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acetaminophen and Jaundice

acetaminophen has been researched along with Jaundice in 20 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.

Research Excerpts

ExcerptRelevanceReference
"We evaluated the effect of hemolysis, icterus and lipemia on 3 acetaminophen assays: namely the Syva® EMIT®, the Microgenics DRI® assay, and the Roche assay on a Roche Cobas® c501 or an Integra 800 analyzer."7.88Effect of hemolysis, icterus, and lipemia on three acetaminophen assays: Potential medical consequences of false positive results. ( Fan, SL; Kellogg, MD; Zhang, YV, 2018)
"Two family members developed severe hepatitic dysfunction in association with infectious mononucleosis and acetaminophen administration."7.65Acetaminophen and hepatic dysfunction in infectious mononucleosis. ( Manning, IH; Meyer, AA; Neelon, FA; Rosenberg, DM, 1977)
"We evaluated the effect of hemolysis, icterus and lipemia on 3 acetaminophen assays: namely the Syva® EMIT®, the Microgenics DRI® assay, and the Roche assay on a Roche Cobas® c501 or an Integra 800 analyzer."3.88Effect of hemolysis, icterus, and lipemia on three acetaminophen assays: Potential medical consequences of false positive results. ( Fan, SL; Kellogg, MD; Zhang, YV, 2018)
"Acetaminophen was falsely detected in the plasma of a severely jaundiced patient, and a methodologic interference from bilirubin was suspected."3.72False-positive acetaminophen results in a hyperbilirubinemic patient. ( Bazooband, A; Bertholf, RL; Johannsen, LM; Mansouri, V, 2003)
"Two family members developed severe hepatitic dysfunction in association with infectious mononucleosis and acetaminophen administration."3.65Acetaminophen and hepatic dysfunction in infectious mononucleosis. ( Manning, IH; Meyer, AA; Neelon, FA; Rosenberg, DM, 1977)
" There was no lysozymuria with severe uraemic heart failure, aspirin and paracetamol poisoning, or severe jaundice, nor in two cases of acute glomerulonephritis."3.65Lysozymuria and acute disorders of renal function. ( De Silva, KL; Harrison, JF; Parker, RW, 1973)
"Paracetamol-induced haemolysis in G6PD deficiency is a rare complication and mostly reported in children."1.40Glucose-6-phosphate dehydrogenase deficiency: an unusual cause of acute jaundice after paracetamol overdose. ( Phillpotts, S; Sen, S; Tash, E, 2014)
"Simvastatin is a substrate of CYP3A4 enzyme."1.38Paracetamol and simvastatin: a potential interaction resulting in hepatotoxicity. ( Gumbrevičius, G; Stankevičius, E; Sveikata, A; Sveikatienė, R, 2012)
"Acetaminophen metabolites were measured by high-performance liquid chromatography and production of the acetaminophen glucuronide conjugate was quantified by the area under plasma concentration-time curve (AUC) from 0 to 2 hr, standardized by the AUC value for acetaminophen in the same animal (glucuronidation ratio = AUC acetaminophen glucuronide/AUC acetaminophen)."1.28Biotransformation and toxicity of acetaminophen in congenic RHA rats with or without a hereditary deficiency in bilirubin UDP-glucuronosyltransferase. ( Chow, SY; de Morais, SM; Wells, PG, 1992)
"Marked cyanosis was observed in experimental cats within 4 hours after administration of one 325-mg tablet."1.25Acetaminophen toxicosis in the cat. ( Duncan, JR; Finco, DC; Prasse, KW; Schall, WD, 1975)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199011 (55.00)18.7374
1990's2 (10.00)18.2507
2000's1 (5.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, YV1
Fan, SL1
Kellogg, MD1
Phillpotts, S1
Tash, E1
Sen, S1
Olson, KR1
Davarpanah, AH1
Schaefer, EA1
Elias, N1
Misdraji, J1
Vega, AB1
Andreu, V1
Perelló, A1
Chahri, N1
Córdova, H1
Abad, A1
Barenys, M1
Sabaté, M1
Ibáñez, L1
Pérez, E1
Vidal, X1
Buti, M1
Xiol, X1
Mas, A1
Guarner, C1
Forné, M1
Solà, R1
Castellote, J1
Rigau, J1
Laporte, JR1
Gumbrevičius, G1
Sveikata, A1
Sveikatienė, R1
Stankevičius, E1
Bertholf, RL1
Johannsen, LM1
Bazooband, A1
Mansouri, V1
Levinson, M1
Licht, H1
Seeff, LB1
Zimmerman, HJ1
Hantson, P1
Vekemans, MC1
Laterre, PF1
Vanormelingen, P1
Mahieu, P1
Koerner, MM1
Rosenberg, DM1
Meyer, AA1
Manning, IH1
Neelon, FA1
Finco, DC1
Duncan, JR1
Schall, WD1
Prasse, KW1
Goranov, I1
Avramova, K1
de Morais, SM1
Chow, SY1
Wells, PG1
Dölle, W1
Rueff, B1
Benhamou, JP1
Harrison, JF1
Parker, RW1
De Silva, KL1
Goulding, R1
Goertz, J1
Williams, R1
Proudfoot, AT1
Wright, N1

Reviews

2 reviews available for acetaminophen and Jaundice

ArticleYear
[Prolonged fever and jaundice in a patient with alcoholic liver disease].
    Gastroenterologia y hepatologia, 2010, Volume: 33, Issue:8

    Topics: Acetaminophen; Adult; Animals; Animals, Domestic; Antibodies, Bacterial; Antipyretics; Ascites; Chem

2010
Acute hepatic necrosis and fulminant hepatic failure.
    Gut, 1973, Volume: 14, Issue:10

    Topics: Acetaminophen; Acute Disease; Alanine Transaminase; Animals; Blood Coagulation Disorders; Brain Dise

1973

Other Studies

18 other studies available for acetaminophen and Jaundice

ArticleYear
Effect of hemolysis, icterus, and lipemia on three acetaminophen assays: Potential medical consequences of false positive results.
    Clinica chimica acta; international journal of clinical chemistry, 2018, Volume: 487

    Topics: Acetaminophen; False Positive Reactions; Hemolysis; Humans; Hyperlipidemias; Jaundice

2018
Glucose-6-phosphate dehydrogenase deficiency: an unusual cause of acute jaundice after paracetamol overdose.
    European journal of haematology, 2014, Volume: 93, Issue:5

    Topics: Acetaminophen; Acute Disease; Adult; Antipyretics; Drug Overdose; Female; Glucosephosphate Dehydroge

2014
Case 2-2017. An 18-Year-Old Woman with Acute Liver Failure.
    The New England journal of medicine, 2017, 01-19, Volume: 376, Issue:3

    Topics: Abdomen; Acetaminophen; Adolescent; Diagnosis, Differential; Female; Hepatolenticular Degeneration;

2017
Paracetamol in therapeutic dosages and acute liver injury: causality assessment in a prospective case series.
    BMC gastroenterology, 2011, Jul-15, Volume: 11

    Topics: Acetaminophen; Adolescent; Adult; Aged, 80 and over; Analgesics, Non-Narcotic; Drug Hypersensitivity

2011
Paracetamol and simvastatin: a potential interaction resulting in hepatotoxicity.
    Medicina (Kaunas, Lithuania), 2012, Volume: 48, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Coronary Artery Bypass; Cytochrome P-450 CYP3A; Drug

2012
False-positive acetaminophen results in a hyperbilirubinemic patient.
    Clinical chemistry, 2003, Volume: 49, Issue:4

    Topics: Acetaminophen; Adolescent; Bilirubin; False Positive Reactions; Humans; Hyperbilirubinemia; Jaundice

2003
Ulcer, back pain, and jaundice in an alcoholic.
    Hospital practice (Office ed.), 1983, Volume: 18, Issue:10

    Topics: Acetaminophen; Adult; Alcoholism; Back Pain; Chemical and Drug Induced Liver Injury; Dextropropoxyph

1983
Apparent potentiation of acetaminophen hepatotoxicity by alcohol.
    Annals of internal medicine, 1980, Volume: 92, Issue:4

    Topics: Acetaminophen; Drug Synergism; Ethanol; Humans; Jaundice; Liver; Male; Middle Aged; Necrosis

1980
Heart donation after fatal acetaminophen poisoning.
    Journal of toxicology. Clinical toxicology, 1997, Volume: 35, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Coma; Female; Heart Transplantation;

1997
Acetaminophen and hepatic dysfunction in infectious mononucleosis.
    Southern medical journal, 1977, Volume: 70, Issue:6

    Topics: Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Infectious Mononucleos

1977
Acetaminophen toxicosis in the cat.
    Journal of the American Veterinary Medical Association, 1975, Mar-01, Volume: 166, Issue:5

    Topics: Acetaminophen; Administration, Oral; Anemia; Animals; Bilirubin; Blood Urea Nitrogen; Cat Diseases;

1975
[Study of liver glucuronidase function in indirect hyperbilirubinemia and liver cirrhosis].
    Problemi na khigienata, 1975, Volume: 1

    Topics: Acetaminophen; Bilirubin; Biological Transport; Free Radicals; Glucuronidase; Humans; Hyperbilirubin

1975
Biotransformation and toxicity of acetaminophen in congenic RHA rats with or without a hereditary deficiency in bilirubin UDP-glucuronosyltransferase.
    Toxicology and applied pharmacology, 1992, Volume: 117, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Biotransformation; Glucosyltransferase

1992
[Liver damage following paracetamole poisoning].
    Der Internist, 1972, Volume: 13, Issue:10

    Topics: Acetaminophen; Acute Kidney Injury; Animals; Autopsy; Blood Sedimentation; Chemical and Drug Induced

1972
Lysozymuria and acute disorders of renal function.
    Journal of clinical pathology, 1973, Volume: 26, Issue:4

    Topics: Acetaminophen; Acute Disease; Aspirin; Electroshock; Glomerulonephritis; Heart Failure; Humans; Hypo

1973
Acetaminophen poisoning.
    Pediatrics, 1973, Volume: 52, Issue:6

    Topics: Acetaminophen; Adolescent; Catalogs, Drug as Topic; Charcoal; Chemical and Drug Induced Liver Injury

1973
Histological appearances in fulminant hepatic failure with reference to aetiology, time of survival and role of immunological processes.
    Digestion, 1973, Volume: 8, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Cell Nucleus; Chemical and Drug Induced Liver Injury; Haloth

1973
Acute paracetamol poisoning.
    British medical journal, 1970, Sep-05, Volume: 3, Issue:5722

    Topics: Acetaminophen; Acidosis; Acute Disease; Acute Kidney Injury; Adolescent; Adult; Aged; Chemical and D

1970