acetaminophen has been researched along with Melanoma in 14 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The combination of dabrafenib and trametinib (CombiDT) is an effective treatment for BRAF-mutant metastatic melanoma; however, over 70% of patients develop drug-related pyrexia, and little is known about this toxicity." | 9.19 | Features and management of pyrexia with combined dabrafenib and trametinib in metastatic melanoma. ( Azer, M; Clements, A; Haydu, LE; Kefford, RF; Lee, CI; Long, GV; Menzies, AM, 2014) |
| " We conducted a phase I trial of high dose paracetamol and carmustine (BCNU) in patients with advanced malignant melanoma to determine the optimal biological dose and the maximum tolerated dose (MTD) with the goal of increasing sensitivity to BCNU by GSH depletion." | 9.10 | Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma. ( Chang, C; Chapman, PB; Fleisher, M; Hwu, WJ; Krown, SE; Livingston, PO; Pinto, JT; Williams, L; Wolchok, JD, 2003) |
| "In this work, we investigated the biochemical mechanism of acetaminophen (APAP) induced toxicity in SK-MEL-28 melanoma cells using tyrosinase enzyme as a molecular cancer therapeutic target." | 7.75 | Biochemical mechanism of acetaminophen (APAP) induced toxicity in melanoma cell lines. ( Moore, D; Moridani, MY; Vad, NM; Weidanz, J; Yount, G, 2009) |
| "The combination of dabrafenib and trametinib (CombiDT) is an effective treatment for BRAF-mutant metastatic melanoma; however, over 70% of patients develop drug-related pyrexia, and little is known about this toxicity." | 5.19 | Features and management of pyrexia with combined dabrafenib and trametinib in metastatic melanoma. ( Azer, M; Clements, A; Haydu, LE; Kefford, RF; Lee, CI; Long, GV; Menzies, AM, 2014) |
| " We conducted a phase I trial of high dose paracetamol and carmustine (BCNU) in patients with advanced malignant melanoma to determine the optimal biological dose and the maximum tolerated dose (MTD) with the goal of increasing sensitivity to BCNU by GSH depletion." | 5.10 | Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma. ( Chang, C; Chapman, PB; Fleisher, M; Hwu, WJ; Krown, SE; Livingston, PO; Pinto, JT; Williams, L; Wolchok, JD, 2003) |
| "Neither aspirin nor non-aspirin NSAID use was associated with a lower risk of melanoma, SCC, or BCC, even for women with high quantity, frequency, or duration of use." | 3.78 | Non-steroidal anti-inflammatory drugs, acetaminophen, and risk of skin cancer in the Nurses' Health Study. ( Alberts, DS; Feskanich, D; Han, J; Jeter, JM; Martinez, ME; Qureshi, AA, 2012) |
| "In this work, we investigated the biochemical mechanism of acetaminophen (APAP) induced toxicity in SK-MEL-28 melanoma cells using tyrosinase enzyme as a molecular cancer therapeutic target." | 3.75 | Biochemical mechanism of acetaminophen (APAP) induced toxicity in melanoma cell lines. ( Moore, D; Moridani, MY; Vad, NM; Weidanz, J; Yount, G, 2009) |
| " We describe a patient with metastatic melanoma who developed a multifocal FDE to paracetamol, tropisetron and ondansetron during chemoimmunotherapy with interleukin 2 (IL-2) and dacarbazine." | 3.70 | Multifocal fixed drug eruption to paracetamol, tropisetron and ondansetron induced by interleukin 2. ( Bernand, S; Burg, G; Dummer, R; Scheidegger, EP, 2000) |
| "Fever is frequently observed in conjunction with interleukin-2 (IL-2)-based immunotherapy." | 1.42 | Fever and the use of paracetamol during IL-2-based immunotherapy in metastatic melanoma. ( Bastholt, L; Christensen, IJ; Ellegaard, MB; Køstner, AH; Schmidt, H, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El Sayed, SM | 2 |
| Mohamed, WG | 1 |
| Seddik, MA | 1 |
| Ahmed, AS | 1 |
| Mahmoud, AG | 1 |
| Amer, WH | 1 |
| Helmy Nabo, MM | 1 |
| Hamed, AR | 1 |
| Ahmed, NS | 1 |
| Abd-Allah, AA | 1 |
| Harris, K | 1 |
| Calder, S | 1 |
| Larsen, B | 1 |
| Duffy, K | 1 |
| Bowen, G | 1 |
| Tristani-Firouzi, P | 1 |
| Hadley, M | 1 |
| Endo, J | 1 |
| Lee, CI | 1 |
| Menzies, AM | 1 |
| Haydu, LE | 1 |
| Azer, M | 1 |
| Clements, A | 1 |
| Kefford, RF | 1 |
| Long, GV | 1 |
| Køstner, AH | 1 |
| Ellegaard, MB | 1 |
| Christensen, IJ | 1 |
| Bastholt, L | 1 |
| Schmidt, H | 1 |
| Baghdadi, H | 1 |
| Zolaly, M | 1 |
| Almaramhy, HH | 1 |
| Ayat, M | 1 |
| Donki, JG | 1 |
| Ueno, M | 1 |
| Namiki, T | 1 |
| Inui, K | 1 |
| Hanafusa, T | 1 |
| Miura, K | 1 |
| Yokozeki, H | 1 |
| Asgari, MM | 1 |
| Maruti, SS | 1 |
| White, E | 1 |
| Vad, NM | 1 |
| Yount, G | 1 |
| Moore, D | 1 |
| Weidanz, J | 1 |
| Moridani, MY | 1 |
| Sniezek, PJ | 1 |
| Brodland, DG | 1 |
| Zitelli, JA | 1 |
| Smart, M | 1 |
| Jeter, JM | 1 |
| Han, J | 1 |
| Martinez, ME | 1 |
| Alberts, DS | 1 |
| Qureshi, AA | 1 |
| Feskanich, D | 1 |
| Wolchok, JD | 1 |
| Williams, L | 1 |
| Pinto, JT | 1 |
| Fleisher, M | 1 |
| Krown, SE | 1 |
| Hwu, WJ | 1 |
| Livingston, PO | 1 |
| Chang, C | 1 |
| Chapman, PB | 1 |
| Bernand, S | 1 |
| Scheidegger, EP | 1 |
| Dummer, R | 1 |
| Burg, G | 1 |
| Fabris, P | 1 |
| Dalla Palma, M | 1 |
| de Lalla, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Trial of Bupivacaine as Adjuvant for Post-operative Pain in Mohs Micrographic Surgery[NCT04362566] | Phase 4 | 174 participants (Actual) | Interventional | 2020-07-30 | Completed | ||
| Hypoalgesic Effect of Median Nerve Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02596815] | 51 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Hypoalgesic Effect of Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02595294] | 52 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain[NCT02593721] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetaminophen and Melanoma
| Article | Year |
|---|---|
Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study.
Topics: Acetaminophen; Adult; Carcinoma, Hepatocellular; Disease Progression; Drug Therapy, Combination; Enz | 2014 |
3 trials available for acetaminophen and Melanoma
| Article | Year |
|---|---|
Features and management of pyrexia with combined dabrafenib and trametinib in metastatic melanoma.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antine | 2014 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antineoplastic Agents, Alkylating; Carmusti | 2003 |
10 other studies available for acetaminophen and Melanoma
| Article | Year |
|---|---|
Opioid prescribing patterns after Mohs micrographic surgery and standard excision: a survey of American Society for Dermatologic Surgery members and a chart review at a single institution.
Topics: Acetaminophen; Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Carcinoma, Basal Cell; Carc | 2014 |
Fever and the use of paracetamol during IL-2-based immunotherapy in metastatic melanoma.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antineoplastic Combined Chemothera | 2015 |
The promising anticancer drug 3-bromopyruvate is metabolized through glutathione conjugation which affects chemoresistance and clinical practice: An evidence-based view.
Topics: Acetaminophen; Administration, Oral; Albumins; Alkylating Agents; Animals; Antineoplastic Agents; Ci | 2017 |
Neutrophilic panniculitis with vasculitis in a melanoma patient treated with vemurafenib: a case report and its management.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antineoplast | 2017 |
A large cohort study of nonsteroidal anti-inflammatory drug use and melanoma incidence.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Comorbidity; Confoundi | 2008 |
Biochemical mechanism of acetaminophen (APAP) induced toxicity in melanoma cell lines.
Topics: Acetaminophen; Animals; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cell Survival | 2009 |
Oncology update.
Topics: Acetaminophen; Antibodies, Monoclonal; Carcinoma, Non-Small-Cell Lung; Drug Approval; Humans; Lung N | 2011 |
Non-steroidal anti-inflammatory drugs, acetaminophen, and risk of skin cancer in the Nurses' Health Study.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Basal Cell; Carcinoma, S | 2012 |
Multifocal fixed drug eruption to paracetamol, tropisetron and ondansetron induced by interleukin 2.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiemetics; Drug Eruptions; Drug Interactions; Huma | 2000 |
Idiosyncratic acute hepatitis caused by paracetamol in two patients with melanoma treated with high-dose interferon-alpha.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Antineoplastic Agents; Chemical and Drug Ind | 2001 |