorder in 2 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fine, AL | 1 |
| Wirrell, EC | 1 |
| Wong-Kisiel, LC | 1 |
| Nickels, KC | 1 |
| Pisani, F | 1 |
| Seri, S | 1 |
| Pelliccia, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non-inferiority Prospective Randomized Trial of Acetazolamide Versus Diazepam in Patients With Continuous Spike and Wave in Sleep (CSWS)/Landau Kleffner Syndrome (LKS)[NCT02904265] | Phase 2/Phase 3 | 3 participants (Actual) | Interventional | 2016-09-30 | Terminated (stopped due to Lack of enrollment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Expect improved side effect profile of acetazolamide compared to diazepam at short-term follow up (NCT02904265)
Timeframe: 4-8 weeks of start of medications
| Intervention | Participants (Count of Participants) |
|---|---|
| Diazepam | 1 |
| Acetazolamide | 2 |
2 other studies available for acetazolamide and Acquired Aphasia with Convulsive Disorder
| Article | Year |
|---|---|
Acetazolamide for electrical status epilepticus in slow-wave sleep.
Topics: Acetazolamide; Anticonvulsants; Child; Electroencephalography; Female; Humans; Landau-Kleffner Syndr | 2015 |
Landau-Kleffner syndrome and atypical benign partial epilepsy of childhood: the effectiveness of acetazolamide.
Topics: Acetazolamide; Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Epilepsies | 1999 |