Page last updated: 2024-10-22

acetaminophen and Pancreatitis

acetaminophen has been researched along with Pancreatitis in 33 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to assess whether acetaminophen poisoning is associated with a higher risk of acute pancreatitis."7.81Acetaminophen Poisoning and Risk of Acute Pancreatitis: A Population-Based Cohort Study. ( Chen, SJ; Hsu, CW; Kao, CH; Lin, CL; Lin, CS, 2015)
"Here we present the case of a young female with a delayed onset acetaminophen-induced pancreatitis."7.80Acetaminophen-induced pancreatic pseudocyst: first case report. ( Cavanaugh, Z; Naut, ER, 2014)
"We report the case of a 35-year-old woman who presented with acute pancreatitis and severe metabolic acidosis after overdosing on a drug containing acetaminophen."7.75Acetaminophen-induced acute pancreatitis. A case report. ( Igarashi, H; Ito, T; Oono, T; Sakai, H; Takayanagi, R; Yoshinaga, M, 2009)
" Although her consciousness and hemodynamic status gradually improved after treatment with N-acetylcysteine and other supportive measures, she was found to have pancytopenia, pancreatitis and hepatorenal failure during the hospitalization and eventually died 18 d post-admission."7.71Pancytopenia, hyperglycemia, shock, coma, rhabdomyolysis, and pancreatitis associated with acetaminophen poisoning. ( Deng, JF; Lin, TJ; Yang, CC, 2001)
"This is the fourth reported case of acute pancreatitis associated with acetaminophen overdose."7.68Acetaminophen induced pancreatitis. ( Caraccio, TR; Mofenson, HC; Nawaz, H; Steckler, G, 1991)
"In this study, the analgesic effectiveness of tramadol, a synthetic opioid, was compared with paracetamol and dexketoprofen in adult patients with acute pancreatitis in the emergency department."5.22Pain treatment in patients with acute pancreatitis: A randomized controlled trial. ( Dur, A; Gülen, B; Karcıoğlu, Ö; Serinken, M; Sönmez, E, 2016)
" We analyzed gastric emptying and hormonal adaptation of cholecystokinin (CCK), pancreatic polypeptide (PP), and gastrin following two surgical procedures for chronic pancreatitis (CP): the PPW and the duodenum-preserving pancreatic head resection (DPPHR)."5.08Gastric emptying following pylorus-preserving Whipple and duodenum-preserving pancreatic head resection in patients with chronic pancreatitis. ( Beger, HG; Büchler, MW; Friess, H; Glasbrenner, B; Kleeff, J; Lauterburg, B; Müller, MW; Riepl, RL, 1997)
" Less convincing, but suggestive evidence exists for: 1-asparaginase, iatrogenic hypercalcemia, chlorthalidine, corticosteroids, ethacrynic acid, phenformin, and procainamide."4.76Drug-induced pancreatitis: a critical review. ( Kern, F; Mallory, A, 1980)
"The aim of this study was to assess whether acetaminophen poisoning is associated with a higher risk of acute pancreatitis."3.81Acetaminophen Poisoning and Risk of Acute Pancreatitis: A Population-Based Cohort Study. ( Chen, SJ; Hsu, CW; Kao, CH; Lin, CL; Lin, CS, 2015)
"Here we present the case of a young female with a delayed onset acetaminophen-induced pancreatitis."3.80Acetaminophen-induced pancreatic pseudocyst: first case report. ( Cavanaugh, Z; Naut, ER, 2014)
"We report the case of a 35-year-old woman who presented with acute pancreatitis and severe metabolic acidosis after overdosing on a drug containing acetaminophen."3.75Acetaminophen-induced acute pancreatitis. A case report. ( Igarashi, H; Ito, T; Oono, T; Sakai, H; Takayanagi, R; Yoshinaga, M, 2009)
" Although her consciousness and hemodynamic status gradually improved after treatment with N-acetylcysteine and other supportive measures, she was found to have pancytopenia, pancreatitis and hepatorenal failure during the hospitalization and eventually died 18 d post-admission."3.71Pancytopenia, hyperglycemia, shock, coma, rhabdomyolysis, and pancreatitis associated with acetaminophen poisoning. ( Deng, JF; Lin, TJ; Yang, CC, 2001)
"This is the fourth reported case of acute pancreatitis associated with acetaminophen overdose."3.68Acetaminophen induced pancreatitis. ( Caraccio, TR; Mofenson, HC; Nawaz, H; Steckler, G, 1991)
"Severe intoxication from excessive acetaminophen without suicidal intent occurred in three patients, all alcohol abusers, one with evidence of underlying cirrhosis."3.67Enhanced toxicity of acetaminophen in alcoholics: report of three cases. ( Gluskin, LE; Leist, MH; Payne, JA, 1985)
"Pain is the most common symptom of acute pancreatitis (AP), and opioids have been utilized as the cornerstone of treatment."1.91Analgesic Patterns and Opioid Administration in Children Hospitalized With Acute Pancreatitis. ( Abu-El-Haija, M; Gorbounova, I; Palermo, TM; Tham, SW, 2023)
"Patients enrolled in the Acute Liver Failure Study Group registry with an admission amylase value available were included."1.35The role of etiology in the hyperamylasemia of acute liver failure. ( Blei, AT; Coté, GA; Daud, A; Gottstein, JH, 2009)
"Hyperamylasaemia and even acute pancreatitis have been reported in patients with paracetamol poisoning."1.32Hyperamylasaemia and acute pancreatitis in paracetamol poisoning. ( Dalhoff, K; Schmidt, LE, 2004)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19907 (21.21)18.7374
1990's9 (27.27)18.2507
2000's10 (30.30)29.6817
2010's5 (15.15)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Gorbounova, I1
Tham, SW1
Abu-El-Haija, M1
Palermo, TM1
Currie, CJ1
Hoque, R1
Farooq, A1
Malik, A1
Trawick, BN1
Berberich, DW1
McClurg, JP1
Galen, KP1
Mehal, W1
Cavanaugh, Z1
Naut, ER1
Chen, SJ1
Lin, CS1
Hsu, CW1
Lin, CL1
Kao, CH1
Gülen, B2
Dur, A2
Serinken, M2
Karcıoğlu, Ö2
Sönmez, E1
Kocyigit, A1
Eken, C1
Kilic, E1
Coté, GA1
Gottstein, JH1
Daud, A1
Blei, AT1
Igarashi, H1
Ito, T1
Yoshinaga, M1
Oono, T1
Sakai, H1
Takayanagi, R1
Locher, C1
Lambare, B1
Fischer, D1
Labayle, D1
Kubuschok, B1
Xie, X1
Jesnowski, R1
Preuss, KD1
Romeike, BF1
Neumann, F1
Regitz, E1
Pistorius, G1
Schilling, M1
Scheunemann, P1
Izbicki, JR1
Löhr, JM1
Pfreundschuh, M1
Schmidt, LE1
Dalhoff, K1
Casassus-Builhé, D1
Rey, P1
Carrére, C1
Belhassen García, M1
Geijo Martínez, F1
Carpio Pérez, A1
Sánchez Martín, F1
Prieto Vicente, V1
Prescott, LF2
Erickson, RA1
Runyon, BA1
Mallory, A1
Kern, F1
Larsen, FS1
Clemmesen, JO1
Hansen, BA1
Hastier, P1
Demarquay, JF1
Maes, B1
Caroli-Bosc, FX1
Dumas, R1
Delmont, J1
Chichmanian, RM1
Jones, AL1
Müller, MW1
Friess, H1
Beger, HG1
Kleeff, J1
Lauterburg, B1
Glasbrenner, B1
Riepl, RL1
Büchler, MW1
Farrell, J1
Schmitz, PG1
Leach, FN1
Braganza, JM1
Renkes, P1
Tréchot, P1
Yang, CC1
Deng, JF1
Lin, TJ1
Kovalev, Y1
Lurie, M1
Naschitz, JE1
Yeshurun, D1
Zuckerman, E1
Lederman, JC1
Nawaz, H2
Gilmore, IT1
Tourvas, E1
Coward, RA1
Mofenson, HC1
Caraccio, TR1
Steckler, G1
Chevalier, X1
Awada, H1
Baetz, A1
Amor, B1
Caldarola, V1
Hassett, JM1
Hall, AH1
Bronstein, AB1
Kulig, KW1
Rumack, BH1
Leist, MH1
Gluskin, LE1
Payne, JA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multi-Center Trial to Study Acute Liver Failure in Adults[NCT00518440]3,488 participants (Actual)Observational1998-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for acetaminophen and Pancreatitis

ArticleYear
Paracetamol overdosage. Pharmacological considerations and clinical management.
    Drugs, 1983, Volume: 25, Issue:3

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Drug Interactions; Glutathione; Hear

1983
Drug-induced pancreatitis: a critical review.
    Gastroenterology, 1980, Volume: 78, Issue:4

    Topics: Acetaminophen; Adrenal Cortex Hormones; Amphetamines; Asparaginase; Azathioprine; Chlorthalidone; Ch

1980
Unusual complications of paracetamol poisoning.
    QJM : monthly journal of the Association of Physicians, 1997, Volume: 90, Issue:3

    Topics: Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Animals; Esophageal and Gastric Varice

1997
Metastatic small cell carcinoma presenting as acute hepatic failure.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Di

2001
Toxic interaction of didanosine and acetaminophen leading to severe hepatitis and pancreatitis: a case report and review of the literature.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Di

2001

Trials

3 trials available for acetaminophen and Pancreatitis

ArticleYear
Pain treatment in patients with acute pancreatitis: A randomized controlled trial.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2016, Volume: 27, Issue:2

    Topics: Abdominal Pain; Acetaminophen; Acute Disease; Administration, Intravenous; Adult; Aged; Analgesics,

2016
Oxidative Status and DNA Damage Following Analgesic Treatment in Patients with Acute Pancreatitis.
    Clinical laboratory, 2016, Jul-01, Volume: 62, Issue:7

    Topics: Acetaminophen; Acute Disease; Analgesics; Antioxidants; DNA Damage; Female; Humans; Ketoprofen; Leuk

2016
Gastric emptying following pylorus-preserving Whipple and duodenum-preserving pancreatic head resection in patients with chronic pancreatitis.
    American journal of surgery, 1997, Volume: 173, Issue:4

    Topics: Acetaminophen; Adult; Cholecystokinin; Chronic Disease; Female; Gastric Emptying; Gastrins; Humans;

1997

Other Studies

25 other studies available for acetaminophen and Pancreatitis

ArticleYear
Analgesic Patterns and Opioid Administration in Children Hospitalized With Acute Pancreatitis.
    Journal of pediatric gastroenterology and nutrition, 2023, 06-01, Volume: 76, Issue:6

    Topics: Acetaminophen; Acute Disease; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroida

2023
Scientific independence and objectivity: many questions linger about treatment of type 2 diabetes, such as scientific study design, optimal glucose control and the safety of injecting exogenous insulin.
    Postgraduate medicine, 2020, Volume: 132, Issue:8

    Topics: Acetaminophen; Blood Glucose; Clinical Decision-Making; Diabetes Mellitus, Type 2; Endpoint Determin

2020
A novel small-molecule enantiomeric analogue of traditional (-)-morphinans has specific TLR9 antagonist properties and reduces sterile inflammation-induced organ damage.
    Journal of immunology (Baltimore, Md. : 1950), 2013, Apr-15, Volume: 190, Issue:8

    Topics: Acetaminophen; Animals; Clinical Trials, Phase I as Topic; HEK293 Cells; Humans; Inflammation Mediat

2013
Acetaminophen-induced pancreatic pseudocyst: first case report.
    Connecticut medicine, 2014, Volume: 78, Issue:1

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Female; Humans; Liver Function Tests;

2014
Acetaminophen Poisoning and Risk of Acute Pancreatitis: A Population-Based Cohort Study.
    Medicine, 2015, Volume: 94, Issue:29

    Topics: Acetaminophen; Adult; Age Factors; Analgesics, Non-Narcotic; Comorbidity; Female; Humans; Incidence;

2015
The role of etiology in the hyperamylasemia of acute liver failure.
    The American journal of gastroenterology, 2009, Volume: 104, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Female; Humans; Hyperamylasemia; Liver Failure, Acut

2009
Acetaminophen-induced acute pancreatitis. A case report.
    JOP : Journal of the pancreas, 2009, Sep-04, Volume: 10, Issue:5

    Topics: Acetaminophen; Acidosis; Adult; Drug Overdose; Female; Humans; Pancreatitis

2009
[Acute pancreatitis induced by codeine-acetaminophen association: report of two cases].
    Gastroenterologie clinique et biologique, 2003, Volume: 27, Issue:1

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Em

2003
Expression of cancer testis antigens in pancreatic carcinoma cell lines, pancreatic adenocarcinoma and chronic pancreatitis.
    International journal of cancer, 2004, Apr-20, Volume: 109, Issue:4

    Topics: Acetaminophen; Adenocarcinoma; Antigens, Neoplasm; Chronic Disease; DNA-Binding Proteins; Female; Ge

2004
Hyperamylasaemia and acute pancreatitis in paracetamol poisoning.
    Alimentary pharmacology & therapeutics, 2004, Jul-15, Volume: 20, Issue:2

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic;

2004
[Association of paracetamol and codeine, a rare cause of acute drug-induced pancreatitis].
    Presse medicale (Paris, France : 1983), 2004, Apr-24, Volume: 33, Issue:8

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Antitussive Agents; Codeine; Humans;

2004
[Pancreatitis due to acetaminophen-codeine].
    Anales de medicina interna (Madrid, Spain : 1984), 2006, Volume: 23, Issue:8

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Antitussive Agents; Codeine; Humans; Male; M

2006
Acetaminophen hepatotoxicity associated with alcoholic pancreatitis.
    Archives of internal medicine, 1984, Volume: 144, Issue:7

    Topics: Acetaminophen; Alcoholism; Chemical and Drug Induced Liver Injury; Humans; Pancreatitis; Substance-R

1984
[Hemorrhagic pancreatitis. A rare complication of paracetamol poisoning].
    Ugeskrift for laeger, 1995, Feb-13, Volume: 157, Issue:7

    Topics: Acetaminophen; Drug Overdose; Fatal Outcome; Female; Hemorrhage; Humans; Middle Aged; Pancreatitis;

1995
Acute pancreatitis induced by codeine-acetaminophen association: a case report with positive rechallenge.
    Pancreas, 1996, Volume: 13, Issue:3

    Topics: Acetaminophen; Aged; Codeine; Glucagon; Humans; Male; Pancreatitis; Parenteral Nutrition

1996
Paracetamol-induced pancreatitis and fulminant hepatitis in a hemodialysis patient.
    Clinical nephrology, 1997, Volume: 48, Issue:2

    Topics: Acetaminophen; Acute Disease; Aged; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury

1997
Adding methionine to way paracetamol tablet. Methionine is important in treatment of chronic pancreatitis.
    BMJ (Clinical research ed.), 1998, Feb-07, Volume: 316, Issue:7129

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chronic Disease; Drug Combinations; Humans; Methio

1998
Acetaminophen-codeine combination induced acute pancreatitis.
    Pancreas, 1998, Volume: 16, Issue:4

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Codeine; Female; Humans; Narcotics; P

1998
Pancytopenia, hyperglycemia, shock, coma, rhabdomyolysis, and pancreatitis associated with acetaminophen poisoning.
    Veterinary and human toxicology, 2001, Volume: 43, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adult; Anti-Inflammatory Agents, Non-Steroidal; Coma; Diagnosis, Diff

2001
Paracetamol-induced acute pancreatitis.
    British medical journal, 1977, Mar-19, Volume: 1, Issue:6063

    Topics: Acetaminophen; Acute Disease; Adult; Female; Humans; Pancreatitis; Suicide, Attempted

1977
Paracetamol-induced acute pancreatitis.
    British medical journal, 1977, Apr-23, Volume: 1, Issue:6068

    Topics: Acetaminophen; Acute Disease; Adult; Female; Humans; Pancreatitis

1977
Acetaminophen induced pancreatitis.
    Journal of toxicology. Clinical toxicology, 1991, Volume: 29, Issue:2

    Topics: Acetaminophen; Acute Disease; Adult; Ascites; Charcoal; Female; Humans; Ipecac; Kidney Diseases; Liv

1991
Danazol induced pancreatitis and hepatitis.
    Clinical rheumatology, 1990, Volume: 9, Issue:2

    Topics: Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Cimetidine; Danazol; Female; Humans; L

1990
Hemorrhagic pancreatitis associated with acetaminophen overdose.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:7

    Topics: Abdomen, Acute; Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Hemorrhage; Humans; Ki

1986
Enhanced toxicity of acetaminophen in alcoholics: report of three cases.
    Journal of clinical gastroenterology, 1985, Volume: 7, Issue:1

    Topics: Acetaminophen; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Drug Interactions; Ethanol

1985