acetaminophen has been researched along with Spinal Muscular Atrophies of Childhood in 1 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Spinal Muscular Atrophies of Childhood: A group of recessive inherited diseases that feature progressive muscular atrophy and hypotonia. They are classified as type I (Werdnig-Hoffman disease), type II (intermediate form), and type III (Kugelberg-Welander disease). Type I is fatal in infancy, type II has a late infantile onset and is associated with survival into the second or third decade. Type III has its onset in childhood, and is slowly progressive. (J Med Genet 1996 Apr:33(4):281-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We determined acetaminophen protein adduct levels, in combination with a literature review and systematic evaluation of the cases, using the Roussel Uclaf Causality Assessment Method for drug-induced liver injury to assess causality between recommended acetaminophen dosing and acute liver failure in two children with myopathies." | 1.37 | Acute liver failure after recommended doses of acetaminophen in patients with myopathies. ( Ceelie, I; de Wildt, SN; Gijsen, V; Ito, S; James, LP; Koren, G; Mathot, RA; Tesselaar, CD; Tibboel, D, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ceelie, I | 1 |
| James, LP | 1 |
| Gijsen, V | 1 |
| Mathot, RA | 1 |
| Ito, S | 1 |
| Tesselaar, CD | 1 |
| Tibboel, D | 1 |
| Koren, G | 1 |
| de Wildt, SN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658] | Phase 4 | 48 participants (Anticipated) | Interventional | 2019-02-18 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for acetaminophen and Spinal Muscular Atrophies of Childhood
| Article | Year |
|---|---|
Acute liver failure after recommended doses of acetaminophen in patients with myopathies.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Female; Humans; Intensive Care Units, Pe | 2011 |