Page last updated: 2024-10-22

acetaminophen and Transfusion Reaction

acetaminophen has been researched along with Transfusion Reaction in 9 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Transfusion Reaction: Complications of BLOOD TRANSFUSION. Included adverse reactions are common allergic and febrile reactions; hemolytic (delayed and acute) reactions; and other non-hemolytic adverse reactions such as infections and adverse immune reactions related to immunocompatibility.

Research Excerpts

ExcerptRelevanceReference
"Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions."9.13A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions. ( Case, LD; Cruz, JM; Hurd, DD; Kennedy, LD; Pomper, GJ, 2008)
"Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions."5.13A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions. ( Case, LD; Cruz, JM; Hurd, DD; Kennedy, LD; Pomper, GJ, 2008)
"Routine premedication with acetaminophen and antihistamines did not prevent nonhemolytic transfusion reactions; however, the estimate of effect was greatest for febrile reactions."5.01Premedication for the prevention of nonhemolytic transfusion reactions: a systematic review and meta-analysis. ( Arnold, DM; Morin, PA; Ning, S; Solh, Z, 2019)
"Chronic hepatitis C was a frequent complication in patients treated for malignancy until the introduction of anti-HCV screening tests for blood donors."2.69Interferon treatment of chronic hepatitis C in patients cured of pediatric malignancies. ( Bortolotti, F; Brugiolo, A; Cesaro, S; Cusinato, R; Guido, M; Masiero, L; Petris, MG; Rossetti, F; Zanesco, L, 2000)
"Sepsis is a heterogeneous clinical syndrome that is complicated commonly by acute kidney injury (sepsis-AKI)."2.66The Role of Circulating Cell-Free Hemoglobin in Sepsis-Associated Acute Kidney Injury. ( Kerchberger, VE; Ware, LB, 2020)
"Febrile nonhemolytic transfusion reactions (FNHTRs) cause unwelcome interruptions during the course of blood product transfusions and necessitate measures to verify the nature of the reaction and to exclude certain dangerous reactions, such as hemolytic and septic phenomena."1.32Febrile nonhemolytic transfusion reactions. Management by premedication and cost implications in adult patients. ( Ezidiegwu, CN; Henry, JB; Kelly, KC; Lauenstein, KJ; Rosales, LG, 2004)
"Acetaminophen levels were determined in 1,176 sera separated from donated blood."1.26Incidence of acetaminophen in donated blood. ( Kidroni, G; Menczel, J; Sharon, R, 1982)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Ning, S1
Solh, Z1
Arnold, DM1
Morin, PA1
Kerchberger, VE1
Ware, LB1
Duran, J1
Siddique, S1
Cleary, M1
Kennedy, LD1
Case, LD1
Hurd, DD1
Cruz, JM1
Pomper, GJ1
Tobian, AA1
King, KE1
Ness, PM1
Martí-Carvajal, AJ1
Solà, I1
González, LE1
Leon de Gonzalez, G1
Rodriguez-Malagon, N1
Ezidiegwu, CN1
Lauenstein, KJ1
Rosales, LG1
Kelly, KC1
Henry, JB1
Sharon, R1
Menczel, J1
Kidroni, G1
Cesaro, S1
Bortolotti, F1
Petris, MG1
Brugiolo, A1
Cusinato, R1
Guido, M1
Rossetti, F1
Masiero, L1
Zanesco, L1

Reviews

4 reviews available for acetaminophen and Transfusion Reaction

ArticleYear
Premedication for the prevention of nonhemolytic transfusion reactions: a systematic review and meta-analysis.
    Transfusion, 2019, Volume: 59, Issue:12

    Topics: Acetaminophen; Blood Transfusion; Histamine Antagonists; Humans; Premedication; Randomized Controlle

2019
The Role of Circulating Cell-Free Hemoglobin in Sepsis-Associated Acute Kidney Injury.
    Seminars in nephrology, 2020, Volume: 40, Issue:2

    Topics: Acetaminophen; Acute Kidney Injury; Anemia, Sickle Cell; Animals; Coronary Artery Bypass; Disseminat

2020
Effects of Leukoreduction and Premedication With Acetaminophen and Diphenhydramine in Minimizing Febrile Nonhemolytic Transfusion Reactions and Allergic Transfusion Reactions During and After Blood Product Administration: A Literature Review With Recommen
    Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses, 2014, Volume: 31, Issue:4

    Topics: Acetaminophen; Diphenhydramine; Drug Administration Schedule; Erythrocyte Transfusion; Evidence-Base

2014
Pharmacological interventions for the prevention of allergic and febrile non-haemolytic transfusion reactions.
    The Cochrane database of systematic reviews, 2010, Jun-16, Issue:6

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Fever; Histamine H1 Antagon

2010

Trials

2 trials available for acetaminophen and Transfusion Reaction

ArticleYear
A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions.
    Transfusion, 2008, Volume: 48, Issue:11

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Do

2008
Interferon treatment of chronic hepatitis C in patients cured of pediatric malignancies.
    Haematologica, 2000, Volume: 85, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Alanine Transaminase; Alopecia; Asthenia; Chlorpheniramine; DNA, V

2000

Other Studies

3 other studies available for acetaminophen and Transfusion Reaction

ArticleYear
Prevention of febrile nonhemolytic and allergic transfusion reactions with pretransfusion medication: is this evidence-based medicine?
    Transfusion, 2008, Volume: 48, Issue:11

    Topics: Acetaminophen; Anemia, Hemolytic; Diphenhydramine; Evidence-Based Medicine; Fever; Humans; Leukocyte

2008
Febrile nonhemolytic transfusion reactions. Management by premedication and cost implications in adult patients.
    Archives of pathology & laboratory medicine, 2004, Volume: 128, Issue:9

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Blood Transfusion; Costs and Cost Analysis; Fever; H

2004
Incidence of acetaminophen in donated blood.
    Vox sanguinis, 1982, Volume: 43, Issue:3

    Topics: Acetaminophen; Blood Donors; Chromatography, High Pressure Liquid; Colorimetry; Drug Hypersensitivit

1982