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acetaminophen and Substance Withdrawal Syndrome

acetaminophen has been researched along with Substance Withdrawal Syndrome in 17 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.

Research Excerpts

ExcerptRelevanceReference
"To determine which class of non-opioid analgesics - paracetamol (acetaminophen), NSAIDs or COX-2 inhibitors - is the most effective at reducing morphine consumption and associated adverse effects when used as part of multimodal analgesia following major surgery."2.46Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side effects after major surgery: a systematic review. ( Jenkins, B; Maund, E; McDaid, C; Rice, S; Woolacott, N; Wright, K, 2010)
"Midazolam was used in 95 patients (56%), with an average dose of 35 (±14) μg/kg/h."1.51Postsurgery analgesic and sedative drug use in a French neonatal intensive care unit: A single-center retrospective cohort study. ( Benahmed-Canat, A; Canat, G; Claris, O; Kassai, B; Nguyen, KA; Paret, N; Plaisant, F; Rabilloud, M; Riche, B, 2019)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's4 (23.53)18.2507
2000's5 (29.41)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cevoli, S1
Giannini, G1
Favoni, V1
Terlizzi, R1
Sancisi, E1
Nicodemo, M1
Zanigni, S1
Bacchi Reggiani, ML1
Pierangeli, G1
Cortelli, P1
Cock, V1
Edmonds, C1
Cock, C1
Benahmed-Canat, A1
Plaisant, F1
Riche, B1
Rabilloud, M1
Canat, G1
Paret, N1
Claris, O1
Kassai, B1
Nguyen, KA1
Suzuki, Y1
Shinada, K1
Orime, N1
Someya, T1
Kessler, TL1
Vesta, KS1
Blevins, SM1
McDaid, C1
Maund, E1
Rice, S1
Wright, K1
Jenkins, B1
Woolacott, N1
Zhao, P1
Slattery, JT1
Romero, CE1
Baron, JD1
Knox, AP1
Hinchey, JA1
Ropper, AH1
Miller, SC1
Wiener, SW1
Hoffman, RS1
Hoffmeister, F1
Dycka, J1
Rämsch, K1
Golden, NL1
King, KC1
Sokol, RJ1
Hastier, P1
Paolini, O1
Demarquay, JF1
Caroli-Bosc, FX1
Chichmanian, RM1
Saint-Paul, MC1
Delmont, J1
Hawton, K1
Ware, C1
Mistry, H1
Hewitt, J1
Kingsbury, S1
Roberts, D1
Weitzel, H1
Sinclair, J1
Jeffery, E1
Wrighton, S1
Kostrubsky, V1
Szakacs, J1
Wood, S1
Sinclair, P1
Leuzinger, D1
Lesser, PB1
Vietti, MM1
Clark, WD1

Reviews

3 reviews available for acetaminophen and Substance Withdrawal Syndrome

ArticleYear
Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side effects after major surgery: a systematic review.
    Health technology assessment (Winchester, England), 2010, Volume: 14, Issue:17

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St

2010
Trends in clinical toxicology: advances that may change your practice.
    Basic & clinical pharmacology & toxicology, 2005, Volume: 97, Issue:1

    Topics: Acetaminophen; Anticoagulants; Charcoal; Chest Pain; Cocaine-Related Disorders; Ethanol; Humans; Poi

2005
Alcohol-mediated increases in acetaminophen hepatotoxicity: role of CYP2E and CYP3A.
    Biochemical pharmacology, 1998, May-15, Volume: 55, Issue:10

    Topics: Acetaminophen; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2E1; C

1998

Trials

2 trials available for acetaminophen and Substance Withdrawal Syndrome

ArticleYear
Treatment of withdrawal headache in patients with medication overuse headache: a pilot study.
    The journal of headache and pain, 2017, Volume: 18, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Drug Therapy, Combination; Female; Glucocorticoids;

2017
Paracetamol self-poisoning. Characteristics, prevention and harm reduction.
    The British journal of psychiatry : the journal of mental science, 1996, Volume: 168, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Delayed-Action Preparation

1996

Other Studies

12 other studies available for acetaminophen and Substance Withdrawal Syndrome

ArticleYear
Complications related to chronic supratherapeutic use of codeine containing compound analgesics in a cohort of patients presenting for codeine withdrawal.
    Drug and alcohol review, 2018, Volume: 37, Issue:6

    Topics: Acetaminophen; Acidosis, Renal Tubular; Adult; Analgesics; Anemia; Codeine; Drug Combinations; Femal

2018
Postsurgery analgesic and sedative drug use in a French neonatal intensive care unit: A single-center retrospective cohort study.
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2019, Volume: 26, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cohort Studies; Drug Utilization; Femal

2019
Late-onset delirium after an overdose of acetaminophen in a case of benzodiazepine dependence.
    The Journal of neuropsychiatry and clinical neurosciences, 2013,Fall, Volume: 25, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Benzodiazepines; Delirium; Drug Overdose; Humans; Ma

2013
Resolution of chronic daily headache after acetaminophen discontinuation.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Drug Tolerance; Headache

2009
Effects of ethanol dose and ethanol withdrawal on rat liver mitochondrial glutathione: implication of potentiated acetaminophen toxicity in alcoholics.
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:12

    Topics: Acetaminophen; Alcoholism; Animals; Dose-Response Relationship, Drug; Ethanol; Glutathione; Male; Mi

2002
Barbiturate withdrawal following Internet purchase of Fioricet.
    Archives of neurology, 2004, Volume: 61, Issue:7

    Topics: Acetaminophen; Adult; Barbiturates; Caffeine; Drug Combinations; Female; Humans; Internet; Substance

2004
Coricidin HBP cough and cold addiction.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2005, Volume: 44, Issue:6

    Topics: Acetaminophen; Adolescent; Animals; Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Com

2005
Intragastric self-administration in the rhesus monkey: a comparison of the reinforcing effects of codeine, phenacetin and paracetamol.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Acetaminophen; Animals; Codeine; Dose-Response Relationship, Drug; Haplorhini; Humans; Individuality

1980
Propoxyphene and acetaminophen. Possible effects on the fetus.
    Clinical pediatrics, 1982, Volume: 21, Issue:12

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acetaminophen; Dextropropoxyphene; Drug Therap

1982
[Fulminant hepatitis induced by paracetamol at a therapeutic dose favoured by the ingestion of enzyme inducers in a patient with liver cirrhosis].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Depressive D

1995
[The elderly in need].
    Presse medicale (Paris, France : 1983), 1998, Mar-14, Volume: 27, Issue:10

    Topics: Acetaminophen; Aged; Aged, 80 and over; Akathisia, Drug-Induced; Analgesics, Non-Narcotic; Analgesic

1998
Lethal enhancement of therapeutic doses of acetaminophen by alcohol.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:1

    Topics: Acetaminophen; Autopsy; Bacterial Infections; Chemical and Drug Induced Liver Injury; Drug Synergism

1986