Page last updated: 2024-10-22

acetaminophen and Periapical Diseases

acetaminophen has been researched along with Periapical Diseases in 5 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Periapical Diseases: Diseases of the PERIAPICAL TISSUE surrounding the root of the tooth, which is distinguished from DENTAL PULP DISEASES inside the TOOTH ROOT.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wells, LK1
Drum, M1
Nusstein, J1
Reader, A5
Beck, M5
Nusstein, JM1
Nist, E1
Pickenpaugh, L1
Meyers, WJ1
Peterson, LJ1
Henry, M1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect on Initial Endodontic Treatment on Postoperative Pain in Symptomatic Teeth With Pulpal Necrosis[NCT01870973]108 participants (Actual)Interventional2013-03-31Completed
Effect of Preoperative, Single-dose Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain in Patients With Symptomatic Apical Periodontitis: A Double-Blind Randomized Controlled Trial.[NCT03033147]72 participants (Actual)Interventional2019-10-18Completed
Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain in Patients With Symptomatic Apical Periodontitis: A Randomized Controlled Trial[NCT03007342]78 participants (Anticipated)Interventional2017-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Percent of Patients With Success as Defined by no or Mild Pain as Analyzed on a VAS Scale and no Narcotic Use

"pain measurement as assessed on a visual analog scale and pain medication usage~definition of success = no or mild pain as analyzed on VAS scale and no narcotic use; analyzed by logistic regression~VAS scale is 0 to 170 mm with the higher numbers indicating more pain and less success." (NCT01870973)
Timeframe: each day for 5 days

Interventionpercentage of participants (Number)
Root Canal Treatment52
no Root Canal Treatment43

Trials

4 trials available for acetaminophen and Periapical Diseases

ArticleYear
Efficacy of Ibuprofen and ibuprofen/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis.
    Journal of endodontics, 2011, Volume: 37, Issue:12

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St

2011
Effect of apical trephination on postoperative pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anti-Infla

2001
Effect of prophylactic amoxicillin on endodontic flare-up in asymptomatic, necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:1

    Topics: Acetaminophen; Adult; Amoxicillin; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Varianc

2001
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla

2001
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla

2001
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla

2001
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla

2001

Other Studies

1 other study available for acetaminophen and Periapical Diseases

ArticleYear
Effect of drainage upon access on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2002, Volume: 28, Issue:8

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St

2002