acetazolamide has been researched along with Acidosis, Respiratory in 47 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Acidosis, Respiratory: Respiratory retention of carbon dioxide. It may be chronic or acute.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetazolamide is an efficient alternative for treatment of patients with respiratory acidosis and metabolic alkalosis, particularly when other more common measures in this condition (discontinuation of diuretics and/or volemic replacement) have failed or are contraindicated." | 7.69 | [Efficacy of acetazolamide treatment of patients with hypercapnia and superimposed metabolic alkalosis]. ( Cancelo Suárez, P; del Portillo Rubí, A; Guillem Ares, E; Prada Mínguez, A; Prieto de Paula, JM; Sanz de la Fuente, H; Villamandos Nicás, V, 1997) |
| "Acetazolamide is an efficient alternative for treatment of patients with respiratory acidosis and metabolic alkalosis, particularly when other more common measures in this condition (discontinuation of diuretics and/or volemic replacement) have failed or are contraindicated." | 3.69 | [Efficacy of acetazolamide treatment of patients with hypercapnia and superimposed metabolic alkalosis]. ( Cancelo Suárez, P; del Portillo Rubí, A; Guillem Ares, E; Prada Mínguez, A; Prieto de Paula, JM; Sanz de la Fuente, H; Villamandos Nicás, V, 1997) |
| "Acetazolamide has been recognized as an effective treatment for acute mountain sickness." | 1.35 | Normoxic induction of cerebral HIF-1alpha by acetazolamide in rats: role of acidosis. ( Dou, T; Gu, G; Kang, Z; Li, R; Liu, Y; Lu, J; Ostrowski, RP; Peng, Z; Sun, X; Tao, H; Xu, J; Xu, W; Zhang, JH, 2009) |
| "During respiratory acidosis (pHo approximately 6." | 1.29 | Intracellular pH recovery during respiratory acidosis in perfused hearts. ( Grace, AA; Metcalfe, JC; Vandenberg, JI, 1994) |
| "During acute respiratory acidosis CSF [HCO3-] rose progressively with time in group I, and the mean values were 28." | 1.27 | Effects of acetazolamide on ionic composition of cisternal fluid during acute respiratory acidosis. ( Demeester, G; Javaheri, S; Leusen, I; Weyne, J, 1984) |
| "Consecutive states of acute respiratory alkalosis and acidosis were created by changing the inspired CO2 from 0% (room air) to 8% CO2." | 1.27 | Functional role of carbonic anhydrase in intestinal electrolyte transport. ( Birnbaum, GJ; Charney, AN; Johnstone, JN; Wagner, JD, 1986) |
| "The observation that some patients with mixed sleep apnea appear to have central apnea while relatively alkalotic and obstructive apnea while acidotic emphasizes the need for more careful and detailed characterization of apneic disorders with respect to their responses to body states and therapeutic agents." | 1.27 | Effect of metabolic acidosis upon sleep apnea. ( D'Souza, V; Diamond, E; Druz, WS; Sharp, JT, 1985) |
| "Patients with mixed chronic respiratory acidosis and metabolic alkalosis constitute a common subgroup of patients with chronic obstructive lung disease and carbon dioxide retention; these patients benefit from correction of the metabolic alkalosis." | 1.26 | Effect of metabolic alkalosis on respiratory function in patients with chronic obstructive lung disease. ( Bear, R; Feldman, R; Goldstein, M; Halperin, M; Hammeke, M; Handelsman, S; Ho, M; Phillipson, E, 1977) |
| "It appears that the respiratory acidosis secondary to the inhibition of red cell carbonic anhydrase is responsible for the increased toxicity; earlier work by others shows that acidosis increases the concentration of salicylate in the brain." | 1.25 | CO2 retention as a basis for increased toxicity of salicylate with acetazolamide: avoidance of increased toxicity with benzolamide. ( Liddell, NE; Maren, TH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (80.85) | 18.7374 |
| 1990's | 6 (12.77) | 18.2507 |
| 2000's | 1 (2.13) | 29.6817 |
| 2010's | 2 (4.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, J | 1 |
| Peng, Z | 1 |
| Li, R | 1 |
| Dou, T | 1 |
| Xu, W | 1 |
| Gu, G | 1 |
| Liu, Y | 1 |
| Kang, Z | 1 |
| Tao, H | 1 |
| Zhang, JH | 1 |
| Ostrowski, RP | 1 |
| Lu, J | 1 |
| Sun, X | 1 |
| Teppema, LJ | 1 |
| van Dorp, EL | 1 |
| Dahan, A | 1 |
| Prieto de Paula, JM | 2 |
| Franco Hidalgo, S | 1 |
| Borge Gallardo, L | 1 |
| Mayor Toranzo, E | 1 |
| GALDSTON, M | 1 |
| STORSTEIN, O | 1 |
| SEBELIEN, J | 1 |
| SCHWAB, M | 1 |
| ZUNIGA-CARO, A | 1 |
| ORREGO-PUELMA, H | 1 |
| THOMPSON, WT | 1 |
| RICHARDSON, W | 1 |
| WINGO, CF | 1 |
| CARTER, NW | 1 |
| SELDIN, DW | 1 |
| TENG, HC | 1 |
| BICK, HD | 1 |
| MEIER-SYDOW, J | 1 |
| HAUCH, HJ | 1 |
| MUETZ, R | 1 |
| BELL, AL | 1 |
| SMITH, CN | 1 |
| ANDREAE, E | 1 |
| Weaver, TE | 2 |
| Scott, WJ | 2 |
| Javaheri, S | 1 |
| Weyne, J | 1 |
| Demeester, G | 1 |
| Leusen, I | 1 |
| Henry, RP | 1 |
| Boutilier, RG | 1 |
| Tufts, BL | 1 |
| Vandenberg, JI | 1 |
| Metcalfe, JC | 1 |
| Grace, AA | 1 |
| Swenson, ER | 2 |
| Robertson, HT | 1 |
| Hlastala, MP | 1 |
| Hughes, JM | 1 |
| Villamandos Nicás, V | 1 |
| Cancelo Suárez, P | 1 |
| del Portillo Rubí, A | 1 |
| Guillem Ares, E | 1 |
| Prada Mínguez, A | 1 |
| Sanz de la Fuente, H | 1 |
| Tsacopoulos, M | 1 |
| Levy, S | 1 |
| Bear, R | 1 |
| Goldstein, M | 1 |
| Phillipson, E | 1 |
| Ho, M | 1 |
| Hammeke, M | 1 |
| Feldman, R | 1 |
| Handelsman, S | 1 |
| Halperin, M | 1 |
| Gökhan, N | 1 |
| Gökçe, S | 1 |
| Wichser, J | 1 |
| Kazemi, H | 1 |
| Liddell, NE | 1 |
| Maren, TH | 2 |
| Lee, CA | 1 |
| Stroot, VR | 1 |
| Schaper, CA | 1 |
| de Frutos Herranz, M | 2 |
| García Garcia, JA | 1 |
| Aguado Matorras, A | 1 |
| Barth, J | 1 |
| Schatz, H | 1 |
| Charney, AN | 1 |
| Wagner, JD | 1 |
| Birnbaum, GJ | 1 |
| Johnstone, JN | 1 |
| Sharp, JT | 1 |
| Druz, WS | 1 |
| D'Souza, V | 1 |
| Diamond, E | 1 |
| Kuijpers, W | 1 |
| Bonting, SL | 1 |
| Waite, LC | 1 |
| Volkert, WA | 1 |
| Kenny, AD | 1 |
| Kellerhals, B | 1 |
| Guyatt, AR | 1 |
| Yu, CJ | 1 |
| Lutherer, B | 1 |
| Otis, AB | 1 |
| Lawin, P | 1 |
| Ellison, AC | 1 |
| Aguedo Matorras, A | 1 |
| Kurtzman, NA | 1 |
| Eisterer, H | 1 |
| Riedel, W | 1 |
| Richet, G | 1 |
| Hagege, J | 1 |
| Gabe, M | 1 |
| Bertrand, A | 1 |
| Janbon, F | 1 |
| Callis, A | 1 |
| Milane, J | 1 |
| Sawitsky, A | 1 |
| Cheung, WH | 1 |
| Seifter, E | 1 |
| Severinghaus, JW | 1 |
| Cotev, S | 1 |
| Glauser, EM | 1 |
| Glauser, SC | 1 |
| Marx, HH | 1 |
| Helbig, D | 1 |
1 review available for acetazolamide and Acidosis, Respiratory
| Article | Year |
|---|---|
[Disorders of acid-base equilibrium: differential diagnosis and therapy].
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Blood Gas Analysis | 1968 |
2 trials available for acetazolamide and Acidosis, Respiratory
| Article | Year |
|---|---|
Arterial [H+] and the ventilatory response to hypoxia in humans: influence of acetazolamide-induced metabolic acidosis.
Topics: Acetazolamide; Acidosis, Respiratory; Bicarbonates; Carbon Dioxide; Female; Humans; Hyperoxia; Hypox | 2010 |
Effects of acute and chronic acetazolamide on resting ventilation and ventilatory responses in men.
Topics: Acetazolamide; Acidosis, Respiratory; Adult; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibi | 1993 |
44 other studies available for acetazolamide and Acidosis, Respiratory
| Article | Year |
|---|---|
Normoxic induction of cerebral HIF-1alpha by acetazolamide in rats: role of acidosis.
Topics: Acetazolamide; Acidosis, Respiratory; Altitude Sickness; Animals; Carbonic Anhydrase Inhibitors; Cel | 2009 |
The importance of identifying the association between metabolic alkalosis and respiratory acidosis.
Topics: Acetazolamide; Acidosis, Respiratory; Alkalosis; Bicarbonates; Furosemide; Humans; Obesity Hypoventi | 2012 |
Respiratory and renal effects of a carbonic anhydrase inhibitor (diamox) on acid-base balance in normal man and in patients with respiratory acidosis.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Carbonic Anhydrase Inhibitors | 1955 |
[Diamox therapy of respiratory acidosis].
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Diuretics; Hydro-Lyases | 1956 |
[Therapy of pulmonary empyema connected with chronic respiratory acidosis].
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Aminophylline; Chronic Disease; Empyema; Empyema, Pl | 1957 |
The effect of acetazolamide on arterial carbon dioxide tension in respiratory acidosis: a preliminary report.
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Carbon Dioxide; Humans | 1957 |
The treatment of respiratory acidosis with a potent carbonic anhydrase inhibitor (dichlorphenamide).
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Hum | 1958 |
Effect of diamox on plasma and urine acid-base composition during chronic respiratory acidosis.
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Base Composition; Cell Respiration; Humans; Respirat | 1959 |
[Treatment of respiratory acidosis in advanced pulmonary emphysema].
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Emphysema; Humans; Pulmonary Emphysema | 1959 |
[PATHOPHYSIOLOGY AND THERAPY OF PULMONARY EMPHYSEMA WITH RESPIRATORY ACIDOSIS AND COR PULMONALE].
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Anti-Bacterial Agents; Cardiac Glycosides; Exercise | 1963 |
Effects of the carbonic anhydrase inhibitor "6063" (diamox) on respiration and electrolyte metabolism of patients with respiratory acidosis.
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Carbonic Anhydrase Inhibitors; Diuretics; Electrolyt | 1955 |
Acetazolamide teratogenesis: association of maternal respiratory acidosis and ectrodactyly in C57BL/6J mice.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Acidosis, Respiratory; Animals; Carbon Dioxide; Dose-Res | 1984 |
Acetazolamide teratogenesis: interaction of maternal metabolic and respiratory acidosis in the induction of ectrodactyly in C57BL/6J mice.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Acidosis; Acidosis, Respiratory; Animals; Carbon Dioxide | 1984 |
Effects of acetazolamide on ionic composition of cisternal fluid during acute respiratory acidosis.
Topics: Acetazolamide; Acidosis, Respiratory; Animals; Bicarbonates; Dogs; Hydrogen-Ion Concentration; Osmol | 1984 |
Effects of carbonic anhydrase inhibition on the acid base status in lamprey and trout.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Respiratory; Animals; Blood Gas Analysis; Carbonic A | 1995 |
Intracellular pH recovery during respiratory acidosis in perfused hearts.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Acidosis, Respiratory; Amiloride; A | 1994 |
Effects of carbonic anhydrase inhibition on ventilation-perfusion matching in the dog lung.
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Animals; Benzolamide; Blood Pressure; Carbon Dioxide | 1993 |
[Efficacy of acetazolamide treatment of patients with hypercapnia and superimposed metabolic alkalosis].
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Respiratory; Adrenal Cortex Hormones; Aged; Aged, 80 | 1997 |
Intraretinal acid-base studies using pH glass microelectrodes: effect of respiratory and metabolic acidosis and alkalosis on inner-retinal pH.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Ammonium Chloride; | 1976 |
Effect of metabolic alkalosis on respiratory function in patients with chronic obstructive lung disease.
Topics: Acetazolamide; Acidosis, Respiratory; Aged; Alkalosis; Ammonium Chloride; Bicarbonates; Blood Gas An | 1977 |
Influence of hypercapnia on intraocular pressure in rabbits.
Topics: Acetazolamide; Acidosis, Respiratory; Animals; Blood Pressure; Carbon Dioxide; Carbonates; Hydrogen- | 1975 |
CSF bicarbonate regulation in respiratory acidosis and alkalosis.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis, Respiratory; Ammonia; Ammoni | 1975 |
CO2 retention as a basis for increased toxicity of salicylate with acetazolamide: avoidance of increased toxicity with benzolamide.
Topics: Acetazolamide; Acidosis, Respiratory; Alkalies; Animals; Benzolamide; Carbon Dioxide; Hydrogen-Ion C | 1975 |
What to do when acid-base problems hang in the balance.
Topics: Acetazolamide; Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Adult; Alkalosis; Alkalosis, Re | 1975 |
[Treatment of hypercapnic acidosis with acetazolamide and Tham].
Topics: Acetazolamide; Acidosis, Respiratory; Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Femal | 1975 |
[The indications for acetazolamide].
Topics: Acetazolamide; Acidosis, Respiratory; Alkalosis; Humans; Hypercapnia; Respiratory Insufficiency | 1992 |
Functional role of carbonic anhydrase in intestinal electrolyte transport.
Topics: Acetazolamide; Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Biological Transport; Carbon | 1986 |
Effect of metabolic acidosis upon sleep apnea.
Topics: Acetazolamide; Acidosis, Respiratory; Administration, Oral; Adult; Aged; Alkalosis, Respiratory; Fem | 1985 |
The cochlear potentials. II. The nature of the cochlear endolymphatic resting potential.
Topics: Acetazolamide; Acidosis, Respiratory; Adenosine Triphosphatases; Animals; Biological Transport, Acti | 1970 |
Inhibition of bone resorption by acetazolamide in the rat.
Topics: Acetazolamide; Acidosis, Respiratory; Analysis of Variance; Animals; Bone Resorption; Calcium; Calci | 1970 |
[Round table discussion of the treatment of respiratory insufficiency. Madrid, 22 October 1965].
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Respiratory; Adrenal Cortex Hormones; Aminobutyrates | 1966 |
Pharmacology of perilymph production.
Topics: Acetazolamide; Acidosis, Respiratory; Adenosine Triphosphate; Albumins; Animals; Dextrans; Dihydroer | 1974 |
Studies on alveolar-mixed venous CO 2 and O 2 gradients in the rebreathing dog lung.
Topics: Acetazolamide; Acidosis, Respiratory; Animals; Arteries; Bicarbonates; Blood Flow Velocity; Blood Ga | 1973 |
The effects of metabolic alterations on teratogenesis.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Acidosis; Acidosis, Respiratory; Alloxan; Animals; Birth | 1972 |
[Indications for THAM in hypercapnic acidosis].
Topics: Acetazolamide; Acidosis, Respiratory; Drug Synergism; Humans; Hypercapnia; Tromethamine | 1971 |
Relationship of extracellular volume and CO2 tension to renal bicarbonate reabsorption.
Topics: Acetazolamide; Acidosis, Respiratory; Animals; Arteries; Bicarbonates; Blood Pressure; Carbon Dioxid | 1970 |
[Alkalotic metabolic disorders during intensive therapy].
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis; Blood Gas Analysis; Diagnosi | 1970 |
[Correlation between bicarbonate transfer and morphology of tubular cells distal to Henle's loop in the rat].
Topics: Absorption; Acetazolamide; Acidosis, Respiratory; Animals; Bicarbonates; Diuresis; Kidney Tubules; O | 1970 |
[Use of diuretics in the course of acute respiratory insufficiency in chronic broncho-pulmonary diseases: apropos of a study of clopamide, ethacrynic acid and acetazolamide].
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Respiratory; Amides; Bronchial Diseases; Clopamide; | 1968 |
The effect of pH on the distribution of bilirubin in peripheral blood, cerebrospinal fluid, and fat tissues.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Adipose Tissue; Alkalosis; Am | 1968 |
Carbonic acidosis and cerebral vasodilation after Diamox.
Topics: Acetazolamide; Acidosis, Respiratory; Animals; Blood Gas Analysis; Brain; Carbon Dioxide; Cerebrovas | 1968 |
The role of acidosis in the etiology of pulmonary emphysema.
Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Ammonium Chloride; Animals; Animals, Newborn; Bicarb | 1969 |
[Shifts of the acid-base equilibrium in chronic pulmonary insufficiency].
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Respiratory; Digitoxin; Furosemide; Humans; Hydrogen | 1965 |
[Special problems of burns in childhood].
Topics: Acetazolamide; Acidosis, Respiratory; Bandages; Body Weight; Burns; Child; Child, Preschool; Chlorpr | 1966 |