acetaminophen has been researched along with Migraine Disorders in 197 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report an asthmatic adolescent female who had anaphylaxis with 650 mg acetaminophen after tolerating 325-mg doses for years." | 7.69 | Acetaminophen anaphylaxis with aspirin and sodium salicylate sensitivity: a case report. ( Ham Pong, A; Schwarz, N, 1996) |
| "Migrainous vertigo is a common cause of dizziness presenting to an otorhinolaryngology/otoneurology clinic." | 6.79 | Flunarizine in the prophylaxis of migrainous vertigo: a randomized controlled trial. ( Amalanathan, S; Augustine, AM; Balraj, A; Lepcha, A; Tyagi, AK, 2014) |
| " Additional studies are needed to assess the relationship between caffeine dosing and clinical benefits in patients with TTH and migraine." | 6.55 | Caffeine in the management of patients with headache. ( Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS, 2017) |
| "The results of this subgroup analysis confirm that the fixed combination of ASA (250 mg), paracetamol (200 mg), and caffeine (50 mg) is effective and well tolerated in a broad spectrum from mild to severe migraine and tension-type headache severity independently of the headache diagnosis." | 5.15 | The efficacy and tolerability of a fixed combination of acetylsalicylic acid, paracetamol, and caffeine in patients with severe headache: a post-hoc subgroup analysis from a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel g ( Aicher, B; Diener, HC; Peil, H, 2011) |
| " In a randomized double-blind study including individuals with either migraine or tension-type headache (TTH) we showed significant superiority of the fixed combination of acetylsalicylic acid + paracetamol + caffeine over the combination without caffeine, the single preparations, and placebo in the treatment of headache." | 5.14 | Headache classification by history has only limited predictive value for headache episodes treated in controlled trials with OTC analgesics. ( Aicher, B; Diener, HC; Lipton, RB; Pageler, L; Peil, H; Pfaffenrath, V, 2009) |
| "We investigated efficacy, safety, and tolerability of two tablets of the fixed combination of 250 mg acetylsalicylic acid (ASA) + 200 mg paracetamol + 50 mg caffeine (Thomapyrin) in comparison with two tablets of 250 mg ASA + 200 mg paracetamol, two tablets of 500 mg ASA, two tablets of 500 mg paracetamol, two tablets of 50 mg caffeine, and placebo in patients who were used to treating their episodic tension-type headache or migraine attacks with non-prescription analgesics." | 5.11 | The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group st ( Aicher, B; Diener, HC; Pageler, L; Peil, H; Pfaffenrath, V, 2005) |
| " The aim of this study was to compare the effectiveness and tolerability of a fixed combination of domperidone and paracetamol (Domperamol; Servier), which has anti-nauseant and anti-emetic activity, with sumatriptan 50 mg in moderate to severe migraine." | 5.09 | Comparison of a fixed combination of domperidone and paracetamol (Domperamol) with sumatriptan 50 mg in moderate to severe migraine: a randomised UK primary care study. ( Ball, K; Dowson, A; Haworth, D, 2000) |
| " For the acute treatment of migraine attacks or tension-type headache, ibuprofen (10 mg per kg body weight) or acetaminophen (15 mg per kg body weight) are recommended with highest evidence, intranasal sumatriptan (10 to 20 mg) can be given as second choice." | 4.81 | [Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)]. ( Evers, S; Gerber, WD; Naumann, E; Pothmann, R; Uberall, M, 2002) |
| "A prediction model development study was completed using the 2006 American Migraine Prevalence and Prevention Study survey, from participants who were aged ≥18, met criteria and headache day frequency for episodic migraine, did not take prescription medication for migraine, and used ≥1 of the following acute migraine medication classes: acetaminophen, aspirin, NSAIDs, or caffeine containing combination products (CCP)." | 4.12 | Predictive models for determining treatment response to nonprescription acute medications in migraine: Results from the American Migraine Prevalence and Prevention Study. ( Armand, CE; Buse, DC; Ezzati, A; Fanning, KM; Lipton, RB; Martin, VT; Pavlovic, JM; Reed, ML, 2022) |
| " However, long-term use of NSAIDs is associated with side-effects, mainly involving the gastrointestinal tract." | 3.77 | [Migraine and non-steroidal anti-inflammatory agents]. ( Pradalier, A; Vincent, D, 1992) |
| "We report an asthmatic adolescent female who had anaphylaxis with 650 mg acetaminophen after tolerating 325-mg doses for years." | 3.69 | Acetaminophen anaphylaxis with aspirin and sodium salicylate sensitivity: a case report. ( Ham Pong, A; Schwarz, N, 1996) |
| "In spite of clinical differences between transformed migraine and tension headache, which may help diagnosis, in our series abuse of analgesics (including ergotamine) was a common characteristic." | 3.69 | [Clinical features of daily chronic headache]. ( Iñiguez, C; Larrodé, P; Mauri, JA; Morales, F, 1997) |
| "The severity and frequency of migraine attacks were measured prior to the study, at weeks 2, 4, 8, and 12." | 2.94 | The Efficacy of Topical Basil Essential Oil on Relieving Migraine Headaches: A Randomized Triple-Blind Study. ( Ahmadifard, M; Ardalan, A; Bahrami, P; Ebrahimzadeh, F; Sheikhi, E; Yarahmadi, S, 2020) |
| "Many migraine patients rely on over-the-counter analgesics for the treatment of migraine attacks." | 2.82 | Aspirin, paracetamol (acetaminophen) and caffeine for the treatment of acute migraine attacks: A systemic review and meta-analysis of randomized placebo-controlled trials. ( Diener, HC; Gaul, C; Lehmacher, W; Weiser, T, 2022) |
| "Migrainous vertigo is a common cause of dizziness presenting to an otorhinolaryngology/otoneurology clinic." | 2.79 | Flunarizine in the prophylaxis of migrainous vertigo: a randomized controlled trial. ( Amalanathan, S; Augustine, AM; Balraj, A; Lepcha, A; Tyagi, AK, 2014) |
| "Migraine is a common form of headache that is a major burden for patients who often seek emergency care." | 2.79 | Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial. ( Akdag, Ö; Eken, C; Elicabuk, H; Kiray, C; Serinken, M; Turkcuer, I; Uyan, E; Yilmaz, A, 2014) |
| "In patients with severe baseline migraine pain, AAC and IB are significantly more effective than PLA, and AAC provides significantly faster and more effective pain relief than IB." | 2.79 | Results of a multicenter, double-blind, randomized, parallel-group, placebo-controlled, single-dose study comparing the fixed combination of acetaminophen, acetylsalicylic acid, and caffeine with ibuprofen for acute treatment of patients with severe migra ( Gold, M; Goldstein, J; Hagen, M, 2014) |
| "Rizatriptan was found more efficacious than conventional therapy in terminating an attack of migraine and its' associated symptoms but looking into the contra-indications, side-effects and cost of the former there has been limitation in its prescription as well as the use." | 2.79 | Clinicopharmacological comparative study of rizatriptan versus conventional therapy in migraine. ( Kushwah, A; Tomar, A, 2014) |
| " Drug-related adverse events were noted in 8 patients with 1,000 mg paracetamol, in 9 patients with 400 mg etodolac and in 9 patients for 800 mg etodolac during the study." | 2.78 | Efficacy and safety of 400 and 800 mg etodolac vs. 1,000 mg paracetamol in acute treatment of migraine: a randomized, double-blind, crossover, multicenter, phase III clinical trial. ( Baykan, B; Ertaş, M; Özge, A; Öztürk, V; Sirin, H, 2013) |
| "Migraine is a widespread, relapsing, remittent syndrome." | 2.77 | Efficacy, end points and eventualities: sumatriptan/naproxen versus butalbital/paracetamol/caffeine in the treatment of migraine. ( Fox, AW, 2012) |
| "Telcagepant is an oral calcitonin gene-related peptide receptor antagonist which is being evaluated for the acute treatment of migraine." | 2.76 | Randomized controlled study of telcagepant plus ibuprofen or acetaminophen in migraine. ( Brandes, J; Ceesay, P; Gottwald, R; Hewitt, DJ; Ho, TW; Lines, C; Lipton, RB; Martin, V; Schaefer, E, 2011) |
| "Metoclopramide is a well-known anti-emetic drug with central and peripheral pharmacological effects." | 2.76 | Metoclopramide as an analgesic in severe migraine attacks: an open, single-blind, parallel control study. ( Cuello, D; Fragoso, M; Salazar, G; Sergio, P; Vergez, L, 2011) |
| "Acetaminophen 1000 mg was significantly more effective than placebo for all but 1 (pain reduced to none at 2 hours) clinically important secondary pain relief outcomes." | 2.75 | A randomized, placebo-controlled trial of acetaminophen for treatment of migraine headache. ( Codispoti, JR; Fu, M; Prior, MJ, 2010) |
| "Acetaminophen has been studied for acute migraine treatment." | 2.73 | Efficacy and tolerability of coadministration of rizatriptan and acetaminophen vs rizatriptan or acetaminophen alone for acute migraine treatment. ( Diamond, M; Diamond, S; Freitag, F; Janssen, I; Rodgers, A; Skobieranda, F, 2008) |
| "For patients with migraine, who fail to improve after treatment with a first-line medication, it is reasonable to use an intravenous NSAID or intravenous acetaminophen." | 2.72 | Second-line interventions for migraine in the emergency department: A narrative review. ( Fakherddine, M; Friedman, BW; Kazi, F; Manyapu, M; Mekuria, K, 2021) |
| "A total of 1555 migraineurs were included in the analysis." | 2.72 | Acetaminophen, aspirin, and caffeine in combination versus ibuprofen for acute migraine: results from a multicenter, double-blind, randomized, parallel-group, single-dose, placebo-controlled study. ( Goldstein, J; Lipton, RB; Ryan, RE; Saper, JR; Silberstein, SD, 2006) |
| "Eletriptan was well-tolerated; 6 (3." | 2.71 | Eletriptan treatment of migraine in patients switching from barbiturate-containing analgesics: results from a multiple-attack study. ( Almas, M; Hilliard, B; Loder, E; Martin, VT; Taylor, K, 2005) |
| "Most people who experience migraine use OTC medications to treat their symptoms, but no head-to-head clinical trials comparing these agents with prescription migraine therapies have been published." | 2.71 | Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial. ( Baggish, J; Battikha, JP; Elkind, AH; Gallagher, RM; Goldstein, J; Hoffman, H; Saper, JR; Silberstein, SD; Smith, TR, 2005) |
| "In the acute migraine attack patients were treated intravenously with either 1000mg paracetamol (acetaminophen) or placebo." | 2.71 | Evaluation of the efficacy of intravenous acetaminophen in the treatment of acute migraine attacks: a double-blind, placebo-controlled parallel group multicenter study. ( Evers, S; Jürgens, T; Kaempfe, N; Kraemer, C; Leinisch, E; May, A; Sostak, P; Straube, A, 2005) |
| "As part of the stratified treatment of migraine, those patients whose headaches are mild or moderate may benefit from nontriptan medications." | 2.70 | Comparative study of a combination of isometheptene mucate, dichloralphenazone with acetaminophen and sumatriptan succinate in the treatment of migraine. ( Cady, R; DiSerio, F; Elkind, A; Freitag, FG; Gallagher, RM; Goldstein, J; Klapper, JA; Rapoport, AM; Sadowsky, C; Saper, JR; Smith, TR, 2001) |
| "The most severely disabled segment of migraineurs, including those whose attacks usually required bed rest, or who vomited 20% or more of the time, were excluded." | 2.69 | Efficacy and safety of acetaminophen, aspirin, and caffeine in alleviating migraine headache pain: three double-blind, randomized, placebo-controlled trials. ( Lipton, RB; Ryan, RE; Saper, J; Sheftell, F; Silberstein, S; Stewart, WF, 1998) |
| "For both menstruation-associated migraine and migraine not associated with menses, the proportion of subjects with pain intensity reduced to mild or none (responders) was significantly greater with AAC than with placebo at all postdose time points from 0." | 2.69 | Treatment of menstruation-associated migraine with the nonprescription combination of acetaminophen, aspirin, and caffeine: results from three randomized, placebo-controlled studies. ( Armellino, JJ; Battikha, JP; Hamelsky, SW; Hoffman, HD; Lipton, RB; Silberstein, SD; Stewart, WF, 1999) |
| "Ibuprofen was twice as likely as acetaminophen to abort migraine within 2 hours." | 2.68 | Ibuprofen or acetaminophen for the acute treatment of migraine in children: a double-blind, randomized, placebo-controlled, crossover study. ( Hämäläinen, ML; Hoppu, K; Santavuori, P; Valkeila, E, 1997) |
| "Zolmitriptan was well tolerated after all treatment regimens." | 2.68 | The novel anti-migraine compound zolmitriptan (Zomig 311C90) has no clinically significant interactions with paracetamol or metoclopramide. ( Layton, G; Peck, RW; Posner, J; Ridout, G; Seaber, EJ, 1997) |
| "Severity of headache, duration of migraine attack and overall efficacy of treatment were amongst the variables assessed in a randomized, double-blind, three-way cross-over comparison of 1 g paracetamol plus either domperidone 30 mg, domperidone 20 mg or placebo, taken at onset of headache." | 2.67 | Domperidone plus paracetamol in the treatment of migraine. ( Bancroft, K; MacGregor, EA; Wilkinson, M, 1993) |
| "Forty-six patients with acute migraine attacks were treated with intramuscular injection of 75 mg diclofenac sodium, and another group of forty patients with intramuscular injection of paracetamol." | 2.67 | Treatment of acute migraine attack with diclofenac sodium: a double-blind study. ( Chrisikos, N; Fotiadou, A; Karabetsos, A; Karachalios, GN; Kehagioglou, K, 1992) |
| " Dosage was repeated after 2 h if the attack had not abated." | 2.67 | Randomized double-blind comparison of tolfenamic acid and paracetamol in migraine. ( Andersen, B; Christiansen, LV; Larsen, BH; Olesen, J, 1990) |
| "25 mg), codeine phosphate (8 mg) and paracetamol (500 mg) had any effect on the bioavailability of the analgesics." | 2.66 | The relative bioavailability of paracetamol and codeine after oral administration of a combination of buclizine, paracetamol and codeine, with or without docusate, and of paracetamol alone in healthy volunteers. ( Johnson, ES; Merrington, D; Oliver, W; Persaud, N, 1985) |
| "Forty ambulant migraine patients were supplied with oral medication for six consecutive attacks; metoclopramide 10 mg was administered in all attacks, and paracetamol 500 mg and mefenamic acid 500 mg for three attacks each." | 2.65 | Double blind comparison of mefenamic acid and acetaminophen (paracetamol) in migraine. ( Peatfield, RC; Petty, RG; Rose, FC, 1983) |
| "The relief of acute migraine attacks with an analgesic/antihistamine combination containing paracetamol, codeine phosphate, doxylamine succinate and caffeine (Mersyndol) compared with that achieved with a placebo has been studied in a double-blind, crossover trial." | 2.64 | Treatment of migraine attacks with an analgesic combination (Mersyndol). ( Somerville, BW, 1976) |
| "The new migraine preparation Migraeflux has been subjected to clinical trial in a double-blind cross-over study in 32 single tests." | 2.64 | [Therapy of migraine. Clinical experience with Migraeflux, a new migraine drug]. ( Philipp, M, 1977) |
| "Migraine is increasingly recognized as an extremely burdensome and disabling disorder in both children and adolescents." | 2.61 | Pharmacotherapy for acute migraines in children and adolescents. ( Barbanti, P; Egeo, G; Grazzi, L, 2019) |
| "The management of migraine is multifaceted and is generally dichotomized into acute and preventive strategies, with several treatment modalities." | 2.58 | Migraine Treatment: Current Acute Medications and Their Potential Mechanisms of Action. ( De Felice, M; Ong, JJY, 2018) |
| "The use of melatonin for migraine showed that (i) reduced the number of days with pain and the analgesic consumption when compared with placebo, (ii) no benefits on headache intensity, number of headache days and analgesics consumption when compared with amitriptyline, (iii) reduced the number of analgesic consumption, the attack frequency and the headache intensity when associated with propranolol plus nortriptyline vs placebo plus propranolol plus nortriptyline, and (iv) no difference for any of the interest outcomes when associated with propranolol plus nortriptyline vs sodium valproate plus propranolol plus nortriptyline." | 2.58 | Melatonin for preventing primary headache: A systematic review. ( Adriano Leal Freitas da Costa, A; de Oliveira Cruz Latorraca, C; Leite Pacheco, R; Luiza Cabrera Martimbianco, A; Riera, R; Vianna Pachito, D, 2018) |
| "The acute management of migraine should incorporate a stratified care model in concert with evidence-based treatment options." | 2.58 | Acute Treatment of Migraine. ( Vargas, BB, 2018) |
| " Additional studies are needed to assess the relationship between caffeine dosing and clinical benefits in patients with TTH and migraine." | 2.55 | Caffeine in the management of patients with headache. ( Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS, 2017) |
| "Ibuprofen was more effective than placebo for producing pain freedom at two hours in two small studies that included 162 children (RR 1." | 2.53 | Drugs for the acute treatment of migraine in children and adolescents. ( Billinghurst, L; Crumley, ET; Durec, T; Hartling, L; Klassen, TP; Linsdell, MA; Richer, L; Russell, K; Vandermeer, B, 2016) |
| "Rizatriptan was approved by Food and Drug Administration (FDA) (USA) for children and adolescents of 6-17 years." | 2.52 | Oral triptans in children and adolescents: an update. ( Sakai, F, 2015) |
| "As suboptimally treated migraine in pregnancy could have negative consequences for both mother and fetus, the primary aim of clinicians should be to provide optimal treatment according to stage of pregnancy, while minimising possible risks related to drug therapy." | 2.52 | Pharmacological treatment of migraine during pregnancy and breastfeeding. ( Amundsen, S; Nezvalová-Henriksen, K; Nordeng, H; Spigset, O; Stovner, LJ, 2015) |
| "Diagnosis of migraine headache in children can be difficult as it depends on subjective symptoms; diagnostic criteria are broader than in adults." | 2.52 | Migraine headache in children. ( Barnes, NP, 2015) |
| "Mild migraine attack can be treated with acetaminophen or NSAIDs either alone or combined with metoclopramide." | 2.52 | [Update on Current Care Guideline: Migraine]. ( , 2015) |
| "Once the diagnosis of migraine has been made, the ED physician is faced with the challenge of determining appropriate abortive treatment." | 2.50 | Pediatric migraine: abortive management in the emergency department. ( Meckler, GD; Sheridan, DC; Spiro, DM, 2014) |
| "Migraine is a common, disabling condition and a burden for the individual, health services and society." | 2.49 | Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults. ( Derry, S; Moore, RA, 2013) |
| "The TACs include cluster headache, paroxysmal hemicrania, and short-lasting neuralgiform headache attacks with conjunctival injection and tearing; hemicrania continua, although classified separately by the International Headache Society, shares many features of both migraine and the TACs." | 2.49 | Primary headache disorders. ( Benoliel, R; Eliav, E, 2013) |
| " For preventative treament of migraine, cyproheptadine should be reserved for younger children unable to swallow tablets while amitriptyline is preferred due to its once daily dosing and minimal side effects." | 2.48 | Treating pediatric migraine: an expert opinion. ( Hershey, AD; Kabbouche, MA; O'Brien, HL, 2012) |
| "Diagnosis of migraine headache in children can be difficult as it depends on subjective symptoms; diagnostic criteria are broader than in adults." | 2.47 | Migraine headache in children. ( Barnes, NP, 2011) |
| "Migraine is a common, disabling condition and a burden for the individual, health services and society." | 2.46 | Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults. ( Derry, S; McQuay, HJ; Moore, RA, 2010) |
| "Diagnosis of migraine headache in children can be difficult as it depends on subjective symptoms; diagnostic criteria are broader than in adults." | 2.45 | Migraine headache in children. ( Barnes, NP; James, EK, 2009) |
| "Medication overuse headache is a common feature underlying chronic headache, especially migraine." | 2.44 | Medication overuse headache. ( Couch, JR; Lenaerts, ME, 2007) |
| "In the acute migraine attack, a single dose of either ibuprofen 10 mg/kg or paracetamol 15 mg/kg has been shown to be effective, with only a few adverse effects." | 2.43 | [Pharmacologic treatment of acute migraine attack in children]. ( Auvin, S; Cuvellier, JC; Joriot, S; Vallée, L, 2005) |
| "Treatment of pediatric migraine includes an individually tailored regimen of both nonpharmacologic and pharmacologic measures." | 2.43 | Symptomatic treatment of migraine in children: a systematic review of medication trials. ( Berger, MY; Bruijn, JK; Damen, L; Koes, BW; Passchier, J; Verhagen, AP, 2005) |
| "Migraine is a typical "women's disease": the fluctuations of sex hormones, in particular estrogens, during woman's reproductive life show a direct and major influence on migraine course." | 2.42 | [Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies]. ( Airola, G; Allais, G; Benedetto, C; Bosio, A; Ciochetto, D; De Lorenzo, C; Mana, O; Quirico, PE; Terzi, MG, 2003) |
| "In over 40% of migraineurs the condition begins before 18 years of age." | 2.42 | Headache in children and adolescents: conventional and unconventional approaches to treatment. ( Grazzi, L, 2004) |
| "Most headaches are benign, but all require appropriate assessment." | 2.41 | "Nurse, my head hurts": a review of childhood headaches. ( Fisher, W; Gordon, V; Kolar, KR, 2001) |
| "Management of migraine patients with or without aura must include appropriate medication to treat the attack and long-term preventive therapy, especially if the frequency of the attacks is greater than 2-4 per month." | 2.40 | Medical treatment of migraine: from mechanisms of action to contraindications. ( Annoni, JM; Higelin, F, 1998) |
| "The occurrence of migraine in women is influenced by hormonal changes throughout the lifecycle." | 2.40 | Migraine in pregnancy: what are the safest treatment options? ( Pfaffenrath, V; Rehm, M, 1998) |
| "Efficacy of acute OTC medications for migraine varies greatly." | 1.91 | Predictors of treatment-response to caffeine combination products, acetaminophen, acetylsalicylic acid (aspirin), and nonsteroidal anti-inflammatory drugs in acute treatment of episodic migraine. ( Ezzati, A; Fanning, KM; Lipton, RB; Reed, ML, 2023) |
| "Women with migraine, rheumatoid arthritis and mental disease showed the highest risk of frequent use." | 1.91 | Paracetamol use prior to and in early pregnancy: Prevalence and patterns among women with and without chronic medical diseases. ( Damm, P; de Wolff, MG; Fisher, MB; Hagen, CP; Hegaard, HK; Rode, L; Rom, AL; Taagaard, M, 2023) |
| "Fifty children, with 116 migraine attacks, were included in the study (30 females; mean age 12; range 6-18)." | 1.72 | Migraine abortive treatment in children and adolescents in Israel. ( Cohen, R; Genizi, J; Lahoud, D, 2022) |
| "In 19 guidelines (10 for acute migraine, 9 for chronic knee OA) from 10 scientific societies (AAN/AHS, ACR/AF, CHS, EFNS, EHF/LTB, ESCEO, EULAR, SFEMC, SRF, OARSI) published between 1997 and 2021, methods, results and conclusions were compared, between guidelines and over time." | 1.72 | Practice guidelines for the treatment of acute migraine and chronic knee osteoarthritis with paracetamol: an expert appraisal on evolution over time between scientific societies. ( Attal, N; Desmeules, J; Eschalier, A; Lanteri-Minet, M; Perrot, S, 2022) |
| "In paediatric migraine, ibuprofen, acetaminophen and triptans are safe, effective therapies but there is scant paediatric data informing second-line emergency treatment." | 1.72 | Intravenous chlorpromazine for acute paediatric migraine. ( Babl, FE; Hill, A; Löllgen, RM; Mackay, MT; Palmer, GM, 2022) |
| "Prochlorperazine injection has been upgraded to a highly recommended level because of the rich clinical experience for this treatment." | 1.72 | 2022 Taiwan Guidelines for Acute Treatment of Migraine. ( Lau, CI; Wang, YF, 2022) |
| "Of 859,501 pregnancies, 8168 had migraine." | 1.62 | Polypharmacy and comorbidities during pregnancy in a cohort of women with migraine. ( Burch, RC; Hernandez-Diaz, S; Wood, ME, 2021) |
| "At baseline, mean monthly migraine days were 9." | 1.62 | Understanding the migraine treatment landscape prior to the introduction of calcitonin gene-related peptide inhibitors: Results from the Assessment of TolerabiliTy and Effectiveness in MigrAINe Patients using Preventive Treatment (ATTAIN) study. ( Dodick, DW; Kawata, AK; Lipton, RB; Poon, JL; Sapra, S; Shaffer, S; Shah, N; Shah, S; Tepper, SJ; Wilcox, TK, 2021) |
| "The pathogenesis of medication overuse headache (MOH) involves hyperexcitability of cortical and trigeminal neurons." | 1.51 | Altered activity in the nucleus raphe magnus underlies cortical hyperexcitability and facilitates trigeminal nociception in a rat model of medication overuse headache. ( le Grand, SM; Potewiratnanond, P; Srikiatkhachorn, A; Supronsinchai, W, 2019) |
| "Acetaminophen was the most frequent medicine administered first (53%, 38/72)." | 1.51 | Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study. ( Hamilton, KT; Robbins, MS, 2019) |
| "The Beck Depression Inventory, the ID Migraine™ screening tool, and the criteria of the International Headache Society were used to investigate the depressive symptoms and headache types." | 1.51 | Migraine, tension-type headache, and depression among Saudi female students in Taif University. ( Desouky, DE; Taha, AA; Zaid, HA, 2019) |
| "Migraine is a primary headache disorder characterized by recurrent attacks." | 1.48 | Acute Migraine Headache: Treatment Strategies. ( Mayans, L; Walling, A, 2018) |
| "Analgesic use in pregnancy is affected by migraine characteristics and intensity, and also by socio-demographic factors." | 1.46 | Patterns and predictors of analgesic use in pregnancy: a longitudinal drug utilization study with special focus on women with migraine. ( Eberhard-Gran, M; Harris, GE; Lundqvist, C; Nordeng, H; Wood, M, 2017) |
| "Headache is a common chronic neurologic disorder with huge economic and psychosocial impact." | 1.46 | Prevalence and clinical characteristics of headaches among undergraduate students in three tertiary institutions in Ilorin, Nigeria. ( Aderibigbe, SA; Adeyanju, OA; Desalu, OO; Kolo, PM; Mustapha, AF; Sanya, EO, 2017) |
| "In reply to a question, medication overuse headache is reviewed, acute and preventive medications are discussed, and quality of life is considered." | 1.43 | Medication Overuse Headache Due to Butalbital, Acetaminophen, and Caffeine Tablets. ( Feeney, R, 2016) |
| "The headache disorders, namely, migraine and tension type headache and the associated analgesic consumption is badly underestimated and thus makes a major current public health problem." | 1.43 | Management of headache and associated factors among undergraduate medicine and health science students of University of Gondar, North West Ethiopia. ( Abay, Z; Abdelwuhab, M; Basazn, A; Birru, EM; Sirak, B; Teni, FS, 2016) |
| "Migraine is common in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) but its treatment responses are not well described, and its relationship to stroke risk unknown." | 1.43 | CADASIL: Migraine, Encephalopathy, Stroke and Their Inter-Relationships. ( Markus, HS; Tan, RY, 2016) |
| "In the Netherlands, treatment of migraine is commonly performed by general practitioners (GPs)." | 1.40 | How general practitioners treat migraine in children--evaluation of a headache guideline. ( de Coo, IF; de Jong, G; van den Berg, JS; Zielman, R, 2014) |
| "Trauma triggered migraine is seen more frequently in children, adolescents and young adults." | 1.40 | [Footballer's migraine instead of concussion]. ( Borggreve, AG; Haan, J; Lansink, JG; van Oosterhout, WP, 2014) |
| "Glucose metabolic changes in CM patients taking different dosage of analgesic during headache-free periods and clear distinctions in several brain regions were observed." | 1.39 | Overuse of paracetamol caffeine aspirin powders affects cerebral glucose metabolism in chronic migraine patients. ( Di, W; Fang, Y; Luo, N; Miao, J; Qi, W; Shi, X; Tao, Y; Xiao, Z; Yi, C; Zhang, A; Zhang, X; Zhu, Y, 2013) |
| " Therefore, the proposed method is suitable for the routine control of these ingredients in multicomponent dosage forms." | 1.39 | Capillary electrophoretic determination of antimigraine formulations containing caffeine, ergotamine, paracetamol and domperidone or metoclopramide. ( Alshehri, MM; Alzoman, NZ; Elshahed, MS; Maher, HM; Olah, IV; Rizk, MS; Sultan, MA, 2013) |
| "About half of all patients with acute migraine obtain substantial relief after 2 hours with a single oral dose of paracetamol 1000 mg." | 1.38 | Migraine attacks: paracetamol first. ( , 2012) |
| "This study identified underdiagnosis of migraine, low use of migraine prophylaxis and triptans, and high prevalence of medication overuse among subjects seeking self-medication for regular headache." | 1.38 | [Self-medication of regular headache: a community pharmacy-based survey in Belgium]. ( Boussery, K; Christiaens, T; De Bolle, L; Evrard, B; Mehuys, E; Paemeleire, K; Philippe, G; Piette, M; Prévôt, ML; Remon, JP; Van Bortel, L; Van Hees, T; Van Tongelen, I, 2012) |
| "Migraine has been linked to immunologic disturbances, but the role of the immune system in chronic forms of headache that evolve from migraine has not been studied." | 1.37 | Analysis of leukocytes in medication-overuse headache, chronic migraine, and episodic migraine. ( Barea, LM; Barros, HM; Dantas, DC; Forcelini, CM; Luz, C; Santin, R; Stein, AT, 2011) |
| "The SMILE study was conducted among migraine patients consulting in primary care in France." | 1.35 | SMILE: first observational prospective cohort study of migraine in primary care in France. Description of methods and study population. ( Géraud, G; Joubert, JM; Lantéri-Minet, M; Lucas, C; Mekies, C; Radat, F; Valade, D; Vives, E, 2008) |
| "Of individuals with migraine, 42% reported consulting a health-care professional about their headaches." | 1.33 | Clinical characteristics and patterns of medication use of migraneurs in Latin America from 12 cities in 6 countries. ( Alarcon, F; Aranaga, N; Aulet, S; Chapman, E; Conterno, L; Estevez, E; Garcia-Pedroza, F; Garrido, J; Macias-Islas, M; Monzillo, P; Morillo, LE; Nunez, L; Plascencia, N; Rodriguez, C; Takeuchi, Y, 2005) |
| "To evaluate the proportion of migraineurs who are self-aware of their disease in France, to determine the factors (disability, quality of life, psychiatric comorbidities, and medical consultation) that may promote self-awareness of migraine, and to assess the influence of these factors on migraine attacks." | 1.33 | Recognition and therapeutic management of migraine in 2004, in France: results of FRAMIG 3, a French nationwide population-based survey. ( Chautard, MH; Géraud, G; Lantéri-Minet, M; Lucas, C; Valade, D, 2006) |
| "The sequence and timing of taking migraine medications, whether prescription or over-the-counter, and the patient's response to their treatment, is unknown." | 1.33 | Acute migraine treatment: patterns of use and satisfaction in a clinical population. ( Hopkins, M; Malik, SN; Silberstein, SD; Young, WB, 2006) |
| "A diagnosis of hemiplegic migraine was made." | 1.31 | [Hemiplegic migraine. A series of 5 patients]. ( Capodieci, C; Guala, A; Licardi, G; Peretti, M, 2000) |
| "The corresponding values for tension headache and controls were 0." | 1.30 | Platelet sulphotransferase activity, plasma sulphate levels and sulphation capacity in patients with migraine and tension headache. ( Alam, Z; Coombes, N; Steventon, GB; Waring, RH; Williams, AC, 1997) |
| "A 54 years-old man with a history of migraine, suffered from chest pain together with ST-segment elevation related to the intake of drugs against migraine attacks." | 1.29 | [Variant angina pectoris related to the treatment of migraine]. ( Cruz Fernández, JM; García Martínez, JT; García Rubira, JC; Gómez Barrado, JJ; González López, M; Hidalgo Urbano, R; Pérez Leal, I; Rodríguez Revuelta, M; Turégano Albarrán, S, 1995) |
| "We report five cases in which anorectal stenosis was associated with chronic administration of suppositories containing paracetamol and acetylsalicylic acid." | 1.29 | Anorectal stenosis in patients with prolonged use of suppositories containing paracetamol and acetylsalicylic acid. ( Adler, M; Cremer, M; Houben, JJ; Peny, MO; Van Gossum, A; Zalcman, M, 1993) |
| "An open trial was carried out in eight healthy male and female volunteers to examine the bioavailability as well as the main kinetic parameters of Migränerton (metoclopramide and paracetamol; CAS 364-64-5 and CAS 103-90-2, resp)." | 1.28 | [Pharmacokinetic aspects of a combination of metoclopramide and paracetamol. Results of a human kinetic study and consequences for migraine patients]. ( Becker, A; Berner, G; Leuschner, F; Vögtle-Junkert, U, 1992) |
| "The main treatment of the acute migraine attack remains sleep, sedation, an anti-nauseant and analgesics, and in some patients 1 or 2 mg of ergotamine tartrate." | 1.27 | Treatment of the acute migraine attack--current status. ( Wilkinson, M, 1983) |
| "The nausea was relieved in 71% of the patients by placebo and bed rest, but metoclopramide was significantly (p = 0." | 1.26 | A double blind study of metoclopramide in the treatment of migraine attacks. ( Aebelholt-Krabbe, A; Melgaard, B; Olesen, J; Tfelt-Hansen, P; Veilis, B, 1980) |
| "In an acute migraine clinic, patients were all treated with metoclopramide 10 mg i." | 1.26 | Paracetamol (acetaminophen) versus acetylsalicylic acid in migraine. ( Olesen, J; Tfelt-Hansen, P, 1980) |
| "A simple study of migraine was undertaken in an industrial setting to identify facts about the condition of migraine which had previously been unrecorded in industry." | 1.26 | Study of migraine and the treatment of acute attacks in industry. ( Harrop, C; Jones, A, 1980) |
| "Patients having one or more attacks of migraine a week may need prophylactic treatment." | 1.26 | [The use of drugs in migraine]. ( Wilkinson, M, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (19.29) | 18.7374 |
| 1990's | 38 (19.29) | 18.2507 |
| 2000's | 45 (22.84) | 29.6817 |
| 2010's | 58 (29.44) | 24.3611 |
| 2020's | 18 (9.14) | 2.80 |
| Authors | Studies |
|---|---|
| Danilov, AB | 1 |
| Chernyshov, OIu | 1 |
| Veĭn, AM | 1 |
| Kolosova, OA | 1 |
| Diener, HC | 6 |
| Gaul, C | 1 |
| Lehmacher, W | 1 |
| Weiser, T | 1 |
| Kazi, F | 1 |
| Manyapu, M | 1 |
| Fakherddine, M | 1 |
| Mekuria, K | 1 |
| Friedman, BW | 1 |
| Genizi, J | 1 |
| Lahoud, D | 1 |
| Cohen, R | 1 |
| Ezzati, A | 2 |
| Fanning, KM | 2 |
| Buse, DC | 1 |
| Pavlovic, JM | 1 |
| Armand, CE | 1 |
| Reed, ML | 2 |
| Martin, VT | 2 |
| Lipton, RB | 10 |
| Perrot, S | 1 |
| Eschalier, A | 1 |
| Desmeules, J | 1 |
| Lanteri-Minet, M | 3 |
| Attal, N | 1 |
| Löllgen, RM | 1 |
| Babl, FE | 1 |
| Mackay, MT | 1 |
| Hill, A | 1 |
| Palmer, GM | 1 |
| Lau, CI | 1 |
| Wang, YF | 1 |
| Taagaard, M | 1 |
| Rode, L | 1 |
| de Wolff, MG | 1 |
| Damm, P | 1 |
| Hagen, CP | 1 |
| Fisher, MB | 1 |
| Hegaard, HK | 1 |
| Rom, AL | 1 |
| Trønnes, JN | 1 |
| Wood, M | 2 |
| Lupattelli, A | 1 |
| Ystrom, E | 1 |
| Nordeng, H | 3 |
| Potewiratnanond, P | 1 |
| le Grand, SM | 1 |
| Srikiatkhachorn, A | 2 |
| Supronsinchai, W | 1 |
| Ahmadifard, M | 1 |
| Yarahmadi, S | 1 |
| Ardalan, A | 1 |
| Ebrahimzadeh, F | 1 |
| Bahrami, P | 1 |
| Sheikhi, E | 1 |
| Jamiolkowski, D | 1 |
| Steveling-Klein, E | 1 |
| Scherer Hofmeier, K | 1 |
| Hartmann, K | 1 |
| Pavithra, V | 1 |
| Mishra, D | 1 |
| Behera, S | 1 |
| Juneja, M | 1 |
| Panda, PK | 1 |
| Sharawat, IK | 1 |
| Singh, S | 1 |
| Chakrabarty, B | 1 |
| Costa, FM | 1 |
| Ferreira, IP | 1 |
| Mascarenhas, IF | 1 |
| Alves, CF | 1 |
| Bento, VA | 1 |
| Loureiro, HC | 1 |
| Wood, ME | 1 |
| Burch, RC | 1 |
| Hernandez-Diaz, S | 1 |
| Kawata, AK | 1 |
| Shah, N | 1 |
| Poon, JL | 1 |
| Shaffer, S | 1 |
| Sapra, S | 1 |
| Wilcox, TK | 1 |
| Shah, S | 1 |
| Tepper, SJ | 1 |
| Dodick, DW | 1 |
| Cevoli, S | 1 |
| Giannini, G | 1 |
| Favoni, V | 1 |
| Terlizzi, R | 1 |
| Sancisi, E | 1 |
| Nicodemo, M | 1 |
| Zanigni, S | 1 |
| Bacchi Reggiani, ML | 1 |
| Pierangeli, G | 1 |
| Cortelli, P | 1 |
| Harris, GE | 1 |
| Eberhard-Gran, M | 1 |
| Lundqvist, C | 1 |
| Prakash, S | 1 |
| Adroja, B | 1 |
| Parekh, H | 1 |
| Jeric, M | 1 |
| Surjan, N | 1 |
| Jelicic Kadic, A | 1 |
| Riva, N | 1 |
| Puljak, L | 1 |
| Robbins, MS | 2 |
| Garas, SY | 1 |
| Patel, K | 1 |
| Ong, JJY | 1 |
| De Felice, M | 1 |
| Sanya, EO | 1 |
| Desalu, OO | 1 |
| Aderibigbe, SA | 1 |
| Kolo, PM | 1 |
| Mustapha, AF | 1 |
| Adeyanju, OA | 1 |
| Mayans, L | 1 |
| Walling, A | 1 |
| Leite Pacheco, R | 1 |
| de Oliveira Cruz Latorraca, C | 1 |
| Adriano Leal Freitas da Costa, A | 1 |
| Luiza Cabrera Martimbianco, A | 1 |
| Vianna Pachito, D | 1 |
| Riera, R | 1 |
| Vargas, BB | 1 |
| Hamilton, KT | 1 |
| Barbanti, P | 1 |
| Grazzi, L | 2 |
| Egeo, G | 1 |
| Desouky, DE | 1 |
| Zaid, HA | 1 |
| Taha, AA | 1 |
| Israil, A | 1 |
| Ahmed, S | 1 |
| Rahman, KM | 1 |
| Uddin, MJ | 1 |
| Dey, SK | 1 |
| Battacharjee, M | 1 |
| Mondal, G | 1 |
| Ali, MA | 1 |
| Alam, MN | 1 |
| Miah, AH | 1 |
| Uddin, MS | 1 |
| Derry, S | 2 |
| Moore, RA | 2 |
| Gallelli, L | 1 |
| Avenoso, T | 1 |
| Falcone, D | 1 |
| Palleria, C | 1 |
| Peltrone, F | 1 |
| Esposito, M | 1 |
| De Sarro, G | 1 |
| Carotenuto, M | 1 |
| Guidetti, V | 1 |
| Benoliel, R | 1 |
| Eliav, E | 1 |
| Lepcha, A | 1 |
| Amalanathan, S | 1 |
| Augustine, AM | 1 |
| Tyagi, AK | 1 |
| Balraj, A | 1 |
| Turkcuer, I | 1 |
| Serinken, M | 1 |
| Eken, C | 1 |
| Yilmaz, A | 1 |
| Akdag, Ö | 1 |
| Uyan, E | 1 |
| Kiray, C | 1 |
| Elicabuk, H | 1 |
| Gupta, S | 1 |
| Oosthuizen, R | 1 |
| Pulfrey, S | 1 |
| Sheridan, DC | 1 |
| Spiro, DM | 1 |
| Meckler, GD | 1 |
| Goodacre, S | 1 |
| Goldstein, J | 5 |
| Hagen, M | 1 |
| Gold, M | 1 |
| de Coo, IF | 1 |
| de Jong, G | 1 |
| Zielman, R | 1 |
| van den Berg, JS | 1 |
| Zhang, A | 2 |
| Jiang, T | 1 |
| Luo, Y | 1 |
| Zheng, Z | 1 |
| Shi, X | 2 |
| Xiao, Z | 2 |
| Fang, Y | 2 |
| Lansink, JG | 1 |
| van Oosterhout, WP | 1 |
| Borggreve, AG | 1 |
| Haan, J | 1 |
| Hernández Martínez, A | 1 |
| Lázaro Sáez, M | 1 |
| Bendezú García, RA | 1 |
| Patrón Román, GO | 1 |
| Sakai, F | 1 |
| Amundsen, S | 1 |
| Nezvalová-Henriksen, K | 1 |
| Stovner, LJ | 1 |
| Spigset, O | 1 |
| Kushwah, A | 1 |
| Tomar, A | 1 |
| Yisarakun, W | 1 |
| Chantong, C | 1 |
| Supornsilpchai, W | 1 |
| Thongtan, T | 1 |
| Reuangwechvorachai, P | 1 |
| Maneesri-le Grand, S | 1 |
| Barnes, NP | 3 |
| Richer, L | 1 |
| Billinghurst, L | 1 |
| Linsdell, MA | 1 |
| Russell, K | 1 |
| Vandermeer, B | 1 |
| Crumley, ET | 1 |
| Durec, T | 1 |
| Klassen, TP | 1 |
| Hartling, L | 1 |
| Feeney, R | 1 |
| Birru, EM | 1 |
| Abay, Z | 1 |
| Abdelwuhab, M | 1 |
| Basazn, A | 1 |
| Sirak, B | 1 |
| Teni, FS | 1 |
| Dass, K | 1 |
| Bose, S | 1 |
| Ditto, AM | 1 |
| Tan, RY | 1 |
| Markus, HS | 1 |
| Freitag, F | 1 |
| Diamond, M | 1 |
| Diamond, S | 2 |
| Janssen, I | 1 |
| Rodgers, A | 1 |
| Skobieranda, F | 1 |
| Ducros, A | 2 |
| Hofmann, R | 1 |
| Pfaffenrath, V | 4 |
| Pageler, L | 2 |
| Peil, H | 3 |
| Aicher, B | 3 |
| Alzoubi, KH | 1 |
| Mhaidat, N | 1 |
| Azzam, SA | 1 |
| Khader, Y | 1 |
| Salem, S | 1 |
| Issaifan, H | 1 |
| Haddadin, R | 1 |
| James, EK | 1 |
| Vordenbäumen, S | 1 |
| Groiss, SJ | 1 |
| Dihné, M | 1 |
| Cuvellier, JC | 3 |
| Donnet, A | 1 |
| Guégan-Massardier, E | 1 |
| Nachit-Ouinekh, F | 1 |
| Parain, D | 1 |
| Vallée, L | 3 |
| Haag, G | 2 |
| DeLeon, D | 1 |
| Douglas, C | 1 |
| Schwiebert, P | 1 |
| Prior, MJ | 1 |
| Codispoti, JR | 1 |
| Fu, M | 1 |
| Manzano, S | 1 |
| Doyon-Trottier, E | 1 |
| Bailey, B | 1 |
| McQuay, HJ | 1 |
| Shrikanth, V | 1 |
| Vanderheiden, A | 1 |
| Simha, V | 1 |
| Hewitt, DJ | 1 |
| Martin, V | 1 |
| Brandes, J | 1 |
| Ceesay, P | 1 |
| Gottwald, R | 1 |
| Schaefer, E | 1 |
| Lines, C | 1 |
| Ho, TW | 1 |
| Salazar, G | 1 |
| Fragoso, M | 1 |
| Vergez, L | 1 |
| Sergio, P | 1 |
| Cuello, D | 1 |
| Forcelini, CM | 1 |
| Dantas, DC | 1 |
| Luz, C | 1 |
| Santin, R | 1 |
| Stein, AT | 1 |
| Barros, HM | 1 |
| Barea, LM | 1 |
| O'Brien, HL | 1 |
| Kabbouche, MA | 1 |
| Hershey, AD | 1 |
| Öztürk, V | 1 |
| Ertaş, M | 1 |
| Baykan, B | 1 |
| Sirin, H | 1 |
| Özge, A | 1 |
| Mehuys, E | 1 |
| Paemeleire, K | 1 |
| Van Hees, T | 1 |
| Christiaens, T | 1 |
| Van Bortel, L | 1 |
| Van Tongelen, I | 1 |
| Philippe, G | 1 |
| Prévôt, ML | 1 |
| Evrard, B | 1 |
| Piette, M | 1 |
| De Bolle, L | 1 |
| Remon, JP | 1 |
| Boussery, K | 1 |
| Bennadji, B | 1 |
| Desramé, J | 1 |
| de Parades, V | 1 |
| Pini, LA | 1 |
| Guerzoni, S | 1 |
| Cainazzo, M | 1 |
| Ciccarese, M | 1 |
| Prudenzano, MP | 1 |
| Livrea, P | 1 |
| Di, W | 1 |
| Zhu, Y | 1 |
| Tao, Y | 1 |
| Qi, W | 1 |
| Luo, N | 1 |
| Yi, C | 1 |
| Miao, J | 1 |
| Zhang, X | 1 |
| Fox, AW | 1 |
| Sultan, MA | 1 |
| Maher, HM | 1 |
| Alzoman, NZ | 1 |
| Alshehri, MM | 1 |
| Rizk, MS | 1 |
| Elshahed, MS | 1 |
| Olah, IV | 1 |
| Limmroth, V | 2 |
| Rollins, G | 1 |
| Burk, CT | 1 |
| Gilderman, A | 1 |
| Salas, J | 1 |
| Berenbeim, D | 1 |
| Nichol, MB | 1 |
| KRISCHEK, J | 1 |
| Allais, G | 1 |
| Bosio, A | 1 |
| Mana, O | 1 |
| Airola, G | 1 |
| Ciochetto, D | 1 |
| Terzi, MG | 1 |
| De Lorenzo, C | 1 |
| Quirico, PE | 1 |
| Benedetto, C | 1 |
| Morillo, LE | 1 |
| Alarcon, F | 1 |
| Aranaga, N | 1 |
| Aulet, S | 1 |
| Chapman, E | 1 |
| Conterno, L | 1 |
| Estevez, E | 1 |
| Garcia-Pedroza, F | 1 |
| Garrido, J | 1 |
| Macias-Islas, M | 1 |
| Monzillo, P | 1 |
| Nunez, L | 1 |
| Plascencia, N | 1 |
| Rodriguez, C | 1 |
| Takeuchi, Y | 1 |
| Joriot, S | 2 |
| Auvin, S | 2 |
| Lewis, DW | 1 |
| Winner, P | 1 |
| Wasiewski, W | 1 |
| Damen, L | 1 |
| Bruijn, JK | 1 |
| Verhagen, AP | 1 |
| Berger, MY | 1 |
| Passchier, J | 1 |
| Koes, BW | 1 |
| Loder, E | 1 |
| Taylor, K | 1 |
| Almas, M | 1 |
| Hilliard, B | 1 |
| Silberstein, SD | 4 |
| Saper, JR | 3 |
| Elkind, AH | 1 |
| Smith, TR | 2 |
| Gallagher, RM | 2 |
| Battikha, JP | 3 |
| Hoffman, H | 1 |
| Baggish, J | 1 |
| Leinisch, E | 1 |
| Evers, S | 2 |
| Kaempfe, N | 1 |
| Kraemer, C | 1 |
| Sostak, P | 1 |
| Jürgens, T | 1 |
| Straube, A | 1 |
| May, A | 1 |
| Blumenthal, HJ | 1 |
| Diamond, ML | 1 |
| Wenzel, RG | 1 |
| Ryan, RE | 3 |
| Lucas, C | 2 |
| Géraud, G | 2 |
| Valade, D | 2 |
| Chautard, MH | 1 |
| Malik, SN | 1 |
| Hopkins, M | 1 |
| Young, WB | 1 |
| Katsarava, Z | 1 |
| Derosier, FJ | 1 |
| Kori, SH | 1 |
| Lenaerts, ME | 1 |
| Couch, JR | 1 |
| Silver, S | 1 |
| Gano, D | 1 |
| Gerretsen, P | 1 |
| Radat, F | 1 |
| Vives, E | 1 |
| Joubert, JM | 2 |
| Mekies, C | 1 |
| Peatfield, RC | 1 |
| Petty, RG | 1 |
| Rose, FC | 1 |
| Pearce, I | 1 |
| Frank, GJ | 1 |
| Pearce, JM | 1 |
| Carasso, RL | 1 |
| Yehuda, S | 1 |
| Million, R | 1 |
| Finlay, BR | 1 |
| Whittington, JR | 1 |
| Wilkinson, M | 6 |
| Tokola, RA | 2 |
| Neuvonen, PJ | 1 |
| Tfelt-Hansen, P | 3 |
| Jensen, K | 1 |
| Vendsborg, P | 1 |
| Lauritzen, M | 1 |
| Olesen, J | 5 |
| Blau, JN | 1 |
| Behan, P | 1 |
| Aebelholt-Krabbe, A | 1 |
| Melgaard, B | 1 |
| Veilis, B | 2 |
| Jones, A | 1 |
| Harrop, C | 1 |
| Gómez Barrado, JJ | 1 |
| Turégano Albarrán, S | 1 |
| García Rubira, JC | 1 |
| Hidalgo Urbano, R | 1 |
| Rodríguez Revuelta, M | 1 |
| Pérez Leal, I | 1 |
| García Martínez, JT | 1 |
| González López, M | 1 |
| Cruz Fernández, JM | 1 |
| Delonca, O | 1 |
| Barbe, S | 1 |
| Cassan, P | 1 |
| Pariente, EA | 1 |
| George, S | 1 |
| Vannozi, Z | 1 |
| Koehler, PJ | 1 |
| Mulder, LJ | 1 |
| Boureau, F | 1 |
| Lasserre, V | 1 |
| Prum, B | 1 |
| Delecoeuillerie, G | 1 |
| Hoffman, LM | 1 |
| Van Gossum, A | 1 |
| Zalcman, M | 1 |
| Adler, M | 1 |
| Peny, MO | 1 |
| Houben, JJ | 1 |
| Cremer, M | 1 |
| Hoernecke, R | 1 |
| Doenicke, A | 1 |
| MacGregor, EA | 1 |
| Bancroft, K | 1 |
| Catheline, JM | 1 |
| Guiberteau/Canfrere, V | 1 |
| Zarka, O | 1 |
| Le Borgne, J | 1 |
| Lehur, PA | 1 |
| Graf, WD | 1 |
| Riback, PS | 1 |
| Chrubasik, S | 1 |
| Chrubasik, J | 1 |
| Wiedemann, M | 1 |
| de Lima, VM | 1 |
| Hanke, W | 1 |
| Schwarz, N | 1 |
| Ham Pong, A | 1 |
| Hämäläinen, ML | 1 |
| Hoppu, K | 1 |
| Valkeila, E | 1 |
| Santavuori, P | 1 |
| Karabetsos, A | 2 |
| Karachalios, G | 1 |
| Bourlinou, P | 1 |
| Reppa, A | 1 |
| Koutri, R | 1 |
| Fotiadou, A | 2 |
| Joseph, R | 1 |
| Iñiguez, C | 1 |
| Larrodé, P | 1 |
| Mauri, JA | 1 |
| Morales, F | 1 |
| Alam, Z | 1 |
| Coombes, N | 1 |
| Waring, RH | 1 |
| Williams, AC | 1 |
| Steventon, GB | 1 |
| Rolan, P | 1 |
| Amelin, AV | 1 |
| Sorokoumov, VA | 1 |
| Strong, FC | 1 |
| Seaber, EJ | 1 |
| Ridout, G | 1 |
| Layton, G | 1 |
| Posner, J | 1 |
| Peck, RW | 1 |
| Stewart, WF | 2 |
| Saper, J | 1 |
| Silberstein, S | 1 |
| Sheftell, F | 1 |
| Higelin, F | 1 |
| Annoni, JM | 1 |
| Rehm, M | 1 |
| Kwon, SJ | 1 |
| Lee, CW | 1 |
| Maizels, M | 1 |
| Armellino, JJ | 2 |
| Hoffman, HD | 2 |
| Hamelsky, SW | 2 |
| Couch, J | 1 |
| Blumenthal, H | 1 |
| Noth, J | 1 |
| Capodieci, C | 1 |
| Guala, A | 1 |
| Licardi, G | 1 |
| Peretti, M | 1 |
| Rankin, LM | 1 |
| Bruhl, M | 1 |
| Dowson, A | 1 |
| Ball, K | 1 |
| Haworth, D | 1 |
| Evans, RW | 1 |
| Freitag, FG | 1 |
| Cady, R | 1 |
| DiSerio, F | 1 |
| Elkind, A | 1 |
| Klapper, JA | 1 |
| Rapoport, AM | 1 |
| Sadowsky, C | 1 |
| Pothmann, R | 1 |
| Uberall, M | 1 |
| Naumann, E | 1 |
| Gerber, WD | 1 |
| Kolar, KR | 1 |
| Fisher, W | 1 |
| Gordon, V | 1 |
| Landy, S | 1 |
| Richardson, M | 1 |
| O'Quinn, S | 1 |
| Calero Muñoz, S | 1 |
| Fariñas Balaguer, O | 1 |
| Nieto Márquez, L | 1 |
| Cobo Guerrero, S | 1 |
| Fozard, JR | 1 |
| Krabbe, AA | 1 |
| Schütz, E | 1 |
| Critchley, EM | 1 |
| Somerville, BW | 1 |
| Merrington, DM | 1 |
| Philipp, M | 1 |
| Pradalier, A | 1 |
| Vincent, D | 1 |
| Karachalios, GN | 1 |
| Chrisikos, N | 1 |
| Kehagioglou, K | 1 |
| Becker, A | 1 |
| Berner, G | 1 |
| Leuschner, F | 1 |
| Vögtle-Junkert, U | 1 |
| Larsen, BH | 1 |
| Christiansen, LV | 2 |
| Andersen, B | 1 |
| Persaud, N | 1 |
| Johnson, ES | 1 |
| Merrington, D | 1 |
| Oliver, W | 1 |
| Nørrelund, N | 1 |
| Plantener, S | 1 |
| Uzogara, E | 1 |
| Sheehan, DV | 1 |
| Manschreck, TC | 1 |
| Jones, KJ | 1 |
| Dexter, SL | 1 |
| Graham, AN | 1 |
| Johnston, ES | 1 |
| Ratcliffe, DM | 1 |
| Wilkinson, MI | 1 |
| Rose, AJ | 1 |
| Wineinger, MA | 1 |
| Basford, JR | 1 |
| Scopa, J | 1 |
| Jorgensen, PB | 2 |
| Foster, JB | 2 |
| Weightman, D | 1 |
| Messerich, J | 1 |
| Matts, SG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Single Center Study on the Sustained Effect of OnabotulinumtoxinA (BOTOX®) vs. IncobotulinumtoxinA (XEOMIN®) Botulinum Toxin in Adults With Chronic Migraine[NCT05598723] | Phase 3 | 128 participants (Anticipated) | Interventional | 2023-02-24 | Recruiting | ||
| Acute Headache Treatment in Pregnancy: Improvement in Pain Scores With Occipital Nerve Block vs PO Acetaminophen With Caffeine A Randomized Controlled Trial[NCT03951649] | Phase 4 | 62 participants (Actual) | Interventional | 2020-02-10 | Completed | ||
| Comparison of Efficacy Between Combination of Amitriptyline-propranolol and Pizotifen for Migraine Prophylaxis: A Single-blind Randomized Controlled Trial[NCT06158230] | Phase 2 | 140 participants (Actual) | Interventional | 2023-03-19 | Active, not recruiting | ||
| A Randomized Double-blind Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache[NCT03472872] | Phase 4 | 500 participants (Actual) | Interventional | 2017-09-05 | Terminated (stopped due to no longer recruiting or studying) | ||
| A Pilot Trial of Galcanezumab for Vestibular Migraine[NCT04417361] | Phase 2 | 50 participants (Anticipated) | Interventional | 2020-09-18 | Recruiting | ||
| Study of Comparing Dexketoprofen to Placebo in Migraine Attack[NCT02159547] | Phase 4 | 224 participants (Actual) | Interventional | 2014-05-31 | Completed | ||
| The Comparison of the Effectiveness of Intravenous Dexketoprofen and Paracetamol in the Treatment of Headache Caused by Acute Migraine Attack in Emergency Service[NCT01730326] | Phase 4 | 200 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| A Phase IIa Randomized, Double-Blind, Parallel-Group, Placebo and Active-Controlled, Clinical Trial to Study the Efficacy and Safety of MK0974 Co-administered With Ibuprofen or Acetaminophen in Patients With Migraine With or Without Aura[NCT00758836] | Phase 2 | 683 participants (Actual) | Interventional | 2008-12-03 | Completed | ||
| Evaluation of Efficacy and Safety of add-on Alpha-lipoic Acid on Migraine Prophylaxis in Adolescent Population: A Randomized Controlled Trial[NCT04064814] | Phase 4 | 60 participants (Actual) | Interventional | 2019-09-14 | Completed | ||
| A Randomized Double Blinded Study Comparing Use of Prochlorperazine Versus Prochlorperazine and Ketorolac in the Treatment of Pediatric Migraine in the Emergency Department[NCT01534806] | Phase 4 | 0 participants (Actual) | Interventional | 2012-01-31 | Withdrawn (stopped due to Drug is backordered;) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT03951649)
Timeframe: 7 days
| Intervention | days (Median) |
|---|---|
| Occipital Nerve Block | 6 |
| Oral Acetaminophen/Caffeine Group | 1 |
(NCT03951649)
Timeframe: 28 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 9 |
| Oral Acetaminophen/Caffeine Group | 4 |
(NCT03951649)
Timeframe: 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 7 |
| Oral Acetaminophen/Caffeine Group | 2 |
Other: Pain at injection site (NCT03951649)
Timeframe: 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 0 |
| Oral Acetaminophen/Caffeine Group | 2 |
(NCT03951649)
Timeframe: 7 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 0 |
| Oral Acetaminophen/Caffeine Group | 0 |
(NCT03951649)
Timeframe: 4 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 9 |
| Oral Acetaminophen/Caffeine Group | 14 |
(NCT03951649)
Timeframe: 5 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 4 |
| Oral Acetaminophen/Caffeine Group | 2 |
Emergency department for treatment of headache since treatment asked at 28 day follow up (NCT03951649)
Timeframe: 28 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 5 |
| Oral Acetaminophen/Caffeine Group | 1 |
(NCT03951649)
Timeframe: 120 min
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 5 |
| Oral Acetaminophen/Caffeine Group | 5 |
Based on guidelines from the International Headache Society the primary outcome is the portion of women who experience resolution of headache or improvement of headache to mild range (VRS ≤ 3) at 2 hours following treatment with Occipital nerve block as compared to acetaminophen/caffeine cocktail. (NCT03951649)
Timeframe: 60-300 min
| Intervention | Participants (Count of Participants) |
|---|---|
| Occipital Nerve Block | 20 |
| Oral Acetaminophen/Caffeine Group | 16 |
"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 60 min
| Intervention | score on a scale (Median) |
|---|---|
| Occipital Nerve Block | 6 |
| Oral Acetaminophen/Caffeine Group | 3 |
"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 180min
| Intervention | score on a scale (Median) |
|---|---|
| Occipital Nerve Block | 6 |
| Oral Acetaminophen/Caffeine Group | 4 |
"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 2 hrs
| Intervention | score on a scale (Median) |
|---|---|
| Occipital Nerve Block | 6.0 |
| Oral Acetaminophen/Caffeine Group | 6.5 |
The adverse effects is being recorded to the study form after the study drugs are administered at the 45th minutes. (NCT02159547)
Timeframe: 45th minutes
| Intervention | participants (Number) |
|---|---|
| Dexketoprofen | 0 |
| Normal Slaline | 0 |
Change from baseline in Visual Analogue Scale, 100 mm, at 45th minutes. Visual Analogue Scale is measurement tool scoring tool between 0 (no pain) and 100 mm (worst pain). Minimum clinically significant change in pain score is 13 or 16 mm. (NCT02159547)
Timeframe: 45 minutes
| Intervention | units on a scale (Median) |
|---|---|
| Dexketoprofen | 55 |
| Normal Slaline | 30 |
An adverse event is any unfavorable and unintended change in the structure, function, or chemistry of the body whether or not considered related to the study treatment. (NCT00758836)
Timeframe: Up to 14 days post-dose
| Intervention | participants (Number) |
|---|---|
| Placebo | 31 |
| Telcagepant 280 mg +Ibuprofen 400 mg | 46 |
| Telcagepant 280 mg +APAP 1000 mg | 46 |
| Telcagepant 280 mg | 37 |
An adverse event is any unfavorable and unintended change in the structure, function, or chemistry of the body whether or not considered related to the study treatment. (NCT00758836)
Timeframe: Up to 48 hours post-dose
| Intervention | Participants (Number) |
|---|---|
| Placebo | 27 |
| Telcagepant 280 mg +Ibuprofen 400 mg | 44 |
| Telcagepant 280 mg +APAP 1000 mg | 42 |
| Telcagepant 280 mg | 34 |
Pain severity was rated by the participants in a paper diary by grade; Grade 0 (no pain), Grade 1 (mild pain), Grade 2 (moderate pain), and Grade 3 (severe pain). Pain freedom was defined as a reduction in pain severity from moderate to severe migraine headache (Grade 2 or 3) to no pain (Grade 0). (NCT00758836)
Timeframe: 2 hours post-dose
| Intervention | Percentage of Participants (Number) |
|---|---|
| Placebo | 10.9 |
| Telcagepant 280 mg +Ibuprofen 400 mg | 35.2 |
| Telcagepant 280 mg +APAP 1000 mg | 38.3 |
| Telcagepant 280 mg | 31.2 |
Pain severity was rated by the participants in a paper diary by grade; Grade 0 (no pain), Grade 1 (mild pain), Grade 2 (moderate pain), and Grade 3 (severe pain). Pain relief was defined as a reduction in pain severity from moderate to severe migraine headache (Grade 2 or 3) to mild or none (Grade 1 or 0). (NCT00758836)
Timeframe: 2 hours post-dose
| Intervention | Percentage of Participants (Number) |
|---|---|
| Placebo | 30.6 |
| Telcagepant 280 mg +Ibuprofen 400 mg | 71.0 |
| Telcagepant 280 mg +APAP 1000 mg | 69.9 |
| Telcagepant 280 mg | 65.2 |
43 reviews available for acetaminophen and Migraine Disorders
| Article | Year |
|---|---|
Aspirin, paracetamol (acetaminophen) and caffeine for the treatment of acute migraine attacks: A systemic review and meta-analysis of randomized placebo-controlled trials.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Humans; Migraine Disorders; Randomized C | 2022 |
Second-line interventions for migraine in the emergency department: A narrative review.
Topics: Acetaminophen; Administration, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Emergency Servi | 2021 |
Treatment of acute migraine attacks in children with analgesics on the World Health Organization Essential Medicines List: A systematic review and GRADE evidence synthesis.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Child; Humans; Ibuprofen; Migraine Disorders | 2018 |
Caffeine in the management of patients with headache.
Topics: Abdominal Pain; Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Central Nervous System Stimulan | 2017 |
Migraine Treatment: Current Acute Medications and Their Potential Mechanisms of Action.
Topics: Acetaminophen; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dopamine Antago | 2018 |
Melatonin for preventing primary headache: A systematic review.
Topics: Acetaminophen; Analgesics; Aspirin; Central Nervous System Depressants; Humans; Melatonin; Migraine | 2018 |
Acute Treatment of Migraine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Electric Stimulati | 2018 |
Pharmacotherapy for acute migraines in children and adolescents.
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Migraine D | 2019 |
Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Antiemetics; Drug Therapy, Combinatio | 2013 |
Primary headache disorders.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Chronic Disease; Cluster Headache; Cycloox | 2013 |
Pediatric migraine: abortive management in the emergency department.
Topics: Acetaminophen; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Dopamin | 2014 |
Oral triptans in children and adolescents: an update.
Topics: Acetaminophen; Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Dos | 2015 |
Pharmacological treatment of migraine during pregnancy and breastfeeding.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; | 2015 |
Migraine headache in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Mig | 2015 |
[Update on Current Care Guideline: Migraine].
Topics: Acetaminophen; Adrenergic beta-Antagonists; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opi | 2015 |
Drugs for the acute treatment of migraine in children and adolescents.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Dihydroergotamine; Humans; Ibuprofen; Mi | 2016 |
Emergency treatment of migraine.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Emergencie | 2008 |
Migraine headache in children.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Migraine Disorders; Sexual Ma | 2009 |
[Self-medication of primary headaches].
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diclof | 2009 |
Question: What are the best pharmacological options for treating the symptoms of migraine headaches in children?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Decision Making; Humans; Ibuprofen; Migraine Disorde | 2010 |
Myth: Ibuprofen is superior to acetaminophen for the treatment of benign headaches in children and adults.
Topics: Acetaminophen; Adolescent; Adult; Altitude Sickness; Analgesics, Non-Narcotic; Child; Headache; Huma | 2010 |
Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiemetics; Drug Therapy, Combination; Humans; Hype | 2010 |
Migraine headache in children.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Migraine Disorders; Sexual Ma | 2011 |
Treating pediatric migraine: an expert opinion.
Topics: Acetaminophen; Analgesics; Behavior Therapy; Child; Humans; Ibuprofen; Migraine Disorders | 2012 |
Analgesics.
Topics: Acetaminophen; Administration, Intranasal; Administration, Oral; Analgesics, Non-Narcotic; Analgesic | 2001 |
[Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies].
Topics: Abnormalities, Drug-Induced; Acetaminophen; Acupuncture Points; Acupuncture Therapy; Adult; Analgesi | 2003 |
Headache in children and adolescents: conventional and unconventional approaches to treatment.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Headache Disorders; Humans; Migraine Dis | 2004 |
[Pharmacologic treatment of acute migraine attack in children].
Topics: Acetaminophen; Acute Disease; Administration, Intranasal; Administration, Oral; Adolescent; Age Fact | 2005 |
The placebo responder rate in children and adolescents.
Topics: Acetaminophen; Acute Disease; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Clinical T | 2005 |
Symptomatic treatment of migraine in children: a systematic review of medication trials.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Controlled Clinical Tr | 2005 |
[Self-medication of migraine and headache].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; | 2006 |
[Acute and chronic headaches].
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2006 |
Medication overuse headache.
Topics: Acetaminophen; Adult; Analgesics; Drug Combinations; Female; Headache; Humans; Hydrocodone; Migraine | 2007 |
Acute treatment of paediatric migraine: a meta-analysis of efficacy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 2008 |
Pharmacologic treatment of recurrent pediatric headache.
Topics: Acetaminophen; Adolescent; Adrenal Cortex Hormones; Analgesics; Aspirin; Child; Child, Preschool; Er | 1995 |
Potential drug interactions with the novel antimigraine compound zolmitriptan (Zomig, 311C90).
Topics: Acetaminophen; Adolescent; Adult; Drug Interactions; Drug Therapy, Combination; Ergotamine; Female; | 1997 |
Medical treatment of migraine: from mechanisms of action to contraindications.
Topics: Acetaminophen; Adrenergic beta-Antagonists; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Asp | 1998 |
Migraine in pregnancy: what are the safest treatment options?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Female; Humans; Migraine Disorders; Pregnancy; Pre | 1998 |
[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)].
Topics: Acetaminophen; Adrenergic beta-Antagonists; Age Factors; Analgesics, Non-Narcotic; Biofeedback, Psyc | 2002 |
"Nurse, my head hurts": a review of childhood headaches.
Topics: Acetaminophen; Adolescent; Age Factors; Analgesics, Non-Narcotic; Child; Child, Preschool; Emergenci | 2001 |
[The latest in headache treatment].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Angiotensin-Converting | 2002 |
The animal pharmacology of drugs used in the treatment of migraine.
Topics: Acetaminophen; Adrenergic alpha-Antagonists; Analgesics; Animals; Aspirin; Caffeine; Clonidine; Cypr | 1975 |
[Migraine and non-steroidal anti-inflammatory agents].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic | 1992 |
60 trials available for acetaminophen and Migraine Disorders
| Article | Year |
|---|---|
The Efficacy of Topical Basil Essential Oil on Relieving Migraine Headaches: A Randomized Triple-Blind Study.
Topics: Acetaminophen; Administration, Topical; Adolescent; Adult; Analgesics, Non-Narcotic; Double-Blind Me | 2020 |
Paracetamol versus Ibuprofen for the Acute Treatment of Migraine Headache in Children: A Blinded Randomized Controlled Trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Double-Blind Method; Female; Humans; Ibuprofen; Indi | 2020 |
Treatment of withdrawal headache in patients with medication overuse headache: a pilot study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Drug Therapy, Combination; Female; Glucocorticoids; | 2017 |
Efficacy of amitriptyline, pizotifen and propranolol in the prevention of migraine.
Topics: Acetaminophen; Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Antiemetics; Child; Dompe | 2013 |
Effects of acetaminophen and ibuprofen in children with migraine receiving preventive treatment with magnesium.
Topics: Acetaminophen; Adolescent; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Ibupr | 2014 |
Flunarizine in the prophylaxis of migrainous vertigo: a randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Betahistine; Calcium Channel Blockers; Disorders of Excessiv | 2014 |
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2014 |
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2014 |
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2014 |
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2014 |
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2014 |
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2014 |
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2014 |
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2014 |
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2014 |
Results of a multicenter, double-blind, randomized, parallel-group, placebo-controlled, single-dose study comparing the fixed combination of acetaminophen, acetylsalicylic acid, and caffeine with ibuprofen for acute treatment of patients with severe migra
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination; | 2014 |
Efficacy of intravenous propacetamol hydrochloride in the treatment of an acute attack of migraine.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Female; Follow-Up | 2014 |
Clinicopharmacological comparative study of rizatriptan versus conventional therapy in migraine.
Topics: Acetaminophen; Adolescent; Adult; Aged; Alprazolam; Analgesics, Non-Narcotic; Female; Flunarizine; H | 2014 |
Efficacy and tolerability of coadministration of rizatriptan and acetaminophen vs rizatriptan or acetaminophen alone for acute migraine treatment.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Drug Thera | 2008 |
Headache classification by history has only limited predictive value for headache episodes treated in controlled trials with OTC analgesics.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Caffeine; Double-Blind Me | 2009 |
Treatment of primary headache in children: a multicenter hospital-based study in France.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 2009 |
A randomized, placebo-controlled trial of acetaminophen for treatment of migraine headache.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; | 2010 |
Randomized controlled study of telcagepant plus ibuprofen or acetaminophen in migraine.
Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Calcitonin Gene | 2011 |
Randomized controlled study of telcagepant plus ibuprofen or acetaminophen in migraine.
Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Calcitonin Gene | 2011 |
Randomized controlled study of telcagepant plus ibuprofen or acetaminophen in migraine.
Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Calcitonin Gene | 2011 |
Randomized controlled study of telcagepant plus ibuprofen or acetaminophen in migraine.
Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Calcitonin Gene | 2011 |
Metoclopramide as an analgesic in severe migraine attacks: an open, single-blind, parallel control study.
Topics: Acetaminophen; Adult; Analgesics; Female; Humans; Male; Metoclopramide; Migraine Disorders; Single-B | 2011 |
The efficacy and tolerability of a fixed combination of acetylsalicylic acid, paracetamol, and caffeine in patients with severe headache: a post-hoc subgroup analysis from a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel g
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 2011 |
Efficacy and safety of 400 and 800 mg etodolac vs. 1,000 mg paracetamol in acute treatment of migraine: a randomized, double-blind, crossover, multicenter, phase III clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Cross-Over Studies; Double-Blind Method; Etodola | 2013 |
Comparison of tolerability and efficacy of a combination of paracetamol + caffeine and sumatriptan in the treatment of migraine attack: a randomized, double-blind, double-dummy, cross-over study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Caffeine; Double-Blind Method; Drug Therapy, Combina | 2012 |
Efficacy, end points and eventualities: sumatriptan/naproxen versus butalbital/paracetamol/caffeine in the treatment of migraine.
Topics: Acetaminophen; Barbiturates; Caffeine; Double-Blind Method; Drug Combinations; Drug Therapy, Combina | 2012 |
Eletriptan treatment of migraine in patients switching from barbiturate-containing analgesics: results from a multiple-attack study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Barbiturates; Caffeine; Drug Combinations; Fe | 2005 |
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non- | 2005 |
Evaluation of the efficacy of intravenous acetaminophen in the treatment of acute migraine attacks: a double-blind, placebo-controlled parallel group multicenter study.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesics, Non-Narcotic; Anesthesia, Intravenous; Demogr | 2005 |
The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group st
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; | 2005 |
Acetaminophen, aspirin, and caffeine in combination versus ibuprofen for acute migraine: results from a multicenter, double-blind, randomized, parallel-group, single-dose, placebo-controlled study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ca | 2006 |
Double blind comparison of mefenamic acid and acetaminophen (paracetamol) in migraine.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mal | 1983 |
Ibuprofen compared with paracetamol in migraine.
Topics: Acetaminophen; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ibuprofen; Male | 1983 |
The prevention and treatment of migraine with an analgesic combination.
Topics: Acetaminophen; Adult; Clinical Trials as Topic; Codeine; Drug Combinations; Female; Humans; Male; Mi | 1984 |
Clinical trial of flupirtine maleate in patients with migraine.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aminopyridines; Clinical Trials as Top | 1984 |
Chlormezanone in the treatment of migraine attacks: a double blind comparison with diazepam and placebo.
Topics: Acetaminophen; Chlormezanone; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Therapy, | 1982 |
Double-blind comparison of an acetaminophen 400 mg-codeine 25 mg combination versus aspirin 1000 mg and placebo in acute migraine attack.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Codeine; Double-Blind Method; Drug Therapy, Combina | 1994 |
[Treatment of migraine attacks: combination of dihydroergotamine tartrate and paracetamol in comparison with individual drugs and placebo].
Topics: Acetaminophen; Adolescent; Adult; Aged; Dihydroergotamine; Double-Blind Method; Drug Therapy, Combin | 1993 |
Domperidone plus paracetamol in the treatment of migraine.
Topics: Acetaminophen; Adolescent; Adult; Aged; Domperidone; Double-Blind Method; Drug Combinations; Female; | 1993 |
Ibuprofen or acetaminophen for the acute treatment of migraine in children: a double-blind, randomized, placebo-controlled, crossover study.
Topics: Acetaminophen; Administration, Oral; Adolescent; Child; Child, Preschool; Cross-Over Studies; Double | 1997 |
Ketoprofen versus paracetamol in the treatment of acute migraine.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 1997 |
It may be the caffeine in Extra Strength Excedrin that is effective for migraine.
Topics: Acetaminophen; Adjuvants, Pharmaceutic; Analgesics; Aspirin; Caffeine; Dose-Response Relationship, D | 1997 |
The novel anti-migraine compound zolmitriptan (Zomig 311C90) has no clinically significant interactions with paracetamol or metoclopramide.
Topics: Acetaminophen; Adult; Blood Pressure; Drug Interactions; Female; Humans; Male; Metoclopramide; Migra | 1997 |
Efficacy and safety of acetaminophen, aspirin, and caffeine in alleviating migraine headache pain: three double-blind, randomized, placebo-controlled trials.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination; | 1998 |
Treatment of menstruation-associated migraine with the nonprescription combination of acetaminophen, aspirin, and caffeine: results from three randomized, placebo-controlled studies.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammato | 1999 |
Treatment of severe, disabling migraine attacks in an over-the-counter population of migraine sufferers: results from three randomized, placebo-controlled studies of the combination of acetaminophen, aspirin, and caffeine.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Caffeine; Double-Blind Method; D | 1999 |
Comparison of a fixed combination of domperidone and paracetamol (Domperamol) with sumatriptan 50 mg in moderate to severe migraine: a randomised UK primary care study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cost-Benefit Analysis; Cross-Over Studies; Domperido | 2000 |
Comparative study of a combination of isometheptene mucate, dichloralphenazone with acetaminophen and sumatriptan succinate in the treatment of migraine.
Topics: Acetaminophen; Adult; Analgesics; Antipyrine; Capsules; Chloral Hydrate; Double-Blind Method; Drug C | 2001 |
Treatment of migraine attacks with an analgesic combination (Mersyndol).
Topics: Acetaminophen; Acute Disease; Caffeine; Clinical Trials as Topic; Codeine; Doxylamine; Drug Combinat | 1976 |
Comments on Migraleve trial reports.
Topics: Acetaminophen; Analgesics; Body Weight; Clinical Trials as Topic; Codeine; Drug Combinations; Humans | 1975 |
[Therapy of migraine. Clinical experience with Migraeflux, a new migraine drug].
Topics: Acetaminophen; Adolescent; Adult; Child; Child, Preschool; Codeine; Dimenhydrinate; Drug Combination | 1977 |
Treatment of migraine with isometheptene, acetaminophen, and dichloralphenazone combination: a double-blind, crossover trial.
Topics: Acetaminophen; Adult; Alkenes; Antipyrine; Chloral Hydrate; Clinical Trials as Topic; Drug Combinati | 1976 |
[Migraine and non-steroidal anti-inflammatory agents].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic | 1992 |
Treatment of acute migraine attack with diclofenac sodium: a double-blind study.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Diclofenac; Double-Blind Method; Female; Huma | 1992 |
Randomized double-blind comparison of tolfenamic acid and paracetamol in migraine.
Topics: Acetaminophen; Adult; Aged; Analgesics; Double-Blind Method; Female; Humans; Male; Middle Aged; Migr | 1990 |
The relative bioavailability of paracetamol and codeine after oral administration of a combination of buclizine, paracetamol and codeine, with or without docusate, and of paracetamol alone in healthy volunteers.
Topics: Acetaminophen; Administration, Oral; Adult; Biological Availability; Clinical Trials as Topic; Codei | 1985 |
[Tolfenamic acid versus paracetamol in migraine attacks. A double-blind study in general practice].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Clinical Trials as Topic; Double-Blind Method; H | 1989 |
The effect of metoclopramide and prochlorperazine on the absorption of effervescent paracetamol in migraine.
Topics: Acetaminophen; Administration, Rectal; Adult; Antiemetics; Female; Humans; Metoclopramide; Middle Ag | 1988 |
A combination drug treatment for acute common migraine.
Topics: Acetaminophen; Adult; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Fem | 1986 |
Double-blind controlled study of paramax in the acute treatment of common and classical migraine.
Topics: Acetaminophen; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Fem | 1985 |
Migraine treated with an antihistamine-analgesic combination.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Codeine; Cyclizine; Ergotamine; Female; | 1973 |
Migraleve in the prophylaxis of migraine.
Topics: Acetaminophen; Adolescent; Adult; Body Weight; Clinical Trials as Topic; Codeine; Drug Combinations; | 1974 |
Comparison of migraleve and buclizine in prophylaxis of migraine.
Topics: Acetaminophen; Analgesics; Body Weight; Clinical Trials as Topic; Codeine; Drug Combinations; Female | 1974 |
Midrid for migraine?
Topics: Acetaminophen; Antipyrine; Chloral Hydrate; Clinical Trials as Topic; Drug Combinations; Humans; Mig | 1972 |
[EMA 3--a phenacetin-free combination with analgesic action].
Topics: Acetaminophen; Adult; Aged; Allyl Compounds; Analgesics; Barbiturates; Caffeine; Clinical Trials as | 1973 |
A study of midrin in the symptomatic relief of migraine headache.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Antipyrine; Capsules; Chloral Hydrate; Clinical Tr | 1974 |
95 other studies available for acetaminophen and Migraine Disorders
| Article | Year |
|---|---|
[Trigeminal evoked potentials in migraine].
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Aspirin; Brain; Cerebr | 1998 |
Migraine abortive treatment in children and adolescents in Israel.
Topics: Acetaminophen; Adolescent; Child; Dipyrone; Female; Headache; Humans; Ibuprofen; Israel; Male; Migra | 2022 |
Predictive models for determining treatment response to nonprescription acute medications in migraine: Results from the American Migraine Prevalence and Prevention Study.
Topics: Acetaminophen; Caffeine; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; Nonprescri | 2022 |
Practice guidelines for the treatment of acute migraine and chronic knee osteoarthritis with paracetamol: an expert appraisal on evolution over time between scientific societies.
Topics: Acetaminophen; Chronic Pain; Humans; Migraine Disorders; Osteoarthritis, Hip; Osteoarthritis, Knee; | 2022 |
Intravenous chlorpromazine for acute paediatric migraine.
Topics: Acetaminophen; Child; Chlorpromazine; Emergency Service, Hospital; Humans; Ibuprofen; Migraine Disor | 2022 |
2022 Taiwan Guidelines for Acute Treatment of Migraine.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin G | 2022 |
Predictors of treatment-response to caffeine combination products, acetaminophen, acetylsalicylic acid (aspirin), and nonsteroidal anti-inflammatory drugs in acute treatment of episodic migraine.
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Female | 2023 |
Paracetamol use prior to and in early pregnancy: Prevalence and patterns among women with and without chronic medical diseases.
Topics: Acetaminophen; Female; Humans; Mental Disorders; Migraine Disorders; Pain Management; Pregnancy; Pre | 2023 |
Prenatal paracetamol exposure and neurodevelopmental outcomes in preschool-aged children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Behavior; Child Behavior Disorders; Child Development | 2020 |
Altered activity in the nucleus raphe magnus underlies cortical hyperexcitability and facilitates trigeminal nociception in a rat model of medication overuse headache.
Topics: Acetaminophen; Action Potentials; Animals; Cerebral Cortex; Disease Models, Animal; Headache Disorde | 2019 |
Multilocular bullous fixed drug eruption elicited by paracetamol and migraine attacks, but not by paracetamol alone.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Blister; Dr | 2020 |
Paracetamol versus Ibuprofen for the Acute Treatment of Migraine Headache in Children: A Blinded Randomized Controlled Trial - Correspondence.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Humans; Ibuprofen; Migraine Disorders | 2021 |
Acetaminophen or Ibuprofen: A Riddle Worth Solving in an Acute Attack of Pediatric Migraine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Humans; Ibuprofen; Migraine Disorders | 2020 |
Diagnosis and Treatment of Headache in a Pediatric Emergency Department.
Topics: Acetaminophen; Adolescent; Child; Emergency Service, Hospital; Female; Headache; Humans; Male; Migra | 2020 |
Polypharmacy and comorbidities during pregnancy in a cohort of women with migraine.
Topics: Acetaminophen; Analgesics, Opioid; Anticonvulsants; Antihypertensive Agents; Comorbidity; Female; Hu | 2021 |
Understanding the migraine treatment landscape prior to the introduction of calcitonin gene-related peptide inhibitors: Results from the Assessment of TolerabiliTy and Effectiveness in MigrAINe Patients using Preventive Treatment (ATTAIN) study.
Topics: Acetaminophen; Adrenergic beta-Antagonists; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agent | 2021 |
Patterns and predictors of analgesic use in pregnancy: a longitudinal drug utilization study with special focus on women with migraine.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Cohort Studies; Drug Substitution; Drug | 2017 |
Serotonin syndrome in patients with headache disorders.
Topics: Acetaminophen; Adult; Amitriptyline; Analgesics; Cluster Headache; Drug Therapy, Combination; Flunar | 2017 |
Prevalence and clinical characteristics of headaches among undergraduate students in three tertiary institutions in Ilorin, Nigeria.
Topics: Acetaminophen; Adolescent; Adult; Chronic Disease; Cross-Sectional Studies; Female; Headache; Humans | 2017 |
Acute Migraine Headache: Treatment Strategies.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Curriculum; Education, Medical, | 2018 |
Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study.
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Diphenhydramine; Drug Therapy, Combination; Female; H | 2019 |
Migraine, tension-type headache, and depression among Saudi female students in Taif University.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anxiety; Comorbidity; Cross-Sectional Studies; Depre | 2019 |
Treatment of acute migraine in the emergency department.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents | 2014 |
Trial registration: must take place before or at the onset of enrolment.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Female | 2014 |
How general practitioners treat migraine in children--evaluation of a headache guideline.
Topics: Acetaminophen; Adolescent; Analgesics; Child; Child, Preschool; Cross-Sectional Studies; Female; Gen | 2014 |
[Footballer's migraine instead of concussion].
Topics: Acetaminophen; Adult; Antiemetics; Brain Concussion; Diagnosis, Differential; Humans; Male; Migraine | 2014 |
[Chemical proctitis due to ergotamine: «not always an ulcerative colitis»].
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Diagnosis, Differ | 2015 |
Up-regulation of calcitonin gene-related peptide in trigeminal ganglion following chronic exposure to paracetamol in a CSD migraine animal model.
Topics: Acetaminophen; Animals; Calcitonin Gene-Related Peptide; Cortical Spreading Depression; Disease Mode | 2015 |
Medication Overuse Headache Due to Butalbital, Acetaminophen, and Caffeine Tablets.
Topics: Acetaminophen; Analgesics; Barbiturates; Caffeine; Drug Combinations; Headache Disorders, Secondary; | 2016 |
Management of headache and associated factors among undergraduate medicine and health science students of University of Gondar, North West Ethiopia.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cross-Sectional Studies; Disease Management; Ethiopi | 2016 |
An unusual case of immediate hypersensitivity reaction to a common medication.
Topics: Acetaminophen; Administration, Oral; Adult; Anaphylaxis; Desensitization, Immunologic; Drug Hypersen | 2016 |
CADASIL: Migraine, Encephalopathy, Stroke and Their Inter-Relationships.
Topics: Acetaminophen; Adult; Age of Onset; Aged; Aged, 80 and over; Analgesics; CADASIL; Codeine; Cross-Sec | 2016 |
More to be said on "Triptans vs other drugs for acute migraine. Are there differences in efficacy?".
Topics: Acetaminophen; Analgesics; Aspirin; Dosage Forms; Humans; Ibuprofen; Migraine Disorders; Randomized | 2009 |
Prevalence of migraine and tension-type headache among adults in Jordan.
Topics: Acetaminophen; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Analgesics; Drug-Relate | 2009 |
Isolated unilateral temporal muscle hypertrophy: a rare cause of hemicranial headache.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Diagnosis, Differential; Female; Functional Laterality; Hum | 2009 |
Spontaneous intracerebral hemorrhage associated with ingestion of isometheptine containing anti-migraine medication.
Topics: Acetaminophen; Adult; Antipyrine; Cerebral Hemorrhage; Chloral Hydrate; Drug Combinations; Emergency | 2011 |
Analysis of leukocytes in medication-overuse headache, chronic migraine, and episodic migraine.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antigens, CD; Cell Count; Female; Headache Disorders | 2011 |
Migraine attacks: paracetamol first.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Clinical Trials as Topic; Humans; Migraine Disorders | 2012 |
[Self-medication of regular headache: a community pharmacy-based survey in Belgium].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 2012 |
Migraine and proctitis: what is the link?
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Caffeine; Central Nervous System | 2013 |
Overuse of paracetamol caffeine aspirin powders affects cerebral glucose metabolism in chronic migraine patients.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Br | 2013 |
Capillary electrophoretic determination of antimigraine formulations containing caffeine, ergotamine, paracetamol and domperidone or metoclopramide.
Topics: Acetaminophen; Caffeine; Domperidone; Drug Combinations; Drug Stability; Electrophoresis, Capillary; | 2013 |
Migraine sufferers are not seeking nor receiving guideline-based care.
Topics: Acetaminophen; Analgesics; Barbiturates; Caffeine; Drug Combinations; Drug Prescriptions; Female; He | 2002 |
The impact of an over-the-counter migraine medication program on quality of life.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Drug Pre | 2003 |
[Migraine therapy with migraine kranit].
Topics: Acetaminophen; Antipyrine; Caffeine; Drug Combinations; Humans; Migraine Disorders; Muscle Relaxants | 1951 |
Clinical characteristics and patterns of medication use of migraneurs in Latin America from 12 cities in 6 countries.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Disabled Pe | 2005 |
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial--a comment.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; | 2006 |
A comment on acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; | 2006 |
[Medical treatment of migraine attacks in the child].
Topics: Acetaminophen; Age Factors; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Ergot Alkalo | 2006 |
Recognition and therapeutic management of migraine in 2004, in France: results of FRAMIG 3, a French nationwide population-based survey.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Comorbidity; Disability Evaluati | 2006 |
Acute migraine treatment: patterns of use and satisfaction in a clinical population.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffein | 2006 |
Is a combination of tramadol and acetaminophen effective for the treatment of acute migraine pain?
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Combinations; Human | 2006 |
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial--a comment.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Enzyme Inhibitors; Humans; Migraine Diso | 2007 |
SMILE: first observational prospective cohort study of migraine in primary care in France. Description of methods and study population.
Topics: Acetaminophen; Adaptation, Psychological; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, | 2008 |
Ibuprofen: new indication. Migraine attacks: don't begin with 400 mg!
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Rela | 2007 |
Treatment of the acute migraine attack--current status.
Topics: Acetaminophen; Aspirin; Drug Therapy, Combination; Ergotamine; Ergotamines; Humans; Metoclopramide; | 1983 |
Effect of migraine attacks on paracetamol absorption.
Topics: Acetaminophen; Adult; Female; Humans; Intestinal Absorption; Kinetics; Middle Aged; Migraine Disorde | 1984 |
A plain man's guide to the management of migraine.
Topics: Acetaminophen; Aspirin; Ergotamine; Headache; Humans; Metoclopramide; Migraine Disorders; Sleep | 1982 |
Migraine: a rational approach to therapy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Child; Drug Combinations; Female; Humans; Male; Metocloprami | 1982 |
A double blind study of metoclopramide in the treatment of migraine attacks.
Topics: Acetaminophen; Adolescent; Adult; Aged; Diazepam; Double-Blind Method; Drug Therapy, Combination; Fe | 1980 |
Paracetamol (acetaminophen) versus acetylsalicylic acid in migraine.
Topics: Acetaminophen; Acute Disease; Aspirin; Diazepam; Drug Evaluation; Drug Therapy, Combination; Humans; | 1980 |
Study of migraine and the treatment of acute attacks in industry.
Topics: Absenteeism; Acetaminophen; Adolescent; Adult; England; Female; Humans; Male; Metoclopramide; Middle | 1980 |
[Variant angina pectoris related to the treatment of migraine].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Angina Pectoris, Variant; Drug Combinations; Echocardiograp | 1995 |
[Biliary pain after ingestion of paracetamol and codeine].
Topics: Abdominal Pain; Acetaminophen; Cholecystectomy; Cholelithiasis; Codeine; Drug Therapy, Combination; | 1995 |
Myocardial infarction induced by migraine therapy.
Topics: Acetaminophen; Adult; Antipyrine; Chloral Hydrate; Coronary Vasospasm; Drug Combinations; Female; Hu | 1995 |
[Headache caused by analgesics].
Topics: Acetaminophen; Adult; Female; Headache; Humans; Middle Aged; Migraine Disorders; Sumatriptan | 1994 |
Migraine.
Topics: Acetaminophen; Adult; Aspirin; Child; Diphenhydramine; Histamine H1 Antagonists; Humans; Ibuprofen; | 1993 |
Anorectal stenosis in patients with prolonged use of suppositories containing paracetamol and acetylsalicylic acid.
Topics: Acetaminophen; Administration, Rectal; Adult; Anus Diseases; Aspirin; Constriction, Pathologic; Drug | 1993 |
[Rectal stenosis following prolonged use of suppositories of acetylsalicylic acid and paracetamol. Correction by perineal approach].
Topics: Acetaminophen; Aged; Aspirin; Female; Humans; Intestinal Obstruction; Migraine Disorders; Perineum; | 1995 |
[Paracetamol and metoclopramide in fixed combination?].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antiemetics; Drug Combinations; Humans; Metoclopramide; Mig | 1996 |
Effects of antimigraine drugs on retinal spreading depression.
Topics: Acetaminophen; Adrenergic beta-Antagonists; Adrenochrome; Analgesics, Non-Narcotic; Animals; Aspirin | 1996 |
Acetaminophen anaphylaxis with aspirin and sodium salicylate sensitivity: a case report.
Topics: Acetaminophen; Adolescent; Anaphylaxis; Aspirin; Cross Reactions; Drug Hypersensitivity; Female; Hum | 1996 |
Serotonin and analgesic-related headache.
Topics: Acetaminophen; Analgesics; Blood Platelets; Codeine; Headache; Humans; Migraine Disorders; Receptors | 1996 |
[Clinical features of daily chronic headache].
Topics: Acetaminophen; Adult; Age of Onset; Analgesics; Benzodiazepines; Caffeine; Chronic Disease; Ergotami | 1997 |
Platelet sulphotransferase activity, plasma sulphate levels and sulphation capacity in patients with migraine and tension headache.
Topics: Acetaminophen; Adult; Arylsulfotransferase; Blood Platelets; Case-Control Studies; Female; Humans; M | 1997 |
[The efficacy of Solpadeine in patients with primary forms of headache].
Topics: Acetaminophen; Adult; Analgesics; Caffeine; Codeine; Drug Combinations; Drug Evaluation; Female; Hum | 1997 |
Minimizing migraines.
Topics: Acetaminophen; Aspirin; Caffeine; Drug Combinations; Humans; Migraine Disorders; Riboflavin | 1998 |
Figurate purpuric eruptions on the trunk: acetaminophen-induced rashes.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Biopsy, Needle; Drug Eruptions; Exanthema; Follow-Up | 1998 |
Limitations of acetaminophen, aspirin, and caffeine in alleviating migraine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; | 1998 |
[Migraine treatment].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspir | 2000 |
[Hemiplegic migraine. A series of 5 patients].
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspiri | 2000 |
[Migraine therapy in pregnancy. Paracetamol leads in acute therapy].
Topics: Acetaminophen; Analgesics; Combined Modality Therapy; Female; Humans; Infant, Newborn; Migraine Diso | 1999 |
Migraine in older patients: a case report and management strategies.
Topics: Acetaminophen; Aged; Aged, 80 and over; Antipyrine; Cheese; Chloral Hydrate; Diagnosis, Differential | 2000 |
Warning: the excedrin migraine warning label is inadequate to warn consumers of the risk of medication rebound headache.
Topics: Acetaminophen; Adult; Aspirin; Caffeine; Drug Combinations; Drug Labeling; Female; Humans; Migraine | 1999 |
Migraine, Midrin, and Imitrex.
Topics: Acetaminophen; Antipyrine; Chloral Hydrate; Drug Combinations; Humans; Methylamines; Migraine Disord | 2002 |
[Experience with 750 migraine patients at a headache clinic].
Topics: Acetaminophen; Adult; Aged; Aspirin; Diazepam; Drug Evaluation; Drug Therapy, Combination; Female; H | 1979 |
[Migraeflux; results in the field study of an anti-migraine agent].
Topics: Acetaminophen; Codeine; Dimenhydrinate; Drug Combinations; Drug Evaluation; Migraine Disorders | 1978 |
The diagnosis and management of migraine.
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Aspirin; Child; Clonidine; Ergotamine; Ergotamines; F | 1978 |
[The use of drugs in migraine].
Topics: Acetaminophen; Antiemetics; Aspirin; Clonidine; Dihydroergotamine; Ergotamine; Humans; Hypnotics and | 1976 |
Editorial: The treatment of acute migraine attacks.
Topics: Acetaminophen; Acute Disease; Antiemetics; Aspirin; Caffeine; Ergotamine; Humans; Hypnotics and Seda | 1976 |
[Pharmacokinetic aspects of a combination of metoclopramide and paracetamol. Results of a human kinetic study and consequences for migraine patients].
Topics: Acetaminophen; Adult; Biological Availability; Drug Combinations; Female; Half-Life; Humans; Male; M | 1992 |
Migraine--treatment of acute attack.
Topics: Acetaminophen; Acute Disease; Aspirin; Caffeine; Ergotamine; Ergotamines; Humans; Metoclopramide; Mi | 1985 |
Autonomic dysreflexia due to medication: misadventure in the use of an isometheptene combination to treat migraine.
Topics: Acetaminophen; Adult; Antipyrine; Autonomic Nervous System; Blood Pressure; Chloral Hydrate; Drug Co | 1985 |
Headache.
Topics: Acetaminophen; Anti-Bacterial Agents; Chlordiazepoxide; Headache; Humans; Migraine Disorders; Sinusi | 1972 |
Migraine--treatment of acute attack.
Topics: Acetaminophen; Acute Disease; Administration, Oral; Antiemetics; Aspirin; Child; Ergotamine; Female; | 1971 |