Page last updated: 2024-10-22

acetaminophen and Rheumatism

acetaminophen has been researched along with Rheumatism in 47 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"To determine whether multiple dosing of acetaminophen would result in drug accumulation in polymedicated elderly patients with rheumatic pain."7.71Single and multiple dose pharmacokinetics of acetaminophen (paracetamol) in polymedicated very old patients with rheumatic pain. ( Bannwarth, B; Lagrange, F; Le Bars, M; Matoga, M; Maury, S; Palisson, M; Pehourcq, F, 2001)
"Because there is controversy regarding the efficacy of acetaminophen in rheumatic diseases and because apparently safer nonsteroidal antiinflammatory drugs (NSAIDs) are being produced, we surveyed rheumatic disease patients about their preferences for these agents to determine the degree to which one type of therapeutic agent is preferred over the other."7.70Preference for nonsteroidal antiinflammatory drugs over acetaminophen by rheumatic disease patients: a survey of 1,799 patients with osteoarthritis, rheumatoid arthritis, and fibromyalgia. ( Lane, N; Wolfe, F; Zhao, S, 2000)
"The purpose of this study was to investigate the risk of transitional cell carcinoma among subjects with an intake of acetaminophen, aspirin, some other drugs and with some intercurrent diseases."7.69Acetaminophen, some other drugs, some diseases and the risk of transitional cell carcinoma. A population-based case-control study. ( Gerhardsson de Verdier, M; Steineck, G; Wiholm, BE, 1995)
"To determine whether multiple dosing of acetaminophen would result in drug accumulation in polymedicated elderly patients with rheumatic pain."3.71Single and multiple dose pharmacokinetics of acetaminophen (paracetamol) in polymedicated very old patients with rheumatic pain. ( Bannwarth, B; Lagrange, F; Le Bars, M; Matoga, M; Maury, S; Palisson, M; Pehourcq, F, 2001)
"Because there is controversy regarding the efficacy of acetaminophen in rheumatic diseases and because apparently safer nonsteroidal antiinflammatory drugs (NSAIDs) are being produced, we surveyed rheumatic disease patients about their preferences for these agents to determine the degree to which one type of therapeutic agent is preferred over the other."3.70Preference for nonsteroidal antiinflammatory drugs over acetaminophen by rheumatic disease patients: a survey of 1,799 patients with osteoarthritis, rheumatoid arthritis, and fibromyalgia. ( Lane, N; Wolfe, F; Zhao, S, 2000)
"The purpose of this study was to investigate the risk of transitional cell carcinoma among subjects with an intake of acetaminophen, aspirin, some other drugs and with some intercurrent diseases."3.69Acetaminophen, some other drugs, some diseases and the risk of transitional cell carcinoma. A population-based case-control study. ( Gerhardsson de Verdier, M; Steineck, G; Wiholm, BE, 1995)
"We tested whether this parameter and tactile allodynia, the standard pain measure in preclinical studies, show parallels in their response to analgesics and basic mechanisms."1.46Grip strength in mice with joint inflammation: A rheumatology function test sensitive to pain and analgesia. ( Cañizares, FJ; Cobos, EJ; Entrena, JM; Fernández-Segura, E; Montilla-García, Á; Perazzoli, G; Portillo-Salido, E; Tejada, MÁ, 2017)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199033 (70.21)18.7374
1990's4 (8.51)18.2507
2000's7 (14.89)29.6817
2010's3 (6.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Montilla-García, Á1
Tejada, MÁ1
Perazzoli, G1
Entrena, JM1
Portillo-Salido, E1
Fernández-Segura, E1
Cañizares, FJ1
Cobos, EJ1
Gebreselassie, A1
Aduli, F1
Howell, CD1
Wiest, J1
Schollmayer, C1
Gresser, G1
Holzgrabe, U1
ERLSBACHER, O1
COSTE, F1
PASCUCCI, F1
NOFERI, G1
SMITH, ME1
GOUGH, J1
GALPIN, OP1
KLARE, V1
DOUJAK, PH1
WIESINGER, G1
McCarberg, BH2
Dickson, DJ1
Kean, WF1
Buchanan, WW1
Nakayama, S1
Mukae, H1
Ishimatsu, Y1
Sugiyama, K1
Ide, M1
Ishimoto, H1
Hisatomi, K1
Ishii, H1
Abel, K1
Ozono, Y1
Kohno, S1
Roscioni, C1
De Ritis, G1
Lotti, A1
Pozzessere, C1
De Rossi, P1
Granato, C1
Bruno, VF1
Nola, P1
Morabito, F1
De Tommaso, G1
Owen, M1
Hills, LJ1
Steineck, G1
Wiholm, BE1
Gerhardsson de Verdier, M1
Peterson, GM1
Bergin, JK1
Nelson, BJ1
Stanton, LA1
Bannwarth, B3
Latreyte, P1
Lequen, L1
Dehais, J1
Wolfe, F1
Zhao, S1
Lane, N1
Pehourcq, F1
Lagrange, F1
Matoga, M1
Maury, S1
Palisson, M1
Le Bars, M1
Proctor, RA1
Kunin, CM1
Zampa, AM1
Roe, RL1
Müller, G1
Abadia, R1
Jammet, P1
Christoforov, B1
Cremer, GA1
Finkbeiner, G1
Auer, B1
Huskisson, EC1
Bonnamour, C1
Peaud, PY1
Plauchu, M1
Doury, P1
Perrin, LF1
Bednarík, J1
Pracke, T1
Pĕgrrímová, E1
Vykydal, M1
Jayson, MI1
Mills, JA1
Bracharz, H1
Laborie, G1
Gamarski, J1
Wettreich, W1
Fellet, AJ1
Meyer, JA1
de Châtel, A1
Risse, S1
de Mattos, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Randomized, Double-blind Study Assessing the Efficacy of Intravenous (IV) Ibuprofen Versus IV Acetaminophen for the Treatment of Pain Following Orthopaedic Low Extremity Surgery[NCT03771755]62 participants (Actual)Interventional2017-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for acetaminophen and Rheumatism

ArticleYear
Rheumatologic Diseases and the Liver.
    Clinics in liver disease, 2019, Volume: 23, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthralgia; Biological

2019
Rheumatic diseases in the elderly: dealing with rheumatic pain in extended care facilities.
    Clinics in geriatric medicine, 2005, Volume: 21, Issue:3

    Topics: Acetaminophen; Aged; Algorithms; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal;

2005
The use of NSAIDs in rheumatic disorders 2005: a global perspective.
    Inflammopharmacology, 2005, Volume: 13, Issue:4

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxyge

2005
Rheumatic diseases in the elderly: dealing with rheumatic pain in extended care facilities.
    Rheumatic diseases clinics of North America, 2007, Volume: 33, Issue:1

    Topics: Acetaminophen; Aged; Algorithms; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthri

2007
Drug therapy in rheumatic diseases.
    The Medical clinics of North America, 1977, Volume: 61, Issue:2

    Topics: Acetaminophen; Adrenal Cortex Hormones; Antimalarials; Aspirin; Colchicine; Fenoprofen; Gold; Humans

1977
[Hepatotoxicity of drugs commonly used in rheumatology].
    Annales de medecine interne, 1985, Volume: 136, Issue:7

    Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Dextrop

1985
Advances in the treatment of rheumatic diseases.
    The Practitioner, 1973, Volume: 211, Issue:264

    Topics: Acetaminophen; Alkylating Agents; Anti-Inflammatory Agents; Antimetabolites; Arthritis, Rheumatoid;

1973
Nonsteroidal anti-inflammatory drugs (first of two parts).
    The New England journal of medicine, 1974, Apr-04, Volume: 290, Issue:14

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents; Aspirin; Bone Marrow; Drug Hypersensitivity; Gastric

1974

Trials

9 trials available for acetaminophen and Rheumatism

ArticleYear
[Analgesic, antipyretic and anti-rheumatic activity of 2 preparations evaluated in a multicenter clinical trial].
    La Clinica terapeutica, 1982, Dec-15, Volume: 103, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Child; Child, Preschool; Clinical Trials

1982
How safe is dextropropoxyphene?
    The Medical journal of Australia, 1980, Jun-14, Volume: 1, Issue:12

    Topics: Acetaminophen; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind Method; Humans; Rheumatic

1980
Improving drug use in rheumatic disorders.
    Journal of clinical pharmacy and therapeutics, 1996, Volume: 21, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Family Practice; G

1996
[Treatment of acute rheumatic diseases with Probaphen in private medicine].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1976, Oct-10, Volume: 52, Issue:28

    Topics: Acetaminophen; Acute Disease; Aminopyrine; Clinical Trials as Topic; Dipyrone; Drug Combinations; Dr

1976
[Treatment of the diseases of the extended rheumatic sphere form with paracetamol (Dolo-arthrosetten)].
    Munchener medizinische Wochenschrift (1950), 1973, Oct-19, Volume: 115, Issue:42

    Topics: Acetaminophen; Anti-Inflammatory Agents; Back Pain; Cartilage Diseases; Drug Therapy, Combination; H

1973
Fenclozic acid.
    Lancet (London, England), 1970, Mar-28, Volume: 1, Issue:7648

    Topics: Acetaminophen; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspir

1970
[Experiences with Scutamil C in locomotor system disorders].
    Fysiatricky a reumatologicky vestnik, 1972, Volume: 50, Issue:6

    Topics: Acetaminophen; Carisoprodol; Clinical Trials as Topic; Drug Combinations; Female; Humans; Joint Dise

1972
An analgesic combination.
    The Practitioner, 1973, Volume: 210, Issue:256

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Drug Combinations; Family

1973
Mefenamic acid as an analgesic.
    The Practitioner, 1970, Volume: 204, Issue:224

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Drug Syn

1970

Other Studies

30 other studies available for acetaminophen and Rheumatism

ArticleYear
Grip strength in mice with joint inflammation: A rheumatology function test sensitive to pain and analgesia.
    Neuropharmacology, 2017, Volume: 125

    Topics: Acetaminophen; Analgesics; Animals; Arthritis; Celecoxib; Disease Models, Animal; Diterpenes; Female

2017
Identification and quantitation of the ingredients in a counterfeit Vietnamese herbal medicine against rheumatic diseases.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 97

    Topics: Acetaminophen; Chromatography, Liquid; Cinnamomum zeylanicum; Counterfeit Drugs; Herbal Medicine; In

2014
Notes on the therapeutic action of rubrophen in rheumatic constellation processes.
    Sugestiones, 1948, Volume: 14, Issue:157

    Topics: Acetaminophen; Humans; Rheumatic Diseases

1948
Antirheumatic therapy and devitaminizing action of drugs; effects of rubrophen on the ascorbic acid content of various parenchymes and protective action of vitamin C against the onset of tissue lesions caused by the drug.
    Rivista critica di clinica medica, 1945, Nov-30, Volume: 45, Issue:6-9

    Topics: Acetaminophen; Ascorbic Acid; Aurintricarboxylic Acid; Drug-Related Side Effects and Adverse Reactio

1945
ANALGESIC DRUGS FOR RHEUMATISM.
    British medical journal, 1963, Nov-23, Volume: 2, Issue:5368

    Topics: Accidents; Accidents, Occupational; Acetaminophen; Analgesics; Humans; Rheumatic Diseases

1963
[ON THE TREATMENT OF RHEUMATIC DISEASES WITH PREDNIFLEX. COMBINED THERAPY WITH ANTIRHEUMATIC AND MYOTONOLYTIC AGENTS].
    Munchener medizinische Wochenschrift (1950), 1963, Nov-15, Volume: 105

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antirheumatic Agents; Arthritis;

1963
[STUDIES OF THE EFFICACY OF A COMBINATION OF A MUSCLE RELAXANT, AN ANALGESIC AND OF PREDNISOLONE IN THE ILLNESS OF RHEUMATIC TYPE DISORDERS].
    Wiener medizinische Wochenschrift (1946), 1964, Jul-04, Volume: 114

    Topics: Acetaminophen; Analgesics; Drug Therapy; Geriatrics; Heartburn; Humans; Muscle Relaxants, Central; N

1964
Opioids for non-operable osteoarthritis and soft-tissue rheumatism.
    Arthritis research & therapy, 2005, Volume: 7, Issue:5

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents,

2005
[A case of rheumatoid lung complicated by SELAPINA-induced pneumonia].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2006, Volume: 44, Issue:11

    Topics: Acetaminophen; Aged; Amiodarone; Arthritis, Rheumatoid; Drug Combinations; Female; Humans; Lung Dise

2006
Acetaminophen, some other drugs, some diseases and the risk of transitional cell carcinoma. A population-based case-control study.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:6

    Topics: Acetaminophen; Age Factors; Analgesics; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Aspir

1995
Acetaminophen-codeine combinations for rheumatic disorders.
    Revue du rhumatisme (English ed.), 1997, Volume: 64, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Codeine; Drug Therapy, Combination; Humans; Narcotics; Rheu

1997
Is the WHO analgesic ladder for cancer pain management appropriate for rheumatology patients?
    Revue du rhumatisme (English ed.), 1999, Volume: 66, Issue:5

    Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Disease Management; Glucocortico

1999
Preference for nonsteroidal antiinflammatory drugs over acetaminophen by rheumatic disease patients: a survey of 1,799 patients with osteoarthritis, rheumatoid arthritis, and fibromyalgia.
    Arthritis and rheumatism, 2000, Volume: 43, Issue:2

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Fibromy

2000
Single and multiple dose pharmacokinetics of acetaminophen (paracetamol) in polymedicated very old patients with rheumatic pain.
    The Journal of rheumatology, 2001, Volume: 28, Issue:1

    Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Area Under Curve; Drug Therapy, Co

2001
Salicylate-induced enzymuria: comparison with other anti-inflammatory agents.
    The American journal of medicine, 1978, Volume: 65, Issue:6

    Topics: Acetaminophen; Acetylglucosaminidase; Adult; Anti-Inflammatory Agents; Aspirin; Gold; Hexosaminidase

1978
[Anti-rheumatic drugs in the geriatric age].
    La Clinica terapeutica, 1979, Oct-31, Volume: 91, Issue:2

    Topics: Acetaminophen; Adult; Age Factors; Aged; Aminopyrine; Anti-Inflammatory Agents; Antipyrine; Humans;

1979
[Clinical experience with a new antiphlogistic analgesic].
    Die Medizinische Welt, 1970, Apr-25, Volume: 17

    Topics: Acetaminophen; Adolescent; Adult; Back Pain; Female; Humans; Intervertebral Disc Displacement; Male;

1970
Recent drugs and the rheumatic diseases.
    Reports on rheumatic diseases, 1974, Issue:54

    Topics: Acetaminophen; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-

1974
[Clinical study of a new antalgic: Propofan].
    Lyon medical, 1972, Jan-23, Volume: 227, Issue:2

    Topics: Acetaminophen; Adult; Aged; Analgesics; Aspirin; Caffeine; Dextropropoxyphene; Female; Headache; His

1972
[A new treatment for pain in rheumatology].
    Therapeutique (La Semaine des hopitaux), 1972, Volume: 48, Issue:9

    Topics: Acetaminophen; Administration, Oral; Adult; Aged; Ascorbic Acid; Drug Combinations; Female; Humans;

1972
Benoral, Safapryn and Levius.
    Drug and therapeutics bulletin, 1972, Oct-27, Volume: 10, Issue:22

    Topics: Acetaminophen; Acetanilides; Acetates; Aspirin; Humans; Rheumatic Diseases; Salicylates

1972
[Clinical evaluation of a new analgesic. (Study of 1000 cases)].
    Therapeutique (La Semaine des hopitaux), 1972, Volume: 48, Issue:10

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Child; Evaluation Studies as Topic; Female; Huma

1972
[Oluprin--a clinical study of a new analgesic].
    Medizinische Klinik, 1970, Feb-13, Volume: 65, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Aged; Blood Proteins; Child; Evaluation Studies as Topic; Female;

1970
[A new antalgic drug in rheumatology: the D-propoxyphene-N-acetyl-p-aminophenol combination].
    Clinique (Paris, France), 1965, Volume: 60, Issue:614

    Topics: Acetaminophen; Dextropropoxyphene; Humans; Rheumatic Diseases

1965
[Clinical trial of the association of phenylbutazone and paracetamol in extra-articular rheumatism].
    Hospital (Rio de Janeiro, Brazil), 1966, Volume: 70, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Phenylbutazone; Rheumatic

1966
[The association of paracetamol and phenylbutazone in rheumatology. Preliminary report].
    Hospital (Rio de Janeiro, Brazil), 1966, Volume: 70, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Female; Fibromyalgia; Humans;

1966
[Association of a new analgesic with phenylbutazone in rheumatic diseases].
    Hospital (Rio de Janeiro, Brazil), 1966, Volume: 70, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Phenylbutazone; Rheumatic

1966
[Gradual reduction of corticosteroid medication in diseases of the rheumatic group].
    Praxis, 1968, Aug-20, Volume: 57, Issue:33

    Topics: Acetaminophen; Arthritis, Rheumatoid; Humans; Muscles; Prednisolone; Rheumatic Diseases

1968
[Therapy of muscular rheumatic pain with Oluprin].
    Hippokrates, 1969, Sep-15, Volume: 40, Issue:17

    Topics: Acetaminophen; Aminopyrine; Humans; Middle Aged; Phenylbutazone; Rheumatic Diseases

1969
[Use of paracetamol-phenylbutazone combination in rheumatic diseases of professional motorists].
    Hospital (Rio de Janeiro, Brazil), 1968, Volume: 74, Issue:2

    Topics: Acetaminophen; Adult; Automobile Driving; Humans; Middle Aged; Occupational Diseases; Phenylbutazone

1968