acetaminophen has been researched along with Subarachnoid Hemorrhage in 7 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Patients with aneurysmal subarachnoid hemorrhage (SAH) were randomized to receive either ketoprofen, 100 mg, three times a day (ketoprofen group, n = 9) or a weak NSAID, acetaminophen, 1 g, three times a day (acetaminophen group, n = 9) starting immediately after the diagnosis of aneurysmal SAH." | 5.09 | Effects of nonsteroidal anti-inflammatory drugs on hemostasis in patients with aneurysmal subarachnoid hemorrhage. ( Juvela, S; Niemi, T; Randell, T; Rosenberg, P; Tanskanen, P; Taxell, C, 1999) |
| "Severe headaches are common after subarachnoid hemorrhage." | 1.91 | Acute Headache Management for Patients with Subarachnoid Hemorrhage: An International Survey of Health Care Providers. ( Abu-Mowis, Z; Aspide, R; Barlow, B; Bilotta, F; Busl, KM; Citerio, G; Dickinson, K; Gobinathan, A; Lucke-Wold, B; Maciel, CB; Merck, LH; Miao, G; Morris, NA; Peethala, MM; Shan, G, 2023) |
| "Spontaneous aneurysmal subarachnoid hemorrhage (aSAH) recovery may be hampered by delayed cerebral ischemia (DCI)." | 1.91 | Evaluating analgesic medications utilized in the treatment of aneurysmal subarachnoid hemorrhage and association with delayed cerebral ischemia. ( Busl, KM; Desai, A; Eisinger, RS; Lucke-Wold, B; Maciel, CB; Sorrentino, ZA, 2023) |
| "Acupuncture is a promising method in treatment of headaches associated with meningeal sensitivity or irritation, such as migraine or post-dural puncture headache." | 1.51 | Treating Therapy-Resistant Headache After Aneurysmal Subarachnoid Hemorrhage with Acupuncture. ( Dietzel, J; Eck, T; Usichenko, T, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Maciel, CB | 2 |
| Barlow, B | 1 |
| Lucke-Wold, B | 2 |
| Gobinathan, A | 1 |
| Abu-Mowis, Z | 1 |
| Peethala, MM | 1 |
| Merck, LH | 1 |
| Aspide, R | 1 |
| Dickinson, K | 1 |
| Miao, G | 1 |
| Shan, G | 1 |
| Bilotta, F | 1 |
| Morris, NA | 1 |
| Citerio, G | 1 |
| Busl, KM | 2 |
| Sorrentino, ZA | 1 |
| Desai, A | 1 |
| Eisinger, RS | 1 |
| Dietzel, J | 1 |
| Eck, T | 1 |
| Usichenko, T | 1 |
| Muroi, C | 1 |
| Hugelshofer, M | 1 |
| Seule, M | 1 |
| Keller, E | 1 |
| Fernandez, A | 1 |
| Schmidt, JM | 1 |
| Claassen, J | 1 |
| Pavlicova, M | 1 |
| Huddleston, D | 1 |
| Kreiter, KT | 1 |
| Ostapkovich, ND | 1 |
| Kowalski, RG | 1 |
| Parra, A | 1 |
| Connolly, ES | 1 |
| Mayer, SA | 1 |
| Ducros, A | 1 |
| Niemi, T | 1 |
| Tanskanen, P | 1 |
| Taxell, C | 1 |
| Juvela, S | 1 |
| Randell, T | 1 |
| Rosenberg, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Bromocriptine to Reduce Body Temperature in Febrile Critically-ill Adults With Acute Neurologic Disease: an Open-label, Blinded Endpoint, Randomized Controlled Trial[NCT03496545] | Phase 1/Phase 2 | 47 participants (Actual) | Interventional | 2018-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Mean total body temperature burden above 37°C over 48 hours during which patient receives either control or intervention medication. (NCT03496545)
Timeframe: over 48 hours
| Intervention | Temperature in degrees Celsius (Mean) |
|---|---|
| Acetaminophen | 37.8 |
| Bromocriptine and Acetaminophen | 37.7 |
Time in minutes where the temperature is ≥ 38.3ºC during the 48 hours of control versus intervention administration. (NCT03496545)
Timeframe: 48 hours
| Intervention | Minutes (Mean) |
|---|---|
| Acetaminophen | 216 |
| Bromocriptine and Acetaminophen | 300 |
Time in minutes it took after medication administration for the temperature to reach < 37.5ºC. (NCT03496545)
Timeframe: 48 hours
| Intervention | Minutes (Mean) |
|---|---|
| Acetaminophen | 253.5 |
| Bromocriptine and Acetaminophen | 556 |
Episodes of symptomatic hypotension, including decrease in supine systolic and diastolic pressures of greater than 20mm and 10mm Hg respectively with patient reported accompanying symptoms of light headedness or dizziness and incidence of nausea and headache. (NCT03496545)
Timeframe: Nursing assessment at every shift during 48 hour study period after first drug administration
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Decrease in blood pressure | Nausea | Headache | |
| Acetaminophen | 12 | 2 | 8 |
| Bromocriptine and Acetaminophen | 17 | 3 | 12 |
1 review available for acetaminophen and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
[Acute and chronic headaches].
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2006 |
1 trial available for acetaminophen and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Effects of nonsteroidal anti-inflammatory drugs on hemostasis in patients with aneurysmal subarachnoid hemorrhage.
Topics: Acetaminophen; Adenosine Diphosphate; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antithrombin I | 1999 |
5 other studies available for acetaminophen and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Acute Headache Management for Patients with Subarachnoid Hemorrhage: An International Survey of Health Care Providers.
Topics: Acetaminophen; Analgesics, Opioid; Cross-Sectional Studies; Headache; Health Personnel; Humans; Suba | 2023 |
Evaluating analgesic medications utilized in the treatment of aneurysmal subarachnoid hemorrhage and association with delayed cerebral ischemia.
Topics: Acetaminophen; Aged; Analgesics; Brain Ischemia; Cerebral Infarction; Female; Humans; Male; Middle A | 2023 |
Treating Therapy-Resistant Headache After Aneurysmal Subarachnoid Hemorrhage with Acupuncture.
Topics: Acetaminophen; Acupuncture Therapy; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Dipy | 2019 |
The impact of nonsteroidal anti-inflammatory drugs on inflammatory response after aneurysmal subarachnoid hemorrhage.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; C-Rea | 2014 |
Fever after subarachnoid hemorrhage: risk factors and impact on outcome.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Body Temperature; Brain; Cerebral Hemorrhage; Cognition Dis | 2007 |