Page last updated: 2024-10-22

acetaminophen and Thyroid Diseases

acetaminophen has been researched along with Thyroid Diseases in 2 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Thyroid Diseases: Pathological processes involving the THYROID GLAND.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oltman, J1
Militsakh, O1
D'Agostino, M1
Kauffman, B1
Lindau, R1
Coughlin, A1
Lydiatt, W1
Lydiatt, D1
Smith, R1
Panwar, A1
Forfar, JC1
Pottage, A1
Toft, AD1
Irvine, WJ1
Clements, JA1
Prescott, LF1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Optimization of Opioid Discharge Prescriptions Following Thyroid and Parathyroid Surgeries[NCT04955444]240 participants (Actual)Interventional2021-06-14Completed
Post-operative Pain Control With Acetaminophen and Ibuprofen After Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: a Prospective Study.[NCT05287217]60 participants (Anticipated)Interventional2022-07-29Not yet recruiting
Use of Single Dose Pre-Operative Pregabalin for Post-Operative Analgesia in Bilateral Head and Neck Cancer Surgery: A Randomized, Double-Blinded, Placebo-Controlled Trial[NCT03714867]Phase 40 participants (Actual)Interventional2019-03-22Withdrawn (stopped due to Inability to recruit patients)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

New Opioid Discharge Prescriptions

Proportion of patients who receive new opioid discharge prescriptions at discharge following a thyroidectomy or parathyroidectomy procedure. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group128
Post-implementation Group28

New Opioid Prescriptions From the Surgeon's Office Within 7 Days of Surgery

Proportion of thyroidectomy and parathyroidectomy postoperative patients who receive new opioid prescriptions from the surgeon's office within 7 days of surgery including discharge prescriptions. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 7 days

InterventionParticipants (Count of Participants)
Historical Control Group0
Post-implementation Group0

Opioid Discharge Prescriptions Exceeding 112.5 Oral Morphine Milligram Equivalents (MMEs)

Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding the recommended dose of 112.5 oral MMEs (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group52
Post-implementation Group8

Opioid Discharge Prescriptions Exceeding 5 Days

Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding 5 days of therapy (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group27
Post-implementation Group5

Opioid Prescriptions Exceeding 50 Oral MMEs/Day When New Discharge Prescriptions Are Added to Existing Opioid Therapy

Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid prescriptions exceeding 50 oral MMEs/day when new, postoperative discharge prescriptions are added to existing opioid therapy (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group9
Post-implementation Group0

Other Studies

2 other studies available for acetaminophen and Thyroid Diseases

ArticleYear
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
    JAMA otolaryngology-- head & neck surgery, 2017, 12-01, Volume: 143, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti

2017
Paracetamol pharmacokinetics in thyroid disease.
    European journal of clinical pharmacology, 1980, Volume: 18, Issue:3

    Topics: Acetaminophen; Adult; Aged; Female; Humans; Hyperthyroidism; Hypothyroidism; Kinetics; Male; Middle

1980