Page last updated: 2024-10-22

acetaminophen and Urinary Retention

acetaminophen has been researched along with Urinary Retention in 7 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Urinary Retention: Inability to empty the URINARY BLADDER with voiding (URINATION).

Research Excerpts

ExcerptRelevanceReference
"To compare the effect of preoperative intravenous (IV) acetaminophen compared with placebo on pain scores after pelvic organ prolapse surgery."9.30Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial. ( Shepherd, JP; Turner, LC; Zyczynski, HM, 2019)
"To compare the effect of preoperative intravenous (IV) acetaminophen compared with placebo on pain scores after pelvic organ prolapse surgery."5.30Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial. ( Shepherd, JP; Turner, LC; Zyczynski, HM, 2019)
"Postoperative pain was assessed by means of a modified Objective Pain Score and analgesia was administered if this score exceeded four."2.69The effect of ketamine on 0.25% and 0.125% bupivacaine for caudal epidural blockade in children. ( Aldridge, LM; Doyle, E; Findlow, D; Johnston, P, 1999)
"Midazolam was used in 95 patients (56%), with an average dose of 35 (±14) μg/kg/h."1.51Postsurgery analgesic and sedative drug use in a French neonatal intensive care unit: A single-center retrospective cohort study. ( Benahmed-Canat, A; Canat, G; Claris, O; Kassai, B; Nguyen, KA; Paret, N; Plaisant, F; Rabilloud, M; Riche, B, 2019)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Wang, TH1
Kiu, KT1
Yen, MH1
Chang, TC1
Turner, LC1
Zyczynski, HM1
Shepherd, JP1
Benahmed-Canat, A1
Plaisant, F1
Riche, B1
Rabilloud, M1
Canat, G1
Paret, N1
Claris, O1
Kassai, B1
Nguyen, KA1
Linder, CM1
Hey, M1
Wilson, I1
Johnson, MI1
Pavy, E1
Compère, V1
Fourdrinier, V1
Beghin, CE1
Dujardin, F1
Dureuil, B1
Johnston, P1
Findlow, D1
Aldridge, LM1
Doyle, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Impact of IV Acetaminophen on Postoperative Pain in Women Undergoing Pelvic Organ Prolapse Repair: A Double-Blind Randomized Placebo Controlled Trial[NCT02155738]Phase 4204 participants (Actual)Interventional2014-07-31Completed
The Impact of Tamsulosin on Duration of Post-Operative Urinary Retention in Women Undergoing Pelvic Reconstructive Surgery- A Double Blind, Randomized, Placebo-Controlled Study[NCT04597372]Phase 2154 participants (Anticipated)Interventional2021-11-03Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Postoperative Pain

"VAS or Visual Analog Score is a quantitative measure, in this study, of pain that the subject is currently experiencing. The VAS is presented as a straight line which measures 100mm. The subject is instructed to mark an 'X' through this line reflecting the amount of pain that they are currently experiencing. Zero would indicate no pain, while '100' would indicate the most severe pain ever. Thus the total range for this scale would be 0-100 mm. Higher values indicate more pain; lower value indicate less pain.~For this outcome measure, the VAS scores from Baseline and the VAS scores from 24 hours after the end of surgery are being used. The change from baseline in postoperative pain equals the 24 hour VAS score minus the baseline VAS score.~The Change from Baseline would be the 24-hour VAS score minus the Baseline VAS score. Higher values indicate more pain; lower values indicate less pain." (NCT02155738)
Timeframe: 24 hours

Interventionunits on a scale (Mean)
Vaginal Surgery - Placebo20.5
Vaginal Surgery - IV Acetaminophen29.2
Laparoscopic Surgery - Placebo20.7
Laparoscopic Surgery - IV Acetaminophen20.1

Cumulative Narcotic Consumption Over the First 24 Hours

Equianalgesic dosage tables will be used to convert intra- and postoperative narcotics into morphine equivalents to compare narcotic requirements for the first week after surgery. Higher numbers indicate higher narcotic usage. (NCT02155738)
Timeframe: First 24 hours

Interventionmg (Mean)
Vaginal Surgery - Placebo32.5
Vaginal Surgery - IV Acetaminophen31.6
Laparoscopic Surgery - Placebo47.4
Laparoscopic Surgery - IV Acetaminophen44.5

Interference of Pain With Physical, Mental and Social Activities

"Interference of pain with physical, mental and social activities will be measured by the Patient Reported Outcomes Measures Information Systems-Pain Interference-Short Form 8a (PROMIS PI-SF-8a) administered on POD#7.~This instrument measures the self reported consequences of pain on relevant aspects of one's life. This scale is considered to be universal rather than disease specific. Each question has five response options ranging in value from 1-5. The total raw score for the scale is the sum of all values. The total raw score can range from 8-40. All questions much be answered to obtain a valid score.~A higher PROMIS score indicates more 'hurt' or pain." (NCT02155738)
Timeframe: 1 week

Interventionunits on a scale (Mean)
Vaginal Surgery - Placebo18.4
Vaginal Surgery - IV Acetaminophen22.0
Laparoscopic Surgery - Placebo22.9
Laparoscopic Surgery - IV Acetaminophen25.2

Trials

3 trials available for acetaminophen and Urinary Retention

ArticleYear
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2019, Volume: 133, Issue:3

    Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg

2019
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2019, Volume: 133, Issue:3

    Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg

2019
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2019, Volume: 133, Issue:3

    Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg

2019
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2019, Volume: 133, Issue:3

    Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg

2019
[Evaluation of postoperative analgesia with continuous iliofascial nerve sheath block after total hip arthroplasty replacement: a pilot study].
    Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:2

    Topics: Acetaminophen; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narco

2007
The effect of ketamine on 0.25% and 0.125% bupivacaine for caudal epidural blockade in children.
    Paediatric anaesthesia, 1999, Volume: 9, Issue:1

    Topics: Acetaminophen; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Anesthesia Recovery Period

1999

Other Studies

4 other studies available for acetaminophen and Urinary Retention

ArticleYear
Comparison of the short-term outcomes of using DST and PPH staplers in the treatment of grade III and IV hemorrhoids.
    Scientific reports, 2020, 03-23, Volume: 10, Issue:1

    Topics: Acetaminophen; Anal Canal; Analgesics; Anus Diseases; Constriction, Pathologic; Equipment Design; Fe

2020
Postsurgery analgesic and sedative drug use in a French neonatal intensive care unit: A single-center retrospective cohort study.
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2019, Volume: 26, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cohort Studies; Drug Utilization; Femal

2019
A 3-year-old trauma patient with progressive paralysis.
    Journal of emergency nursing, 2010, Volume: 36, Issue:6

    Topics: Accidents, Traffic; Acetaminophen; Analgesics, Non-Narcotic; Catheters, Indwelling; Child, Preschool

2010
Stellate ganglion blockade (SGB) for refractory index finger pain - a case report.
    Annals of physical and rehabilitation medicine, 2011, Volume: 54, Issue:3

    Topics: Abdominal Pain; Accidental Falls; Acetaminophen; Adult; Amines; Autonomic Nerve Block; Chronic Disea

2011