acetaminophen has been researched along with Intracranial Hypertension in 11 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Intracranial Hypertension: Increased pressure within the cranial vault. This may result from several conditions, including HYDROCEPHALUS; BRAIN EDEMA; intracranial masses; severe systemic HYPERTENSION; PSEUDOTUMOR CEREBRI; and other disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 42-year-old woman receiving intensive care for fulminant hepatic failure secondary to acetaminophen toxicity developed cerebral edema and intracranial hypertension refractory to standard pharmacotherapy and respiratory support measures." | 7.81 | Indomethacin for treatment of refractory intracranial hypertension secondary to acute liver failure. ( Abdelhak, TM; Jones, MC; Lasak-Myall, T; Varelas, PN, 2015) |
| "A 42-year-old woman receiving intensive care for fulminant hepatic failure secondary to acetaminophen toxicity developed cerebral edema and intracranial hypertension refractory to standard pharmacotherapy and respiratory support measures." | 3.81 | Indomethacin for treatment of refractory intracranial hypertension secondary to acute liver failure. ( Abdelhak, TM; Jones, MC; Lasak-Myall, T; Varelas, PN, 2015) |
| "A comatose 23-year-old woman with acute liver failure due to an overdose of acetaminophen had indications of intracranial hypertension and underwent liver transplantation." | 3.78 | Therapeutic hypothermia for treatment of intractable intracranial hypertension after liver transplantation. ( Fox, AD; Holena, DN; Levine, JM; Mills, AM; Tolstoy, NS, 2012) |
| "In patients with FHF and cerebral edema from acetaminophen overdose, prolonged therapeutic hypothermia could potentially be used as a life saving therapy and a bridge to hepatic and neurological recovery." | 3.75 | Prolonged hypothermia as a bridge to recovery for cerebral edema and intracranial hypertension associated with fulminant hepatic failure. ( Jacob, S; Jacobs, ER; Kandiah, P; Khan, A; Nanchal, R, 2009) |
| "Acute liver failure is a rare but life-threatening disease that can lead to progressive encephalopathy, intracranial hypertension, and multiorgan failure." | 2.58 | Modern Management of Acute Liver Failure. ( Khan, R; Koppe, S, 2018) |
| "Adult critically ill patients with acute liver failure presenting with grade III/IV hepatic encephalopathy (n = 629) prospectively enrolled between March 2004 and August 2011." | 1.40 | Outcomes and complications of intracranial pressure monitoring in acute liver failure: a retrospective cohort study. ( Battenhouse, H; Durkalski, V; Fix, OK; Karvellas, CJ; Lee, WM; Sanders, C, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, R | 1 |
| Koppe, S | 1 |
| Bernal, W | 2 |
| Hyyrylainen, A | 1 |
| Gera, A | 1 |
| Audimoolam, VK | 1 |
| McPhail, MJ | 2 |
| Auzinger, G | 1 |
| Rela, M | 1 |
| Heaton, N | 1 |
| O'Grady, JG | 1 |
| Wendon, J | 1 |
| Williams, R | 1 |
| Karvellas, CJ | 1 |
| Fix, OK | 1 |
| Battenhouse, H | 1 |
| Durkalski, V | 1 |
| Sanders, C | 1 |
| Lee, WM | 1 |
| Singanayagam, A | 1 |
| Kriese, S | 1 |
| Heneghan, MA | 1 |
| Jones, MC | 1 |
| Lasak-Myall, T | 1 |
| Abdelhak, TM | 1 |
| Varelas, PN | 1 |
| Jacob, S | 1 |
| Khan, A | 1 |
| Jacobs, ER | 1 |
| Kandiah, P | 1 |
| Nanchal, R | 1 |
| Holena, DN | 1 |
| Tolstoy, NS | 1 |
| Mills, AM | 1 |
| Fox, AD | 1 |
| Levine, JM | 1 |
| Jalan, R | 1 |
| Pollok, A | 1 |
| Shah, SH | 1 |
| Madhavan, K | 1 |
| Simpson, KJ | 1 |
| Bailey, B | 1 |
| Blais, R | 1 |
| Letarte, A | 1 |
| Ducros, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Center Trial to Study Acute Liver Failure in Adults[NCT00518440] | 3,488 participants (Actual) | Observational | 1998-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for acetaminophen and Intracranial Hypertension
| Article | Year |
|---|---|
Modern Management of Acute Liver Failure.
Topics: Acetaminophen; Acetylcysteine; Biomarkers; Blood Coagulation Disorders; Brain Diseases; Free Radical | 2018 |
Update on acute liver failure.
Topics: Acetaminophen; Adrenal Cortex Hormones; Critical Care; Hepatitis, Autoimmune; Humans; Intracranial H | 2015 |
Current management of acute liver failure.
Topics: Acetaminophen; Critical Care; Drug Overdose; Hepatic Encephalopathy; Humans; Intracranial Hypertensi | 2015 |
[Acute and chronic headaches].
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2006 |
7 other studies available for acetaminophen and Intracranial Hypertension
| Article | Year |
|---|---|
Lessons from look-back in acute liver failure? A single centre experience of 3300 patients.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Critical Care; Emergencies; Female; Hepatic Encephal | 2013 |
Outcomes and complications of intracranial pressure monitoring in acute liver failure: a retrospective cohort study.
Topics: Acetaminophen; Adult; Case-Control Studies; Cerebrovascular Circulation; Female; Hepatic Encephalopa | 2014 |
Indomethacin for treatment of refractory intracranial hypertension secondary to acute liver failure.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injur | 2015 |
Prolonged hypothermia as a bridge to recovery for cerebral edema and intracranial hypertension associated with fulminant hepatic failure.
Topics: Acetaminophen; Adult; Brain; Brain Edema; Female; Humans; Hypothermia; Hypothermia, Induced; Intracr | 2009 |
Therapeutic hypothermia for treatment of intractable intracranial hypertension after liver transplantation.
Topics: Acetaminophen; Drug Overdose; Female; Humans; Hypothermia, Induced; Intracranial Hypertension; Intra | 2012 |
Liver derived pro-inflammatory cytokines may be important in producing intracranial hypertension in acute liver failure.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Cytokines; Female; Hepatectomy; Humans; Intracr | 2002 |
Status epilepticus after a massive intravenous N-acetylcysteine overdose leading to intracranial hypertension and death.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Child, Preschool; Drug Overdose; Fatal Outc | 2004 |