acetaminophen has been researched along with Urogenital Prolapse in 3 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Excerpt | Relevance | Reference |
---|---|---|
"To compare the effect of preoperative intravenous (IV) acetaminophen compared with placebo on pain scores after pelvic organ prolapse surgery." | 9.30 | Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial. ( Shepherd, JP; Turner, LC; Zyczynski, HM, 2019) |
"To compare the effect of preoperative intravenous (IV) acetaminophen compared with placebo on pain scores after pelvic organ prolapse surgery." | 5.30 | Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial. ( Shepherd, JP; Turner, LC; Zyczynski, HM, 2019) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 2 (66.67) | 2.80 |
Authors | Studies |
---|---|
Gabriel, I | 1 |
Abdalian, T | 1 |
Minassian, VA | 1 |
Ramaseshan, AS | 1 |
O'Sullivan, DM | 1 |
Steinberg, AC | 1 |
Tunitsky-Bitton, E | 1 |
Turner, LC | 1 |
Zyczynski, HM | 1 |
Shepherd, JP | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
The Impact of IV Acetaminophen on Postoperative Pain in Women Undergoing Pelvic Organ Prolapse Repair: A Double-Blind Randomized Placebo Controlled Trial[NCT02155738] | Phase 4 | 204 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
The Impact of Tamsulosin on Duration of Post-Operative Urinary Retention in Women Undergoing Pelvic Reconstructive Surgery- A Double Blind, Randomized, Placebo-Controlled Study[NCT04597372] | Phase 2 | 154 participants (Anticipated) | Interventional | 2021-11-03 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"VAS or Visual Analog Score is a quantitative measure, in this study, of pain that the subject is currently experiencing. The VAS is presented as a straight line which measures 100mm. The subject is instructed to mark an 'X' through this line reflecting the amount of pain that they are currently experiencing. Zero would indicate no pain, while '100' would indicate the most severe pain ever. Thus the total range for this scale would be 0-100 mm. Higher values indicate more pain; lower value indicate less pain.~For this outcome measure, the VAS scores from Baseline and the VAS scores from 24 hours after the end of surgery are being used. The change from baseline in postoperative pain equals the 24 hour VAS score minus the baseline VAS score.~The Change from Baseline would be the 24-hour VAS score minus the Baseline VAS score. Higher values indicate more pain; lower values indicate less pain." (NCT02155738)
Timeframe: 24 hours
Intervention | units on a scale (Mean) |
---|---|
Vaginal Surgery - Placebo | 20.5 |
Vaginal Surgery - IV Acetaminophen | 29.2 |
Laparoscopic Surgery - Placebo | 20.7 |
Laparoscopic Surgery - IV Acetaminophen | 20.1 |
Equianalgesic dosage tables will be used to convert intra- and postoperative narcotics into morphine equivalents to compare narcotic requirements for the first week after surgery. Higher numbers indicate higher narcotic usage. (NCT02155738)
Timeframe: First 24 hours
Intervention | mg (Mean) |
---|---|
Vaginal Surgery - Placebo | 32.5 |
Vaginal Surgery - IV Acetaminophen | 31.6 |
Laparoscopic Surgery - Placebo | 47.4 |
Laparoscopic Surgery - IV Acetaminophen | 44.5 |
"Interference of pain with physical, mental and social activities will be measured by the Patient Reported Outcomes Measures Information Systems-Pain Interference-Short Form 8a (PROMIS PI-SF-8a) administered on POD#7.~This instrument measures the self reported consequences of pain on relevant aspects of one's life. This scale is considered to be universal rather than disease specific. Each question has five response options ranging in value from 1-5. The total raw score for the scale is the sum of all values. The total raw score can range from 8-40. All questions much be answered to obtain a valid score.~A higher PROMIS score indicates more 'hurt' or pain." (NCT02155738)
Timeframe: 1 week
Intervention | units on a scale (Mean) |
---|---|
Vaginal Surgery - Placebo | 18.4 |
Vaginal Surgery - IV Acetaminophen | 22.0 |
Laparoscopic Surgery - Placebo | 22.9 |
Laparoscopic Surgery - IV Acetaminophen | 25.2 |
1 trial available for acetaminophen and Urogenital Prolapse
Article | Year |
---|---|
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg | 2019 |
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg | 2019 |
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg | 2019 |
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg | 2019 |
2 other studies available for acetaminophen and Urogenital Prolapse
Article | Year |
---|---|
Perioperative use of pain medications in vaginal versus laparoscopic pelvic organ prolapse surgery.
Topics: Acetaminophen; Analgesics, Opioid; Female; Humans; Laparoscopy; Pain, Postoperative; Pelvic Organ Pr | 2022 |
A comprehensive model for pain management in patients undergoing pelvic reconstructive surgery: a prospective clinical practice study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2020 |