acetaminophen has been researched along with Toothache in 38 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Toothache: Pain in the adjacent areas of the teeth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this prospective randomized, double-blind, placebo-controlled study was to determine the effects of a combination dose of 1000 mg acetaminophen/10 mg hydrocodone on cold pulpal testing in patients experiencing symptomatic irreversible pulpitis." | 9.19 | Does acetaminophen/hydrocodone affect cold pulpal testing in patients with symptomatic irreversible pulpitis? A prospective, randomized, double-blind, placebo-controlled study. ( Drum, M; Fowler, S; Fullmer, S; Reader, A, 2014) |
| "The efficacy of oral fentiazac (100 mg QID) was compared with that of paracetamol (500 mg QID) in a single-blind trial in 30 patients suffering from post-endodontic periodontitis secondary to infiltrative or abscessed pulpitis." | 9.05 | Single-blind clinical trial comparing use of fentiazac and paracetamol in postendodontic periodontitis. ( Leguen, MA, 1985) |
| "The effectiveness of nonprescription analgesics--acetaminophen and aspirin--in providing subjective relief of preoperative dental pain was evaluated in a varied population of adults." | 7.66 | Evaluation of acetaminophen and aspirin in the relief of preoperative dental pain. ( Kilkuts, A; Korberly, BH; Orkand, RK; Schreiber, GF; Segal, H, 1980) |
| "Nonopioid medications, specifically nonsteroidal anti-inflammatory drugs like ibuprofen and naproxen alone or in combination with acetaminophen, are recommended for managing acute dental pain after 1 or more tooth extractions (that is, simple and surgical) and the temporary management of toothache in children (conditional recommendation, very low certainty)." | 5.41 | Evidence-based clinical practice guideline for the pharmacologic management of acute dental pain in children: A report from the American Dental Association Science and Research Institute, the University of Pittsburgh School of Dental Medicine, and the Cen ( Aghaloo, T; Carrasco-Labra, A; Claytor, JW; Dawson, T; Dhar, V; Dionne, RA; Espinoza, L; Gordon, SM; Hersh, EV; Law, AS; Li, BS; Miroshnychenko, A; Moore, PA; Pahlke, S; Pilcher, L; Polk, DE; Schwartz, PJ; Shirey, M; Suda, KJ; Tampi, M; Turturro, MA; Urquhart, O; Wright, ML, 2023) |
| "The purpose of this prospective randomized, double-blind, placebo-controlled study was to determine the effects of a combination dose of 1000 mg acetaminophen/10 mg hydrocodone on cold pulpal testing in patients experiencing symptomatic irreversible pulpitis." | 5.19 | Does acetaminophen/hydrocodone affect cold pulpal testing in patients with symptomatic irreversible pulpitis? A prospective, randomized, double-blind, placebo-controlled study. ( Drum, M; Fowler, S; Fullmer, S; Reader, A, 2014) |
| "The purpose of this prospective, double-blind, randomized study was to evaluate pain reduction using an intraosseous injection of slow-releasing methylprednisolone in teeth with irreversible pulpitis." | 5.09 | Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol. ( Beck, M; Gallatin, E; Nist, R; Reader, A, 2000) |
| "The efficacy of oral fentiazac (100 mg QID) was compared with that of paracetamol (500 mg QID) in a single-blind trial in 30 patients suffering from post-endodontic periodontitis secondary to infiltrative or abscessed pulpitis." | 5.05 | Single-blind clinical trial comparing use of fentiazac and paracetamol in postendodontic periodontitis. ( Leguen, MA, 1985) |
| "The effectiveness of nonprescription analgesics--acetaminophen and aspirin--in providing subjective relief of preoperative dental pain was evaluated in a varied population of adults." | 3.66 | Evaluation of acetaminophen and aspirin in the relief of preoperative dental pain. ( Kilkuts, A; Korberly, BH; Orkand, RK; Schreiber, GF; Segal, H, 1980) |
| "Tramadol/APAP was superior to tramadol (P < 0." | 2.71 | A double-blind placebo-controlled comparison of tramadol/acetaminophen and tramadol in patients with postoperative dental pain. ( Fisher, A; Fricke, JR; Hewitt, DJ; Jordan, DM; Rosenthal, NR, 2004) |
| " To formulate regimens properly, it is essential to appreciate basic pharmacological principles and appropriate dosage strategies for each of the available analgesic classes." | 2.46 | Pain management: Part 1: Managing acute and postoperative dental pain. ( Becker, DE, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (18.42) | 18.7374 |
| 1990's | 6 (15.79) | 18.2507 |
| 2000's | 10 (26.32) | 29.6817 |
| 2010's | 14 (36.84) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Carrasco-Labra, A | 1 |
| Polk, DE | 1 |
| Urquhart, O | 1 |
| Aghaloo, T | 1 |
| Claytor, JW | 1 |
| Dhar, V | 1 |
| Dionne, RA | 1 |
| Espinoza, L | 1 |
| Gordon, SM | 1 |
| Hersh, EV | 1 |
| Law, AS | 1 |
| Li, BS | 1 |
| Schwartz, PJ | 1 |
| Suda, KJ | 1 |
| Turturro, MA | 1 |
| Wright, ML | 1 |
| Dawson, T | 1 |
| Miroshnychenko, A | 1 |
| Pahlke, S | 1 |
| Pilcher, L | 1 |
| Shirey, M | 1 |
| Tampi, M | 1 |
| Moore, PA | 1 |
| Leader, R | 1 |
| Hackett, J | 1 |
| Al-Naher, A | 1 |
| O'Sullivan, LM | 1 |
| Ahmed, N | 1 |
| Sidebottom, AJ | 1 |
| Hancocks, S | 1 |
| Horisk, N | 1 |
| Fedorowicz, Z | 2 |
| van Zuuren, EJ | 2 |
| Farman, AG | 2 |
| Agnihotry, A | 2 |
| Al-Langawi, JH | 2 |
| Skoglund, LA | 1 |
| Vigen, EC | 1 |
| Fowler, S | 1 |
| Fullmer, S | 1 |
| Drum, M | 1 |
| Reader, A | 2 |
| Rice, S | 1 |
| Siddique, I | 1 |
| Mahmood, H | 1 |
| Mohammed-Ali, R | 1 |
| Voelker, M | 1 |
| Schachtel, BP | 1 |
| Cooper, SA | 1 |
| Gatoulis, SC | 1 |
| Becker, DE | 1 |
| Vogel, J | 1 |
| Heard, KJ | 1 |
| Carlson, C | 1 |
| Lange, C | 1 |
| Mitchell, G | 1 |
| Kardelis, AC | 1 |
| Meinberg, TA | 1 |
| Sulte, HR | 1 |
| Gound, TG | 1 |
| Marx, DB | 1 |
| Reinhardt, RA | 1 |
| Dodd, MD | 2 |
| Graham, CA | 1 |
| Haas, DA | 1 |
| Locher, C | 1 |
| Lambare, B | 1 |
| Fischer, D | 1 |
| Labayle, D | 1 |
| Fricke, JR | 1 |
| Hewitt, DJ | 1 |
| Jordan, DM | 1 |
| Fisher, A | 1 |
| Rosenthal, NR | 1 |
| Thomas, MB | 1 |
| Moran, N | 1 |
| Smart, K | 1 |
| Crean, S | 1 |
| Seymour, RA | 1 |
| Korberly, BH | 1 |
| Schreiber, GF | 1 |
| Kilkuts, A | 1 |
| Orkand, RK | 1 |
| Segal, H | 1 |
| Preshaw, PM | 1 |
| Meechan, JG | 1 |
| Torabinejad, M | 1 |
| Cymerman, JJ | 1 |
| Frankson, M | 1 |
| Lemon, RR | 1 |
| Maggio, JD | 1 |
| Schilder, H | 1 |
| Hern, S | 1 |
| Harman, K | 1 |
| Clement, M | 1 |
| Black, MM | 1 |
| Sadeghein, A | 1 |
| Shahidi, N | 1 |
| Dehpour, AR | 1 |
| Carnes, PL | 1 |
| Cook, B | 1 |
| Eleazer, PD | 1 |
| Scheetz, JP | 1 |
| Gallatin, E | 1 |
| Nist, R | 1 |
| Beck, M | 1 |
| Egemonye, V | 1 |
| Bloomquist, DS | 1 |
| León Díaz, C | 1 |
| Ciancio, SG | 1 |
| Holmes, A | 1 |
| Davidson, LE | 1 |
| Leguen, MA | 1 |
| Scopp, IW | 1 |
| Morgan, FH | 1 |
| Gillette, WB | 1 |
| Fredrics, HJ | 1 |
| Peskin, MJ | 1 |
| Kleinman, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Onset of Action of a Fast Release Aspirin Tablet and Acetaminophen Caplet in Sore Throat Pain[NCT01453400] | Phase 3 | 177 participants (Actual) | Interventional | 2011-09-27 | Completed | ||
| Comparative Onset of Action of a Fast Release Aspirin Tablet in a Dental Impaction Pain Model[NCT01420094] | Phase 3 | 510 participants (Actual) | Interventional | 2011-06-16 | Completed | ||
| A Comparison of the Efficacy and Safety of ULTRACET® (Tramadol HCl/Acetaminophen) Versus ULTRAM® (Tramadol HCl) Versus Placebo in Subjects With Pain Following Oral Surgery[NCT00236483] | Phase 4 | 456 participants (Actual) | Interventional | 2002-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for acetaminophen and Toothache
| Article | Year |
|---|---|
Evidence-based clinical practice guideline for the pharmacologic management of acute dental pain in children: A report from the American Dental Association Science and Research Institute, the University of Pittsburgh School of Dental Medicine, and the Cen
Topics: Academies and Institutes; Acetaminophen; Acute Pain; American Dental Association; Anti-Inflammatory | 2023 |
Antibiotic use for irreversible pulpitis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Humans; Ibuprofen; Pain Measurement; | 2013 |
Antibiotic use for irreversible pulpitis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Female; Humans; Ibuprofen; Ma | 2016 |
Evidence-based review of clinical studies on pharmacology (non-anesthetic studies).
Topics: Acetaminophen; Administration, Oral; Analgesics; Anxiety; Dental Pulp Diseases; Dexamethasone; Drug | 2009 |
Pain management: Part 1: Managing acute and postoperative dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Pain | 2010 |
11 trials available for acetaminophen and Toothache
| Article | Year |
|---|---|
Does acetaminophen/hydrocodone affect cold pulpal testing in patients with symptomatic irreversible pulpitis? A prospective, randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal | 2016 |
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal | 2016 |
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal | 2016 |
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal | 2016 |
Effect of narcotic pain reliever on pulp tests in women.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Opioid; Cold Temperature; Cross-Over Studies | 2002 |
A double-blind placebo-controlled comparison of tramadol/acetaminophen and tramadol in patients with postoperative dental pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Dizziness; Double-Bl | 2004 |
Effectiveness of various medications on postoperative pain following complete instrumentation.
Topics: Acetaminophen; Adult; Analysis of Variance; Chi-Square Distribution; Codeine; Dental Anxiety; Erythr | 1994 |
A comparison of ketorolac tromethamine and acetaminophen codeine in the management of acute apical periodontitis.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti- | 1999 |
Change in pain threshold by meperidine, naproxen sodium, and acetaminophen as determined by electric pulp testing.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inf | 1998 |
Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents; Anti-I | 2000 |
[Evaluation of a new analgesic combination in the control of pain in different odontological processes].
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Caffeine; Clinical Trials as Topic; Dextropropoxyphene | 1976 |
Single-blind clinical trial comparing use of fentiazac and paracetamol in postendodontic periodontitis.
Topics: Acetaminophen; Acetates; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical | 1985 |
Dialog. A double-blind clinical study of dialog, darvon and a placebo in the management of postoperative dental pain.
Topics: Acetaminophen; Barbiturates; Clinical Trials as Topic; Pain; Postoperative Care; Surgery, Oral; Toot | 1967 |
22 other studies available for acetaminophen and Toothache
| Article | Year |
|---|---|
Supra-Therapeutic Oral Paracetamol Overdose in Adults: An Update for the Dental Team.
Topics: Acetaminophen; Administration, Topical; Adult; Algorithms; Analgesics, Non-Narcotic; Drug Overdose; | 2017 |
Dental pain management - a cause of significant morbidity due to paracetamol overdose.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Child; Child, Preschool; Drug Over | 2018 |
Self-medication for dental pain is a major cause of accidental overdose.
Topics: Acetaminophen; Drug Overdose; Humans; Pain Management; Substance-Related Disorders; Toothache | 2018 |
Overdose due to dental pain.
Topics: Acetaminophen; Drug Overdose; Humans; Pain Management; Toothache | 2018 |
Pharmacology: Paracetamol prescribing.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Prescriptions; Humans; Pain Management; Toothache | 2018 |
Pharmacology: inflammatory definitions.
Topics: Acetaminophen; Anti-Inflammatory Agents; Humans; Inflammation; Terminology as Topic; Toothache | 2014 |
Summary of: Paracetamol overdose secondary to dental pain: a case series.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Overdose; Female; Humans; Male; Pain Management; Tooth | 2015 |
Paracetamol overdose secondary to dental pain: a case series.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Drug Overdose; England; Female; Hospital | 2015 |
Dental pain as a risk factor for accidental acetaminophen overdose: a case-control study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Case-Control St | 2011 |
Unintentional overdose of analgesia secondary to acute dental pain.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, | 2002 |
An update on analgesics for the management of acute postoperative dental pain.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, | 2002 |
[Acute pancreatitis induced by codeine-acetaminophen association: report of two cases].
Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Em | 2003 |
Nonprescription dental pain relief.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; | 2004 |
Paracetamol overdose as a result of dental pain requiring medical treatment - two case reports.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Antidotes; Chemical and Drug Ind | 2007 |
The efficacy of self-prescribed analgesics in the treatment of toothache.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Female; Humans; Male; Self Medication; Toothache | 1983 |
Evaluation of acetaminophen and aspirin in the relief of preoperative dental pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Female; Humans; Male; Middle Aged; Mouth Diseases; | 1980 |
Self-medication for the control of dental pain: what are our patients taking?
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Aspirin; Chi-Square Distribution; Codeine; Consu | 1994 |
Bullous fixed drug eruption due to paracetamol with an unusual immunofluorescence pattern.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Basement Membrane; Complement C3; Drug Eruptions; Fem | 1998 |
Prescribing limitations.
Topics: Acetaminophen; Analgesics, Opioid; Codeine; Drug Combinations; Drug Prescriptions; Formularies as To | 2001 |
Pain control in endodontics.
Topics: Acetaminophen; Analgesics; Aspirin; Cellulitis; Codeine; Dextropropoxyphene; Humans; Nausea; Pain; P | 1979 |
Acetaminophen as an analgesic.
Topics: Acetaminophen; Humans; Toothache | 1990 |
Reye's syndrome and analgesic choice in dentistry.
Topics: Acetaminophen; Aspirin; Attitude; Child; Child, Preschool; Female; Health Education; Humans; Infant; | 1989 |