acetaminophen has been researched along with Pain, Intractable in 19 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The objective of this study was to investigate the efficacy and safety of an extended-release, twice-daily fixed combination of 75 mg tramadol/650 mg paracetamol (DDS-06C) in the treatment of moderate-to-severe pain, using acute low back pain as a model." | 9.16 | Extended-release tramadol/paracetamol in moderate-to-severe pain: a randomized, placebo-controlled study in patients with acute low back pain. ( Bouchard, S; Lasko, B; Levitt, RJ; Rainsford, KD; Robertson, S; Rozova, A, 2012) |
| "Long-term treatment with tramadol LP once daily is generally safe in patients with osteoarthritis or refractory low back pain." | 9.11 | Long-term tolerability of tramadol LP, a new once-daily formulation, in patients with osteoarthritis or low back pain. ( Coffiner, M; Fontaine, D; Malonne, H; Peretz, A; Sereno, A; Sonet, B; Vanderbist, F, 2005) |
| "A multicenter, double-blind, cross-over, random-order study compared the efficacy of floctafenin, 800 mg/day and acetaminophen, 3000 mg/day, in providing pain relief to 192 patients with chronic pain due to osteoarthritis in the lower limbs." | 9.08 | Floctafenin versus acetaminophen for pain control in patients with osteoarthritis in the lower limbs. Franco-Belgian Task Force. ( du Laurier, MV; Fannius, J; Lequesne, M; Reginster, JY; Verdickt, W, 1997) |
| " The objective of this study was to investigate the efficacy and safety of an extended-release, twice-daily fixed combination of 75 mg tramadol/650 mg paracetamol (DDS-06C) in the treatment of moderate-to-severe pain, using acute low back pain as a model." | 5.16 | Extended-release tramadol/paracetamol in moderate-to-severe pain: a randomized, placebo-controlled study in patients with acute low back pain. ( Bouchard, S; Lasko, B; Levitt, RJ; Rainsford, KD; Robertson, S; Rozova, A, 2012) |
| "Long-term treatment with tramadol LP once daily is generally safe in patients with osteoarthritis or refractory low back pain." | 5.11 | Long-term tolerability of tramadol LP, a new once-daily formulation, in patients with osteoarthritis or low back pain. ( Coffiner, M; Fontaine, D; Malonne, H; Peretz, A; Sereno, A; Sonet, B; Vanderbist, F, 2005) |
| "A multicenter, double-blind, cross-over, random-order study compared the efficacy of floctafenin, 800 mg/day and acetaminophen, 3000 mg/day, in providing pain relief to 192 patients with chronic pain due to osteoarthritis in the lower limbs." | 5.08 | Floctafenin versus acetaminophen for pain control in patients with osteoarthritis in the lower limbs. Franco-Belgian Task Force. ( du Laurier, MV; Fannius, J; Lequesne, M; Reginster, JY; Verdickt, W, 1997) |
| " In both groups, if pain intensity was rated as > 3 on the VAS at week 1 or 2, the dosage was doubled." | 2.73 | Codeine/acetaminophen and hydrocodone/acetaminophen combination tablets for the management of chronic cancer pain in adults: a 23-day, prospective, double-blind, randomized, parallel-group study. ( Angel, AM; Castillo, JM; Del Pilar Castillo, M; Nuñez, PD; Ortiz, Y; Restrepo, JM; Rodriguez, JM; Rodriguez, MF; Rodriguez, RF, 2007) |
| "Refractory cancer pain that does not respond to standard opioid and/or co-analgesic therapy occurs in 10-20 % of patients." | 2.52 | Pharmacological options for the management of refractory cancer pain-what is the evidence? ( Afsharimani, B; Good, P; Hardy, J; Kindl, K, 2015) |
| "Managing persistent pain is challenging, particularly in older adults who often have comorbidities and physiological changes that affect dosing and adverse effect profiles." | 2.47 | Pharmacological management of persistent pain in older persons: focus on opioids and nonopioids. ( Gloth, FM, 2011) |
| "On the other hand, certain tumors require local blockade as in cases with pancreatic or perianal tumors." | 1.27 | [Therapy of pain caused by gastrointestinal tumors]. ( Zenz, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (26.32) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yokotsuka, S | 1 |
| Kato, J | 1 |
| Dwyer, JP | 1 |
| Jayasekera, C | 1 |
| Nicoll, A | 1 |
| Giamarellos-Bourboulis, EJ | 1 |
| Spyridaki, A | 1 |
| Savva, A | 1 |
| Georgitsi, M | 1 |
| Tsaganos, T | 1 |
| Mouktaroudi, M | 1 |
| Raftogiannis, M | 1 |
| Antonopoulou, A | 1 |
| Papaziogas, V | 1 |
| Baziaka, F | 1 |
| Sereti, K | 1 |
| Christopoulos, P | 1 |
| Marioli, A | 1 |
| Kanni, T | 1 |
| Maravitsa, P | 1 |
| Pantelidou, I | 1 |
| Leventogiannis, K | 1 |
| Tsiaoussis, P | 1 |
| Lymberopoulou, K | 1 |
| Koutelidakis, IM | 1 |
| Afsharimani, B | 1 |
| Kindl, K | 1 |
| Good, P | 1 |
| Hardy, J | 1 |
| Gloth, FM | 1 |
| Lasko, B | 1 |
| Levitt, RJ | 1 |
| Rainsford, KD | 1 |
| Bouchard, S | 1 |
| Rozova, A | 1 |
| Robertson, S | 1 |
| Davis, MP | 1 |
| Srivastava, M | 1 |
| Malonne, H | 1 |
| Coffiner, M | 1 |
| Fontaine, D | 1 |
| Sonet, B | 1 |
| Sereno, A | 1 |
| Peretz, A | 1 |
| Vanderbist, F | 1 |
| Rodriguez, RF | 2 |
| Castillo, JM | 2 |
| Del Pilar Castillo, M | 1 |
| Nuñez, PD | 1 |
| Rodriguez, MF | 2 |
| Restrepo, JM | 2 |
| Rodriguez, JM | 1 |
| Ortiz, Y | 1 |
| Angel, AM | 2 |
| Grantham, EG | 1 |
| Castillo, MP | 1 |
| Montoya, O | 1 |
| Daza, P | 1 |
| León, ME | 1 |
| Degner, LF | 1 |
| Fujii, SH | 1 |
| Levitt, M | 1 |
| Price, RK | 1 |
| Latham, AN | 1 |
| Lequesne, M | 1 |
| Fannius, J | 1 |
| Reginster, JY | 1 |
| Verdickt, W | 1 |
| du Laurier, MV | 1 |
| Bannwarth, B | 1 |
| de Jong, RH | 1 |
| Rogers, AG | 1 |
| Zenz, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-blind, Randomized, Placebo-controlled Phase IV Clinical Study of the Efficacy and Safety of a New Formulation of Paracetamol for the Management of Fever of Infectious Origin[NCT02283203] | Phase 4 | 80 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
| [NCT00643383] | Phase 3 | 277 participants (Actual) | Interventional | 2008-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for acetaminophen and Pain, Intractable
| Article | Year |
|---|---|
Analgesia for the cirrhotic patient: a literature review and recommendations.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anti | 2014 |
Pharmacological options for the management of refractory cancer pain-what is the evidence?
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; B | 2015 |
Pharmacological management of persistent pain in older persons: focus on opioids and nonopioids.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2011 |
Demographics, assessment and management of pain in the elderly.
Topics: Acetaminophen; Adrenal Cortex Hormones; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agen | 2003 |
7 trials available for acetaminophen and Pain, Intractable
| Article | Year |
|---|---|
Intravenous paracetamol as an antipyretic and analgesic medication: the significance of drug metabolism.
Topics: Abdominal Pain; Acetaminophen; Adolescent; Adult; Aged; Female; Fever; Humans; Infections; Infusions | 2014 |
Extended-release tramadol/paracetamol in moderate-to-severe pain: a randomized, placebo-controlled study in patients with acute low back pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Dizziness; Double-Blind Method; Drug Admi | 2012 |
Long-term tolerability of tramadol LP, a new once-daily formulation, in patients with osteoarthritis or low back pain.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Drug Administration Sche | 2005 |
Codeine/acetaminophen and hydrocodone/acetaminophen combination tablets for the management of chronic cancer pain in adults: a 23-day, prospective, double-blind, randomized, parallel-group study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Double-Blind Method; Drug Comb | 2007 |
Hydrocodone/acetaminophen and tramadol chlorhydrate combination tablets for the management of chronic cancer pain: a double-blind comparative trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combina | 2008 |
Double-blind comparison of meptazinol (200 mg) and dextropropoxyphene/paracetamol in a multi-centre, general practice setting.
Topics: Acetaminophen; Adolescent; Adult; Aged; Azepines; Clinical Trials as Topic; Dextropropoxyphene; Doub | 1982 |
Floctafenin versus acetaminophen for pain control in patients with osteoarthritis in the lower limbs. Franco-Belgian Task Force.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cross | 1997 |
8 other studies available for acetaminophen and Pain, Intractable
| Article | Year |
|---|---|
[Tramadol/acetaminophen combination tablets].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Pain; Drug Combinations; Humans | 2013 |
Frontal lobotomy for the relief of intractable pain.
Topics: Acetaminophen; Frontal Lobe; Humans; Pain; Pain Management; Pain, Intractable; Personality; Personal | 1950 |
Implementing a program to control chronic pain of malignant disease for patients in an extended care facility.
Topics: Acetaminophen; Aged; Analgesics; Female; Humans; Male; Middle Aged; Morphine; Pain, Intractable; Ski | 1982 |
Management of cancer pain: adults. Agency for Health Care Policy and Research.
Topics: Acetaminophen; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Behavior Therapy; C | 1994 |
Is the WHO analgesic ladder for cancer pain management appropriate for rheumatology patients?
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Disease Management; Glucocortico | 1999 |
Drug therapy in cancer pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Neop | 1991 |
How to manage incident pain.
Topics: Acetaminophen; Breast Neoplasms; Drug Therapy, Combination; Female; Humans; Hydromorphone; Middle Ag | 1987 |
[Therapy of pain caused by gastrointestinal tumors].
Topics: Acetaminophen; Aspirin; Bone Diseases; Dipyrone; Humans; Injections, Epidural; Narcotics; Neoplasms; | 1987 |