acetaminophen has been researched along with Primary Graft Dysfunction in 3 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Primary Graft Dysfunction: A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with acetaminophen (15 μg/ml), a specific hemoprotein reductant, prevented CFH-dependent permeability in human lungs (P = 0." | 1.48 | Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury. ( Bastarache, JA; Cantu, E; Christie, JD; Crespo, MM; Dhillon, G; Diamond, JM; Hage, CA; Kawut, SM; Kuck, JL; Lama, VN; Landstreet, SR; Lederer, DJ; McDyer, J; McNeil, JB; Miller, A; Nagata, H; Orens, JB; Palmer, SM; Porteous, MK; Shah, PD; Shaver, CM; Ware, LB; Weinacker, A; Wickersham, N; Wille, KM, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shaver, CM | 2 |
| Wickersham, N | 2 |
| McNeil, JB | 2 |
| Nagata, H | 2 |
| Sills, G | 1 |
| Kuck, JL | 2 |
| Janz, DR | 1 |
| Bastarache, JA | 2 |
| Ware, LB | 2 |
| Miller, A | 1 |
| Landstreet, SR | 1 |
| Diamond, JM | 1 |
| Lederer, DJ | 1 |
| Kawut, SM | 1 |
| Palmer, SM | 1 |
| Wille, KM | 1 |
| Weinacker, A | 1 |
| Lama, VN | 1 |
| Crespo, MM | 1 |
| Orens, JB | 1 |
| Shah, PD | 1 |
| Hage, CA | 1 |
| Cantu, E | 1 |
| Porteous, MK | 1 |
| Dhillon, G | 1 |
| McDyer, J | 1 |
| Christie, JD | 1 |
| Seki, E | 1 |
| Brenner, DA | 1 |
| Karin, M | 1 |
1 review available for acetaminophen and Primary Graft Dysfunction
| Article | Year |
|---|---|
A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Biomarkers; Carcinoma, Hepatocellular; Cell Death; | 2012 |
2 other studies available for acetaminophen and Primary Graft Dysfunction
| Article | Year |
|---|---|
Cell-Free Hemoglobin-mediated Increases in Vascular Permeability. A Novel Mechanism of Primary Graft Dysfunction and a New Therapeutic Target.
Topics: Acetaminophen; Capillary Permeability; Endothelial Cells; Hemoglobins; Humans; Lung; Lung Transplant | 2017 |
Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.
Topics: Acetaminophen; Allografts; Capillary Permeability; Case-Control Studies; Cell Line; Endothelial Cell | 2018 |