acetaminophen has been researched along with Joint Pain in 37 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare acetaminophen extended release 1,300 mg 3 times daily and ibuprofen 400 mg 3 times daily for treatment of signs and symptoms of grade I or II lateral ankle sprains." | 9.12 | Randomized controlled noninferiority trial to compare extended release acetaminophen and ibuprofen for the treatment of ankle sprains. ( Dalton, JD; Schweinle, JE, 2006) |
| "Adult patients with pain from osteoarthritis receiving a stable dosage of HCD/APAP (i." | 6.77 | A randomized, 14-day, double-blind study evaluating conversion from hydrocodone/acetaminophen (Vicodin) to buprenorphine transdermal system 10 μg/h or 20 μg/h in patients with osteoarthritis pain. ( Landau, CJ; McCarberg, BH; Munera, C; Ripa, SR; Wen, W, 2012) |
| "To compare acetaminophen extended release 1,300 mg 3 times daily and ibuprofen 400 mg 3 times daily for treatment of signs and symptoms of grade I or II lateral ankle sprains." | 5.12 | Randomized controlled noninferiority trial to compare extended release acetaminophen and ibuprofen for the treatment of ankle sprains. ( Dalton, JD; Schweinle, JE, 2006) |
| " However, randomized trials have demonstrated success with high-dose steroids, cyclosporine, and mycophenolate in treating glomerulonephritis and other complications." | 5.05 | Henoch-Schönlein Purpura (IgA Vasculitis): Rapid Evidence Review. ( Reamy, BV; Servey, JT; Williams, PM, 2020) |
| "This paper reports on a study conducted to describe what traditional and non-traditional treatments older adults with osteoarthritis use for pain management, their reported pain relief, and factors associated with use of recommended initial gold standard treatment (acetaminophen/paracetamol or non-steroidal anti-inflammatory drugs, and exercise and/or physical therapy) as designated by conventional western medicine." | 3.75 | Use of recommended osteoarthritis pain treatment by older adults. ( McDonald, DD; Merkle, D, 2009) |
| "Adult patients with pain from osteoarthritis receiving a stable dosage of HCD/APAP (i." | 2.77 | A randomized, 14-day, double-blind study evaluating conversion from hydrocodone/acetaminophen (Vicodin) to buprenorphine transdermal system 10 μg/h or 20 μg/h in patients with osteoarthritis pain. ( Landau, CJ; McCarberg, BH; Munera, C; Ripa, SR; Wen, W, 2012) |
| "Rofecoxib treatment, with its faster onset of OA efficacy and lower rates of related discontinuations, might provide efficacy advantages in the treatment of OA pain." | 2.71 | Pain management in osteoarthritis: a focus on onset of efficacy--a comparison of rofecoxib, celecoxib, acetaminophen, and nabumetone across four clinical trials. ( Battisti, WP; Geba, GP; Katz, NP; Kivitz, AJ; Matsumoto, AK; Polis, AB; Weaver, AL, 2004) |
| " Furthermore, there have been recent concerns over the safety profile of paracetamol, with reports of gastrointestinal, cardiovascular, hepatic and renal adverse events." | 2.61 | Safety of Paracetamol in Osteoarthritis: What Does the Literature Say? ( Arden, N; Avouac, B; Conaghan, PG; Migliore, A; Rizzoli, R, 2019) |
| "The evaluation of the updated 'My Joint Pain' website didn't find significant improvements in terms of health education, but it may help delivering useful information about self-management and appropriate use of pharmacological treatments." | 1.56 | My joint pain, a web-based resource, effects on education and quality of care at 24 months. ( Bennell, KL; Dickson, C; Dobson, F; Fransen, M; Hunter, DJ; Jones, G; Urban, H; Wang, X, 2020) |
| "To describe the epidemiology of joint pains and document analgesics usage in an African context." | 1.46 | Joint pain epidemiology and analgesic usage in Madagascar. ( Ralandison, S; Randriatsarafara, FM; Samison, LH, 2017) |
| " There is limited literature on the chronic use of opioids pre-TKA and post-TKA." | 1.46 | Chronic Use of Opioids Before and After Total Knee Arthroplasty: A Retrospective Cohort Study. ( Graves, SE; Hansen, CA; Inacio, MCS; Pratt, NL; Roughead, EE, 2017) |
| "Arthralgia is among the most frequent musculoskeletal symptoms occurring in patients with chronic lymphocytic thyroiditis (CLT), often causing pain and physical impairment over extended periods of time." | 1.31 | Clinical manifestations and outcome of polyarthralgia associated with chronic lymphocytic thyroiditis. ( Cozzi, F; Pianon, M; Punzi, L; Ramonda, R; Schiavon, F; Sfriso, P; Todesco, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.70) | 18.2507 |
| 2000's | 14 (37.84) | 29.6817 |
| 2010's | 20 (54.05) | 24.3611 |
| 2020's | 2 (5.41) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Urban, H | 1 |
| Bennell, KL | 1 |
| Dickson, C | 1 |
| Dobson, F | 1 |
| Fransen, M | 1 |
| Jones, G | 2 |
| Hunter, DJ | 2 |
| Reamy, BV | 1 |
| Servey, JT | 1 |
| Williams, PM | 1 |
| Hoag, SD | 1 |
| Chung, K | 1 |
| Samison, LH | 1 |
| Randriatsarafara, FM | 1 |
| Ralandison, S | 1 |
| Leopoldino, AO | 1 |
| Machado, GC | 1 |
| Ferreira, PH | 1 |
| Pinheiro, MB | 1 |
| Day, R | 1 |
| McLachlan, AJ | 1 |
| Ferreira, ML | 1 |
| Gebreselassie, A | 1 |
| Aduli, F | 1 |
| Howell, CD | 1 |
| Wiet, SG | 1 |
| Boyle, KE | 1 |
| Bass, MB | 1 |
| Conaghan, PG | 2 |
| Arden, N | 1 |
| Avouac, B | 1 |
| Migliore, A | 1 |
| Rizzoli, R | 1 |
| Petersen, KK | 1 |
| Simonsen, O | 1 |
| Olesen, AE | 1 |
| Mørch, CD | 1 |
| Arendt-Nielsen, L | 1 |
| Kingsbury, SR | 1 |
| Hensor, EM | 1 |
| Walsh, CA | 1 |
| Hochberg, MC | 1 |
| Ma, J | 1 |
| Talukdar, R | 1 |
| Gainers-Hasugluw, V | 1 |
| Hill, CL | 1 |
| March, LM | 1 |
| Aitken, D | 1 |
| Lester, SE | 1 |
| Battersby, R | 1 |
| Hynes, K | 1 |
| Fedorova, T | 1 |
| Proudman, SM | 1 |
| James, M | 1 |
| Cleland, LG | 1 |
| Sanzone, AG | 1 |
| Simental-Mendía, M | 1 |
| Vílchez-Cavazos, JF | 1 |
| Peña-Martínez, VM | 1 |
| Said-Fernández, S | 1 |
| Lara-Arias, J | 1 |
| Martínez-Rodríguez, HG | 1 |
| Sulich, A | 1 |
| Hansen, CA | 1 |
| Inacio, MCS | 1 |
| Pratt, NL | 1 |
| Roughead, EE | 1 |
| Graves, SE | 1 |
| Oliveras-Moreno, JM | 1 |
| Hernandez-Pacheco, E | 1 |
| Oliveras-Quintana, T | 1 |
| Infante-Cossio, P | 1 |
| Gutierrez-Perez, JL | 1 |
| Merkle, D | 1 |
| McDonald, DD | 1 |
| Verkleij, SP | 1 |
| Luijsterburg, PA | 1 |
| Koes, BW | 1 |
| Bohnen, AM | 1 |
| Bierma-Zeinstra, SM | 1 |
| Dixson, M | 1 |
| Wark, JD | 1 |
| Bensen, W | 1 |
| Recknor, C | 1 |
| Ryabitseva, O | 1 |
| Chiodo, J | 1 |
| Mesenbrink, P | 1 |
| de Villiers, TJ | 1 |
| Singh, K | 1 |
| Sharma, R | 1 |
| Rai, J | 1 |
| Ripa, SR | 1 |
| McCarberg, BH | 1 |
| Munera, C | 1 |
| Wen, W | 1 |
| Landau, CJ | 1 |
| Atamaz, FC | 1 |
| Durmaz, B | 1 |
| Baydar, M | 1 |
| Demircioglu, OY | 1 |
| Iyiyapici, A | 1 |
| Kuran, B | 1 |
| Oncel, S | 1 |
| Sendur, OF | 1 |
| Punzi, L | 1 |
| Sfriso, P | 1 |
| Pianon, M | 1 |
| Schiavon, F | 1 |
| Ramonda, R | 1 |
| Cozzi, F | 1 |
| Todesco, S | 1 |
| Battisti, WP | 1 |
| Katz, NP | 1 |
| Weaver, AL | 1 |
| Matsumoto, AK | 1 |
| Kivitz, AJ | 1 |
| Polis, AB | 1 |
| Geba, GP | 1 |
| Zylicz, Z | 1 |
| Krajnik, M | 1 |
| Stöve, J | 1 |
| Dalton, JD | 1 |
| Schweinle, JE | 1 |
| Federman, AD | 1 |
| Litke, A | 1 |
| Morrison, RS | 1 |
| Ahrenstorf, G | 1 |
| Burkhardt, O | 1 |
| Witte, T | 1 |
| Stoll, M | 1 |
| Schmidt, RE | 1 |
| Petitpain, N | 1 |
| Goffinet, L | 1 |
| Cosserat, F | 1 |
| Trechot, P | 1 |
| Cuny, JF | 1 |
| Fortina, F | 1 |
| Agllata, S | 1 |
| Ragazzoni, E | 1 |
| Sacco, A | 1 |
| Cardillo, V | 1 |
| Travaglini, S | 1 |
| Brini, P | 1 |
| Cavagnino, A | 1 |
| Creamer, P | 1 |
| Rovetta, G | 1 |
| Baratto, L | 1 |
| Farinelli, G | 1 |
| Monteforte, P | 1 |
| Sangdee, C | 1 |
| Teekachunhatean, S | 1 |
| Sananpanich, K | 1 |
| Sugandhavesa, N | 1 |
| Chiewchantanakit, S | 1 |
| Pojchamarnwiputh, S | 1 |
| Jayasvasti, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Platelet Rich Plasma in Knee Osteoarthritis: Establishing Clinical Guidelines to Predict and Maximize Outcomes[NCT05080075] | Early Phase 1 | 100 participants (Anticipated) | Interventional | 2021-12-02 | Active, not recruiting | ||
| A Randomized, Double-Blind Study Evaluating the Dose Conversion From Vicodin® to Buprenorphine Transdermal System (BTDS) in Subjects With Osteoarthritis (OA) Pain[NCT00312572] | Phase 3 | 204 participants (Actual) | Interventional | 2003-06-30 | Completed | ||
| Comparison Between Different Therapeutical Modalities Associated to Hamstring Flexibility Training: Randomized Clinical Trial[NCT03021850] | 34 participants (Actual) | Interventional | 2016-04-02 | Completed | |||
| A Randomized, Double-Blind, Parallel-Group Study Comparing the Safety and Effectiveness of Acetaminophen Extended Release (3900 mg/Day) and Ibuprofen (1200 mg/Day) in the Treatment of Ankle Sprains.[NCT00261560] | Phase 4 | 260 participants (Actual) | Interventional | Completed | |||
| Randomized, Double-Blind, Placebo-Controlled Trial, Parallel Design Used To Evaluate Pain, Endocrinologic Variations, Life Quality And Medication Use, After Electro-Acupuncture Treatment In Patients With Osteoarthritis Of The Knee[NCT02299713] | 160 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The indicator variable was 1 = completion, and 0 = noncompletion. For the primary efficacy analysis, the percentage of subjects who completed the double-blind phase was computed with its 95% confidence interval (CI) for each treatment regimen (starting dose of BTDS 10 or BTDS 20) across and within baseline Vicodin® stratum (15 to 22.5mg/day vs >22.5 to 30 mg/day as determined by the daily average hydrocodone dose during the run-in period). (NCT00312572)
Timeframe: 14 days
| Intervention | Percentage of Participants (Number) | ||
|---|---|---|---|
| 15 - 22.5 mg HCD (Stratum 1) | more than 22.5 - 30 mg HCD (Stratum 2) | Overall | |
| Combined Total | 85 | 82 | 84 |
| Double-blind BTDS 10/20 | 88 | 85 | 87 |
| Double-blind BTDS 20 | 83 | 79 | 82 |
7 reviews available for acetaminophen and Joint Pain
| Article | Year |
|---|---|
Henoch-Schönlein Purpura (IgA Vasculitis): Rapid Evidence Review.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, N | 2020 |
Paracetamol versus placebo for knee and hip osteoarthritis.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Arthralgia; Humans; Liver; Middle Aged; Osteoarthriti | 2019 |
Rheumatologic Diseases and the Liver.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthralgia; Biological | 2019 |
Safety of Paracetamol in Osteoarthritis: What Does the Literature Say?
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Arthralgia; Chemical and Drug Induced Liver Injury; D | 2019 |
Use of Nonopioid Analgesics and the Impact on Patient Outcomes.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; An | 2016 |
[Conservative therapy of arthritis].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Chondr | 2005 |
Osteoarthritis pain and its treatment.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthro | 2000 |
11 trials available for acetaminophen and Joint Pain
| Article | Year |
|---|---|
Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose.
Topics: Acetaminophen; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Cartilage, Art | 2016 |
Leukocyte-poor platelet-rich plasma is more effective than the conventional therapy with acetaminophen for the treatment of early knee osteoarthritis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Arthralgia; Female; Humans; Injections, Intra-Articular; Kn | 2016 |
Efficacy and safety of sodium hyaluronate in the treatment of Wilkes stage II disease.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Arthralgia; Drug Combinations; Drug-Related Side E | 2008 |
Effectiveness of diclofenac versus acetaminophen in primary care patients with knee osteoarthritis: [NTR1485], DIPA-trial: design of a randomized clinical trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; | 2010 |
Treatment with acetaminophen/paracetamol or ibuprofen alleviates post-dose symptoms related to intravenous infusion with zoledronic acid 5 mg.
Topics: Acetaminophen; Aged; Arthralgia; Body Temperature; Bone Density Conservation Agents; Diphosphonates; | 2012 |
Diacerein as adjuvant to diclofenac sodium in osteoarthritis knee.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anthraquinones; Anti-Inflammatory Age | 2012 |
A randomized, 14-day, double-blind study evaluating conversion from hydrocodone/acetaminophen (Vicodin) to buprenorphine transdermal system 10 μg/h or 20 μg/h in patients with osteoarthritis pain.
Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Aged; Analgesics, Opioid; Anti-Infla | 2012 |
Comparison of the efficacy of transcutaneous electrical nerve stimulation, interferential currents, and shortwave diathermy in knee osteoarthritis: a double-blind, randomized, controlled, multicenter study.
Topics: Acetaminophen; Aged; Analysis of Variance; Arthralgia; Combined Modality Therapy; Diathermy; Double- | 2012 |
Pain management in osteoarthritis: a focus on onset of efficacy--a comparison of rofecoxib, celecoxib, acetaminophen, and nabumetone across four clinical trials.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Butano | 2004 |
Randomized controlled noninferiority trial to compare extended release acetaminophen and ibuprofen for the treatment of ankle sprains.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Ankle Injuries; Arthralgia; Contusions; Double-Blind Method | 2006 |
Electroacupuncture versus diclofenac in symptomatic treatment of osteoarthritis of the knee: a randomized controlled trial.
Topics: Acetaminophen; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Com | 2002 |
19 other studies available for acetaminophen and Joint Pain
| Article | Year |
|---|---|
My joint pain, a web-based resource, effects on education and quality of care at 24 months.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Australia; Female; Follow- | 2020 |
Severe polyarthralgia, high-grade fever, diffuse maculopapular rash on trunk and extremities · Dx?
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Ankle; Anti-Inflammatory Agents; Arthralgia; Caribbe | 2017 |
Joint pain epidemiology and analgesic usage in Madagascar.
Topics: Acetaminophen; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Analgesics; Anal | 2017 |
Increasing Participation in Daily Activities among US Adults with Arthritis.
Topics: Acetaminophen; Activities of Daily Living; Aged; Analgesics, Non-Narcotic; Arthralgia; Exercise; Fem | 2019 |
Pain inhibitory mechanisms and response to weak analgesics in patients with knee osteoarthritis.
Topics: Acetaminophen; Aged; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; A | 2019 |
How do people with knee osteoarthritis use osteoarthritis pain medications and does this change over time? Data from the Osteoarthritis Initiative.
Topics: Acetaminophen; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Body Mass Inde | 2013 |
Pilot open observations on doxycycline treatment for erosive osteoarthritis of the hand.
Topics: Acetaminophen; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Doxycycli | 2015 |
Acetaminophen in Perspective.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Arthralgia; Female; Humans; Male; Osteoarthritis; Tre | 2016 |
Chronic Use of Opioids Before and After Total Knee Arthroplasty: A Retrospective Cohort Study.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Arthralgia; Arthroplasty, Replacement, K | 2017 |
Use of recommended osteoarthritis pain treatment by older adults.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 2009 |
Pediatric rash and joint pain: a case review.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Ankle Joint; Anti-Bacterial Agents; Arthralgia; Ceftriaxone | 2010 |
Clinical manifestations and outcome of polyarthralgia associated with chronic lymphocytic thyroiditis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Arthralgia; Female; Hormone Replacement Therapy; Hum | 2002 |
Paracetamol/acetaminophen-induced fever and malaise in a juvenile patient.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Arthralgia; Female; Fever; Humans; Knee Joint | 2005 |
NSAIDs better than acetaminophen for mild-to-moderate OA pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Humans | 2006 |
Association of age with analgesic use for back and joint disorders in outpatient settings.
Topics: Acetaminophen; Adult; Age Distribution; Age Factors; Aged; Ambulatory Care Facilities; Analgesics; A | 2006 |
[Chikungunya: fever and joint pains after vacation in a tropical area].
Topics: Acetaminophen; Adult; Alphavirus Infections; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infl | 2008 |
Recurrent fever, chills, and arthralgia with local anesthetics containing epinephrine-metabisulfite.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Arthralgia; Carticaine; Chills; | 2008 |
[Chronic pain during dialysis. Pharmacologic therapy and its costs].
Topics: Acetaminophen; Analgesics; Arthralgia; Buprenorphine; Chronic Disease; Codeine; Disability Evaluatio | 1999 |
Three-month follow-up of shoulder-hand syndrome induced by phenobarbital and treated with gabapentin.
Topics: Acetaminophen; Acetates; Amines; Analgesics; Anticonvulsants; Arthralgia; Cyclohexanecarboxylic Acid | 2001 |