acetaminophen has been researched along with Pre-Eclampsia in 15 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The first-line use of ibuprofen rather than acetaminophen for postpartum pain did not lengthen the duration of severe-range hypertension in women with preeclampsia with severe features." | 9.27 | Effect of ibuprofen vs acetaminophen on postpartum hypertension in preeclampsia with severe features: a double-masked, randomized controlled trial. ( Blue, NR; Drake-Lavelle, S; Holbrook, BD; Katukuri, VR; Leeman, L; Mozurkewich, EL; Murray-Krezan, C; Weinberg, D, 2018) |
| "To compare differences in blood pressure levels between patients with severe post-partum pre-eclampsia using ibuprofen or acetaminophen." | 9.24 | Ibuprofen versus acetaminophen as a post-partum analgesic for women with severe pre-eclampsia: randomized clinical study. ( Ortega, N; Solis, V; Vigil-De Gracia, P, 2017) |
| "Acetaminophen is commonly used during pregnancy." | 8.86 | A review of the literature on the effects of acetaminophen on pregnancy outcome. ( Ang, R; Breitmeyer, J; Royal, MA; Scialli, AR, 2010) |
| "Overall, 74% of women reported acetaminophen use during pregnancy." | 8.12 | Prenatal acetaminophen use in women with autoimmune disorders and adverse pregnancy and birth outcomes. ( Bandoli, G; Chambers, C; Killion, JA; Smith, CJF, 2022) |
| "To examine whether pregnant women who used acetaminophen, a prostaglandinG2 synthase inhibitor, had an increased risk of preeclampsia, gestational hypertension, thromboembolic complications, or abruptio placentae." | 7.76 | Use of acetaminophen during pregnancy and risk of preeclampsia, hypertensive and vascular disorders: a birth cohort study. ( Kogevinas, M; Olsen, J; Rebordosa, C; Sørensen, HT; Zelop, CM, 2010) |
| "Acetaminophen use during pregnancy has been associated with a reduced risk of stillbirth and preterm birth, but findings are based on few studies with small numbers of exposed women." | 7.75 | Use of acetaminophen during pregnancy and risk of adverse pregnancy outcomes. ( Bech, BH; Kogevinas, M; Olsen, J; Rebordosa, C; Sørensen, HT, 2009) |
| "The first-line use of ibuprofen rather than acetaminophen for postpartum pain did not lengthen the duration of severe-range hypertension in women with preeclampsia with severe features." | 5.27 | Effect of ibuprofen vs acetaminophen on postpartum hypertension in preeclampsia with severe features: a double-masked, randomized controlled trial. ( Blue, NR; Drake-Lavelle, S; Holbrook, BD; Katukuri, VR; Leeman, L; Mozurkewich, EL; Murray-Krezan, C; Weinberg, D, 2018) |
| "To compare differences in blood pressure levels between patients with severe post-partum pre-eclampsia using ibuprofen or acetaminophen." | 5.24 | Ibuprofen versus acetaminophen as a post-partum analgesic for women with severe pre-eclampsia: randomized clinical study. ( Ortega, N; Solis, V; Vigil-De Gracia, P, 2017) |
| " Evidence of association was convincing (class I) for maternal pre-pregnancy obesity (OR 1·63, 95% CI 1·49 to 1·77), childhood eczema (1·31, 1·20 to 1·44), hypertensive disorders during pregnancy (1·29, 1·22 to 1·36), pre-eclampsia (1·28, 1·21 to 1·35), and maternal acetaminophen exposure during pregnancy (RR 1·25, 95% CI 1·17 to 1·34)." | 5.05 | Environmental risk factors, protective factors, and peripheral biomarkers for ADHD: an umbrella review. ( Brunoni, AR; Carvalho, AF; Dragioti, E; Fornaro, M; Fusar-Poli, P; Grabovac, I; Hong, SH; Jacob, L; Jeong, GH; Kim, JH; Kim, JY; Koyanagi, A; Kronbichler, A; Lee, E; Lee, J; Lee, KH; Lee, S; Oh, H; Radua, J; Rais, TB; Salazar de Pablo, G; Schuch, F; Shin, JI; Smith, L; Solmi, M; Stickley, A; Stubbs, B; Thompson, T; Yang, L, 2020) |
| "Acetaminophen is commonly used during pregnancy." | 4.86 | A review of the literature on the effects of acetaminophen on pregnancy outcome. ( Ang, R; Breitmeyer, J; Royal, MA; Scialli, AR, 2010) |
| "Overall, 74% of women reported acetaminophen use during pregnancy." | 4.12 | Prenatal acetaminophen use in women with autoimmune disorders and adverse pregnancy and birth outcomes. ( Bandoli, G; Chambers, C; Killion, JA; Smith, CJF, 2022) |
| "To examine whether pregnant women who used acetaminophen, a prostaglandinG2 synthase inhibitor, had an increased risk of preeclampsia, gestational hypertension, thromboembolic complications, or abruptio placentae." | 3.76 | Use of acetaminophen during pregnancy and risk of preeclampsia, hypertensive and vascular disorders: a birth cohort study. ( Kogevinas, M; Olsen, J; Rebordosa, C; Sørensen, HT; Zelop, CM, 2010) |
| "Acetaminophen use during pregnancy has been associated with a reduced risk of stillbirth and preterm birth, but findings are based on few studies with small numbers of exposed women." | 3.75 | Use of acetaminophen during pregnancy and risk of adverse pregnancy outcomes. ( Bech, BH; Kogevinas, M; Olsen, J; Rebordosa, C; Sørensen, HT, 2009) |
| "Of 859,501 pregnancies, 8168 had migraine." | 1.62 | Polypharmacy and comorbidities during pregnancy in a cohort of women with migraine. ( Burch, RC; Hernandez-Diaz, S; Wood, ME, 2021) |
| "Women with preeclampsia had used significantly more often paracetamol during pregnancy compared to controls (cases 8." | 1.62 | Increased risk of preeclampsia after use of paracetamol during pregnancy - causal or coincidence? ( Keski-Nisula, L; Sahlman, H; von Hellens, H, 2021) |
| "Women with preeclampsia had used significantly more benzodiazepines, paracetamol, antihypertensives and acid-suppressive drugs than the women in the control group (p < 0." | 1.51 | Maternal use of drugs and preeclampsia. ( El-Nezami, H; Keski-Nisula, L; Koponen, M; Sahlman, H; Vähäkangas, K, 2019) |
| "In patients with preeclampsia the renal excretion of beta 2-microglobulin allows to differentiate between a primary preeclampsia and a preeclampsia superimposed upon chronic pyelonephritis." | 1.26 | Beta 2-microglobulin and other proteins as parameter for tubular function. ( Jaques, G; Keller, M; Mondorf, AW; Prüfer, D; Weise, M, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 5 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sahlman, H | 2 |
| Koponen, M | 1 |
| El-Nezami, H | 1 |
| Vähäkangas, K | 1 |
| Keski-Nisula, L | 2 |
| Wang, B | 1 |
| Yang, X | 1 |
| Yu, H | 1 |
| Man, X | 1 |
| Kim, JH | 1 |
| Kim, JY | 1 |
| Lee, J | 1 |
| Jeong, GH | 1 |
| Lee, E | 1 |
| Lee, S | 1 |
| Lee, KH | 1 |
| Kronbichler, A | 1 |
| Stubbs, B | 1 |
| Solmi, M | 1 |
| Koyanagi, A | 1 |
| Hong, SH | 1 |
| Dragioti, E | 1 |
| Jacob, L | 1 |
| Brunoni, AR | 1 |
| Carvalho, AF | 1 |
| Radua, J | 1 |
| Thompson, T | 1 |
| Smith, L | 1 |
| Oh, H | 1 |
| Yang, L | 1 |
| Grabovac, I | 1 |
| Schuch, F | 1 |
| Fornaro, M | 1 |
| Stickley, A | 1 |
| Rais, TB | 1 |
| Salazar de Pablo, G | 1 |
| Shin, JI | 1 |
| Fusar-Poli, P | 1 |
| Wood, ME | 1 |
| Burch, RC | 1 |
| Hernandez-Diaz, S | 1 |
| von Hellens, H | 1 |
| Killion, JA | 1 |
| Chambers, C | 1 |
| Smith, CJF | 1 |
| Bandoli, G | 1 |
| Blue, NR | 1 |
| Murray-Krezan, C | 1 |
| Drake-Lavelle, S | 1 |
| Weinberg, D | 1 |
| Holbrook, BD | 1 |
| Katukuri, VR | 1 |
| Leeman, L | 1 |
| Mozurkewich, EL | 1 |
| Hirshberg, JS | 1 |
| Cahill, AG | 1 |
| Vigil-De Gracia, P | 1 |
| Solis, V | 1 |
| Ortega, N | 1 |
| Dennis, AT | 1 |
| Mulligan, SM | 1 |
| Zelop, CM | 2 |
| Rebordosa, C | 2 |
| Kogevinas, M | 2 |
| Bech, BH | 1 |
| Sørensen, HT | 2 |
| Olsen, J | 2 |
| Scialli, AR | 1 |
| Ang, R | 1 |
| Breitmeyer, J | 1 |
| Royal, MA | 1 |
| Weise, M | 1 |
| Prüfer, D | 1 |
| Jaques, G | 1 |
| Keller, M | 1 |
| Mondorf, AW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Early Clinical Evaluation and Intervention of Developmental Behavioral Diseases Based on Multicenter Cohort Study[NCT06025890] | 2,100 participants (Anticipated) | Interventional | 2022-12-07 | Recruiting | |||
| Effect of Non-steroidal Anti-inflammatory Use on Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Open Label Trial[NCT03824119] | Phase 4 | 200 participants (Anticipated) | Interventional | 2018-12-11 | Recruiting | ||
| The Copenhagen Analgesic Study[NCT04369222] | 600 participants (Anticipated) | Observational | 2020-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for acetaminophen and Pre-Eclampsia
| Article | Year |
|---|---|
The comparison of ibuprofen versus acetaminophen for blood pressure in preeclampsia: a meta-analysis of randomized controlled studies.
Topics: Acetaminophen; Arterial Pressure; Blood Pressure; Female; Humans; Ibuprofen; Pre-Eclampsia; Pregnanc | 2022 |
Environmental risk factors, protective factors, and peripheral biomarkers for ADHD: an umbrella review.
Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Biomarkers; Female; Humans; Pre-Eclamp | 2020 |
A review of the literature on the effects of acetaminophen on pregnancy outcome.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Analgesics, Non-Narcotic; Animals; Antipyretics; Female; | 2010 |
2 trials available for acetaminophen and Pre-Eclampsia
| Article | Year |
|---|---|
Effect of ibuprofen vs acetaminophen on postpartum hypertension in preeclampsia with severe features: a double-masked, randomized controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2018 |
Ibuprofen versus acetaminophen as a post-partum analgesic for women with severe pre-eclampsia: randomized clinical study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Blood Pressure; Female; Humans; Ibuprofen; Postpartu | 2017 |
10 other studies available for acetaminophen and Pre-Eclampsia
| Article | Year |
|---|---|
Maternal use of drugs and preeclampsia.
Topics: Acetaminophen; Adult; Anti-Bacterial Agents; Antihypertensive Agents; Benzodiazepines; Case-Control | 2019 |
Polypharmacy and comorbidities during pregnancy in a cohort of women with migraine.
Topics: Acetaminophen; Analgesics, Opioid; Anticonvulsants; Antihypertensive Agents; Comorbidity; Female; Hu | 2021 |
Increased risk of preeclampsia after use of paracetamol during pregnancy - causal or coincidence?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Causality; Cohort Studies; Female; Gestational Age; Headach | 2021 |
Prenatal acetaminophen use in women with autoimmune disorders and adverse pregnancy and birth outcomes.
Topics: Acetaminophen; Autoimmune Diseases; Cohort Studies; Female; Humans; Infant, Newborn; Pain; Pre-Eclam | 2022 |
Pain relief: determining the safety of ibuprofen with postpartum preeclampsia.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Hypertension; Ibuprofe | 2018 |
Analgesic requirements and pain experience after caesarean section under neuraxial anesthesia in women with preeclampsia.
Topics: Acetaminophen; Adult; Analgesics; Cesarean Section; Female; Humans; Isoxazoles; Oxycodone; Pain Meas | 2016 |
Is it time to re-evaluate our use of acetaminophen in certain sub-groups of pregnant women?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Contraindications; Epoprostenol; Female; Humans; Pre-Eclamp | 2008 |
Use of acetaminophen during pregnancy and risk of adverse pregnancy outcomes.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cohort Studies; Denmark; Female; Humans; Infant; Inf | 2009 |
Use of acetaminophen during pregnancy and risk of preeclampsia, hypertensive and vascular disorders: a birth cohort study.
Topics: Acetaminophen; Adult; Algorithms; Analgesics, Non-Narcotic; Cohort Studies; Denmark; Female; Humans; | 2010 |
Beta 2-microglobulin and other proteins as parameter for tubular function.
Topics: Acetaminophen; Amino Acid Sequence; Aspirin; beta 2-Microglobulin; Beta-Globulins; Female; Graft Rej | 1981 |