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acetaminophen and Lung Injury, Acute

acetaminophen has been researched along with Lung Injury, Acute in 12 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"Propacetamol is an APAP prodrug, which is clinically bioequivalent to APAP."5.48Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice. ( Ko, JL; Lai, YY; Liou, GG; Tsai, MS; Tsou, HK; Wang, SH; Wang, YH, 2018)
" Furthermore, autophagy intervention experiments were achieved by the administration of rapamycin (RAPA) or chloroquine (CQ) one hour prior to dosing 300 mg/kg APAP."1.51Mitophagy protects against acetaminophen-induced acute liver injury in mice through inhibiting NLRP3 inflammasome activation. ( Kou, R; Shan, S; Shen, Z; Song, F; Xie, K; Zhang, C, 2019)
"Propacetamol is an APAP prodrug, which is clinically bioequivalent to APAP."1.48Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice. ( Ko, JL; Lai, YY; Liou, GG; Tsai, MS; Tsou, HK; Wang, SH; Wang, YH, 2018)
"Acetaminophen (APAP) is a safe analgesic and antipyretic drug."1.38Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure. ( Amaral, SS; Avila, TV; Cara, DC; De Paula, AM; Leite, MF; Lima, BH; Lima, CX; Lopes, GA; Marques, PE; Melgaço, JG; Menezes, GB; Nogueira, LL; Oliveira, AG; Pinto, MA; Pires, DA; Russo, RC; Soriani, FM; Teixeira, MM, 2012)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (91.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Zheng, Y1
Wang, J1
Ling, Z1
Zhang, J1
Zeng, Y1
Wang, K1
Zhang, Y1
Nong, L1
Sang, L1
Xu, Y1
Liu, X1
Li, Y1
Huang, Y1
Shan, S1
Shen, Z1
Zhang, C1
Kou, R1
Xie, K1
Song, F1
Qi, J1
Zhou, Z1
Lim, CW1
Kim, JW1
Kim, B1
Sydor, S1
Manka, P1
Best, J1
Jafoui, S1
Sowa, JP1
Zoubek, ME1
Hernandez-Gea, V1
Cubero, FJ1
Kälsch, J1
Vetter, D1
Fiel, MI1
Hoshida, Y1
Bian, CB1
Nelson, LJ1
Moshage, H1
Faber, KN1
Paul, A1
Baba, HA1
Gerken, G1
Friedman, SL1
Canbay, A1
Bechmann, LP1
Tsai, MS1
Wang, YH1
Lai, YY1
Tsou, HK1
Liou, GG1
Ko, JL1
Wang, SH1
Li, M1
Qin, XY1
Furutani, Y1
Inoue, I1
Sekihara, S1
Kagechika, H1
Kojima, S1
Wu, KC1
Ho, YL1
Kuo, YH1
Huang, SS1
Huang, GJ1
Chang, YS1
Park, MJ1
D'Alecy, LG1
Anderson, MA1
Basrur, V1
Feng, Y1
Brady, GF1
Kim, DI1
Wu, J1
Nesvizhskii, AI1
Lahann, J1
Lukacs, NW1
Fontana, RJ1
Omary, MB1
Richards, JA1
Bucsaiova, M1
Hesketh, EE1
Ventre, C1
Henderson, NC1
Simpson, K1
Bellamy, CO1
Howie, SE1
Anderton, SM1
Hughes, J1
Wigmore, SJ1
Yadav, N1
Kanjirakkuzhiyil, S1
Ramakrishnan, M1
Das, TK1
Mukhopadhyay, A1
Marques, PE1
Amaral, SS1
Pires, DA1
Nogueira, LL1
Soriani, FM1
Lima, BH1
Lopes, GA1
Russo, RC1
Avila, TV1
Melgaço, JG1
Oliveira, AG1
Pinto, MA1
Lima, CX1
De Paula, AM1
Cara, DC1
Leite, MF1
Teixeira, MM1
Menezes, GB1
Schmelzle, M1
Splith, K1
Andersen, LW1
Kornek, M1
Schuppan, D1
Jones-Bamman, C1
Nowak, M1
Toxavidis, V1
Salhanick, SD1
Han, L1
Schulte am Esch, J1
Jonas, S1
Donnino, MW1
Robson, SC1

Other Studies

12 other studies available for acetaminophen and Lung Injury, Acute

ArticleYear
A diagnostic model for sepsis-induced acute lung injury using a consensus machine learning approach and its therapeutic implications.
    Journal of translational medicine, 2023, 09-12, Volume: 21, Issue:1

    Topics: Acetaminophen; Acute Lung Injury; Consensus; Humans; Machine Learning; rho Guanine Nucleotide Dissoc

2023
Mitophagy protects against acetaminophen-induced acute liver injury in mice through inhibiting NLRP3 inflammasome activation.
    Biochemical pharmacology, 2019, Volume: 169

    Topics: Acetaminophen; Acute Lung Injury; Animals; Chloroquine; Inflammasomes; Male; Mice; Mice, Inbred C57B

2019
Amlexanox ameliorates acetaminophen-induced acute liver injury by reducing oxidative stress in mice.
    Toxicology and applied pharmacology, 2019, 12-15, Volume: 385

    Topics: Acetaminophen; Acute Lung Injury; Aminopyridines; AMP-Activated Protein Kinases; Animals; Cells, Cul

2019
Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury.
    Scientific reports, 2017, 08-14, Volume: 7, Issue:1

    Topics: Acetaminophen; Acute Lung Injury; Animals; Autophagy; Carbon Tetrachloride; Carcinoma, Hepatocellula

2017
Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice.
    Toxicology letters, 2018, Jun-15, Volume: 290

    Topics: Acetaminophen; Acetylcysteine; Acute Lung Injury; Animals; Apoptosis; Cytochrome P-450 CYP2E1; DNA D

2018
Prevention of acute liver injury by suppressing plasma kallikrein-dependent activation of latent TGF-β.
    Biochemical and biophysical research communications, 2018, 10-12, Volume: 504, Issue:4

    Topics: Acetaminophen; Acute Lung Injury; Animals; Antibodies, Monoclonal; Benzamides; Biomarkers; Chemical

2018
Hepatoprotective Effect of Ugonin M, A
    Molecules (Basel, Switzerland), 2018, Sep-21, Volume: 23, Issue:10

    Topics: Acetaminophen; Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Disea

2018
Constitutive release of CPS1 in bile and its role as a protective cytokine during acute liver injury.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 04-30, Volume: 116, Issue:18

    Topics: Acetaminophen; Acute Lung Injury; Adult; Animals; Bile; Bile Acids and Salts; Carbamoyl-Phosphate Sy

2019
Acute Liver Injury Is Independent of B Cells or Immunoglobulin M.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Acetaminophen; Acute Lung Injury; Animals; B-Lymphocytes; Chemical and Drug Induced Liver Injury; Di

2015
Factor VIII can be synthesized in hemophilia A mice liver by bone marrow progenitor cell-derived hepatocytes and sinusoidal endothelial cells.
    Stem cells and development, 2012, Volume: 21, Issue:1

    Topics: Acetaminophen; Acute Lung Injury; Animals; Bone Marrow Cells; Cell Differentiation; Endothelial Cell

2012
Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure.
    Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:5

    Topics: Acetaminophen; Acute Lung Injury; Acute-Phase Reaction; Adolescent; Adult; Analysis of Variance; Ani

2012
Increased plasma levels of microparticles expressing CD39 and CD133 in acute liver injury.
    Transplantation, 2013, Jan-15, Volume: 95, Issue:1

    Topics: AC133 Antigen; Acetaminophen; Acute Lung Injury; Animals; Antigens, CD; Apyrase; Biomarkers; Cell-De

2013