acetaminophen has been researched along with Multiple Sclerosis in 6 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether low-dose prednisone reduces flu-like symptoms at the initiation of interferon beta 1-b (IFNbeta-1b), we studied 71 patients with clinically definite, relapsing-remitting multiple sclerosis who were started on IFNbeta-1b." | 5.08 | Low-dose steroids reduce flu-like symptoms at the initiation of IFNbeta-1b in relapsing-remitting MS. ( Marzo, ME; Montalban, X; Nos, C; Río, J; Tintoré, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Conte, WL | 1 |
| Arndt, N | 1 |
| Cipriani, VP | 1 |
| Dellaria, A | 1 |
| Javed, A | 1 |
| Francis, GS | 1 |
| Kaplowitz, N | 1 |
| Alteri, E | 1 |
| Río, J | 3 |
| Nos, C | 1 |
| Marzo, ME | 1 |
| Tintoré, M | 2 |
| Montalban, X | 3 |
| Martínez-Cáceres, EM | 1 |
| Barrau, M | 1 |
| Durán, I | 1 |
| Borrás, C | 1 |
| Gallagher, RM | 1 |
| Stewart, FI | 1 |
| Weissbein, T | 1 |
| Weissbein, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Trial of Prednisone and Acetaminophen Versus Acetaminophen Alone in Minimizing Flu-like Symptoms From Pegylated Interferon Beta-1a[NCT03424733] | Phase 4 | 50 participants (Anticipated) | Interventional | 2017-09-25 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for acetaminophen and Multiple Sclerosis
| Article | Year |
|---|---|
Low-dose steroids reduce flu-like symptoms at the initiation of IFNbeta-1b in relapsing-remitting MS.
Topics: Acetaminophen; Adjuvants, Immunologic; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, | 1998 |
Amelioration of flulike symptoms at the onset of interferon beta-1b therapy in multiple sclerosis by low-dose oral steroids is related to a decrease in interleukin-6 induction.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Dr | 1998 |
4 other studies available for acetaminophen and Multiple Sclerosis
| Article | Year |
|---|---|
Reduction in ocrelizumab-induced infusion reactions by a modified premedication protocol.
Topics: Acetaminophen; Administration, Intravenous; Adult; Age Factors; Anti-Inflammatory Agents; Antibodies | 2019 |
Liver injury associated with the beta-interferons for MS.
Topics: Acetaminophen; Alanine Transaminase; Chemical and Drug Induced Liver Injury, Chronic; Humans; Interf | 2004 |
Ibuprofen treatment versus gradual introduction of interferon beta-1b in patients with MS.
Topics: Acetaminophen; Drug Administration Schedule; Fever; Humans; Hypothalamus; Ibuprofen; Interferon beta | 2000 |
Nonnarcotic analgesic abuse. A common biopsychosocial problem.
Topics: Acetaminophen; Aged; Analgesics; Behavior Therapy; Female; Humans; Marriage; Multiple Sclerosis; Pai | 1988 |