acetaminophen has been researched along with Myocardial Ischemia in 10 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "35 mmol/l acetaminophen administered 10 min after the onset of a 20-min period of global, low-flow myocardial ischemia was investigated." | 7.71 | Acetaminophen and low-flow myocardial ischemia: efficacy and antioxidant mechanisms. ( Merrill, GF, 2002) |
| "Acetaminophen is a commonly used alternative to nonsteroidal anti-inflammatory drugs, which have recently been demonstrated to increase mortality after acute myocardial infarction (AMI)." | 5.33 | Role of acetaminophen in acute myocardial infarction. ( Gorman, JH; Gorman, RC; Hinmon, R; Jackson, BM; Leshnower, BG; Parish, LM; Plappert, T; Sakamoto, H; Zeeshan, A, 2006) |
| "Acetaminophen was administered acutely at the onset of reperfusion after 20 min of low-flow, global myocardial ischemia in isolated, perfused guinea pig hearts (Langendorff) to evaluate its influence in the postischemia, reperfused myocardium." | 3.71 | Acetaminophen in the post-ischemia reperfused myocardium. ( Golfetti, R; Merrill, G; Rork, T; Spiler, N; VanDyke, K, 2002) |
| "The acute administration of acetaminophen to isolated, perfused guinea pig hearts appears to have cardioprotective effects against the injury/mechanical dysfunction caused by global, low-flow, myocardial ischemia and reperfusion." | 3.71 | Antioxidant properties of acetaminophen and cardioprotection. ( Goldberg, E; Merrill, GF, 2001) |
| "35 mmol/l acetaminophen administered 10 min after the onset of a 20-min period of global, low-flow myocardial ischemia was investigated." | 3.71 | Acetaminophen and low-flow myocardial ischemia: efficacy and antioxidant mechanisms. ( Merrill, GF, 2002) |
| "Acetaminophen or paracetamol, a commonly used over-the-counter analgesic, is known to elicit severe adverse reactions when taken in overdose, chronically at therapeutic dosage or, sporadically, following single assumptions of a therapeutic dose." | 1.39 | Possible fatal acetaminophen intoxication with atypical clinical presentation. ( Carbone, A; Chiarotti, M; d'Aloja, E; De-Giorgio, F; Lodise, M; Valerio, L, 2013) |
| "Acetaminophen is a commonly used alternative to nonsteroidal anti-inflammatory drugs, which have recently been demonstrated to increase mortality after acute myocardial infarction (AMI)." | 1.33 | Role of acetaminophen in acute myocardial infarction. ( Gorman, JH; Gorman, RC; Hinmon, R; Jackson, BM; Leshnower, BG; Parish, LM; Plappert, T; Sakamoto, H; Zeeshan, A, 2006) |
| " We conclude that chronic administration of acetaminophen provides cardioprotection to the postischemic, reperfused rodent myocardium." | 1.32 | Chronically administered acetaminophen and the ischemia/reperfused myocardium. ( Golfetti, R; Merrill, G; Rork, T, 2003) |
| "Acetaminophen is a phenol with antioxidant properties, but little is known about its actions on the mammalian myocardium and coronary circulation." | 1.31 | Coronary and myocardial effects of acetaminophen: protection during ischemia-reperfusion. ( McConnell, P; Merrill, G; Powell, S; Vandyke, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (80.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De-Giorgio, F | 1 |
| Lodise, M | 1 |
| Chiarotti, M | 1 |
| d'Aloja, E | 1 |
| Carbone, A | 1 |
| Valerio, L | 1 |
| Jacob, S | 1 |
| Cherian, P | 1 |
| Preusz, C | 1 |
| Kovacs, R | 1 |
| Mohr, NM | 1 |
| Fuller, BM | 1 |
| Skrupky, LP | 1 |
| Moy, H | 1 |
| Alunday, R | 1 |
| Micek, ST | 1 |
| Fagley, RE | 1 |
| Golfetti, R | 2 |
| VanDyke, K | 2 |
| Rork, T | 2 |
| Spiler, N | 1 |
| Merrill, G | 3 |
| Spiler, NM | 1 |
| Rork, TH | 1 |
| Merrill, GF | 3 |
| Leshnower, BG | 1 |
| Sakamoto, H | 1 |
| Zeeshan, A | 1 |
| Parish, LM | 1 |
| Hinmon, R | 1 |
| Plappert, T | 1 |
| Jackson, BM | 1 |
| Gorman, JH | 1 |
| Gorman, RC | 1 |
| McConnell, P | 1 |
| Powell, S | 1 |
| Goldberg, E | 1 |
1 review available for acetaminophen and Myocardial Ischemia
| Article | Year |
|---|---|
An old drug with a new purpose: cardiovascular actions of acetaminophen (paracetamol).
Topics: Acetaminophen; Animals; Cardiotonic Agents; Humans; Myocardial Ischemia; Myocardium | 2005 |
9 other studies available for acetaminophen and Myocardial Ischemia
| Article | Year |
|---|---|
Possible fatal acetaminophen intoxication with atypical clinical presentation.
Topics: Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Disseminated Intravascular Coagulation | 2013 |
Heartbreaking case of acetaminophen poisoning.
Topics: Acetaminophen; Adult; Electrocardiography; Fatal Outcome; Female; Humans; Myocardial Ischemia | 2008 |
Clinical and demographic factors associated with antipyretic use in gram-negative severe sepsis and septic shock.
Topics: Academic Medical Centers; Acetaminophen; Adult; Aged; Antipyretics; Bacteremia; Cohort Studies; Fema | 2011 |
Acetaminophen in the post-ischemia reperfused myocardium.
Topics: Acetaminophen; Animals; Creatine Kinase; Female; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myoc | 2002 |
Chronically administered acetaminophen and the ischemia/reperfused myocardium.
Topics: Acetaminophen; Animals; Cardiotonic Agents; Coronary Circulation; Creatine Kinase; Female; Guinea Pi | 2003 |
Role of acetaminophen in acute myocardial infarction.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Animals; Apoptosis; Body Temperature; Corona | 2006 |
Coronary and myocardial effects of acetaminophen: protection during ischemia-reperfusion.
Topics: Acetaminophen; Animals; Coronary Circulation; Coronary Vessels; Cytoprotection; Dose-Response Relati | 2001 |
Antioxidant properties of acetaminophen and cardioprotection.
Topics: Acetaminophen; Action Potentials; Analgesics, Non-Narcotic; Animals; Antioxidants; Cardiotonic Agent | 2001 |
Acetaminophen and low-flow myocardial ischemia: efficacy and antioxidant mechanisms.
Topics: Acetaminophen; Animals; Antioxidants; Cardiotonic Agents; Disease Models, Animal; Guinea Pigs; Heart | 2002 |