Page last updated: 2024-10-22

acetaminophen and Mental Disorders

acetaminophen has been researched along with Mental Disorders in 34 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Research Excerpts

ExcerptRelevanceReference
"Our study showed that both eletriptan and paracetamol relieve post-ECT headaches, but eletriptan showed superiority in reducing the intensity and duration of the headaches in this small treatment group."9.20Headache treatment after electroconvulsive treatment: a single-blinded trial comparator between eletriptan and paracetamol. ( Kertesz, DP; Trabekin, O; Vanetik, MS, 2015)
"Acetaminophen (paracetamol) is the most commonly used medication for pain and fever during pregnancy in many countries."7.80Acetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders. ( Lee, PC; Liew, Z; Olsen, J; Rebordosa, C; Ritz, B, 2014)
"This study intended to determine the prevalence of hypokalemia and its clinical correlates in acute psychiatric illness among hypokalemic and normokalemic patients after acetaminophen overdose."7.76High prevalence of hypokalemia after acute acetaminophen overdose: impact of psychiatric illness. ( Al-jabi, SW; Awang, R; Syed Sulaiman, SA; Zyoud, SH, 2010)
"Our study showed that both eletriptan and paracetamol relieve post-ECT headaches, but eletriptan showed superiority in reducing the intensity and duration of the headaches in this small treatment group."5.20Headache treatment after electroconvulsive treatment: a single-blinded trial comparator between eletriptan and paracetamol. ( Kertesz, DP; Trabekin, O; Vanetik, MS, 2015)
"Acetaminophen (paracetamol) is the most commonly used medication for pain and fever during pregnancy in many countries."3.80Acetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders. ( Lee, PC; Liew, Z; Olsen, J; Rebordosa, C; Ritz, B, 2014)
"This study intended to determine the prevalence of hypokalemia and its clinical correlates in acute psychiatric illness among hypokalemic and normokalemic patients after acetaminophen overdose."3.76High prevalence of hypokalemia after acute acetaminophen overdose: impact of psychiatric illness. ( Al-jabi, SW; Awang, R; Syed Sulaiman, SA; Zyoud, SH, 2010)
"Pharmacotherapy in pregnancy is often problematic, since both the mother-to-be and her doctor are often concerned about possible risks for the unborn child."2.42[Drug therapy in pregnancy--a practical guide]. ( Kreienberg, R; Paulus, W; Reister, F, 2004)
"She developed a complete recto-anal stenosis and bowel obstruction requiring permanent colostomy."2.39[Complete anorectal stenosis due to paracetamol and salicylamide suppositories]. ( Aguilera, MJ; Díaz, J; Galindo, A; Marijuan, JL; Mata, A, 1995)
"Women with migraine, rheumatoid arthritis and mental disease showed the highest risk of frequent use."1.91Paracetamol use prior to and in early pregnancy: Prevalence and patterns among women with and without chronic medical diseases. ( Damm, P; de Wolff, MG; Fisher, MB; Hagen, CP; Hegaard, HK; Rode, L; Rom, AL; Taagaard, M, 2023)
"Sertraline (SSRI) was the most frequently prescribed antidepressant."1.36A cross-sectional observation of the factors associated with deliberate self-poisoning with acetaminophen: impact of gender differences and psychiatric intervention. ( Al-Jabi, SW; Awang, R; Sulaiman, SA; Zyoud, SH, 2010)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.94)18.7374
1990's2 (5.88)18.2507
2000's6 (17.65)29.6817
2010's22 (64.71)24.3611
2020's3 (8.82)2.80

Authors

AuthorsStudies
Taagaard, M1
Rode, L1
de Wolff, MG1
Damm, P1
Hagen, CP1
Fisher, MB1
Hegaard, HK1
Rom, AL1
Warrillow, S1
Tibballs, H1
Bailey, M1
McArthur, C1
Lawson-Smith, P1
Prasad, B1
Anstey, M1
Venkatesh, B1
Dashwood, G1
Walsham, J1
Holt, A1
Wiersema, U1
Gattas, D1
Zoeller, M1
Garcia Alvarez, M1
Bellomo, R1
Simmons, OL1
Meinzer, C1
Rule, J1
Lee, WM3
Farkas, A1
Lipanot, K1
Sherman, K1
Galletly, C1
Rangnekar, AS1
Ellerbe, C1
Durkalski, V1
McGuire, B1
Fontana, RJ1
Teo, AI1
Cooper, JG1
Brandlistuen, RE3
Ystrom, E3
Nulman, I3
Koren, G3
Nordeng, H3
Cannell, JJ1
Cooper, M1
Langley, K1
Thapar, A1
Liew, Z2
Ritz, B2
Rebordosa, C1
Lee, PC1
Olsen, J2
Appel, J1
Vaidya, S1
Amitai, Y1
Kertesz, DP1
Trabekin, O1
Vanetik, MS1
Damkier, P1
Pottegård, A1
dePont Christensen, R1
Hallas, J1
Dickerson, DL1
Schaepper, MA1
Peterson, MD1
Ashworth, MD1
Carson, HJ1
Eilers, SG1
Kimlin, EJ1
Easter, JS1
Ganetsky, M1
Forde, KA1
Reddy, KR1
Troxel, AB1
Sanders, CM1
Khan, LR1
Oniscu, GC1
Powell, JJ1
Zyoud, SH2
Awang, R2
Syed Sulaiman, SA1
Al-jabi, SW2
Karvellas, CJ1
Safinia, N1
Auzinger, G1
Heaton, N1
Muiesan, P1
O'Grady, J1
Wendon, J1
Bernal, W1
Sulaiman, SA1
Benger, JR1
Rhodes, R1
Aggarwal, S1
Schiano, TD1
Kjartansdottir, I1
Bergmann, OM1
Arnadottir, RS1
Björnsson, ES1
Reister, F1
Paulus, W1
Kreienberg, R1
Chibnall, JT1
Tait, RC1
Harman, B1
Luebbert, RA1
Mata, A1
Galindo, A1
Díaz, J1
Marijuan, JL1
Aguilera, MJ1
Hannah, P1
Malizia, A1
Glover, V1
Bridges, P1
Sandler, M1
Naess, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multi-Center Trial to Study Acute Liver Failure in Adults[NCT00518440]3,488 participants (Actual)Observational1998-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for acetaminophen and Mental Disorders

ArticleYear
Ethical dilemmas in psychiatric evaluations in patients with fulminant liver failure.
    Current opinion in organ transplantation, 2014, Volume: 19, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Ethics, Medical; Humans; Intelligence Tests; Liver Failure,

2014
[Drug therapy in pregnancy--a practical guide].
    MMW Fortschritte der Medizin, 2004, Mar-11, Volume: 146, Issue:11

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Bacte

2004
[Complete anorectal stenosis due to paracetamol and salicylamide suppositories].
    Revista espanola de enfermedades digestivas, 1995, Volume: 87, Issue:6

    Topics: Acetaminophen; Adult; Anus Diseases; Codeine; Colostomy; Constriction, Pathologic; Drug Combinations

1995

Trials

3 trials available for acetaminophen and Mental Disorders

ArticleYear
Headache treatment after electroconvulsive treatment: a single-blinded trial comparator between eletriptan and paracetamol.
    The journal of ECT, 2015, Volume: 31, Issue:2

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Electroconvulsive Therapy;

2015
Effect of acetaminophen on behavior, well-being, and psychotropic medication use in nursing home residents with moderate-to-severe dementia.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:11

    Topics: Acetaminophen; Activities of Daily Living; Affective Symptoms; Aged; Aged, 80 and over; Alzheimer Di

2005
Paracetamol (acetominophen) sulphoconjugation in man: no correlation with tyramine sulphoconjugation.
    Drug metabolism and drug interactions, 1996, Volume: 13, Issue:2

    Topics: Acetaminophen; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Chromatography, High Pressure Li

1996

Other Studies

28 other studies available for acetaminophen and Mental Disorders

ArticleYear
Paracetamol use prior to and in early pregnancy: Prevalence and patterns among women with and without chronic medical diseases.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:8

    Topics: Acetaminophen; Female; Humans; Mental Disorders; Migraine Disorders; Pain Management; Pregnancy; Pre

2023
Characteristics, management and outcomes of patients with acute liver failure admitted to Australasian intensive care units.
    Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2019, Volume: 21, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Australia; Drug Overdose; Female; Humans

2019
Liver Transplantation for Acetaminophen-Induced Acute Liver Failure: Role of Psychiatric Comorbidity in Listing Decisions and Outcomes.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Cohort Studi

2020
Routine Laboratory Screening for Acetaminophen and Salicylate Ingestion in Preadmission Psychiatric Patients Is Unnecessary.
    Annals of emergency medicine, 2021, Volume: 77, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Aged; Diagnostic Tests, Routine; Drug Overdose; Emergency Service,

2021
Paracetamol, pregnancy and public health.
    The Australian and New Zealand journal of psychiatry, 2019, Volume: 53, Issue:3

    Topics: Acetaminophen; Adverse Childhood Experiences; Female; Hallucinogens; Humans; Mental Disorders; Pregn

2019
Quality of life is significantly impaired in long-term survivors of acute liver failure and particularly in acetaminophen-overdose patients.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2013, Volume: 19, Issue:9

    Topics: Acetaminophen; Adult; Coma; Drug Overdose; Female; Follow-Up Studies; Humans; Liver Failure, Acute;

2013
The epidemiology and management of adult poisonings admitted to the short-stay ward of a large Scottish emergency department.
    Scottish medical journal, 2013, Volume: 58, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic;

2013
Prenatal paracetamol exposure and child neurodevelopment: a sibling-controlled cohort study.
    International journal of epidemiology, 2013, Volume: 42, Issue:6

    Topics: Acetaminophen; Aggression; Analgesics, Non-Narcotic; Anxiety; Case-Control Studies; Child Developmen

2013
Paracetamol, oxidative stress, vitamin D and autism spectrum disorders.
    International journal of epidemiology, 2014, Volume: 43, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Development; Female; Humans; Male; Mental Disorders;

2014
Authors' Response: More research on paracetamol is required.
    International journal of epidemiology, 2014, Volume: 43, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Development; Female; Humans; Male; Mental Disorders;

2014
Antenatal acetaminophen use and attention-deficit/hyperactivity disorder: an interesting observed association but too early to infer causality.
    JAMA pediatrics, 2014, Volume: 168, Issue:4

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Female; Humans; Hyperkinesis; Male; Me

2014
Acetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders.
    JAMA pediatrics, 2014, Volume: 168, Issue:4

    Topics: Acetaminophen; Adult; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Denmar

2014
Characteristics of acetaminophen users compared with nonusers during pregnancy, behavioral problems, and hyperkinetic disorders.
    JAMA pediatrics, 2014, Volume: 168, Issue:9

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Female; Humans; Hyperkinesis; Male; Me

2014
Characteristics of acetaminophen users compared with nonusers during pregnancy, behavioral problems, and hyperkinetic disorders--reply.
    JAMA pediatrics, 2014, Volume: 168, Issue:9

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Female; Humans; Hyperkinesis; Male; Me

2014
Annotations and reflections: pregnancy and paracetamol: methodological considerations on the study of associations between in utero exposure to drugs and childhood neurodevelopment.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 116, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Development; Female; Humans; Male; Mental Disorders;

2015
Annotations and reflections: response to "Pregnancy and paracetamol: methodological considerations on the study of associations between in utero exposure to drugs and childhood neurodevelopment".
    Basic & clinical pharmacology & toxicology, 2015, Volume: 116, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Development; Female; Humans; Male; Mental Disorders;

2015
Coricidin HBP abuse: patient characteristics and psychiatric manifestations as recorded in an inpatient psychiatric unit.
    Journal of addictive diseases, 2008, Volume: 27, Issue:1

    Topics: Acetaminophen; Adolescent; Age Factors; Alcoholism; California; Child; Chlorpheniramine; Comorbidity

2008
Death from undiagnosed glioblastoma multiforme and toxic self-medication presenting with concurrent dysfunctional behavior.
    Journal of forensic and legal medicine, 2008, Volume: 15, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Brain Edema; Brain Neoplasms; Dextropro

2008
A 46-year-old woman with altered mental status and garbled speech.
    The Journal of emergency medicine, 2009, Volume: 37, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Diagnosis, Differential; Diphenhydramine; Electrocardiography; Female

2009
Racial and ethnic differences in presentation, etiology, and outcomes of acute liver failure in the United States.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2009, Volume: 7, Issue:10

    Topics: Acetaminophen; Adult; Animals; Cohort Studies; Ethnicity; Female; Humans; Liver Failure, Acute; Live

2009
Long-term outcome following liver transplantation for paracetamol overdose.
    Transplant international : official journal of the European Society for Organ Transplantation, 2010, May-01, Volume: 23, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Drug Overdose; Female; Graft Survival; H

2010
High prevalence of hypokalemia after acute acetaminophen overdose: impact of psychiatric illness.
    Human & experimental toxicology, 2010, Volume: 29, Issue:9

    Topics: Acetaminophen; Adjustment Disorders; Adolescent; Adult; Anxiety Disorders; Cohort Studies; Depressiv

2010
Medical and psychiatric outcomes for patients transplanted for acetaminophen-induced acute liver failure: a case-control study.
    Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; APACHE; Case-Control Studies; Chemical and Drug Indu

2010
A cross-sectional observation of the factors associated with deliberate self-poisoning with acetaminophen: impact of gender differences and psychiatric intervention.
    Human psychopharmacology, 2010, Volume: 25, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Age Factors; Antidepressive Agents; Cross-Sectional Studies; Depre

2010
Advanced directives and suicidal behaviour. "If in doubt treat" is not as easy as it sounds.
    BMJ (Clinical research ed.), 2010, Oct-05, Volume: 341

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Overdose; Humans; Mental Competency; Mental Disorders;

2010
Overdose with suicidal intent: ethical considerations for liver transplant programs.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2011, Volume: 17, Issue:9

    Topics: Acetaminophen; Adult; Drug Overdose; Ethics, Medical; Female; Humans; Liver Failure, Acute; Liver Tr

2011
Paracetamol intoxications: a retrospective population-based study in Iceland.
    Scandinavian journal of gastroenterology, 2012, Volume: 47, Issue:11

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Age Factors; Aged; Analgesics, Non-Narcotic; Chemic

2012
[Risks in long-term treatment with analgesics].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Mar-30, Volume: 93, Issue:9

    Topics: Acetaminophen; Analgesics; Antipyrine; Aspirin; Caffeine; Diuresis; Drug Combinations; Humans; Kidne

1973