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acetaminophen and Tyrosinemias

acetaminophen has been researched along with Tyrosinemias in 1 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Tyrosinemias: A group of disorders which have in common elevations of tyrosine in the blood and urine secondary to an enzyme deficiency. Type I tyrosinemia features episodic weakness, self-mutilation, hepatic necrosis, renal tubular injury, and seizures and is caused by a deficiency of the enzyme fumarylacetoacetase. Type II tyrosinemia features INTELLECTUAL DISABILITY, painful corneal ulcers, and keratoses of the palms and plantar surfaces and is caused by a deficiency of the enzyme TYROSINE TRANSAMINASE. Type III tyrosinemia features INTELLECTUAL DISABILITY and is caused by a deficiency of the enzyme 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE. (Menkes, Textbook of Child Neurology, 5th ed, pp42-3)

Research Excerpts

ExcerptRelevanceReference
" Similarly, Fah(-/-) animals with liver injury were also resistant to apoptosis induced by the Fas ligand Jo-2 and to necrosis-like cell death induced by acetaminophen (APAP)."3.72Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death. ( Al-Dhalimy, M; Finegold, M; Grompe, M; Groopman, J; Iordanov, MS; Ou, CN; Ryabinina, O; van Den Berg, IE; Vogel, A, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vogel, A1
van Den Berg, IE1
Al-Dhalimy, M1
Groopman, J1
Ou, CN1
Ryabinina, O1
Iordanov, MS1
Finegold, M1
Grompe, M1

Other Studies

1 other study available for acetaminophen and Tyrosinemias

ArticleYear
Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death.
    Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Cell Survival; Central Nervous System D

2004