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acetazolamide and Absence Seizure

acetazolamide has been researched along with Absence Seizure in 68 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"To our knowledge, this represents one of the mildest described presentations of nonepileptic GLUT1 DS consisting of acetazolamide-responsive EA without seizures or baseline neurological examination abnormalities."8.98Acetazolamide-responsive Episodic Ataxia Without Baseline Deficits or Seizures Secondary to GLUT1 Deficiency: A Case Report and Review of the Literature. ( Mikati, MA; Tchapyjnikov, D, 2018)
"To our knowledge, this represents one of the mildest described presentations of nonepileptic GLUT1 DS consisting of acetazolamide-responsive EA without seizures or baseline neurological examination abnormalities."4.98Acetazolamide-responsive Episodic Ataxia Without Baseline Deficits or Seizures Secondary to GLUT1 Deficiency: A Case Report and Review of the Literature. ( Mikati, MA; Tchapyjnikov, D, 2018)
" We examined acetazolamide effects in G1D motivated by several longstanding and recent observations: First, the electrographic spike-waves characteristic of absence seizures often resemble those of G1D and, since the 1950s, they have occasionally been treated successfully with acetazolamide, well before G1D was segregated from absence epilepsy as a distinct syndrome."4.31A concise study of acetazolamide in glucose transporter type 1 deficiency (G1D) epilepsy. ( Avila, A; Málaga, I; Park, JY; Pascual, JM; Primeaux, S, 2023)
" The history of this patient with prolonged acidosis is analyzed, and the role of metabolic changes induced by H(2) 15O-PET with acetazolamide challenge is reviewed."3.72Metabolic changes after H(2) 15O-positron emission tomography with acetazolamide in a patient with moyamoya disease: case report and review of previous cases. ( Keller, E; Khan, N; Muroi, C; Pangalu, A; Yonekawa, Y, 2003)
" Cyclic sulfate 2, like topiramate and phenytoin, did not interfere with seizures induced by pentylenetetrazole, bicucculine, picrotoxin, and strychnine; also, 2 was not active in diverse in vitro receptor binding and uptake assays."3.70Structure-activity studies on anticonvulsant sugar sulfamates related to topiramate. Enhanced potency with cyclic sulfate derivatives. ( Costanzo, MJ; Greco, MN; Maryanoff, BE; Nortey, SO; Ortegon, MP; Schupsky, JJ; Shank, RP; Vaught, JL, 1998)
"The kindling of amygldaloid and cortical seizures in cats was used to study the prophylactic effects of phenobarbital, phenytoin, ethosuximide, acetazolamide, and dexamethason."3.65Pharmacological prophylaxis against the development of kindled amygdaloid seizures. ( Kutt, H; Louis, S; Newman, SM; Turner, IM, 1977)
" Phenobarbital is usually given as well to prevent grand mal seizures."3.64Treatment of epilepsy. ( BAILEY, AA, 1963)
"Catamenial epilepsy affects approximately one-third of women with epilepsy."2.42Catamenial epilepsy: pathophysiology, diagnosis, and management. ( Falcone, T; Foldvary-Schaefer, N, 2003)
"Furthermore, time dependent seizure protection capability of the most potent compound was also evaluated."1.48Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation. ( Angeli, A; Bua, S; Kumari, S; Mishra, CB; Supuran, CT; Tiwari, M, 2018)
"The maximal electroshock seizure (MES) test performed on mice showed a good anticonvulsant activity for some compounds which protected the mice against convulsions in the 50-62."1.35Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation. ( Dogné, JM; Frankart, A; Masereel, B; Rolin, S; Scozzafava, A; Supuran, CT; Thiry, A; Vullo, D; Wouters, J, 2008)
"The time from exposure to the onset of seizure (clonic-tonic convulsion) was recorded for each animal according to behavioral observation."1.32[Effect of acetazolamide on the latency of hyperbaric oxygen-induced convulsion]. ( Guo, MZ; Huang, JL; Jiang, CL; Lian, QL; Ma, YW; Sun, XJ; Xu, JP, 2004)
"In acetazolamide-treated animals, no HBO, induced vasoconstricton was observed and striatal blood flow increased by 53 +/- 18% within 10 min of hyperbaric exposure."1.32[Nitric oxide and carbon dioxide in neurotoxicity induced by oxygen under pressure]. ( Demchenko, IT; Gutsaeva, DR; Kostkin, VB; Moskvin, AN; Zhiliaev, SIu, 2004)
"Topiramate is a relatively new antiepileptic drug with several putative anticonvulsant mechanisms."1.31A comparison of topiramate and acetazolamide on seizure duration and paired-pulse inhibition in the dentate gyrus of the rat. ( Stringer, JL, 2000)
"In the maximal electroshock seizure test, orally at 2 h in mice, 1 had an ED50 of 39 mg/kg."1.27Anticonvulsant O-alkyl sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate and related compounds. ( Dodgson, SP; Gardocki, JF; Maryanoff, BE; Nortey, SO; Shank, RP, 1987)
" In order to test the validity of FEAD as an absence seizure model, the present experiments determined dose-response relationships for the suppression of FEAD by six antiepileptic drugs with established clinical profiles."1.26Flash-evoked afterdischarge in rat as a model of the absence seizure: dose-response studies with therapeutic drugs. ( Burnham, WM; King, GA; Livingston, KE, 1980)

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199046 (67.65)18.7374
1990's5 (7.35)18.2507
2000's8 (11.76)29.6817
2010's6 (8.82)24.3611
2020's3 (4.41)2.80

Authors

AuthorsStudies
Maryanoff, BE2
Nortey, SO2
Gardocki, JF1
Shank, RP2
Dodgson, SP1
Costanzo, MJ1
Greco, MN1
Schupsky, JJ1
Ortegon, MP1
Vaught, JL1
Masereel, B2
Rolin, S2
Abbate, F1
Scozzafava, A2
Supuran, CT5
Thiry, A1
Vullo, D1
Frankart, A1
Dogné, JM1
Wouters, J1
Mishra, CB3
Kumari, S3
Angeli, A3
Monti, SM2
Buonanno, M2
Tiwari, M3
Bua, S2
Finsterer, J1
Scorza, FA1
Málaga, I1
Avila, A1
Primeaux, S1
Park, JY1
Pascual, JM1
Pospelov, AS1
Ala-Kurikka, T1
Kurki, S1
Voipio, J1
Kaila, K1
Tchapyjnikov, D1
Mikati, MA1
Wennberg, R1
Maurice, C1
Carlen, PL1
Garcia Dominguez, L1
Hamidi, S1
D'Antuono, M1
Avoli, M1
Muroi, C1
Yonekawa, Y1
Khan, N1
Pangalu, A1
Keller, E1
Fujiwara-Tsukamoto, Y1
Isomura, Y1
Nambu, A1
Takada, M1
KOCH, A1
WOODBURY, DM1
BAILEY, AA1
WADA, T1
TAKASE, M1
FUKUSHIMA, Y1
POIRE, R1
ROYER, P1
DEGRAEVE, M1
RUSTIN, C1
JABBOUR, JT1
MILLICHAP, JG3
JONES, JD1
RUDIS, BP1
STEINSCHNEIDER, A1
GINSBERG, T1
GEORGE, ED1
LIPTON, EL1
MIZUNO, T1
MACGREGOR, M1
JONGMANS, JW1
CASTILLO, LS2
TIMIRAS, PS2
GROSS, MD1
WILSON, WC1
CRAIG, WS1
MACKINNON, JM1
ZAKHARIIA, EA1
ZAPADNIUK, VI1
KIORBOE, E1
Foldvary-Schaefer, N1
Falcone, T1
Huang, JL1
Ma, YW1
Lian, QL1
Xu, JP1
Jiang, CL1
Guo, MZ1
Sun, XJ1
Gutsaeva, DR1
Moskvin, AN1
Zhiliaev, SIu1
Kostkin, VB1
Demchenko, IT1
Wilder, BJ1
Bruni, J1
Czuczwar, SJ1
Turski, L1
Turski, W1
Kleinrok, Z1
Wood, CD1
Lebedev, BV1
Morozova, NA1
Znamenskaia, EI1
King, GA1
Burnham, WM1
Livingston, KE1
Mihály, A1
Bencsik, K1
Nógrádi, A1
Alzuet, G1
Ferrer, S1
Borrás, J1
Sorenson, JR1
Tallian, KB1
Nahata, MC1
Tsao, CY1
Stringer, JL1
Browning, RA1
Hoffmann, WE1
Simonton, RL1
Ito, T1
Hori, M1
Yoshida, K1
Shimizu, M1
Turner, IM1
Newman, SM1
Louis, S2
Kutt, H2
Tarr, RW1
Johnson, DW1
Rutigliano, M1
Hecht, ST1
Pentheny, S1
Jungreis, CA1
Horton, JA1
Yonas, H1
Hagberg, B1
Hansson, O1
Hooshmand, H1
Suter, CG1
Mennear, JH2
Rudzik, AD2
Göres, E1
Kurze, G1
Oehme, P1
Lancaster, JR1
Levinson, MR1
Addy, DP1
Caspers, H1
Speckmann, EJ1
Simmich, W1
Zoll, WR1
Tchicaloff, M1
Halpern, LM1
Ward, AA1
Nair, V1
Bau, D1
Koslow, SH1
Roth, LJ1
Ferngren, H2
Paalzow, L2
Weinreich, D1
Clark, LD1
Yoshikawa, H1
Rauh, CE1
Gray, WD1
Tanimukai, H1
Inui, M1
Hariguchi, S1
Kaneko, Z1

Reviews

4 reviews available for acetazolamide and Absence Seizure

ArticleYear
Acetazolamide-responsive Episodic Ataxia Without Baseline Deficits or Seizures Secondary to GLUT1 Deficiency: A Case Report and Review of the Literature.
    The neurologist, 2018, Volume: 23, Issue:1

    Topics: Acetazolamide; Ataxia; Carbohydrate Metabolism, Inborn Errors; Child, Preschool; Glucose Transporter

2018
Catamenial epilepsy: pathophysiology, diagnosis, and management.
    Neurology, 2003, Sep-01, Volume: 61, Issue:6 Suppl 2

    Topics: Acetazolamide; Adolescent; Adult; Animals; Anticonvulsants; Brain Edema; Bromides; Contraceptives, O

2003
Role of the ketogenic diet in children with intractable seizures.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:3

    Topics: Acetazolamide; Anticonvulsants; Avitaminosis; Child; Child, Preschool; Dehydration; Food-Drug Intera

1998
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
    Epilepsia, 1969, Volume: 10, Issue:2

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials

1969

Trials

1 trial available for acetazolamide and Absence Seizure

ArticleYear
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
    Epilepsia, 1969, Volume: 10, Issue:2

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials

1969

Other Studies

64 other studies available for acetazolamide and Absence Seizure

ArticleYear
Anticonvulsant O-alkyl sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate and related compounds.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Electroshock; Fructose; Kinet

1987
Structure-activity studies on anticonvulsant sugar sulfamates related to topiramate. Enhanced potency with cyclic sulfate derivatives.
    Journal of medicinal chemistry, 1998, Apr-09, Volume: 41, Issue:8

    Topics: Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Electroshock; Fruct

1998
Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties.
    Journal of medicinal chemistry, 2002, Jan-17, Volume: 45, Issue:2

    Topics: Acetazolamide; Animals; Anticonvulsants; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhyd

2002
Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:12

    Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; C

2008
Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment.
    Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6

    Topics: Animals; Anticonvulsants; Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; D

2017
Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation.
    Journal of medicinal chemistry, 2018, 04-12, Volume: 61, Issue:7

    Topics: Animals; Anticonvulsants; Benzene Derivatives; Carbonic Anhydrase Inhibitors; Convulsants; Dose-Resp

2018
Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Animals; Anticonvulsants; Benzenesulfonamides; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic

2018
If SARS-CoV-2 is blamed for causing meningoencephalitis, the virus must be detected in the CSF.
    Annals of agricultural and environmental medicine : AAEM, 2023, Mar-31, Volume: 30, Issue:1

    Topics: Acetazolamide; COVID-19; Humans; Male; Meningoencephalitis; SARS-CoV-2; Seizures

2023
A concise study of acetazolamide in glucose transporter type 1 deficiency (G1D) epilepsy.
    Epilepsia, 2023, Volume: 64, Issue:9

    Topics: Acetazolamide; Anticonvulsants; Epilepsy, Absence; Glucose Transporter Type 1; Humans; Seizures

2023
Carbonic anhydrase inhibitors suppress seizures in a rat model of birth asphyxia.
    Epilepsia, 2021, Volume: 62, Issue:8

    Topics: Acetazolamide; Acidosis; Animals; Asphyxia; Asphyxia Neonatorum; Carbonic Anhydrase Inhibitors; Huma

2021
Pilomotor seizures marked by infraslow activity and acetazolamide responsiveness.
    Annals of clinical and translational neurology, 2019, Volume: 6, Issue:1

    Topics: Acetazolamide; Adult; Anticonvulsants; Autoantibodies; Brain; Electroencephalography; Female; Humans

2019
On the contribution of KCC2 and carbonic anhydrase to two types of in vitro interictal discharge.
    Pflugers Archiv : European journal of physiology, 2015, Volume: 467, Issue:11

    Topics: Acetazolamide; Animals; CA3 Region, Hippocampal; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases;

2015
Metabolic changes after H(2) 15O-positron emission tomography with acetazolamide in a patient with moyamoya disease: case report and review of previous cases.
    Journal of neurosurgical anesthesiology, 2003, Volume: 15, Issue:2

    Topics: Acetazolamide; Acidosis; Adult; Blood Pressure; Carotid Arteries; Cerebral Angiography; Cerebral Rev

2003
Excitatory GABA input directly drives seizure-like rhythmic synchronization in mature hippocampal CA1 pyramidal cells.
    Neuroscience, 2003, Volume: 119, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetazolamide; Animals; Animals, Newborn; Anti-Ulcer Agents; A

2003
Effects of carbonic anhydrase inhibition of brain excitability.
    The Journal of pharmacology and experimental therapeutics, 1958, Volume: 122, Issue:3

    Topics: Acetazolamide; Brain; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Ni

1958
Treatment of epilepsy.
    Canadian Medical Association journal, 1963, Jun-29, Volume: 88

    Topics: Acetazolamide; Anticonvulsants; Automatism; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clon

1963
Diamox acetazolamide in treatment of the epileptics with frequent seizures or status epilepticus.
    Folia psychiatrica et neurologica japonica, 1961, Volume: 15

    Topics: Acetazolamide; Epilepsy; Seizures; Status Epilepticus

1961
[EXPERIMENTAL DETERMINATION OF ANTICONVULSANT PROPERTIES OF DICHLORPHENAMIDE BY ELECTROENCEPHALOGRAPHIC STUDY UNDER INTERMITTENT PHOTIC STIMULATION].
    Annales medicales de Nancy, 1963, Volume: 2

    Topics: Acetazolamide; Adolescent; Alcoholism; Anticonvulsants; Anxiety; Bemegride; Dichlorphenamide; Electr

1963
THE INFANT WITH EPILEPSY.
    Southwestern medicine, 1963, Volume: 44

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Birth Injuries; Classific

1963
MECHANISM OF ANTICONVULSANT ACTION OF KETOGENIC DIET. STUDIES IN ANIMALS WITH EXPERIMENTAL SEIZURES AND IN CHILDREN WITH PETIT MAL EPILEPSY.
    American journal of diseases of children (1960), 1964, Volume: 107

    Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Adolescent; Anticonvulsants; Barbiturates; Biomedica

1964
FEBRILE CONVULSIONS. THE EFFECTS OF SPINAL CORD TRANSECTION AND ACETAZOLAMIDE.
    Neurology, 1964, Volume: 14

    Topics: Acetazolamide; Cerebral Cortex; Fever; Pharmacology; Physiology; Rats; Research; Seizures; Seizures,

1964
[DIAGNOSIS AND THERAPY OF CONVULSIVE DISEASES IN CHILDHOOD].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Amino Acids; Barbiturates; Brain Diseases; C

1964
EPILEPSY IN CHILDHOOD: CLASSIFICATION AND TREATMENT.
    Postgraduate medical journal, 1964, Volume: 40

    Topics: Acetazolamide; Adrenal Cortex Hormones; Angiomatosis; Barbiturates; Child; Classification; Electroen

1964
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
    Epilepsia, 1964, Volume: 5

    Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepox

1964
ELECTROCONVULSIVE RESPONSES OF RATS TO CONVULSANT AND ANTICONVULSANT DRUGS DURING ACCLIMATIZATION AT HIGH ALTITUDE (12,470 FEET, 3,800 M).
    Proceedings of the Western Pharmacology Society, 1964, Volume: 7

    Topics: Acclimatization; Acetazolamide; Altitude; Anticonvulsants; Convulsants; Electric Stimulation; Neurop

1964
BEHAVIOR DISORDERS OF CHILDREN WITH CEREBRAL DYSRHYTHMIAS; SUCCESSFUL TREATMENT OF SUBCONVULSIVE DYSRHYTHMIA WITH ANTICONVULSANTS.
    Archives of general psychiatry, 1964, Volume: 11

    Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Child; Child Behavior Disorders; Conduct

1964
ELECTROCONVULSIVE RESPONSES OF RATS TO CONVULSANT AND ANTICONVULSANT DRUGS DURING HIGH-ALTITUDE ACCLIMATIZATION.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 146

    Topics: Acclimatization; Acetazolamide; Altitude; Anticonvulsants; Convulsants; Electricity; Electroshock; P

1964
CHILD CARE IN GENERAL PRACTICE. CONVULSIONS IN INFANCY AND CHILDHOOD. II.
    British medical journal, 1965, Feb-20, Volume: 1, Issue:5433

    Topics: Acetazolamide; Anticonvulsants; Bromides; Child; Child Care; Chloral Hydrate; Diagnosis; Drug Therap

1965
[THE REPRODUCTION OF AUDIOGENIC CONVULSIONS AFTER THE PRELIMINARY ADMINISTRATION OF PYRAMIDONE TO ANIMALS].
    Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 57

    Topics: Acetazolamide; Aminopyrine; Anticonvulsants; Antipyrine; Epilepsy, Reflex; Mice; Pharmacology; Pheno

1964
[DRUG THERAPY OF EPILEPSY. INTRODUCTION].
    Nordisk medicin, 1965, Mar-11, Volume: 73

    Topics: Acetazolamide; Barbiturates; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epi

1965
[Effect of acetazolamide on the latency of hyperbaric oxygen-induced convulsion].
    Sheng li xue bao : [Acta physiologica Sinica], 2004, Apr-25, Volume: 56, Issue:2

    Topics: Acetazolamide; Animals; Brain; Hyperbaric Oxygenation; Male; Oxidative Stress; Oxygen; Random Alloca

2004
[Nitric oxide and carbon dioxide in neurotoxicity induced by oxygen under pressure].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2004, Volume: 90, Issue:4

    Topics: Acetazolamide; Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation;

2004
Mechanisms of action of antiepileptic drugs.
    Clinical neuropharmacology, 1982, Volume: 5, Issue:1

    Topics: Acetazolamide; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Carbama

1982
Effects of some antiepileptic drugs in pentetrazol-induced convulsions in mice lesioned with kainic acid.
    Epilepsia, 1981, Volume: 22, Issue:4

    Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Dose-Response Relationship, Drug;

1981
Acetazolamide and CO2 in hyperbaric oxygen toxicity.
    Undersea biomedical research, 1982, Volume: 9, Issue:1

    Topics: Acetazolamide; Animals; Barotrauma; Carbon Dioxide; Hyperbaric Oxygenation; Male; Oxygen; Rats; Rats

1982
[Methods of reduction therapy for patients with congenital hydrocephalus after conservative and surgical methods of treatment].
    Pediatriia, 1983, Issue:4

    Topics: Acetazolamide; Child, Preschool; Humans; Hydrocephalus; Infant; Intracranial Pressure; Seizures

1983
Flash-evoked afterdischarge in rat as a model of the absence seizure: dose-response studies with therapeutic drugs.
    Epilepsia, 1980, Volume: 21, Issue:5

    Topics: Acetazolamide; Animals; Dose-Response Relationship, Drug; Ethosuximide; Evoked Potentials; Male; Mep

1980
Pharmacological inhibition of brain carbonic anhydrase protects against 4-aminopyridine seizures.
    Acta physiologica Hungarica, 1994, Volume: 82, Issue:2

    Topics: 4-Aminopyridine; Acetazolamide; Animals; Brain; Brain Chemistry; Carbonic Anhydrase Inhibitors; Carb

1994
Anticonvulsant properties of copper acetazolamide complexes.
    Journal of inorganic biochemistry, 1994, Aug-01, Volume: 55, Issue:2

    Topics: Acetazolamide; Animals; Anticonvulsants; Copper; Electroshock; Male; Mice; Organometallic Compounds;

1994
A comparison of topiramate and acetazolamide on seizure duration and paired-pulse inhibition in the dentate gyrus of the rat.
    Epilepsy research, 2000, Volume: 40, Issue:2-3

    Topics: Acetazolamide; Animals; Anticonvulsants; Dentate Gyrus; Drug Evaluation, Preclinical; Fructose; Long

2000
Changes in seizure susceptibility after intracerebral treatment with 5,7-dihydroxytryptamine: role of serotonergic neurons.
    Annals of the New York Academy of Sciences, 1978, Jun-12, Volume: 305

    Topics: 5,7-Dihydroxytryptamine; Acetazolamide; Animals; Anticonvulsants; Dihydroxytryptamines; Electroshock

1978
Effect of anticonvulsants on cortical focal seizure in cats.
    Epilepsia, 1977, Volume: 18, Issue:1

    Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Epileps

1977
Pharmacological prophylaxis against the development of kindled amygdaloid seizures.
    Annals of neurology, 1977, Volume: 2, Issue:3

    Topics: Acetazolamide; Amygdala; Animals; Cats; Dexamethasone; Electric Stimulation; Ethosuximide; Phenobarb

1977
Use of acetazolamide-challenge xenon CT in the assessment of cerebral blood flow dynamics in patients with arteriovenous malformations.
    AJNR. American journal of neuroradiology, 1990, Volume: 11, Issue:3

    Topics: Acetazolamide; Adolescent; Adult; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Female; H

1990
Drug treatment of convulsive disorders.
    The New England journal of medicine, 1972, Mar-02, Volume: 286, Issue:9

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; E

1972
[Anticonvulsants. 7. Treatment of myclonic-astatic epilepsy in small children].
    Lakartidningen, 1971, Oct-18, Volume: 68

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Child, Preschool; Diazepam; Epilepsy, Absence; Epilepsy,

1971
Classification and treatment of seizure disorders in children.
    Virginia medical monthly, 1970, Volume: 97, Issue:2

    Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child,

1970
Potentiation of the anticonvulsant action of acetazolamide.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:12

    Topics: Acetazolamide; Amphetamine; Animals; Anticonvulsants; Caffeine; Cocaine; Desipramine; Drug Synergism

1966
[Comparative action of p-chlorbenzolsulfonamide with other anticonvulsants in audiogenic convulsions in rats].
    Acta biologica et medica Germanica, 1969, Volume: 23, Issue:4

    Topics: Acetazolamide; Animals; Anticonvulsants; Hearing; Noise; Phenobarbital; Primidone; Rats; Seizures; S

1969
Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.
    Drugs, 1972, Volume: 4, Issue:3

    Topics: Acetates; Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Dibenzazepines; Electroencephalog

1972
A complicated case of convulsions.
    Clinical pediatrics, 1973, Volume: 12, Issue:3

    Topics: Acetazolamide; Barbiturates; Bone and Bones; Child, Preschool; Female; Humans; Hypocalcemia; Radiogr

1973
Expanding skull fracture of childhood.
    British medical journal, 1973, Nov-10, Volume: 4, Issue:5888

    Topics: Acetazolamide; Hemianopsia; Hemiplegia; Humans; Infant; Male; Phenytoin; Radiography; Seizures; Skul

1973
[Effects of carbonic anhydrase inhibition on oxygen poisoning of the central nervous system (author's transl)].
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1974, Jun-24, Volume: 163, Issue:2

    Topics: Acetazolamide; Animals; Blood Flow Velocity; Blood Gas Analysis; Carbon Dioxide; Carbonic Anhydrase

1974
[New methods of seizure treatment in epilepsy].
    Munchener medizinische Wochenschrift (1950), 1965, Nov-05, Volume: 107, Issue:45

    Topics: Acetazolamide; Anticonvulsants; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tempo

1965
The hyperexcitable neuron as a model for the laboratory analysis of anticonvulsant drugs.
    Epilepsia, 1969, Volume: 10, Issue:2

    Topics: Acetazolamide; Action Potentials; Aluminum; Animals; Behavior, Animal; Cats; Cerebral Cortex; Electr

1969
Studies on the functional significance of carbonic anhydrase in central nervous system.
    Brain research, 1971, Aug-07, Volume: 31, Issue:1

    Topics: Acetazolamide; Animals; Anticonvulsants; Brain; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases;

1971
Reserpine and acetazolamide in maximum electroshock seizure in the rat.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:3

    Topics: Acetazolamide; Animals; Drug Antagonism; Electroshock; Male; Rats; Receptors, Drug; Reserpine; Seizu

1971
High frequency electro-shock seizures and their antagonism during postnatal development in the mouse. II. Effects of phenobarbital sodium, mephobarbital, trimethadione, dimethadione, ethosuximide and acetazolamide.
    Acta pharmacologica et toxicologica, 1969, Volume: 27, Issue:4

    Topics: Acetazolamide; Age Factors; Animals; Animals, Newborn; Anticonvulsants; Electroshock; Ethosuximide;

1969
Anticonvulsant drugs and self-stimulation rates in rats.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 185, Issue:2

    Topics: Acetazolamide; Animals; Chlordiazepoxide; Electrodes; Male; Meprobamate; Pentobarbital; Pentylenetet

1970
[Relationship between convulsions induced by toxic substances and anticonvulsants].
    Igaku to seibutsugaku. Medicine and biology, 1967, Oct-10, Volume: 75, Issue:4

    Topics: Acetazolamide; Anilides; Animals; Anticonvulsants; Female; Methacholine Compounds; Mice; Pentylenete

1967
Studies on electrically induced-seizures and their antagonism by anticonvulsants during neonatal development in the mouse.
    Acta pharmacologica et toxicologica, 1967, Volume: 25

    Topics: Acetazolamide; Animals; Animals, Newborn; Anticonvulsants; Electric Stimulation; Ethosuximide; Mice;

1967
The anticonvulsant potency of inhibitors of carbonic anhydrase in young and adult rats and mice.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 161, Issue:2

    Topics: Acetazolamide; Age Factors; Animals; Anticonvulsants; Azoles; Brain; Carbon Dioxide; Carbonic Anhydr

1968
Antiepileptic property of inhibitors of carbonic anhydrase.
    Biochemical pharmacology, 1965, Volume: 14, Issue:6

    Topics: Acetazolamide; Animals; Anticonvulsants; Brain; Carbonic Anhydrase Inhibitors; Electroconvulsive The

1965
The mechanism of action of anticonvulsants. II. Acetazolamide.
    Life sciences, 1966, Volume: 5, Issue:8

    Topics: Acetazolamide; Animals; Dextroamphetamine; Dihydroxyphenylalanine; Electric Stimulation; Electroshoc

1966