Page last updated: 2024-10-22

acetaminophen and Pharyngitis

acetaminophen has been researched along with Pharyngitis in 29 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Pharyngitis: Inflammation of the throat (PHARYNX).

Research Excerpts

ExcerptRelevanceReference
" The eligible population (n = 200) with confirmed pharyngitis diagnosis on the Tonsillo Pharyngitis Assessment and moderate to severe sore throat was randomly divided into two cohorts to be administered with 50 mg of dexketoprofen (n = 98) or 1000-mg paracetamol (n = 102)."9.41Comparative evaluation of intravenous dexketoprofen and paracetamol in the management of pain induced by sore throat. ( Cimen, U; Cimen, YK; Erdur, B; Oncel, G; Ozen, M; Seyit, M; Turkcuer, I; Yilmaz, A, 2021)
"A single oral dose of paracetamol or ketoprofen lysine salt are safe and effective analgesic treatments for children with sore throat in daily pediatric ambulatory care."9.15A randomized, double-blind, placebo-controlled trial of paracetamol and ketoprofren lysine salt for pain control in children with pharyngotonsillitis cared by family pediatricians. ( Carozzino, L; Del Vecchio, A; Della Casa Alberighi, O; Dionisio, P; Freschi, F; Jamone, R; Martini, A; Picollo, G; Ruperto, N; Salvatori, E; Zera, M, 2011)
"The aim of this study was to determine the time to onset of pain relief from a single dose of a tablet formulation of paracetamol (acetaminophen) containing sodium bicarbonate (PSC)."9.12Onset of analgesia of a paracetamol tablet containing sodium bicarbonate: A double-blind, placebo-controlled study in adult patients with acute sore throat. ( Bey, M; Burnett, I; Grattan, T; Littlejohn, S; Sanner, K; Schachtel, B, 2006)
"To compare efficacy and safety of strepfen (flurbiprofen) to those of oral paracetamol in acute infections of the upper respiratory tracts for relief of throat pain (TP)."9.11[Results of an open prospective controlled randomized comparative trial of flurbiprofen and paracetamol efficacy and tolerance in patients with throat pain]. ( Balandin, AV; Dimova, AD; Sedinkin, AA, 2005)
"2 g daily), aspirin and paracetamol (both up to 3 g daily) for up to seven days, in patients with mild to moderate pain resulting from cold/flu symptoms or sore throat (CF/ST) (n = 2,815)."9.10Tolerability of ibuprofen, aspirin and paracetamol for the treatment of cold and flu symptoms and sore throat pain. ( Cairns, R; Le Parc, JM; Moore, N; Schneid, H; van Ganse, E; Wall, R, 2002)
"Sore throat pain provided a sensitive model to assess the analgesic efficacy of class I analgesics and discriminated between the analgesic efficacy of ibuprofen and paracetamol."9.09Use of a simple pain model to evaluate analgesic activity of ibuprofen versus paracetamol. ( Bhagat, K; Lala, I; Leech, P; Montgomery, L, 2000)
" The eligible population (n = 200) with confirmed pharyngitis diagnosis on the Tonsillo Pharyngitis Assessment and moderate to severe sore throat was randomly divided into two cohorts to be administered with 50 mg of dexketoprofen (n = 98) or 1000-mg paracetamol (n = 102)."5.41Comparative evaluation of intravenous dexketoprofen and paracetamol in the management of pain induced by sore throat. ( Cimen, U; Cimen, YK; Erdur, B; Oncel, G; Ozen, M; Seyit, M; Turkcuer, I; Yilmaz, A, 2021)
"A single oral dose of paracetamol or ketoprofen lysine salt are safe and effective analgesic treatments for children with sore throat in daily pediatric ambulatory care."5.15A randomized, double-blind, placebo-controlled trial of paracetamol and ketoprofren lysine salt for pain control in children with pharyngotonsillitis cared by family pediatricians. ( Carozzino, L; Del Vecchio, A; Della Casa Alberighi, O; Dionisio, P; Freschi, F; Jamone, R; Martini, A; Picollo, G; Ruperto, N; Salvatori, E; Zera, M, 2011)
"The aim of this study was to determine the time to onset of pain relief from a single dose of a tablet formulation of paracetamol (acetaminophen) containing sodium bicarbonate (PSC)."5.12Onset of analgesia of a paracetamol tablet containing sodium bicarbonate: A double-blind, placebo-controlled study in adult patients with acute sore throat. ( Bey, M; Burnett, I; Grattan, T; Littlejohn, S; Sanner, K; Schachtel, B, 2006)
"To compare efficacy and safety of strepfen (flurbiprofen) to those of oral paracetamol in acute infections of the upper respiratory tracts for relief of throat pain (TP)."5.11[Results of an open prospective controlled randomized comparative trial of flurbiprofen and paracetamol efficacy and tolerance in patients with throat pain]. ( Balandin, AV; Dimova, AD; Sedinkin, AA, 2005)
"2 g daily), aspirin and paracetamol (both up to 3 g daily) for up to seven days, in patients with mild to moderate pain resulting from cold/flu symptoms or sore throat (CF/ST) (n = 2,815)."5.10Tolerability of ibuprofen, aspirin and paracetamol for the treatment of cold and flu symptoms and sore throat pain. ( Cairns, R; Le Parc, JM; Moore, N; Schneid, H; van Ganse, E; Wall, R, 2002)
"Sore throat pain provided a sensitive model to assess the analgesic efficacy of class I analgesics and discriminated between the analgesic efficacy of ibuprofen and paracetamol."5.09Use of a simple pain model to evaluate analgesic activity of ibuprofen versus paracetamol. ( Bhagat, K; Lala, I; Leech, P; Montgomery, L, 2000)
"To assess the sore throat pain model in children as an assay for systemic analgesic agents in children under double-blind, placebo-controlled conditions, we conducted a single-dose parallel study that compared 10 mg/kg ibuprofen (n = 39), a new analgesic agent for children, and 15 mg/kg acetaminophen (n = 38), an approved analgesic for children, to placebo (n = 39) in children from 2 to 12 years of age with acute sore throat."5.07A placebo-controlled model for assaying systemic analgesics in children. ( Schachtel, BP; Thoden, WR, 1993)
" Patients with tonsillopharyngitis randomly received either 400 mg ibuprofen (n = 39), 1000 mg acetaminophen (n = 40), or placebo (n = 41)."5.06Sore throat pain in the evaluation of mild analgesics. ( Baybutt, RI; Fillingim, JM; Lane, AC; Schachtel, BP; Thoden, WR, 1988)
"In practice, flurbiprofen lozenges have a negative risk-benefit balance in the treatment of sore throat; it is better to suck real sweets and, if necessary, take oral paracetamol."3.74Flurbiprofen: new indication. Lozenges: NSAIDs are not to be taken like sweets! ( , 2007)
"POST, hoarseness, and dysphagia were monitored."2.84Combined intraoperative paracetamol and preoperative dexamethasone reduces postoperative sore throat: a prospective randomized study. ( Jeong, MH; Kim, HC; Lee, J; Park, HP, 2017)
" There were no adverse reactions in either group."2.68[Comparative, randomized, parallel clinical study of the effectiveness and safety of aceclofenac vs. paracetamol in the treatment of viral pharyngoamygdalitis]. ( Conti, M, 1997)
"In patients with high likelihood of streptococcal infections (e."1.38Guideline for the management of acute sore throat. ( Esposito, S; Galeone, C; Grigoryan, L; Huovinen, P; Little, P; Pelucchi, C; Verheij, T, 2012)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.34)18.7374
1990's4 (13.79)18.2507
2000's10 (34.48)29.6817
2010's10 (34.48)24.3611
2020's2 (6.90)2.80

Authors

AuthorsStudies
Yagi, S1
Endo, I1
Murakami, T1
Hida, T1
Yamamoto, Y1
Soga, T1
Ise, T1
Kusunose, K1
Yamaguchi, K1
Fukuda, D1
Yamada, H1
Soeki, T1
Wakatsuki, T1
Kawahito, S1
Sata, M1
De Vocht, K1
Debie, T1
Bastiaens, H1
Anthierens, S1
Cimen, U1
Yilmaz, A1
Cimen, YK1
Seyit, M1
Ozen, M1
Erdur, B1
Turkcuer, I1
Oncel, G1
Lee, J1
Park, HP1
Jeong, MH1
Kim, HC1
Kenealy, T4
Voelker, M1
Schachtel, BP3
Cooper, SA1
Gatoulis, SC1
Frye, R1
Bailey, J1
Blevins, AE1
Ruperto, N1
Carozzino, L1
Jamone, R1
Freschi, F1
Picollo, G1
Zera, M1
Della Casa Alberighi, O1
Salvatori, E1
Del Vecchio, A1
Dionisio, P1
Martini, A1
Pelucchi, C1
Grigoryan, L1
Galeone, C1
Esposito, S1
Huovinen, P1
Little, P1
Verheij, T1
Takeo, N1
Hatano, Y1
Yamamoto, K1
Shiota, S1
Fujiwara, S1
Moore, N1
Le Parc, JM1
van Ganse, E1
Wall, R1
Schneid, H1
Cairns, R1
Lala, I1
Leech, P1
Montgomery, L1
Bhagat, K1
FICHSEL, H1
Del Mar, C2
Glasziou, P2
Sedinkin, AA1
Balandin, AV1
Dimova, AD1
Rallis, E1
Balatsouras, DG1
Kouskoukis, C1
Verros, C1
Homsioglou, E1
Burnett, I1
Schachtel, B1
Sanner, K1
Bey, M1
Grattan, T1
Littlejohn, S1
Thoden, WR2
Conti, M1
Thomas, M1
Thamlikitkul, V1
Dechatiwongse, T1
Theerapong, S1
Chantrakul, C1
Boonroj, P1
Punkrut, W1
Ekpalakorn, W1
Boontaeng, N1
Taechaiya, S1
Petcharoen, S1
Bertin, L1
Pons, G1
d'Athis, P1
Lasfargues, G1
Maudelonde, C1
Duhamel, JF1
Olive, G1
Middleton, DB1
D'Amico, F1
Merenstein, JH1
Fillingim, JM1
Lane, AC1
Baybutt, RI1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Onset of Action of a Fast Release Aspirin Tablet and Acetaminophen Caplet in Sore Throat Pain[NCT01453400]Phase 3177 participants (Actual)Interventional2011-09-27Completed
Comparative Onset of Action of a Fast Release Aspirin Tablet in a Dental Impaction Pain Model[NCT01420094]Phase 3510 participants (Actual)Interventional2011-06-16Completed
Randomized, Comparative, Double Blind Controlled Phase II Clinical Trial, to Evaluate the Efficacy of ApE in Patients With Multiple Sclerosis (MS).[NCT02280876]Phase 1/Phase 230 participants (Actual)Interventional2012-01-31Completed
Inhaled Glucocorticoids for Acute Pharyngitis: A Randomized Clinical Trial[NCT04027322]Phase 2/Phase 3200 participants (Actual)Interventional2019-06-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for acetaminophen and Pharyngitis

ArticleYear
Sore throat.
    BMJ clinical evidence, 2014, Mar-04, Volume: 2014

    Topics: Acetaminophen; Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroid

2014
Sore throat.
    BMJ clinical evidence, 2007, Nov-20, Volume: 2007

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Humans;

2007
Sore throat.
    BMJ clinical evidence, 2011, Jan-13, Volume: 2011

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adrenal Cortex Hormones; Anti-Bacterial Agents;

2011
Clinical inquiries. Which treatments provide the most relief for pharyngitis pain?
    The Journal of family practice, 2011, Volume: 60, Issue:5

    Topics: Acetaminophen; Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Evidenc

2011
Sore throat.
    Clinical evidence, 2004, Issue:12

    Topics: Acetaminophen; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Humans; Pharyngitis

2004
How effective are treatments other than antibiotics for acute sore throat?
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2000, Volume: 50, Issue:459

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic;

2000

Trials

14 trials available for acetaminophen and Pharyngitis

ArticleYear
Comparative evaluation of intravenous dexketoprofen and paracetamol in the management of pain induced by sore throat.
    International journal of clinical practice, 2021, Volume: 75, Issue:10

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ketoprofen; Pai

2021
Combined intraoperative paracetamol and preoperative dexamethasone reduces postoperative sore throat: a prospective randomized study.
    Journal of anesthesia, 2017, Volume: 31, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Dexamethasone; Doubl

2017
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
A randomized, double-blind, placebo-controlled trial of paracetamol and ketoprofren lysine salt for pain control in children with pharyngotonsillitis cared by family pediatricians.
    Italian journal of pediatrics, 2011, Sep-29, Volume: 37

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Ambulatory Care; Analgesics, Non-Narcotic; Anti-

2011
Tolerability of ibuprofen, aspirin and paracetamol for the treatment of cold and flu symptoms and sore throat pain.
    International journal of clinical practice, 2002, Volume: 56, Issue:10

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Co

2002
Use of a simple pain model to evaluate analgesic activity of ibuprofen versus paracetamol.
    East African medical journal, 2000, Volume: 77, Issue:9

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Male

2000
[Results of an open prospective controlled randomized comparative trial of flurbiprofen and paracetamol efficacy and tolerance in patients with throat pain].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Female; Flurbiprofen; Humans; Male

2005
Onset of analgesia of a paracetamol tablet containing sodium bicarbonate: A double-blind, placebo-controlled study in adult patients with acute sore throat.
    Clinical therapeutics, 2006, Volume: 28, Issue:9

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adult; Analgesia; Analgesics, Non-Narcotic; Doub

2006
A placebo-controlled model for assaying systemic analgesics in children.
    Clinical pharmacology and therapeutics, 1993, Volume: 53, Issue:5

    Topics: Acetaminophen; Child; Child, Preschool; Double-Blind Method; Female; Humans; Ibuprofen; Male; Pain;

1993
[Comparative, randomized, parallel clinical study of the effectiveness and safety of aceclofenac vs. paracetamol in the treatment of viral pharyngoamygdalitis].
    Acta otorrinolaringologica espanola, 1997, Volume: 48, Issue:2

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Male; Mid

1997
Efficacy of Andrographis paniculata, Nees for pharyngotonsillitis in adults.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1991, Volume: 74, Issue:10

    Topics: Acetaminophen; Adolescent; Adult; Child; Double-Blind Method; Female; Humans; Male; Pharyngitis; Pla

1991
Randomized, double-blind, multicenter, controlled trial of ibuprofen versus acetaminophen (paracetamol) and placebo for treatment of symptoms of tonsillitis and pharyngitis in children.
    The Journal of pediatrics, 1991, Volume: 119, Issue:5

    Topics: Acetaminophen; Administration, Oral; Child; Deglutition; Double-Blind Method; Drug Tolerance; Female

1991
Standardized symptomatic treatment versus penicillin as initial therapy for streptococcal pharyngitis.
    The Journal of pediatrics, 1988, Volume: 113, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Aspirin; Child; Child, Preschool; Clinical Trials as Topic; Humans

1988
Sore throat pain in the evaluation of mild analgesics.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:6

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics; Double-Blind Method; Drug Evaluation; Fem

1988

Other Studies

9 other studies available for acetaminophen and Pharyngitis

ArticleYear
Adult onset of Immunoglobulin A vasculitis - A case report.
    The journal of medical investigation : JMI, 2019, Volume: 66, Issue:3.4

    Topics: Acetaminophen; Adult; Factor XIII; Humans; IgA Vasculitis; Immunoglobulin A; Male; Pharyngitis; Prot

2019
The use of paracetamol for first-line treatment of acute sore throat. A descriptive generic qualitative study of GPs and patients.
    The European journal of general practice, 2021, Volume: 27, Issue:1

    Topics: Acetaminophen; Adult; Anti-Bacterial Agents; General Practitioners; Guideline Adherence; Humans; Pha

2021
Sore throat.
    American family physician, 2015, May-15, Volume: 91, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroi

2015
Best drugs for what ails you: the brands to buy--and those to skip.
    Consumer reports, 2009, Volume: 74, Issue:9

    Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorpha

2009
Guideline for the management of acute sore throat.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2012, Volume: 18 Suppl 1

    Topics: Acetaminophen; Anti-Bacterial Agents; Chlamydophila Infections; Chlamydophila pneumoniae; Disease Ma

2012
Case of Mycoplasma pneumoniae infection with maculopapular-type eruptions due to acetaminophen.
    The Journal of dermatology, 2013, Volume: 40, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Asian People; Drug Eruptions;

2013
[EXPERIENCES WITH A NEW ANTIPYRETIC AND ANALGESIC IN A NEW RECTAL CAPSULE FORM].
    Kinderarztliche Praxis, 1963, Volume: 31

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Bronchitis; Bronchopneumonia; Cap

1963
Drug eruptions in children with ENT infections.
    International journal of pediatric otorhinolaryngology, 2006, Volume: 70, Issue:1

    Topics: Acetaminophen; Adolescent; Amoxicillin-Potassium Clavulanate Combination; Cephalosporins; Child; Chi

2006
Flurbiprofen: new indication. Lozenges: NSAIDs are not to be taken like sweets!
    Prescrire international, 2007, Volume: 16, Issue:87

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Can

2007