acetaminophen has been researched along with Musculoskeletal Pain in 25 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Musculoskeletal Pain: Discomfort stemming from muscles, LIGAMENTS, tendons, and bones.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with acute pain were randomized to receive oxycodone/acetaminophen (Oxy) or acetaminophen (APAP)." | 9.51 | Oxycodone induced euphoria in ED patients with acute musculoskeletal pain. A secondary analysis of data from a randomized trial. ( Adewunmi, V; Friedman, BW; Gupta, C; Sapkota, A; Takematsu, M; Williams, AR, 2022) |
| "Among patients with acute musculoskeletal pain refractory to oral ibuprofen, oxycodone/acetaminophen resulted in slightly greater pain relief than acetaminophen, but this was associated with more medication-related adverse events." | 9.41 | A randomized controlled trial of oxycodone/acetaminophen versus acetaminophen alone for emergency department patients with musculoskeletal pain refractory to ibuprofen. ( Bijur, PE; Borrayes, L; Costa, V; Feliciano, C; Friedman, BW; Irizarry, E; Izzo, AJ; Restivo, A, 2021) |
| "In elderly trauma patients (age ≥65 years) with 1 or more rib fractures, PO acetaminophen is equivalent to IV acetaminophen for pain control, with no difference in morbidity or mortality." | 9.34 | Treatment With Oral Versus Intravenous Acetaminophen in Elderly Trauma Patients With Rib Fractures: A Prospective Randomized Trial. ( Antill, AC; Bollig, RW; Daley, BJ; Ford, BR; Frye, SW; Haynes, JC; McMillen, JC, 2020) |
| "Intravenous dexketoprofen seemed to achieve superior analgesia to intravenous paracetamol when compared with all pain locations in patients with non-traumatic musculoskeletal pain." | 9.30 | Intravenous dexketoprofen versus paracetamol in non-traumatic musculoskeletal pain in the emergency department: A randomized clinical trial. ( Arikan, C; Demirozogul, E; Ozen, M; Seyit, M; Turkcuer, I; Yilmaz, A, 2019) |
| "Patients with acute pain were randomized to receive oxycodone/acetaminophen (Oxy) or acetaminophen (APAP)." | 5.51 | Oxycodone induced euphoria in ED patients with acute musculoskeletal pain. A secondary analysis of data from a randomized trial. ( Adewunmi, V; Friedman, BW; Gupta, C; Sapkota, A; Takematsu, M; Williams, AR, 2022) |
| "In elderly trauma patients (age ≥65 years) with 1 or more rib fractures, PO acetaminophen is equivalent to IV acetaminophen for pain control, with no difference in morbidity or mortality." | 5.34 | Treatment With Oral Versus Intravenous Acetaminophen in Elderly Trauma Patients With Rib Fractures: A Prospective Randomized Trial. ( Antill, AC; Bollig, RW; Daley, BJ; Ford, BR; Frye, SW; Haynes, JC; McMillen, JC, 2020) |
| "Intravenous dexketoprofen seemed to achieve superior analgesia to intravenous paracetamol when compared with all pain locations in patients with non-traumatic musculoskeletal pain." | 5.30 | Intravenous dexketoprofen versus paracetamol in non-traumatic musculoskeletal pain in the emergency department: A randomized clinical trial. ( Arikan, C; Demirozogul, E; Ozen, M; Seyit, M; Turkcuer, I; Yilmaz, A, 2019) |
| "Of 104 older patients initiating analgesic treatment following ED visits for musculoskeletal pain, 71 patients took opioid-containing analgesics, 15 took acetaminophen, and 18 took ibuprofen." | 3.79 | Side effects from oral opioids in older adults during the first week of treatment for acute musculoskeletal pain. ( Dickey, RM; Esserman, DA; Fillingim, RB; Hunold, KM; Isaacs, CG; McLean, SA; Pereira, GF; Platts-Mills, TF; Sloane, PD, 2013) |
| " Although factors such as route of administration or dosage may explain some heterogeneity, more work is needed to identify which subgroups will have a more favorable benefit-risk balance for one analgesic over another." | 2.82 | Effectiveness of Opioid Analgesic Medicines Prescribed in or at Discharge From Emergency Departments for Musculoskeletal Pain : A Systematic Review and Meta-analysis. ( Abdel Shaheed, C; Dinh, M; Harris, IA; Jamshidi, M; Jones, CMP; Lin, CC; Maher, CG; Mathieson, S; Patanwala, AE, 2022) |
| "Osteoarthritis is a common progressive disease in older adults, and those affected often have impaired physical function, co-existing disease states, and reduced quality of life." | 2.55 | Move it or Lose it. Is it Reasonable for Older Adults with Osteoarthritis to Continue to Use Paracetamol in Order to Maintain Physical Activity? ( Cooke, J; Cooper, G; Lee, K; Shield, A, 2017) |
| " Chronic use of strong opioids can induce hyperalgesia in some patients." | 2.52 | Strong opioids for noncancer pain due to musculoskeletal diseases: Not more effective than acetaminophen or NSAIDs. ( Berthelot, JM; Darrieutort-Lafitte, C; Le Goff, B; Maugars, Y, 2015) |
| "Osteoarthritis is a common debilitating condition affecting a substantial portion of the population and is an accepted consequence of ageing and overuse." | 1.56 | Why are we still using opioids for osteoarthritis? ( Oettinger, J; Yip, K, 2020) |
| "While acute musculoskeletal pain is a frequent complaint, its management is often neglected." | 1.43 | A nurse-initiated pain protocol in the ED improves pain treatment in patients with acute musculoskeletal pain. ( Berben, SA; Doggen, CJ; Gaakeer, MI; IJzerman, MJ; Pierik, JG; van Eenennaam, FL; van Vugt, AB, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 17 (68.00) | 24.3611 |
| 2020's | 8 (32.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marwaha, S | 1 |
| Sapkota, A | 1 |
| Takematsu, M | 1 |
| Adewunmi, V | 1 |
| Gupta, C | 1 |
| Williams, AR | 1 |
| Friedman, BW | 2 |
| Jones, CMP | 1 |
| Lin, CC | 1 |
| Jamshidi, M | 1 |
| Abdel Shaheed, C | 1 |
| Maher, CG | 1 |
| Harris, IA | 1 |
| Patanwala, AE | 1 |
| Dinh, M | 1 |
| Mathieson, S | 1 |
| Katsuki, M | 1 |
| Matsumori, Y | 1 |
| Kashiwagi, K | 1 |
| Kawamura, S | 1 |
| Koh, A | 1 |
| Yip, K | 1 |
| Oettinger, J | 1 |
| Ali, S | 1 |
| Rajagopal, M | 1 |
| Klassen, T | 1 |
| Richer, L | 1 |
| McCabe, C | 1 |
| Willan, A | 1 |
| Yaskina, M | 1 |
| Heath, A | 1 |
| Drendel, AL | 1 |
| Offringa, M | 1 |
| Gouin, S | 1 |
| Stang, A | 1 |
| Sawyer, S | 1 |
| Bhatt, M | 1 |
| Hickes, S | 1 |
| Poonai, N | 1 |
| Antill, AC | 1 |
| Frye, SW | 1 |
| McMillen, JC | 1 |
| Haynes, JC | 1 |
| Ford, BR | 1 |
| Bollig, RW | 1 |
| Daley, BJ | 1 |
| Irizarry, E | 1 |
| Feliciano, C | 1 |
| Izzo, AJ | 1 |
| Borrayes, L | 1 |
| Restivo, A | 1 |
| Costa, V | 1 |
| Bijur, PE | 2 |
| Casey, SD | 1 |
| Stevenson, DE | 1 |
| Mumma, BE | 1 |
| Slee, C | 1 |
| Wolinsky, PR | 1 |
| Hirsch, CH | 1 |
| Tyler, K | 1 |
| Steurer, J | 1 |
| Jevsevar, DS | 1 |
| Shores, PB | 1 |
| Mullen, K | 1 |
| Schulte, DM | 1 |
| Brown, GA | 1 |
| Cummins, DS | 1 |
| Yilmaz, A | 2 |
| Sabirli, R | 1 |
| Ozen, M | 2 |
| Turkcuer, I | 2 |
| Erdur, B | 1 |
| Arikan, C | 2 |
| Demirozogul, E | 2 |
| Sarohan, A | 1 |
| Seyit, M | 2 |
| Ok, N | 1 |
| Gong, J | 1 |
| Colligan, M | 1 |
| Kirkpatrick, C | 1 |
| Jones, P | 1 |
| Spence, D | 1 |
| Bondarsky, EE | 1 |
| Domingo, AT | 1 |
| Matuza, NM | 1 |
| Taylor, MB | 1 |
| Thode, HC | 1 |
| Singer, AJ | 1 |
| Hunold, KM | 1 |
| Esserman, DA | 1 |
| Isaacs, CG | 1 |
| Dickey, RM | 1 |
| Pereira, GF | 1 |
| Fillingim, RB | 1 |
| Sloane, PD | 1 |
| McLean, SA | 1 |
| Platts-Mills, TF | 1 |
| Richette, P | 1 |
| Hill, CL | 1 |
| March, LM | 1 |
| Aitken, D | 1 |
| Lester, SE | 1 |
| Battersby, R | 1 |
| Hynes, K | 1 |
| Fedorova, T | 1 |
| Proudman, SM | 1 |
| James, M | 1 |
| Cleland, LG | 1 |
| Jones, G | 1 |
| Berthelot, JM | 1 |
| Darrieutort-Lafitte, C | 1 |
| Le Goff, B | 1 |
| Maugars, Y | 1 |
| Chang, AK | 1 |
| Holden, L | 1 |
| Gallagher, EJ | 1 |
| Bruyère, O | 1 |
| Cooper, C | 1 |
| Pelletier, JP | 1 |
| Maheu, E | 1 |
| Rannou, F | 1 |
| Branco, J | 1 |
| Luisa Brandi, M | 1 |
| Kanis, JA | 1 |
| Altman, RD | 1 |
| Hochberg, MC | 1 |
| Martel-Pelletier, J | 1 |
| Reginster, JY | 1 |
| Pierik, JG | 1 |
| Berben, SA | 1 |
| IJzerman, MJ | 1 |
| Gaakeer, MI | 1 |
| van Eenennaam, FL | 1 |
| van Vugt, AB | 1 |
| Doggen, CJ | 1 |
| Young, SE | 1 |
| Bothwell, JD | 1 |
| Walsh, RM | 1 |
| Lee, K | 1 |
| Cooke, J | 1 |
| Cooper, G | 1 |
| Shield, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Study of Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries: The No OUCH Trials[NCT03767933] | Phase 2 | 710 participants (Actual) | Interventional | 2019-04-20 | Completed | ||
| The Effect of Different Intra-articular Injections on Pain and Function in Primary Gonarthrosis[NCT05291793] | 80 participants (Actual) | Interventional | 2020-04-01 | Completed | |||
| Comparison of Efficacy of Intravenous Paracetamol and Dexketoprofen for Acute Traumatic Musculoskeletal Pain in the Emergency Department: A Double-Blinded, Randomized, Controlled Trial[NCT03428503] | Phase 4 | 200 participants (Actual) | Interventional | 2015-12-31 | Completed | ||
| Comparison of Efficacy of Intravenous Paracetamol and Dexketoprofen for Acute Nontraumatic Musculoskeletal Pain in the Emergency Department: A Double-Blinded, Randomized, Controlled Trial[NCT03122314] | Phase 4 | 200 participants (Actual) | Interventional | 2015-08-31 | Completed | ||
| Nurses' Knowledge and Attitudes Towards Opioids in Pain Management in North Cyprus[NCT04252443] | 127 participants (Actual) | Interventional | 2018-06-01 | Completed | |||
| Aromatherapy for Management of Back Pain in the Emergency Department[NCT03377088] | 60 participants (Anticipated) | Interventional | 2017-12-11 | Recruiting | |||
| Double Blind, Placebo Controlled Trial to Evaluate the Effects of a Nutraceutical Containing High-Molecular-Weight Hyaluronic Acid (HA) and Acetyl-11-Keto-Beta-Boswellic Acid (AKBA) in Patients Affected by Knee Osteoarthritis[NCT03612986] | 72 participants (Actual) | Interventional | 2018-08-22 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for acetaminophen and Musculoskeletal Pain
| Article | Year |
|---|---|
Effectiveness of Opioid Analgesic Medicines Prescribed in or at Discharge From Emergency Departments for Musculoskeletal Pain : A Systematic Review and Meta-analysis.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Emerg | 2022 |
Mixed Treatment Comparisons for Nonsurgical Treatment of Knee Osteoarthritis: A Network Meta-analysis.
Topics: Acetaminophen; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 2018 |
Strong opioids for noncancer pain due to musculoskeletal diseases: Not more effective than acetaminophen or NSAIDs.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Drug Tolerance; Humans; | 2015 |
Safely Managing Acute Osteoarthritis in the Emergency Department: An Evidence-Based Review.
Topics: Acetaminophen; Acute Disease; Administration, Cutaneous; Administration, Oral; Adrenal Cortex Hormon | 2016 |
Move it or Lose it. Is it Reasonable for Older Adults with Osteoarthritis to Continue to Use Paracetamol in Order to Maintain Physical Activity?
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Exercise; Humans; Medication Adherence; Motor Activit | 2017 |
11 trials available for acetaminophen and Musculoskeletal Pain
| Article | Year |
|---|---|
Oxycodone induced euphoria in ED patients with acute musculoskeletal pain. A secondary analysis of data from a randomized trial.
Topics: Acetaminophen; Acute Pain; Analgesics, Opioid; Double-Blind Method; Drug Combinations; Euphoria; Hum | 2022 |
Study protocol for two complementary trials of non-steroidal or opioid analgesia use for children aged 6 to 17 years with musculoskeletal injuries (the No OUCH study).
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2020 |
Treatment With Oral Versus Intravenous Acetaminophen in Elderly Trauma Patients With Rib Fractures: A Prospective Randomized Trial.
Topics: Acetaminophen; Acute Pain; Administration, Intravenous; Administration, Oral; Aged; Aged, 80 and ove | 2020 |
A randomized controlled trial of oxycodone/acetaminophen versus acetaminophen alone for emergency department patients with musculoskeletal pain refractory to ibuprofen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Emergency Service, | 2021 |
Topics: Acetaminophen; Adult; Codeine; Double-Blind Method; Drug Combinations; Emergency Service, Hospital; | 2018 |
Intravenous paracetamol versus dexketoprofen in acute musculoskeletal trauma in the emergency department: A randomised clinical trial.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agent | 2019 |
Intravenous dexketoprofen versus paracetamol in non-traumatic musculoskeletal pain in the emergency department: A randomized clinical trial.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agent | 2019 |
Oral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Analgesics; Codeine; Double-Blind Meth | 2019 |
Ibuprofen vs acetaminophen vs their combination in the relief of musculoskeletal pain in the ED: a randomized, controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blin | 2013 |
Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose.
Topics: Acetaminophen; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Cartilage, Art | 2016 |
Comparative Analgesic Efficacy of Oxycodone/Acetaminophen Versus Hydrocodone/Acetaminophen for Short-term Pain Management in Adults Following ED Discharge.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Double-Blind Method; Drug Combinations; Emergency Serv | 2015 |
9 other studies available for acetaminophen and Musculoskeletal Pain
| Article | Year |
|---|---|
JK.
Topics: Accidents, Traffic; Acetaminophen; Analgesics, Opioid; Anxiety; Drug Combinations; Family Relations; | 2021 |
Efficacy of Kampo medicine Kakkonto as acute medication to treat tension-type headache among musculoskeletal pain patients using regular analgesics.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Female; Humans; Male; Medicine, Kampo; Middle Ag | 2023 |
Why are we still using opioids for osteoarthritis?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2020 |
Emergency Department Pain Management Following Implementation of a Geriatric Hip Fracture Program.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Cr | 2017 |
Bad medicine: co-codamol.
Topics: Acetaminophen; Analgesics, Opioid; Behavior, Addictive; Codeine; Drug Combinations; Drug Overdose; G | 2013 |
Side effects from oral opioids in older adults during the first week of treatment for acute musculoskeletal pain.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Sectional Studies; Emergenc | 2013 |
How safe is acetaminophen in rheumatology?
Topics: Acetaminophen; Cardiovascular Diseases; Chronic Pain; Humans; Musculoskeletal Pain; Osteoarthritis; | 2014 |
A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting.
Topics: Acetaminophen; Analgesics; Chondroitin Sulfates; Evidence-Based Medicine; Glucosamine; Humans; Muscu | 2016 |
A nurse-initiated pain protocol in the ED improves pain treatment in patients with acute musculoskeletal pain.
Topics: Acetaminophen; Adult; Analgesics; Diclofenac; Emergency Service, Hospital; Female; Fentanyl; Follow- | 2016 |