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acetaminophen and Orthopedic Disorders

acetaminophen has been researched along with Orthopedic Disorders in 20 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"To compare the safety and efficacy of a new cyclooxygenase-2 inhibitor, valdecoxib, with those of an oxycodone-acetaminophen combination in patients with acute musculoskeletal pain."9.11Comparison of valdecoxib and an oxycodone-acetaminophen combination for acute musculoskeletal pain in the emergency department: a randomized controlled trial. ( Gulla, J; Lovell, SJ; Rodriguez, E; Singer, AJ; Taira, T; Wackett, A, 2004)
"In a randomized, double-blind prospective manner, patients received either 5 mg hydrocodone with 500 mg acetaminophen or 30 mg codeine with 500 mg acetaminophen to take on discharge from the ED and every four hours thereafter as needed for pain."9.07Hydrocodone versus codeine in acute musculoskeletal pain. ( Menegazzi, JJ; Paris, PM; Turturro, MA; Yealy, DM, 1991)
"Acetaminophen is a safe medication that should be considered first-line therapy."6.44Approach to managing musculoskeletal pain: acetaminophen, cyclooxygenase-2 inhibitors, or traditional NSAIDs? ( Choquette, D; Craig, BN; Davis, P; De Angelis, C; Fulthorpe, G; Habal, F; Hunt, RH; Stewart, JI; Turpie, AG, 2007)
"To compare the safety and efficacy of a new cyclooxygenase-2 inhibitor, valdecoxib, with those of an oxycodone-acetaminophen combination in patients with acute musculoskeletal pain."5.11Comparison of valdecoxib and an oxycodone-acetaminophen combination for acute musculoskeletal pain in the emergency department: a randomized controlled trial. ( Gulla, J; Lovell, SJ; Rodriguez, E; Singer, AJ; Taira, T; Wackett, A, 2004)
"There was no statistical difference in the mean reduction in pain score between any of the combinations at any point, although combination therapy was the first to reach a clinically significant reduction in pain score (<13 mm), and diclofenac-paracetamol combinations consistently produced a greater reduction in mean pain score than either nonsteroidal antiinflammatory drugs or paracetamol alone."5.11Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury. ( Lam, PK; Man, SY; Rainer, TH; Woo, WW, 2005)
"In a randomized, double-blind prospective manner, patients received either 5 mg hydrocodone with 500 mg acetaminophen or 30 mg codeine with 500 mg acetaminophen to take on discharge from the ED and every four hours thereafter as needed for pain."5.07Hydrocodone versus codeine in acute musculoskeletal pain. ( Menegazzi, JJ; Paris, PM; Turturro, MA; Yealy, DM, 1991)
"Pain treatment with acetaminophen was not inferior to that with diclofenac or the combination of acetaminophen and diclofenac in acute minor musculoskeletal extremity trauma, both in rest and with movement."2.87Acetaminophen or Nonsteroidal Anti-Inflammatory Drugs in Acute Musculoskeletal Trauma: A Multicenter, Double-Blind, Randomized, Clinical Trial. ( Goddijn, H; Goslings, JC; Hollmann, MW; Kemper, EM; Lirk, P; Ridderikhof, ML; Schinkel, E; Van Dieren, S; Vandewalle, E, 2018)
"Ibuprofen was statistically equivalent to paracetamol and better tolerated than aspirin (p <0."2.70Comparative tolerability of paracetamol, aspirin and ibuprofen for short-term analgesia in patients with musculoskeletal conditions: results in 4291 patients. ( Le Parc, JM; Moore, N; Schneid, H; Van Ganse, E; Verrière, F; Wall, R, 2002)
"Acetaminophen is a safe medication that should be considered first-line therapy."2.44Approach to managing musculoskeletal pain: acetaminophen, cyclooxygenase-2 inhibitors, or traditional NSAIDs? ( Choquette, D; Craig, BN; Davis, P; De Angelis, C; Fulthorpe, G; Habal, F; Hunt, RH; Stewart, JI; Turpie, AG, 2007)
"Chronic pain has a growing incidence with age."2.43[Management strategies for the treatment of non malignant chronic pain in the elderly]. ( Perrot, S, 2006)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.00)18.2507
2000's9 (45.00)29.6817
2010's8 (40.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Bettiol, A1
Marconi, E1
Vannacci, A1
Simonetti, M1
Magni, A1
Cricelli, C1
Lapi, F1
Ridderikhof, ML2
Lirk, P2
Goddijn, H2
Vandewalle, E1
Schinkel, E1
Van Dieren, S2
Kemper, EM1
Hollmann, MW2
Goslings, JC2
Saanen, J1
Van Etten-Jamaludin, F1
Korownyk, C1
Young, J1
Michael Allan, G1
Graudins, A1
Meek, R1
Parkinson, J1
Egerton-Warburton, D1
Meyer, A1
Barozzi, N1
Tett, SE1
Witkop, M1
Lambing, A1
Kachalsky, E1
Divine, G1
Rushlow, D1
Dinnen, J1
Braund, R1
Abbott, JH1
Bhaskar, E1
Sowmya, G1
Moorthy, S1
Schenk, JM1
Calip, GS1
Tangen, CM1
Goodman, P1
Parsons, JK1
Thompson, IM1
Kristal, AR1
Lovell, SJ1
Taira, T1
Rodriguez, E1
Wackett, A1
Gulla, J1
Singer, AJ1
Woo, WW1
Man, SY1
Lam, PK1
Rainer, TH1
Kean, WF2
Buchanan, WW1
Gøtzsche, PC1
Perrot, S1
Hunt, RH1
Choquette, D1
Craig, BN1
De Angelis, C1
Habal, F1
Fulthorpe, G1
Stewart, JI1
Turpie, AG1
Davis, P1
Rainsford, KD1
Kean, IR1
Wolford, R1
Kahler, J1
Mishra, P1
Vasilenko, P1
DeYoung, R1
Le Parc, JM1
Van Ganse, E1
Moore, N1
Wall, R1
Schneid, H1
Verrière, F1
Turturro, MA1
Paris, PM1
Yealy, DM1
Menegazzi, JJ1

Reviews

6 reviews available for acetaminophen and Orthopedic Disorders

ArticleYear
Paracetamol versus other analgesia in adult patients with minor musculoskeletal injuries: a systematic review.
    Emergency medicine journal : EMJ, 2019, Volume: 36, Issue:8

    Topics: Acetaminophen; Adult; Analgesia; Analgesics; Humans; Musculoskeletal Diseases; Pain; Pain Management

2019
Assessment of acute and persistent pain management in patients with haemophilia.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2011, Volume: 17, Issue:4

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents,

2011
The use of NSAIDs in rheumatic disorders 2005: a global perspective.
    Inflammopharmacology, 2005, Volume: 13, Issue:4

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxyge

2005
[Management strategies for the treatment of non malignant chronic pain in the elderly].
    Psychologie & neuropsychiatrie du vieillissement, 2006, Volume: 4, Issue:3

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Humans; Musculos

2006
Approach to managing musculoskeletal pain: acetaminophen, cyclooxygenase-2 inhibitors, or traditional NSAIDs?
    Canadian family physician Medecin de famille canadien, 2007, Volume: 53, Issue:7

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cyclooxygenase 2 Inhi

2007
Management of chronic musculoskeletal pain in the elderly: opinions on oral medication use.
    Inflammopharmacology, 2008, Volume: 16, Issue:2

    Topics: Acetaminophen; Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antipain; Chroni

2008

Trials

8 trials available for acetaminophen and Orthopedic Disorders

ArticleYear
Acetaminophen or Nonsteroidal Anti-Inflammatory Drugs in Acute Musculoskeletal Trauma: A Multicenter, Double-Blind, Randomized, Clinical Trial.
    Annals of emergency medicine, 2018, Volume: 71, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2018
A randomised controlled trial of paracetamol and ibuprofen with or without codeine or oxycodone as initial analgesia for adults with moderate pain from limb injury.
    Emergency medicine Australasia : EMA, 2016, Volume: 28, Issue:6

    Topics: Acetaminophen; Adult; Aged; Analgesia; Analgesics; Codeine; Double-Blind Method; Drug Therapy, Combi

2016
Indications for and use of nonsteroidal antiinflammatory drugs and the risk of incident, symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial.
    American journal of epidemiology, 2012, Jul-15, Volume: 176, Issue:2

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cohort Studies; Co

2012
Comparison of valdecoxib and an oxycodone-acetaminophen combination for acute musculoskeletal pain in the emergency department: a randomized controlled trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2004, Volume: 11, Issue:12

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Bli

2004
Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury.
    Annals of emergency medicine, 2005, Volume: 46, Issue:4

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dizziness; Female; Humans

2005
A prospective comparison of transnasal butorphanol and acetaminophen with codeine for the relief of acute musculoskeletal pain.
    The American journal of emergency medicine, 1997, Volume: 15, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Butorphanol; Humans; Musculoskeletal Di

1997
Comparative tolerability of paracetamol, aspirin and ibuprofen for short-term analgesia in patients with musculoskeletal conditions: results in 4291 patients.
    Clinical rheumatology, 2002, Volume: 21, Issue:1

    Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Female; Ga

2002
Hydrocodone versus codeine in acute musculoskeletal pain.
    Annals of emergency medicine, 1991, Volume: 20, Issue:10

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Codeine; Double-Blind Method; Drug Combinatio

1991

Other Studies

6 other studies available for acetaminophen and Orthopedic Disorders

ArticleYear
Effectiveness of ibuprofen plus paracetamol combination on persistence of acute musculoskeletal disorders in primary care patients.
    International journal of clinical pharmacy, 2021, Volume: 43, Issue:4

    Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Midd

2021
Optimal pain relief for pediatric MSK injury.
    Canadian family physician Medecin de famille canadien, 2015, Volume: 61, Issue:6

    Topics: Acetaminophen; Analgesics; Canada; Child; Codeine; Drug Combinations; Humans; Ibuprofen; Morphine; M

2015
Non-steroidal anti-inflammatory drugs, Cyclooxygenase-2 inhibitors and paracetamol use in Queensland and in the whole of Australia.
    BMC health services research, 2008, Sep-24, Volume: 8

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Australia; Cyclooxy

2008
Nonsteroidal antiinflammatory drugs (NSAIDs) and paracetamol for acute musculoskeletal injuries: physiotherapists' understanding of which is safer, more effective, and when to initiate treatment.
    Physiotherapy theory and practice, 2011, Volume: 27, Issue:7

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2011
Musculoskeletal manifestations of dengue fever: is there a changing pattern?
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012, Volume: 18, Issue:2

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Dengue Viru

2012
[Paracetamol has the same effect as non-steroidal anti-inflammatory agents in acute musculoskeletal injuries].
    Ugeskrift for laeger, 2006, May-15, Volume: 168, Issue:20

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans

2006