acetaminophen has been researched along with Nervous System Diseases in 10 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| " IV and PO APAP doses administered with a predose pain score ≥4 within 1 h of dosing were compared." | 5.43 | Intravenous Versus Oral Acetaminophen for Pain Control in Neurocritical Care Patients. ( Brophy, GM; Nadpara, PA; Nichols, DC; Taylor, PD, 2016) |
| "Topical NSAIDs, followed by oral NSAIDs and acetaminophen with or without diclofenac, showed the most convincing and attractive benefit-harm ratio for patients with acute pain from non-low back, musculoskeletal injuries." | 5.05 | Management of Acute Pain From Non-Low Back, Musculoskeletal Injuries : A Systematic Review and Network Meta-analysis of Randomized Trials. ( Agarwal, A; Akbari-Kelachayeh, K; Ali, SH; Brar, S; Busse, JW; Chang, Y; Chen, E; Couban, R; Craigie, S; Culig, K; Das, A; Emary, P; Florez, ID; Goshua, A; Guyatt, GH; Hong, PJ; Lok, A; May, C; Morgan, RL; Noor, ST; Oparin, Y; Pozdnyakov, A; Ross, SA; Sadeghirad, B; Shergill, Y; Sivananthan, L; Yao, W; Zihayat, B, 2020) |
| "Of 200 consecutive breast cancer patients, 191 received the full package." | 2.75 | Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. ( Callesen, T; Gärtner, R; Kehlet, H; Kroman, N, 2010) |
| "Severity of headache, duration of migraine attack and overall efficacy of treatment were amongst the variables assessed in a randomized, double-blind, three-way cross-over comparison of 1 g paracetamol plus either domperidone 30 mg, domperidone 20 mg or placebo, taken at onset of headache." | 2.67 | Domperidone plus paracetamol in the treatment of migraine. ( Bancroft, K; MacGregor, EA; Wilkinson, M, 1993) |
| "Induction of fever is mediated by the release of pyrogenic cytokines (tumor necrosis factor α, interleukin 1, interleukin 6, and interferons)." | 2.55 | Paracetamol in fever in critically ill patients-an update. ( Chiumello, D; Gotti, M; Vergani, G, 2017) |
| " IV and PO APAP doses administered with a predose pain score ≥4 within 1 h of dosing were compared." | 1.43 | Intravenous Versus Oral Acetaminophen for Pain Control in Neurocritical Care Patients. ( Brophy, GM; Nadpara, PA; Nichols, DC; Taylor, PD, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Busse, JW | 1 |
| Sadeghirad, B | 1 |
| Oparin, Y | 1 |
| Chen, E | 1 |
| Goshua, A | 1 |
| May, C | 1 |
| Hong, PJ | 1 |
| Agarwal, A | 1 |
| Chang, Y | 1 |
| Ross, SA | 1 |
| Emary, P | 1 |
| Florez, ID | 1 |
| Noor, ST | 1 |
| Yao, W | 1 |
| Lok, A | 1 |
| Ali, SH | 1 |
| Craigie, S | 1 |
| Couban, R | 1 |
| Morgan, RL | 1 |
| Culig, K | 1 |
| Brar, S | 1 |
| Akbari-Kelachayeh, K | 1 |
| Pozdnyakov, A | 1 |
| Shergill, Y | 1 |
| Sivananthan, L | 1 |
| Zihayat, B | 1 |
| Das, A | 1 |
| Guyatt, GH | 1 |
| Nichols, DC | 1 |
| Nadpara, PA | 1 |
| Taylor, PD | 1 |
| Brophy, GM | 1 |
| Chiumello, D | 1 |
| Gotti, M | 1 |
| Vergani, G | 1 |
| Gärtner, R | 1 |
| Kroman, N | 1 |
| Callesen, T | 1 |
| Kehlet, H | 1 |
| Egi, M | 1 |
| MacGregor, EA | 1 |
| Wilkinson, M | 1 |
| Bancroft, K | 1 |
| Park, BK | 1 |
| Pirmohamed, M | 1 |
| Kitteringham, NR | 1 |
| Hollister, LE | 1 |
| Morgan, SP | 1 |
| Williams, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combined General Anesthesia Plus Paravertebral Block Versus General Anesthesia Plus Opioid Analgesia for Breast Cancer Surgery: A Prospective Randomized Trial[NCT01904266] | 60 participants (Actual) | Interventional | 2013-05-31 | Completed | |||
| Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study[NCT04875559] | 236 participants (Actual) | Observational [Patient Registry] | 2021-04-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for acetaminophen and Nervous System Diseases
| Article | Year |
|---|---|
Management of Acute Pain From Non-Low Back, Musculoskeletal Injuries : A Systematic Review and Network Meta-analysis of Randomized Trials.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Administration, Topical; Analgesics, Opioid; Anti-I | 2020 |
Paracetamol in fever in critically ill patients-an update.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Critical Illness; Cyclooxygenase | 2017 |
[Fever in non-neurological critically ill patients; friends or foe?].
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Clinical Trials as T | 2011 |
The role of cytochrome P450 enzymes in hepatic and extrahepatic human drug toxicity.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Chemical and Drug Induced Liver Injury; Cytochrome P-450 | 1995 |
Effective use of analgesic drugs.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ast | 1976 |
3 trials available for acetaminophen and Nervous System Diseases
| Article | Year |
|---|---|
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Domperidone plus paracetamol in the treatment of migraine.
Topics: Acetaminophen; Adolescent; Adult; Aged; Domperidone; Double-Blind Method; Drug Combinations; Female; | 1993 |
A comparison of three methods of managing fever in the neurologic patient.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Baths; Evaluation Studies as Topic; Female; Fever; Hu | 1990 |
2 other studies available for acetaminophen and Nervous System Diseases
| Article | Year |
|---|---|
Intravenous Versus Oral Acetaminophen for Pain Control in Neurocritical Care Patients.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 | 2016 |
Hepatic encephalopathy.
Topics: Acetaminophen; Ammonia; Animals; Brain; Brain Edema; Diet Therapy; Dopamine; Female; Humans; Lactulo | 1973 |