acetazolamide has been researched along with Acidosis, Renal Tubular in 34 studies
Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Acidosis, Renal Tubular: A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 46-year-old man with hypokalemic periodic paralysis (HypoPP) and diabetes mellitus (DM) had worsened muscle weakness after acetazolamide (ACZ) treatment." | 7.71 | Acetazolamide-induced muscle weakness in hypokalemic periodic paralysis. ( Ichikawa, Y; Igarashi, O; Ikeda, K; Iwasaki, Y; Kinoshita, M; Satoyoshi, E; Yabuki, D, 2002) |
| "The effect of the carbonic anhydrase inhibitor acetazolamide on intraocular pressure was studied in two patients with carbonic anhydrase II deficiency and in six control subjects." | 7.67 | Failure of acetazolamide to decrease intraocular pressure in patients with carbonic anhydrase II deficiency. ( Dodgson, SJ; Krupin, T; Sly, WS; Whyte, MP, 1985) |
| "Hyperphosphatemic familial tumoral calcinosis (HFTC) is an uncommon disease characterized by periarticular calcifications produced by the deposition of amorphous extraosseous calcifications of hydroxyapatite." | 5.35 | Familial tumoral calcinosis caused by a novel FGF23 mutation: response to induction of tubular renal acidosis with acetazolamide and the non-calcium phosphate binder sevelamer. ( Lammoglia, JJ; Mericq, V, 2009) |
| "A 46-year-old man with hypokalemic periodic paralysis (HypoPP) and diabetes mellitus (DM) had worsened muscle weakness after acetazolamide (ACZ) treatment." | 3.71 | Acetazolamide-induced muscle weakness in hypokalemic periodic paralysis. ( Ichikawa, Y; Igarashi, O; Ikeda, K; Iwasaki, Y; Kinoshita, M; Satoyoshi, E; Yabuki, D, 2002) |
| " His mother had glaucoma and had been treated during pregnancy with oral acetazolamide, a carbonic anhydrase inhibitor." | 3.71 | Transient renal tubular acidosis in a neonate following transplacental acetazolamide. ( Azuma, E; Higashigawa, M; Komada, Y; Mukouhara, R; Ozawa, H; Shindo, K, 2001) |
| "The effect of the carbonic anhydrase inhibitor acetazolamide on intraocular pressure was studied in two patients with carbonic anhydrase II deficiency and in six control subjects." | 3.67 | Failure of acetazolamide to decrease intraocular pressure in patients with carbonic anhydrase II deficiency. ( Dodgson, SJ; Krupin, T; Sly, WS; Whyte, MP, 1985) |
| "Hyperphosphatemic familial tumoral calcinosis (HFTC) is an uncommon disease characterized by periarticular calcifications produced by the deposition of amorphous extraosseous calcifications of hydroxyapatite." | 1.35 | Familial tumoral calcinosis caused by a novel FGF23 mutation: response to induction of tubular renal acidosis with acetazolamide and the non-calcium phosphate binder sevelamer. ( Lammoglia, JJ; Mericq, V, 2009) |
| "Distal renal tubular acidosis is frequently associated with hypercalciuria." | 1.29 | Renal acidification in children with idiopathic hypercalciuria. ( Bonilla-Felix, M; Vehaskari, VM; Villegas-Medina, O, 1994) |
| "A state of renal tubular acidosis has been produced in rats by the administration of sodium maleate or acetazolamide (proximal tubular acidosis) and of lithium chloride of amiloride (distal tubular acidosis)." | 1.26 | [Urinary-blood delta PCO2 in renal tubular acidosis (author's transl)]. ( Aubert, E; Guignard, JP, 1980) |
| "Acetazolamide was given to 11 patients but failed to increase fractional potassium excretion to normal." | 1.26 | Hyperkalemic distal renal tubular acidosis associated with obstructive uropathy. ( Arruda, JA; Batlle, DC; Kurtzman, NA, 1981) |
| "The diagnosis of transient renal tubular acidosis was made in a 16 months old boy." | 1.26 | A case of transient renal tubular acidosis type 1,4 hybrid RTA: a study of the pathophysiologic characteristics of the acidification defect. ( Donckerwolcke, RA; Valk, C; van Stekelenburg, GJ; van Wijngaarden-Penterman, MJ, 1979) |
| "These children had rickets and renal tubular acidosis." | 1.25 | Renal tubular acidosis and skeletal demineralization in patients on long-term anticonvulsant therapy. ( Fujieda, K; Matsuda, I; Nagai, B; Shida, N; Takekoshi, Y, 1975) |
| "A proximal renal tubular acidosis (RTA) is the mechanism underlying the systemic acidosis found in vitamin D deficiency rickets." | 1.25 | Proximal renal tubular acidosis in vitamin D deficiency rickets. ( Manderlier, T; Vainsel, M; Vis, HL, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (76.47) | 18.7374 |
| 1990's | 3 (8.82) | 18.2507 |
| 2000's | 4 (11.76) | 29.6817 |
| 2010's | 1 (2.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mugundhan, K | 1 |
| Vasif, MC | 1 |
| Prakash, G | 1 |
| Balamurugan, N | 1 |
| Sivakumar, KG | 1 |
| Bakthavatchalam, B | 1 |
| Lammoglia, JJ | 1 |
| Mericq, V | 1 |
| Ikeda, K | 1 |
| Iwasaki, Y | 1 |
| Kinoshita, M | 1 |
| Yabuki, D | 1 |
| Igarashi, O | 1 |
| Ichikawa, Y | 1 |
| Satoyoshi, E | 1 |
| Raghunand, N | 1 |
| Howison, C | 1 |
| Sherry, AD | 1 |
| Zhang, S | 1 |
| Gillies, RJ | 1 |
| WEBSTER, GD | 1 |
| HUTH, EJ | 1 |
| ELKINTON, JR | 1 |
| McCANCE, RA | 1 |
| CANNON, PJ | 1 |
| HEINEMANN, HO | 1 |
| STASON, WB | 1 |
| LARAGH, JH | 1 |
| Mengele, K | 1 |
| Rodriguez Soriano, J | 1 |
| Boichis, H | 1 |
| Stark, H | 1 |
| Edelmann, CM | 1 |
| Aubert, E | 1 |
| Guignard, JP | 1 |
| Maisey, DN | 1 |
| Brown, RD | 1 |
| Ishitsu, T | 1 |
| Matsuda, I | 2 |
| Seino, Y | 1 |
| Kann, H | 1 |
| Al-Bander, HA | 1 |
| Weiss, RA | 1 |
| Humphreys, MH | 1 |
| Morris, RC | 1 |
| Batlle, DC | 1 |
| Arruda, JA | 1 |
| Kurtzman, NA | 1 |
| Bonilla-Felix, M | 2 |
| Villegas-Medina, O | 1 |
| Vehaskari, VM | 1 |
| Ozawa, H | 1 |
| Azuma, E | 1 |
| Shindo, K | 1 |
| Higashigawa, M | 1 |
| Mukouhara, R | 1 |
| Komada, Y | 1 |
| Donckerwolcke, RA | 2 |
| Valk, C | 1 |
| van Wijngaarden-Penterman, MJ | 1 |
| van Stekelenburg, GJ | 2 |
| Winsnes, A | 1 |
| Monn, E | 1 |
| Stokke, O | 1 |
| Feyling, T | 1 |
| Takekoshi, Y | 1 |
| Shida, N | 1 |
| Fujieda, K | 1 |
| Nagai, B | 1 |
| Vainsel, M | 1 |
| Manderlier, T | 1 |
| Vis, HL | 1 |
| Alon, U | 1 |
| Hellerstein, S | 1 |
| Warady, BA | 1 |
| Obana, M | 1 |
| Higashi, F | 1 |
| Kato, E | 1 |
| Krupin, T | 2 |
| Sly, WS | 2 |
| Whyte, MP | 2 |
| Dodgson, SJ | 1 |
| Sundaram, V | 1 |
| Ashouri, OS | 1 |
| Fillastre, JP | 1 |
| Ardaillou, R | 1 |
| Richet, G | 1 |
| Hodler, J | 1 |
| Gofman, L | 1 |
| Sinkó, O | 1 |
| Tiddens, HA | 1 |
| Schneegans, F | 1 |
| Haarscher, A | 1 |
| el-Majjati, A | 1 |
| Alleyne, GA | 1 |
| Gregory, DH | 1 |
| Walker, FE | 1 |
| Eichenholz, A | 1 |
| Arnold, JE | 1 |
| Healy, JK | 1 |
| Yamaguchi, H | 1 |
| Fujii, J | 1 |
| Kurihara, H | 1 |
| Kimura, K | 1 |
| Ikeda, M | 1 |
2 reviews available for acetazolamide and Acidosis, Renal Tubular
| Article | Year |
|---|---|
Primary distal renal tubular acidosis as a result of a gradient defect.
Topics: Acetazolamide; Acidosis, Renal Tubular; Carbon Dioxide; Diuretics; Furosemide; Humans; Hydrogen-Ion | 1996 |
[Drug-induced renal tubular acidosis].
Topics: Acetazolamide; Acidosis, Renal Tubular; Amphotericin B; Animals; Cadmium; Heparin; Humans; Indometha | 1985 |
1 trial available for acetazolamide and Acidosis, Renal Tubular
| Article | Year |
|---|---|
[Renal response to alkaline overload during chronic renal insufficiency].
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Renal Tubular; Bicarbonates; Clinical Trials as Topi | 1968 |
31 other studies available for acetazolamide and Acidosis, Renal Tubular
| Article | Year |
|---|---|
Hypokalemic Paralysis in Sjogren's Syndrome Secondary to Renal Tubular Acidosis.
Topics: Acetazolamide; Acidosis, Renal Tubular; Adult; Female; Humans; Hypokalemia; Immunosuppressive Agents | 2016 |
Familial tumoral calcinosis caused by a novel FGF23 mutation: response to induction of tubular renal acidosis with acetazolamide and the non-calcium phosphate binder sevelamer.
Topics: Acetazolamide; Acidosis, Renal Tubular; Calcinosis; Chelating Agents; Child, Preschool; Diuretics; D | 2009 |
Acetazolamide-induced muscle weakness in hypokalemic periodic paralysis.
Topics: Acetazolamide; Acidosis, Renal Tubular; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Di | 2002 |
Renal and systemic pH imaging by contrast-enhanced MRI.
Topics: Acetazolamide; Acidosis, Renal Tubular; Animals; Contrast Media; Female; Gadolinium; Gadolinium DTPA | 2003 |
The renal excretion of hydrogen ion in renal tubular acidosis. II. Quantitative response to the carbonic anhydrase inhibitor, acetazolamide.
Topics: Acetazolamide; Acidosis, Renal Tubular; Carbonic Anhydrase Inhibitors; Humans; Hydrogen; Kidney Func | 1960 |
ETHACRYNIC ACID: EFFECTIVENESS AND MODE OF DIURETIC ACTION IN MAN.
Topics: Acetazolamide; Acidosis; Acidosis, Renal Tubular; Alkalosis; Ascites; Carbonic Anhydrase Inhibitors; | 1965 |
[Physiopathology of renal tubular acidosis].
Topics: Acetazolamide; Acidosis, Renal Tubular; Adult; Ammonium Chloride; Bicarbonates; Dehydration; Female; | 1966 |
Proximal renal tubular acidosis. A defect in bicarbonate reabsorption with normal urinary acidification.
Topics: Acetazolamide; Acidosis, Renal Tubular; Amino Acids; Ammonium Chloride; Bicarbonates; Blood Urea Nit | 1967 |
[Urinary-blood delta PCO2 in renal tubular acidosis (author's transl)].
Topics: Acetazolamide; Acidosis, Renal Tubular; Amiloride; Animals; Carbon Dioxide; Chlorides; Disease Model | 1980 |
Acetazolamide and symptomatic metabolic acidosis in mild renal failure.
Topics: Acetazolamide; Acidosis, Renal Tubular; Aged; Female; Humans; Kidney Failure, Chronic; Male | 1981 |
Anticonvulsant-induced rickets associated with renal tubular acidosis and normal level of serum 1,25-dihydroxyvitamin D.
Topics: Acetazolamide; Acidosis, Renal Tubular; Anticonvulsants; Calcitriol; Child; Female; Humans; Phenobar | 1981 |
Dysfunction of the proximal tubule underlies maleic acid-induced type II renal tubular acidosis.
Topics: Acetazolamide; Acidosis, Renal Tubular; Animals; Bicarbonates; Diuresis; Dogs; Female; Glomerular Fi | 1982 |
Hyperkalemic distal renal tubular acidosis associated with obstructive uropathy.
Topics: Acetazolamide; Acidosis, Renal Tubular; Aged; Aldosterone; Diagnosis, Differential; Glomerular Filtr | 1981 |
Renal acidification in children with idiopathic hypercalciuria.
Topics: Acetazolamide; Acidosis, Renal Tubular; Adolescent; Arginine; Calcium; Child; Child, Preschool; Fema | 1994 |
Transient renal tubular acidosis in a neonate following transplacental acetazolamide.
Topics: Acetazolamide; Acidosis, Renal Tubular; Carbonic Anhydrase Inhibitors; Diuretics; Female; Glaucoma; | 2001 |
A case of transient renal tubular acidosis type 1,4 hybrid RTA: a study of the pathophysiologic characteristics of the acidification defect.
Topics: Acetazolamide; Acidosis, Renal Tubular; Acids; Bicarbonates; Humans; Hydrogen-Ion Concentration; Inf | 1979 |
Congenital persistent proximal type renal tubular acidosis in two brothers.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Renal Tubular; Bicarbonates; Child; Dental Enamel; E | 1979 |
Renal tubular acidosis and skeletal demineralization in patients on long-term anticonvulsant therapy.
Topics: Acetazolamide; Acidosis, Renal Tubular; Ammonium Chloride; Anticonvulsants; Bicarbonates; Bone and B | 1975 |
Proximal renal tubular acidosis in vitamin D deficiency rickets.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Renal Tubular; Adolescent; Bicarbonates; Calcium; Ca | 1975 |
Oral acetazolamide in the assessment of (urine-blood) PCO2.
Topics: Acetazolamide; Acidosis, Renal Tubular; Administration, Oral; Adolescent; Bicarbonates; Biological T | 1991 |
Failure of acetazolamide to decrease intraocular pressure in patients with carbonic anhydrase II deficiency.
Topics: Acetazolamide; Acidosis, Renal Tubular; Adult; Brain Diseases; Calcinosis; Carbonic Anhydrases; Fema | 1985 |
Positive renal response to intravenous acetazolamide in patients with carbonic anhydrase II deficiency.
Topics: Acetazolamide; Acidosis, Renal Tubular; Adult; Carbonic Anhydrases; Female; Humans; Hydrogen-Ion Con | 1985 |
Hyperkalemic distal renal tubular acidosis and selective aldosterone deficiency. Combination in a patient with lead nephropathy.
Topics: Acetazolamide; Acidosis, Renal Tubular; Aldosterone; Electrolytes; Female; Fludrocortisone; Furosemi | 1985 |
[Bicarbonate reabsorption and carbonic anhydrase activity in diseased kidneys in humans].
Topics: Acetazolamide; Acidosis, Renal Tubular; Anorexia Nervosa; Bicarbonates; Carbon Dioxide; Carbonic Anh | 1963 |
Renal tubular acidosis in an adult.
Topics: Acetazolamide; Acidosis, Renal Tubular; Adult; Age Factors; Carbonates; Carbonic Anhydrases; Citrate | 1969 |
A case of bicarbonate-losing renal tubular acidosis with defective carboanhydrase activity.
Topics: Acetazolamide; Acidosis, Renal Tubular; Ammonium Chloride; Bicarbonates; Carbon Dioxide; Carbonic An | 1970 |
[A case of renal acidosis with a 7-years follow-up].
Topics: Acetazolamide; Acidosis, Renal Tubular; Bicarbonates; Calcium; Humans; Hydrogen-Ion Concentration; I | 1970 |
Concentrations of metabolic intermediates in kidneys of rats with metabolic acidosis.
Topics: Acetazolamide; Acidosis, Renal Tubular; Ammonium Chloride; Animals; Aspartic Acid; Citrates; Glucone | 1968 |
Secondary proximal tubular acidosis.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Renal Tubular; Adult; Aged; Bicarbonates; Blood Chem | 1969 |
Hyperkalemia, hypertension and systemic acidosis without renal failure associated with a tubular defect in potassium excretion.
Topics: Acetazolamide; Acidosis, Renal Tubular; Adolescent; Adult; Aminohippuric Acids; Bicarbonates; Blood | 1969 |
A case of renal tubular acidosis with an abnormally high plasma renin activity.
Topics: 17-Hydroxycorticosteroids; Acetazolamide; Acidosis, Renal Tubular; Ammonium Chloride; Bicarbonates; | 1969 |