acetaminophen has been researched along with Primary Peritonitis in 5 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (20.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Liu, Y | 1 |
Seipel, C | 1 |
Lopez, ME | 1 |
Nuchtern, JG | 1 |
Brandt, ML | 1 |
Fallon, SC | 1 |
Manyang, PA | 1 |
Tjia, IM | 1 |
Baijal, RG | 1 |
Watcha, MF | 1 |
Si, Y | 1 |
Tsou, CL | 1 |
Croft, K | 1 |
Charo, IF | 1 |
Larsen, FS | 1 |
Clemmesen, JO | 1 |
Hansen, BA | 1 |
Doherty, NS | 1 |
Beaver, TH | 1 |
Chan, KY | 1 |
Dinerstein, RJ | 1 |
Diekema, KA | 1 |
Lesser, PB | 1 |
Vietti, MM | 1 |
Clark, WD | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Comparing Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy: A Randomized Controlled Trial[NCT03528343] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2017-09-05 | Withdrawn (stopped due to Lost research support for enrolling patients) | ||
ROPIVACAINE WITH CLONIDINE FOR PEDIATRIC RECTUS SHEATH BLOCKS- THE MAGIC COMBINATION? - A Double Blinded Prospective Study[NCT02439281] | 50 participants (Actual) | Interventional | 2015-05-31 | Terminated (stopped due to The patients were discharged on the day of the surgery.) | |||
A Randomized, Double-blinded, Placebo-controlled Study of Ketorolac Use in Pediatric Patients Undergoing Tonsillectomy[NCT03453541] | Phase 4 | 600 participants (Anticipated) | Interventional | 2017-11-21 | Recruiting | ||
The Evaluation of Pre-incisional and Post-closure Local Anesthetic vs. Normal Saline on Postoperative Pain in Pediatric Appendectomies[NCT02483689] | 100 participants (Anticipated) | Interventional | 2015-08-31 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Numeric Rating Pain Scores ( 0-10), will be obtained every 2 hours after PACU discharge up to 18 hours or until hospital discharge, whichever occurs first. The pain score of 0, means no pain, is a good outcome , and a pain score of 10 is excruciating pain, a very bad outcome. The average of these scores will be evaluated.The pain scores will not longer be documented after the numbness went away. (NCT02439281)
Timeframe: Logistic regression of the 4 th pain score assessment
Intervention | units on a scale (Median) |
---|---|
Ropivacaine Group | 2 |
Ropivacaine/ Clonidine Group | 1.5 |
The investigators hypothesize that patient postoperative anxiety scores are lower in the Ropivacaine/Clonidine group and postoperative anxiety scores decrease more in Ropivacaine /Clonidine Group, than in Ropivacaine Group. (NCT02439281)
Timeframe: 6 hours after block placement
Intervention | units on a scale (Median) |
---|---|
Ropivacaine Group | 30 |
Ropivacaine/ Clonidine Group | 29 |
The investigators expect no difference in incidence of complications (e.g. oversedation, hypotension, bradycardia episodes, etc.). (NCT02439281)
Timeframe: until study completion
Intervention | Participants (Count of Participants) |
---|---|
Ropivacaine/ Clonidine Group | 1 |
Ropivacaine Group | 1 |
The investigators hypothesize that rectus sheath injections with ropivacaine/ clonidine would result in longer duration of analgesia and decreased pain scores compared to ropivacaine alone. (NCT02439281)
Timeframe: indicated by the first request for pain medication at umbilicus site
Intervention | minutes (Median) |
---|---|
Ropivacaine/ Clonidine Group | 230 |
Ropivacaine Group | 240 |
The investigators hypothesize that rectus sheath injections with ropivacaine and clonidine result in longer duration of sensory block (paresthesia) compared to ropivacaine alone. (NCT02439281)
Timeframe: Indicated by return of normal sensation (expected average of 12 hours after block placement).
Intervention | minutes (Median) |
---|---|
Ropivacaine/ Clonidine Group | 823.5 |
Ropivacaine Group | 540 |
Total intravenous morphine equivalents mg/kg (NCT02439281)
Timeframe: 18 hours after surgery
Intervention | mg/kg (Median) |
---|---|
Ropivacaine/ Clonidine Group | 0.20 |
Ropivacaine Group | 0.22 |
The investigators hypothesize that rectus sheath injections with ropivacaine/ clonidine would result in better satisfaction with pain control. (NCT02439281)
Timeframe: Prior to hospital discharge (up to 24 hours after surgery)
Intervention | units on a scale (Median) |
---|---|
Ropivacaine/ Clonidine Group | 9 |
Ropivacaine Group | 9 |
5 other studies available for acetaminophen and Primary Peritonitis
Article | Year |
---|---|
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice.
Topics: Acetaminophen; Animals; Cell Differentiation; Cell Lineage; Cell Movement; Cell Proliferation; Hemat | 2010 |
[Hemorrhagic pancreatitis. A rare complication of paracetamol poisoning].
Topics: Acetaminophen; Drug Overdose; Fatal Outcome; Female; Hemorrhage; Humans; Middle Aged; Pancreatitis; | 1995 |
The antinociceptive activity of paracetamol in zymosan-induced peritonitis in mice: the role of prostacyclin and reactive oxygen species.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Analgesics; Animals; Dinoprostone; Epoprostenol; Free R | 1990 |
Lethal enhancement of therapeutic doses of acetaminophen by alcohol.
Topics: Acetaminophen; Autopsy; Bacterial Infections; Chemical and Drug Induced Liver Injury; Drug Synergism | 1986 |