acetaminophen has been researched along with Tension-Type Headache in 40 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Tension-Type Headache: A common primary headache disorder, characterized by a dull, non-pulsatile, diffuse, band-like (or vice-like) PAIN of mild to moderate intensity in the HEAD; SCALP; or NECK. The subtypes are classified by frequency and severity of symptoms. There is no clear cause even though it has been associated with MUSCLE CONTRACTION and stress. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We sought to compare the efficacy and safety profiles of aspirin, acetaminophen with codeine, and placebo in the treatment of post-operative dental pain and tension-type headache." | 9.16 | Assessment of the efficacy and safety profiles of aspirin and acetaminophen with codeine: results from 2 randomized, controlled trials in individuals with tension-type headache and postoperative dental pain. ( Fisher, M; Gatoulis, SC; Voelker, M, 2012) |
| "The main aim of this study was to confirm in an Italian population affected by tension-type headache (TTH) the good profile of safety and tolerability of the combination paracetamol 1,000 mg-caffeine 130 mg (PCF) observed in previous studies, by a comparison with naproxen sodium 550 mg (NAP) and placebo (PLA)." | 9.13 | Tolerability and efficacy of a combination of paracetamol and caffeine in the treatment of tension-type headache: a randomised, double-blind, double-dummy, cross-over study versus placebo and naproxen sodium. ( Del Bene, E; Di Loreto, G; Di Trapani, G; Dionisio, P; Granella, F; LaPegna, G; Pini, LA; Prudenzano, MP; Sarchielli, P; Savi, L; Zanchin, G, 2008) |
| "To assess the efficacy and safety of aspirin for acute treatment of episodic tension-type headache (TTH) in adults compared with placebo or any active comparator." | 8.95 | Aspirin for acute treatment of episodic tension-type headache in adults. ( Derry, S; Moore, RA; Wiffen, PJ, 2017) |
| "Ibuprofen 400 mg provides an important benefit in terms of being pain free at 2 hours for a small number of people with frequent episodic tension-type headache who have an acute headache with moderate or severe initial pain." | 8.91 | Ibuprofen for acute treatment of episodic tension-type headache in adults. ( Bendtsen, L; Derry, S; Moore, RA; Wiffen, PJ, 2015) |
| "The combination of acetylsalicylic acid, acetaminophen and caffeine is effective and well tolerated in episodic tension-type headache, and significantly superior to acetaminophen with regard to being pain-free at 2 h, headache response at 2 h and ability to return to daily activities, even in those with pain rated severe at baseline." | 8.90 | Use of a fixed combination of acetylsalicylic acid, acetaminophen and caffeine compared with acetaminophen alone in episodic tension-type headache: meta-analysis of four randomized, double-blind, placebo-controlled, crossover studies. ( Diener, HC; Gold, M; Hagen, M, 2014) |
| "Ibuprofen was associated with a lower likelihood of the occurrence of any events and gastrointestinal adverse events compared with placebo and paracetamol (OR: 0." | 7.01 | Paracetamol versus ibuprofen in treating episodic tension-type headache: a systematic review and network meta-analysis. ( Albunaian, N; Alfehaid, M; Alhamoud, M; Alhumrran, H; Alnasser, A; Ferwana, M, 2023) |
| " There was no significant difference among the treatment groups in the incidence of adverse events (P=0." | 6.70 | Efficacy and safety of acetaminophen and naproxen in the treatment of tension-type headache. A randomized, double-blind, placebo-controlled trial. ( Bowen, DL; Cooper, KM; May, LG; Prior, MJ, 2002) |
| " Additional studies are needed to assess the relationship between caffeine dosing and clinical benefits in patients with TTH and migraine." | 6.55 | Caffeine in the management of patients with headache. ( Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS, 2017) |
| "We sought to compare the efficacy and safety profiles of aspirin, acetaminophen with codeine, and placebo in the treatment of post-operative dental pain and tension-type headache." | 5.16 | Assessment of the efficacy and safety profiles of aspirin and acetaminophen with codeine: results from 2 randomized, controlled trials in individuals with tension-type headache and postoperative dental pain. ( Fisher, M; Gatoulis, SC; Voelker, M, 2012) |
| "The results of this subgroup analysis confirm that the fixed combination of ASA (250 mg), paracetamol (200 mg), and caffeine (50 mg) is effective and well tolerated in a broad spectrum from mild to severe migraine and tension-type headache severity independently of the headache diagnosis." | 5.15 | The efficacy and tolerability of a fixed combination of acetylsalicylic acid, paracetamol, and caffeine in patients with severe headache: a post-hoc subgroup analysis from a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel g ( Aicher, B; Diener, HC; Peil, H, 2011) |
| " In a randomized double-blind study including individuals with either migraine or tension-type headache (TTH) we showed significant superiority of the fixed combination of acetylsalicylic acid + paracetamol + caffeine over the combination without caffeine, the single preparations, and placebo in the treatment of headache." | 5.14 | Headache classification by history has only limited predictive value for headache episodes treated in controlled trials with OTC analgesics. ( Aicher, B; Diener, HC; Lipton, RB; Pageler, L; Peil, H; Pfaffenrath, V, 2009) |
| "The main aim of this study was to confirm in an Italian population affected by tension-type headache (TTH) the good profile of safety and tolerability of the combination paracetamol 1,000 mg-caffeine 130 mg (PCF) observed in previous studies, by a comparison with naproxen sodium 550 mg (NAP) and placebo (PLA)." | 5.13 | Tolerability and efficacy of a combination of paracetamol and caffeine in the treatment of tension-type headache: a randomised, double-blind, double-dummy, cross-over study versus placebo and naproxen sodium. ( Del Bene, E; Di Loreto, G; Di Trapani, G; Dionisio, P; Granella, F; LaPegna, G; Pini, LA; Prudenzano, MP; Sarchielli, P; Savi, L; Zanchin, G, 2008) |
| "We investigated efficacy, safety, and tolerability of two tablets of the fixed combination of 250 mg acetylsalicylic acid (ASA) + 200 mg paracetamol + 50 mg caffeine (Thomapyrin) in comparison with two tablets of 250 mg ASA + 200 mg paracetamol, two tablets of 500 mg ASA, two tablets of 500 mg paracetamol, two tablets of 50 mg caffeine, and placebo in patients who were used to treating their episodic tension-type headache or migraine attacks with non-prescription analgesics." | 5.11 | The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group st ( Aicher, B; Diener, HC; Pageler, L; Peil, H; Pfaffenrath, V, 2005) |
| "Six randomized, double-blind, two-period crossover studies, conducted under similar protocols, compared the efficacy of two analgesic combinations containing caffeine with an acetaminophen 1000 mg control and with a placebo in outpatients with episodic tension-type headaches." | 5.07 | Caffeine as an analgesic adjuvant in tension headache. ( Armellino, JJ; Beaver, WT; Friedman, M; Gillings, DB; Migliardi, JR, 1994) |
| "To assess the efficacy and safety of aspirin for acute treatment of episodic tension-type headache (TTH) in adults compared with placebo or any active comparator." | 4.95 | Aspirin for acute treatment of episodic tension-type headache in adults. ( Derry, S; Moore, RA; Wiffen, PJ, 2017) |
| "Ibuprofen 400 mg provides an important benefit in terms of being pain free at 2 hours for a small number of people with frequent episodic tension-type headache who have an acute headache with moderate or severe initial pain." | 4.91 | Ibuprofen for acute treatment of episodic tension-type headache in adults. ( Bendtsen, L; Derry, S; Moore, RA; Wiffen, PJ, 2015) |
| "The combination of acetylsalicylic acid, acetaminophen and caffeine is effective and well tolerated in episodic tension-type headache, and significantly superior to acetaminophen with regard to being pain-free at 2 h, headache response at 2 h and ability to return to daily activities, even in those with pain rated severe at baseline." | 4.90 | Use of a fixed combination of acetylsalicylic acid, acetaminophen and caffeine compared with acetaminophen alone in episodic tension-type headache: meta-analysis of four randomized, double-blind, placebo-controlled, crossover studies. ( Diener, HC; Gold, M; Hagen, M, 2014) |
| " Most of these patients suffer from migraine, tension-type headache, or a combination of the two; they tend to self-medicate using over the counter combination headache preparations, particularly acetylsalicyclic acid (ASA) and acetaminophen coformulated with caffeine, which is one of the most commonly used combination analgesics in these patients worldwide." | 4.86 | Efficacy of fixed combinations of acetylsalicyclic acid, acetaminophen and caffeine in the treatment of idiopathic headache: a review. ( Anneken, K; Evers, S; Husstedt, IW, 2010) |
| "Though all non-narcotic analgesics have equivalent efficacy against tension-type headache, ibuprofen's generally favorable side-effect profile makes it a reasonable first choice." | 4.83 | Is any one analgesic superior for episodic tension-type headache? ( Berger, MY; Damen, L; Koes, BW; Merlijn, V; Passchier, J; Verhagen, AP, 2006) |
| " For the acute treatment of migraine attacks or tension-type headache, ibuprofen (10 mg per kg body weight) or acetaminophen (15 mg per kg body weight) are recommended with highest evidence, intranasal sumatriptan (10 to 20 mg) can be given as second choice." | 4.81 | [Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)]. ( Evers, S; Gerber, WD; Naumann, E; Pothmann, R; Uberall, M, 2002) |
| "Ibuprofen was associated with a lower likelihood of the occurrence of any events and gastrointestinal adverse events compared with placebo and paracetamol (OR: 0." | 3.01 | Paracetamol versus ibuprofen in treating episodic tension-type headache: a systematic review and network meta-analysis. ( Albunaian, N; Alfehaid, M; Alhamoud, M; Alhumrran, H; Alnasser, A; Ferwana, M, 2023) |
| "We extracted pain and adverse events outcomes from 36 systematic reviews that assessed the efficacy of paracetamol in 44 painful conditions." | 2.72 | The efficacy and safety of paracetamol for pain relief: an overview of systematic reviews. ( Abdel Shaheed, C; Ahedi, H; Day, RO; Dmitritchenko, A; Ferreira, GE; Kamper, S; Langendyk, V; Latimer, J; Lin, C; Maher, CG; McLachlan, AJ; McLachlan, H; Saragiotto, B; Stanaway, F, 2021) |
| " There was no significant difference among the treatment groups in the incidence of adverse events (P=0." | 2.70 | Efficacy and safety of acetaminophen and naproxen in the treatment of tension-type headache. A randomized, double-blind, placebo-controlled trial. ( Bowen, DL; Cooper, KM; May, LG; Prior, MJ, 2002) |
| " Additional studies are needed to assess the relationship between caffeine dosing and clinical benefits in patients with TTH and migraine." | 2.55 | Caffeine in the management of patients with headache. ( Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS, 2017) |
| "The TACs include cluster headache, paroxysmal hemicrania, and short-lasting neuralgiform headache attacks with conjunctival injection and tearing; hemicrania continua, although classified separately by the International Headache Society, shares many features of both migraine and the TACs." | 2.49 | Primary headache disorders. ( Benoliel, R; Eliav, E, 2013) |
| "The fixed dose combination of ibuprofen and paracetamol provides faster and long-term anaesthesia with a comparatively lower dosage of each analgesic." | 1.62 | [Clinical and pharmacological approaches to the choice of a drug for a tension-type headache relief]. ( Khaytovich, ED; Perkov, AV; Shikh, EV, 2021) |
| "The main migraine trigger was stress or anxiety; 86." | 1.51 | Migraine, tension-type headache, and depression among Saudi female students in Taif University. ( Desouky, DE; Taha, AA; Zaid, HA, 2019) |
| "Headache is a common complaint among Nigerian undergraduate students and it limits the daily activity of majority of the sufferers." | 1.46 | Prevalence and clinical characteristics of headaches among undergraduate students in three tertiary institutions in Ilorin, Nigeria. ( Aderibigbe, SA; Adeyanju, OA; Desalu, OO; Kolo, PM; Mustapha, AF; Sanya, EO, 2017) |
| "The headache disorders, namely, migraine and tension type headache and the associated analgesic consumption is badly underestimated and thus makes a major current public health problem." | 1.43 | Management of headache and associated factors among undergraduate medicine and health science students of University of Gondar, North West Ethiopia. ( Abay, Z; Abdelwuhab, M; Basazn, A; Birru, EM; Sirak, B; Teni, FS, 2016) |
| "The corresponding values for tension headache and controls were 0." | 1.30 | Platelet sulphotransferase activity, plasma sulphate levels and sulphation capacity in patients with migraine and tension headache. ( Alam, Z; Coombes, N; Steventon, GB; Waring, RH; Williams, AC, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (15.00) | 18.2507 |
| 2000's | 12 (30.00) | 29.6817 |
| 2010's | 17 (42.50) | 24.3611 |
| 2020's | 5 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Shikh, EV | 1 |
| Khaytovich, ED | 1 |
| Perkov, AV | 1 |
| Katsuki, M | 1 |
| Matsumori, Y | 1 |
| Kashiwagi, K | 1 |
| Kawamura, S | 1 |
| Koh, A | 1 |
| Alnasser, A | 1 |
| Alhumrran, H | 1 |
| Alfehaid, M | 1 |
| Alhamoud, M | 1 |
| Albunaian, N | 1 |
| Ferwana, M | 1 |
| Cankaya, S | 1 |
| Oktem, EO | 1 |
| Saatci, O | 1 |
| Velioglu, HA | 1 |
| Uygur, AB | 1 |
| Ozsimsek, A | 1 |
| Hanoglu, L | 1 |
| Yulug, B | 1 |
| Abdel Shaheed, C | 1 |
| Ferreira, GE | 1 |
| Dmitritchenko, A | 1 |
| McLachlan, AJ | 1 |
| Day, RO | 1 |
| Saragiotto, B | 1 |
| Lin, C | 1 |
| Langendyk, V | 1 |
| Stanaway, F | 1 |
| Latimer, J | 1 |
| Kamper, S | 1 |
| McLachlan, H | 1 |
| Ahedi, H | 1 |
| Maher, CG | 1 |
| Lipton, RB | 2 |
| Diener, HC | 5 |
| Robbins, MS | 1 |
| Garas, SY | 1 |
| Patel, K | 1 |
| Sanya, EO | 1 |
| Desalu, OO | 1 |
| Aderibigbe, SA | 1 |
| Kolo, PM | 1 |
| Mustapha, AF | 1 |
| Adeyanju, OA | 1 |
| Desouky, DE | 1 |
| Zaid, HA | 1 |
| Taha, AA | 1 |
| Benoliel, R | 1 |
| Eliav, E | 1 |
| Gold, M | 1 |
| Hagen, M | 1 |
| Derry, S | 3 |
| Wiffen, PJ | 2 |
| Moore, RA | 3 |
| Bendtsen, L | 1 |
| Göbel, H | 1 |
| Heinze, A | 1 |
| Heinze-Kuhn, K | 1 |
| Göbel, A | 1 |
| Göbel, C | 1 |
| Birru, EM | 1 |
| Abay, Z | 1 |
| Abdelwuhab, M | 1 |
| Basazn, A | 1 |
| Sirak, B | 1 |
| Teni, FS | 1 |
| Stephens, G | 1 |
| Pini, LA | 1 |
| Del Bene, E | 1 |
| Zanchin, G | 1 |
| Sarchielli, P | 1 |
| Di Trapani, G | 1 |
| Prudenzano, MP | 1 |
| LaPegna, G | 1 |
| Savi, L | 1 |
| Di Loreto, G | 1 |
| Dionisio, P | 1 |
| Granella, F | 1 |
| Pfaffenrath, V | 2 |
| Pageler, L | 2 |
| Peil, H | 3 |
| Aicher, B | 3 |
| Alzoubi, KH | 1 |
| Mhaidat, N | 1 |
| Azzam, SA | 1 |
| Khader, Y | 1 |
| Salem, S | 1 |
| Issaifan, H | 1 |
| Haddadin, R | 1 |
| Anneken, K | 1 |
| Evers, S | 2 |
| Husstedt, IW | 1 |
| Manzano, S | 1 |
| Doyon-Trottier, E | 1 |
| Bailey, B | 1 |
| Haag, G | 2 |
| Verhagen, AP | 2 |
| Damen, L | 2 |
| Berger, MY | 2 |
| Lenssinck, ML | 1 |
| Passchier, J | 2 |
| Kroes, BW | 1 |
| Gatoulis, SC | 1 |
| Voelker, M | 2 |
| Fisher, M | 1 |
| Kormos, W | 1 |
| Prior, MJ | 1 |
| Cooper, KM | 1 |
| May, LG | 1 |
| Bowen, DL | 1 |
| Steiner, TJ | 2 |
| Lange, R | 2 |
| Lussier, MT | 1 |
| Richard, C | 1 |
| Merlijn, V | 1 |
| Koes, BW | 1 |
| Migliardi, JR | 1 |
| Armellino, JJ | 1 |
| Friedman, M | 1 |
| Gillings, DB | 1 |
| Beaver, WT | 1 |
| Schachtel, BP | 1 |
| Furey, SA | 1 |
| Thoden, WR | 1 |
| Alam, Z | 1 |
| Coombes, N | 1 |
| Waring, RH | 1 |
| Williams, AC | 1 |
| Steventon, GB | 1 |
| Amelin, AV | 1 |
| Sorokoumov, VA | 1 |
| Rabello, GD | 1 |
| Forte, LV | 1 |
| Galvão, AC | 1 |
| Mehlisch, DR | 1 |
| Weaver, M | 1 |
| Fladung, B | 1 |
| Pothmann, R | 1 |
| Uberall, M | 1 |
| Naumann, E | 1 |
| Gerber, WD | 1 |
| Calero Muñoz, S | 1 |
| Fariñas Balaguer, O | 1 |
| Nieto Márquez, L | 1 |
| Cobo Guerrero, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acute Headache Treatment in Pregnancy: Improvement in Pain Scores With Occipital Nerve Block vs PO Acetaminophen With Caffeine A Randomized Controlled Trial[NCT03951649] | Phase 4 | 62 participants (Actual) | Interventional | 2020-02-10 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT03951649)
Timeframe: 7 days
| Intervention | days (Median) |
|---|---|
| Occipital Nerve Block | 6 |
| Oral Acetaminophen/Caffeine Group | 1 |
(NCT03951649)
Timeframe: 28 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 9 |
| Oral Acetaminophen/Caffeine Group | 4 |
(NCT03951649)
Timeframe: 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 7 |
| Oral Acetaminophen/Caffeine Group | 2 |
Other: Pain at injection site (NCT03951649)
Timeframe: 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 0 |
| Oral Acetaminophen/Caffeine Group | 2 |
(NCT03951649)
Timeframe: 7 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 0 |
| Oral Acetaminophen/Caffeine Group | 0 |
(NCT03951649)
Timeframe: 4 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 9 |
| Oral Acetaminophen/Caffeine Group | 14 |
(NCT03951649)
Timeframe: 5 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 4 |
| Oral Acetaminophen/Caffeine Group | 2 |
Emergency department for treatment of headache since treatment asked at 28 day follow up (NCT03951649)
Timeframe: 28 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 5 |
| Oral Acetaminophen/Caffeine Group | 1 |
(NCT03951649)
Timeframe: 120 min
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 5 |
| Oral Acetaminophen/Caffeine Group | 5 |
Based on guidelines from the International Headache Society the primary outcome is the portion of women who experience resolution of headache or improvement of headache to mild range (VRS ≤ 3) at 2 hours following treatment with Occipital nerve block as compared to acetaminophen/caffeine cocktail. (NCT03951649)
Timeframe: 60-300 min
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 20 |
| Oral Acetaminophen/Caffeine Group | 16 |
"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 60 min
| Intervention | score on a scale (Median) |
|---|---|
| Occipital Nerve Block | 6 |
| Oral Acetaminophen/Caffeine Group | 3 |
"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 180min
| Intervention | score on a scale (Median) |
|---|---|
| Occipital Nerve Block | 6 |
| Oral Acetaminophen/Caffeine Group | 4 |
"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 2 hrs
| Intervention | score on a scale (Median) |
|---|---|
| Occipital Nerve Block | 6.0 |
| Oral Acetaminophen/Caffeine Group | 6.5 |
16 reviews available for acetaminophen and Tension-Type Headache
| Article | Year |
|---|---|
Paracetamol versus ibuprofen in treating episodic tension-type headache: a systematic review and network meta-analysis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Humans; Ibuprofen; Network Meta-Analysis; Tension-Type Head | 2023 |
The efficacy and safety of paracetamol for pain relief: an overview of systematic reviews.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Case-Control Studies; Craniotomy; Data Management; Humans; | 2021 |
Caffeine in the management of patients with headache.
Topics: Abdominal Pain; Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Central Nervous System Stimulan | 2017 |
Primary headache disorders.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Chronic Disease; Cluster Headache; Cycloox | 2013 |
Use of a fixed combination of acetylsalicylic acid, acetaminophen and caffeine compared with acetaminophen alone in episodic tension-type headache: meta-analysis of four randomized, double-blind, placebo-controlled, crossover studies.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination; Humans | 2014 |
Ibuprofen for acute treatment of episodic tension-type headache in adults.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Cyclooxygenase Inhibitors; Dic | 2015 |
[Peppermint oil in the acute treatment of tension-type headache].
Topics: Acetaminophen; Administration, Cutaneous; Adult; Aspirin; Child; Controlled Clinical Trials as Topic | 2016 |
Paracetamol (acetaminophen) for acute treatment of episodic tension-type headache in adults.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Humans; Pain Measurement; Rand | 2016 |
Aspirin for acute treatment of episodic tension-type headache in adults.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics; Aspirin; Codeine; Dipyrone; Humans; Me | 2017 |
Efficacy of fixed combinations of acetylsalicyclic acid, acetaminophen and caffeine in the treatment of idiopathic headache: a review.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Caffeine; Drug Combinations; Humans; Tens | 2010 |
Myth: Ibuprofen is superior to acetaminophen for the treatment of benign headaches in children and adults.
Topics: Acetaminophen; Adolescent; Adult; Altitude Sickness; Analgesics, Non-Narcotic; Child; Headache; Huma | 2010 |
[Treatment of tension type headache: paracetamol and NSAIDs work: a systematic review].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Humans; Tension-Type Headache; Treatment Out | 2010 |
Is any one analgesic superior for episodic tension-type headache?
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Dos | 2006 |
[Self-medication of migraine and headache].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; | 2006 |
[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)].
Topics: Acetaminophen; Adrenergic beta-Antagonists; Age Factors; Analgesics, Non-Narcotic; Biofeedback, Psyc | 2002 |
[The latest in headache treatment].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Angiotensin-Converting | 2002 |
11 trials available for acetaminophen and Tension-Type Headache
| Article | Year |
|---|---|
Tolerability and efficacy of a combination of paracetamol and caffeine in the treatment of tension-type headache: a randomised, double-blind, double-dummy, cross-over study versus placebo and naproxen sodium.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 2008 |
Headache classification by history has only limited predictive value for headache episodes treated in controlled trials with OTC analgesics.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Caffeine; Double-Blind Me | 2009 |
The efficacy and tolerability of a fixed combination of acetylsalicylic acid, paracetamol, and caffeine in patients with severe headache: a post-hoc subgroup analysis from a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel g
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 2011 |
Assessment of the efficacy and safety profiles of aspirin and acetaminophen with codeine: results from 2 randomized, controlled trials in individuals with tension-type headache and postoperative dental pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Va | 2012 |
Efficacy and safety of acetaminophen and naproxen in the treatment of tension-type headache. A randomized, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Leas | 2002 |
Aspirin in episodic tension-type headache: placebo-controlled dose-ranging comparison with paracetamol.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Dose-Response Relationship, Drug; Double-Blind Meth | 2003 |
The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group st
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; | 2005 |
Caffeine as an analgesic adjuvant in tension headache.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Cross-Over Studies; Double-Blind Method; | 1994 |
Nonprescription ibuprofen and acetaminophen in the treatment of tension-type headache.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Male | 1996 |
Ketoprofen (25 mg) in the symptomatic treatment of episodic tension-type headache: double-blind placebo-controlled comparison with acetaminophen (1000 mg).
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 1998 |
Ketoprofen, acetaminophen, and placebo in the treatment of tension headache.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blin | 1998 |
13 other studies available for acetaminophen and Tension-Type Headache
| Article | Year |
|---|---|
[Clinical and pharmacological approaches to the choice of a drug for a tension-type headache relief].
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Drug Combinations; Humans; Ibuprofen; Tension-T | 2021 |
Efficacy of Kampo medicine Kakkonto as acute medication to treat tension-type headache among musculoskeletal pain patients using regular analgesics.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Female; Humans; Male; Medicine, Kampo; Middle Ag | 2023 |
Paracetamol alters empathy scores in healthy and headache subjects: Functional MRI correlates.
Topics: Acetaminophen; Adult; Brain; Empathy; Female; Headache; Humans; Magnetic Resonance Imaging; Male; Mi | 2020 |
Prevalence and clinical characteristics of headaches among undergraduate students in three tertiary institutions in Ilorin, Nigeria.
Topics: Acetaminophen; Adolescent; Adult; Chronic Disease; Cross-Sectional Studies; Female; Headache; Humans | 2017 |
Migraine, tension-type headache, and depression among Saudi female students in Taif University.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anxiety; Comorbidity; Cross-Sectional Studies; Depre | 2019 |
Management of headache and associated factors among undergraduate medicine and health science students of University of Gondar, North West Ethiopia.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cross-Sectional Studies; Disease Management; Ethiopi | 2016 |
Prevalence of migraine and tension-type headache among adults in Jordan.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Analgesics; Drug-Relate | 2009 |
Comments on 'Efficacy of fixed combinations of acetylsalicylic acid, acetaminophen and caffeine in the treatment of idiopathic headache: a review'.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; | 2010 |
On call. I have a long history of tension headaches and usually get relief by taking acetaminophen. Lately, the medication relieves the headache, but then the pain returns later in the day. Can acetaminophen lose its effectiveness, or could it be somethin
Topics: Acetaminophen; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Drug Tolerance; Health Be | 2012 |
History of current illness.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Diagnosis, Differential; Humans; Male; Medical History Taki | 2004 |
Platelet sulphotransferase activity, plasma sulphate levels and sulphation capacity in patients with migraine and tension headache.
Topics: Acetaminophen; Adult; Arylsulfotransferase; Blood Platelets; Case-Control Studies; Female; Humans; M | 1997 |
[The efficacy of Solpadeine in patients with primary forms of headache].
Topics: Acetaminophen; Adult; Analgesics; Caffeine; Codeine; Drug Combinations; Drug Evaluation; Female; Hum | 1997 |
[Clinical evaluation of the efficacy of the paracetamol and caffeine combination in the treatment of tension headache].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Caffeine; Central Nervous S | 2000 |