acetaminophen has been researched along with Spinal Diseases in 13 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Spinal Diseases: Diseases involving the SPINE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized, placebo-controlled, double-blind study to evaluate the effect of intravenously (IV) administered acetaminophen on postoperative pain in children and adolescents undergoing surgery for idiopathic scoliosis or spondylolisthesis." | 5.16 | Acetaminophen improves analgesia but does not reduce opioid requirement after major spine surgery in children and adolescents. ( Hartikainen, T; Helenius, I; Hiller, A; Kaukonen, M; Korpela, R; Meretoja, OA; Neuvonen, PJ; Nurmi, E; Taivainen, T, 2012) |
| "Tramadol was more effective in the treatment of postoperative pain after lumbar disc surgery." | 2.80 | Comparison of the analgesic effects of paracetamol and tramadol in lumbar disc surgery. ( Çaglar Torun, A; Kelsaka, E; Köksal, E; Kuruoğlu, E; Sarihasan, BB; Taş, N; Yilmaz, MZ, 2015) |
| " The two drugs were found to have the same efficiency on the subjective parameters but high bioavailability glaphenine seems to have an effectiveness in the range of articulatory movements, which is not found with paracetamol." | 2.66 | Comparative study of high bio-availability glaphenine and paracetamol in cervical and lumbar arthrosis. ( Albert, A; Crielaard, JM; Franchimont, P; Urbin Choffray, D, 1987) |
| "Spontaneous pneumomediastinum is an uncommon condition in athletes." | 2.45 | Spontaneous pneumomediastinum and epidural pneumatosis in an adolescent precipitated by weight lifting: a case report and review. ( Patel, DR; Pejka, S; Sadarangani, S, 2009) |
| " The non-steroid antirheumatic benoxaprofen was used alone in a dosage of a 1 x 600 mg tablet daily." | 1.26 | [Benoxaprofen in the treatment of spondylosis and spondylarthrosis (author's transl)]. ( Hevelke, G; Schilling, E, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Maheshwari, K | 1 |
| Avitsian, R | 1 |
| Sessler, DI | 1 |
| Makarova, N | 1 |
| Tanios, M | 1 |
| Raza, S | 1 |
| Traul, D | 1 |
| Rajan, S | 1 |
| Manlapaz, M | 1 |
| Machado, S | 1 |
| Krishnaney, A | 1 |
| Machado, A | 1 |
| Rosenquist, R | 1 |
| Kurz, A | 1 |
| Mathiesen, O | 1 |
| Dahl, B | 1 |
| Thomsen, BA | 1 |
| Kitter, B | 1 |
| Sonne, N | 1 |
| Dahl, JB | 1 |
| Kehlet, H | 1 |
| Devin, CJ | 1 |
| McGirt, MJ | 1 |
| Yilmaz, MZ | 1 |
| Sarihasan, BB | 1 |
| Kelsaka, E | 1 |
| Taş, N | 1 |
| Çaglar Torun, A | 1 |
| Köksal, E | 1 |
| Kuruoğlu, E | 1 |
| Sadarangani, S | 1 |
| Patel, DR | 1 |
| Pejka, S | 1 |
| Reddi, AS | 1 |
| Kunadi, AR | 1 |
| Hiller, A | 1 |
| Helenius, I | 1 |
| Nurmi, E | 1 |
| Neuvonen, PJ | 1 |
| Kaukonen, M | 1 |
| Hartikainen, T | 1 |
| Korpela, R | 1 |
| Taivainen, T | 1 |
| Meretoja, OA | 1 |
| Nowicki, PD | 1 |
| Vanderhave, KL | 1 |
| Gibbons, K | 1 |
| Haydar, B | 1 |
| Seeley, M | 1 |
| Kozlow, K | 1 |
| Bhoopal, K | 1 |
| Gauger, VT | 1 |
| PANTLITSCHKO, L | 1 |
| Federman, AD | 1 |
| Litke, A | 1 |
| Morrison, RS | 1 |
| Hevelke, G | 1 |
| Schilling, E | 1 |
| Urbin Choffray, D | 1 |
| Crielaard, JM | 1 |
| Albert, A | 1 |
| Franchimont, P | 1 |
| Baumann, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Opioid-Free Intravenous Anesthesia for Patients With Joint Hypermobility Syndrome Undergoing Craneo-Cervical Fixation: A Case-series Study Focused on Anti-hyperalgesic Approach[NCT04437589] | 42 participants (Actual) | Observational | 2018-09-06 | Completed | |||
| Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery (IGNITE-AIS Study)[NCT04931433] | Phase 4 | 102 participants (Anticipated) | Interventional | 2020-12-24 | Recruiting | ||
| A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty[NCT03498261] | Phase 1 | 50 participants (Actual) | Interventional | 2018-01-30 | Active, not recruiting | ||
| Erector Spinae Plane Block in Lumbar Spinal Fusion : Double-blind, Randomized Controlled Trial.[NCT04904575] | 130 participants (Anticipated) | Interventional | 2022-01-03 | Recruiting | |||
| Erector Spinae Plane Block in Lumbar Release Surgery : Double-blind, Randomized Controlled Trial[NCT04925882] | 100 participants (Actual) | Interventional | 2022-01-03 | Completed | |||
| Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543] | 90 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| Effects of Intra-Operative Ropivaciane Epidural Injection on Post-Operative Outcomes Following Elective Lumbar Fusion[NCT03035656] | Phase 4 | 228 participants (Anticipated) | Interventional | 2019-03-01 | Not yet recruiting | ||
| The Effectiveness of IV/PO Acetaminophen in the Perioperative Period in Reducing Opiate Use After Lumbar Spine Fusion: a Prospective, Randomized Controlled Trial[NCT03104816] | Phase 4 | 28 participants (Actual) | Interventional | 2016-10-31 | Terminated (stopped due to Could not get an approval from Department Reviewer for the study continuation.) | ||
| Effect of Ultrasound Guided Bilateral Thoracolumbar Interfascial Plane (TLIP) Block on Post-operative Opioid Consumption After Lumbar Spine Surgeries. A Randomized Double Blinded Study.[NCT03193658] | 34 participants (Actual) | Interventional | 2017-08-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Determine the impact of administering a supplemental non-opioid analgesic drug such as IV/oral acetaminophen on total opioid dose administered over the perioperative period. (NCT03104816)
Timeframe: Within 24 hours after surgery
| Intervention | mg (Mean) | |
|---|---|---|
| PACU dose | Ward dose | |
| Acetaminophen IV Soln 10 MG/ML (A) | 1.2 | 9.8 |
| Hydromorphone (Control Arm) (C) | 1.7 | 13 |
| PO Acetaminophen (B) | 1.3 | 10.4 |
4 reviews available for acetaminophen and Spinal Diseases
| Article | Year |
|---|---|
Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Com | 2015 |
Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Com | 2015 |
Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Com | 2015 |
Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Com | 2015 |
Spontaneous pneumomediastinum and epidural pneumatosis in an adolescent precipitated by weight lifting: a case report and review.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anti-Inflammatory Agents | 2009 |
Recurrent anion gap metabolic acidosis in a woman with vertebral disc disease.
Topics: Acetaminophen; Acid-Base Equilibrium; Acidosis; Analgesics, Non-Narcotic; Emergency Service, Hospita | 2011 |
Perioperative pain control in pediatric patients undergoing orthopaedic surgery.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory | 2012 |
5 trials available for acetaminophen and Spinal Diseases
| Article | Year |
|---|---|
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
Comparison of the analgesic effects of paracetamol and tramadol in lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics; Drug Monitoring; Female; Humans; Lumbar Vertebrae; Male; Middle Ag | 2015 |
Acetaminophen improves analgesia but does not reduce opioid requirement after major spine surgery in children and adolescents.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid | 2012 |
Comparative study of high bio-availability glaphenine and paracetamol in cervical and lumbar arthrosis.
Topics: Acetaminophen; Arthritis; Biological Availability; Double-Blind Method; Glafenine; Humans; Movement; | 1987 |
4 other studies available for acetaminophen and Spinal Diseases
| Article | Year |
|---|---|
[CLINICAL TRIALS OF A NEW ANTIRHEUMATIC COMBINATION PREPARATION].
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Arthritis; Arthritis, Rheumatoid; | 1963 |
Association of age with analgesic use for back and joint disorders in outpatient settings.
Topics: Acetaminophen; Adult; Age Distribution; Age Factors; Aged; Ambulatory Care Facilities; Analgesics; A | 2006 |
[Benoxaprofen in the treatment of spondylosis and spondylarthrosis (author's transl)].
Topics: Acetaminophen; Adult; Benzoxazoles; Drug Evaluation; Female; Humans; Joint Diseases; Male; Middle Ag | 1981 |
[Muscle relaxants in drug therapy of orthopedic diseases].
Topics: Acetaminophen; Arthritis; Humans; Muscles; Prednisolone; Spinal Diseases; Tendinopathy | 1965 |